Outputs (2)

High resolution 3D printed biocatalytic reactor core with optimized efficiency for continuous flow synthesis (2024)
Journal Article
Attwood, S. J., Leech, D., He, Y., Croft, A., Hague, R. J., Irvine, D. J., Wildman, R. D., & Pordea, A. (2025). High resolution 3D printed biocatalytic reactor core with optimized efficiency for continuous flow synthesis. Chemical Engineering Science, 305, Article 121156. https://doi.org/10.1016/j.ces.2024.121156

3D printing has the potential to transform biocatalytic continuous flow reactor technology, where precise control of topology is essential for maximizing reactor performance. By embedding enzymatic catalysts in polymer hydrogel networks, continuous s... Read More about High resolution 3D printed biocatalytic reactor core with optimized efficiency for continuous flow synthesis.

Iron-catalyzed indolizine synthesis from pyridines, diazo compounds, and alkynes (2017)
Journal Article
Douglas, T., Pordea, A., & Dowden, J. (in press). Iron-catalyzed indolizine synthesis from pyridines, diazo compounds, and alkynes. Organic Letters, 19(23), https://doi.org/10.1021/acs.orglett.7b03252

The iron (III) catalyzed synthesis of indolizines from commercially available alkyne, pyridine, and diazo precursors is reported. This mild, expedient method is tolerant of various solvents and proceeds with as little as 0.25 mol % [Fe(TPP)Cl]. Signi... Read More about Iron-catalyzed indolizine synthesis from pyridines, diazo compounds, and alkynes.