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Dr RACHAEL TARLINTON's Outputs (79)

Genomic characterization and cross-species transmission potential of hedgehog coronavirus (2024)
Journal Article
Cruz, A. V., Santos-Silva, S., Queirós-Reis, L., Rodrigues, C., Soeiro, V., Tarlinton, R. E., & Mesquita, J. R. (2024). Genomic characterization and cross-species transmission potential of hedgehog coronavirus. One Health, 19, Article 100940. https://doi.org/10.1016/j.onehlt.2024.100940

In the 21st century, three betacoronaviruses (SARS-CoV, MERS-CoV and SARS-CoV-2) have emerged in humans worldwide as a result of animal spillover, causing severe respiratory infections and resulting in more than seven million deaths. In 2013, a novel... Read More about Genomic characterization and cross-species transmission potential of hedgehog coronavirus.

High prevalence and risk factors of feline leukemia virus infection in Chilean urban cats (Felis catus). (2024)
Journal Article
Castillo-Aliaga, C., Castro-Seriche, S., Jerez-Morales, A., & Tarlinton, R. (2024). High prevalence and risk factors of feline leukemia virus infection in Chilean urban cats (Felis catus). Research in Veterinary Science, 180, Article 105403. https://doi.org/10.1016/j.rvsc.2024.105403

Feline Leukemia Virus is a retrovirus causing fatal disease in domestic cats. While FeLV has been controlled in many countries, it remains a major concern in Latin American countries. This study conducted an epidemiological survey of FeLV in 182 Chil... Read More about High prevalence and risk factors of feline leukemia virus infection in Chilean urban cats (Felis catus)..

Koala retrovirus and neoplasia: correlation and underlying mechanisms (2024)
Journal Article
Tarlinton, R., & Greenwood, A. D. (2024). Koala retrovirus and neoplasia: correlation and underlying mechanisms. Current Opinion in Virology, 67, Article 101427. https://doi.org/10.1016/j.coviro.2024.101427

The koala retrovirus, KoRV, is one of the few models for understanding the health consequences of retroviral colonization of the germline. Such colonization events transition exogenous infectious retroviruses to Mendelian traits or endogenous retrovi... Read More about Koala retrovirus and neoplasia: correlation and underlying mechanisms.

Multiple novel caliciviruses identified from stoats (Mustela erminea) in the United Kingdom (2024)
Journal Article
Hinds, J., Apaa, T., Parry, R. H., Withers, A. J., MacKenzie, L., Staley, C., Morrison, J., Bennett, M., Bremner-Harrison, S., Chadwick, E. A., Hailer, F., Harrison, S. W., Lambin, X., Loose, M., Mathews, F., Tarlinton, R., & Blanchard, A. (2024). Multiple novel caliciviruses identified from stoats (Mustela erminea) in the United Kingdom. Access Microbiology, 6(7), Article 000813.v4. https://doi.org/10.1099/acmi.0.000813.v4

The Caliciviridae family, comprising positive-sense RNA viruses, is characterised by its non-enveloped, small virions, broad host range, and notable tendency for host switching. These viruses are primarily associated with gastroenteric disease, thoug... Read More about Multiple novel caliciviruses identified from stoats (Mustela erminea) in the United Kingdom.

Version 3: Multiple novel caliciviruses identified from stoats (Mustela erminea) in the United Kingdom (2024)
Preprint / Working Paper
Hinds, J., Apaa, T., Parry, R. H., Withers, A. J., MacKenzie, L., Staley, C., Morrison, J., Bennett, M., Bremner-Harrison, S., Chadwick, E. A., Hailer, F., Harrison, S. W., Lambin, X., Loose, M., Mathews, F., Tarlinton, R., & Blanchard, A. (2024). Version 3: Multiple novel caliciviruses identified from stoats (Mustela erminea) in the United Kingdom

The Caliciviridae family, comprising positive-sense RNA viruses, is characterised by its non-enveloped, small virions, broad host range, and notable tendency for host switching. These viruses are primarily associated with gastroenteric disease, thoug... Read More about Version 3: Multiple novel caliciviruses identified from stoats (Mustela erminea) in the United Kingdom.

Treatment considerations for bluetongue virus serotype-3 cases in sheep (2024)
Journal Article
Lovatt, F., Tarlinton, R., & Groenevelt, M. (2024). Treatment considerations for bluetongue virus serotype-3 cases in sheep. In Practice, 46(4), 198-203. https://doi.org/10.1002/inpr.429

Background: Bluetongue virus (BTV) serotype-3 (BTV-3) has been circulating in the Netherlands since September 2023 and was first reported in Kent in the UK in November 2023, picked up via the annual bluetongue surveillance programme. It is a highly p... Read More about Treatment considerations for bluetongue virus serotype-3 cases in sheep.

Ocrelizumab B cell depletion has no effect on HERV RNA expression in PBMC in MS patients (2024)
Journal Article
Tarlinton, R., Tanasescu, R., Shannon-Lowe, C., & Gran, B. (2024). Ocrelizumab B cell depletion has no effect on HERV RNA expression in PBMC in MS patients. Multiple Sclerosis and Related Disorders, 86, Article 105597. https://doi.org/10.1016/j.msard.2024.105597

Background
Epstein barr virus (EBV) infection of B cells is now understood to be one of the triggering events for the development of Multiple Sclerosis (MS), a progressive immune-mediated disease of the central nervous system. EBV infection is also... Read More about Ocrelizumab B cell depletion has no effect on HERV RNA expression in PBMC in MS patients.

Lack of detection of SARS-CoV-2 in wildlife from Kerala, India in 2020–21 (2024)
Journal Article
Zachariah, A., Krishnankutty, S. P., Manazhi, J., Omanakuttan, V., Santosh, S., Blanchard, A., & Tarlinton, R. (2024). Lack of detection of SARS-CoV-2 in wildlife from Kerala, India in 2020–21. Access Microbiology, 6(1), Article 000686. https://doi.org/10.1099/acmi.0.000686.v3

Spillover of SARS-CoV-2 into a variety of wild and domestic animals has been an ongoing feature of the human pandemic. The establishment of a new reservoir in white-tailed deer in North America and increasing divergence of the viruses circulating in... Read More about Lack of detection of SARS-CoV-2 in wildlife from Kerala, India in 2020–21.

UK flockdown: A survey of smallscale poultry keepers and their understanding of governmental guidance on highly pathogenic avian influenza (HPAI) (2024)
Journal Article
McClaughlin, E., Elliott, S., Jewitt, S., Smallman-Raynor, M., Dunham, S., Parnell, T., Clark, M., & Tarlinton, R. (2024). UK flockdown: A survey of smallscale poultry keepers and their understanding of governmental guidance on highly pathogenic avian influenza (HPAI). Preventive Veterinary Medicine, 224, Article 106117. https://doi.org/10.1016/j.prevetmed.2024.106117

The scale of the current outbreak of highly pathogenic avian influenza (HPAI) due to the A/H5N1 virus in the United Kingdom is unprecedented. In addition to its economic impact on the commercial poultry sector, the disease has devastated wild bird co... Read More about UK flockdown: A survey of smallscale poultry keepers and their understanding of governmental guidance on highly pathogenic avian influenza (HPAI).

Veterinarians’ knowledge and experience of avian influenza and perspectives on control measures in the UK (2024)
Journal Article
Jewitt, S., McClaughlin, E., Elliott, S., Smallman-Raynor, M., Clark, M., Dunham, S., & Tarlinton, R. (2024). Veterinarians’ knowledge and experience of avian influenza and perspectives on control measures in the UK. Veterinary Record, 195(5), Article e3713. https://doi.org/10.1002/vetr.3713

Background
The scale of the outbreak of highly pathogenic avian influenza (HPAI) in 2021–23 due to the influenza A/H5N1 virus is unprecedented.

Methods
An online survey was designed to explore veterinarians’ experiences of and confidence in trea... Read More about Veterinarians’ knowledge and experience of avian influenza and perspectives on control measures in the UK.

Veterinarians' knowledge and experience of avian influenza and perspectives on control measures in the United Kingdom (2024)
Journal Article
Jewitt, S., Mcclaughlin, E., Elliott, S., Smallman-Raynor, M., Clark, M., Dunham, S., & Tarlinton, R. (2024). Veterinarians' knowledge and experience of avian influenza and perspectives on control measures in the United Kingdom. Veterinary Record, 195(5), Article e3713. https://doi.org/10.1002/vetr.3713

Background
The scale of the outbreak of highly pathogenic avian influenza (HPAI) in 2021–23 due to the influenza A/H5N1 virus is unprecedented.

Methods
An online survey was designed to explore veterinarians’ experiences of and confidence in trea... Read More about Veterinarians' knowledge and experience of avian influenza and perspectives on control measures in the United Kingdom.

Lack of detection of SARS-CoV-2 in British wildlife 2020–21 and first description of a stoat (Mustela erminea) Minacovirus (2023)
Journal Article
Apaa, T., Withers, A. J., Mackenzie, L., Staley, C., Dessi, N., Blanchard, A., Bennett, M., Bremner-Harrison, S., Chadwick, E. A., Hailer, F., Harrison, S. W. R., Lambin, X., Loose, M., Mathews, F., & Tarlinton, R. (2023). Lack of detection of SARS-CoV-2 in British wildlife 2020–21 and first description of a stoat (Mustela erminea) Minacovirus. Journal of General Virology, 104(12), https://doi.org/10.1099/jgv.0.001917

Repeat spillover of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) into new hosts has highlighted the critical role of cross-species transmission of coronaviruses and establishment of new reservoirs of virus in pandemic and epizootic sp... Read More about Lack of detection of SARS-CoV-2 in British wildlife 2020–21 and first description of a stoat (Mustela erminea) Minacovirus.

Ocrelizumab B cell depletion has no effect on HERV RNA expression in PBMC in MS patients (2023)
Preprint / Working Paper
Tarlinton, R., Tanescu, R., Shannon-Lowe, C., & Gran, B. (2023). Ocrelizumab B cell depletion has no effect on HERV RNA expression in PBMC in MS patients

Background Epstein Barr Virus (EBV) infection of B cells is now understood to be one of the triggering events for the development of Multiple Sclerosis (MS), a progressive immune-mediated disease of the central nervous system. EBV infection is also l... Read More about Ocrelizumab B cell depletion has no effect on HERV RNA expression in PBMC in MS patients.

COMPARISON BETWEEN SANGER, ILLUMINA AND NANOPORE SEQUENCING EVIDENCING INTRA-HOST VARIATION OF FELINE LEUKEMIA VIRUS THAT INFECTS DOMESTIC CATS. (2023)
Preprint / Working Paper
Castillo-Aliaga, C., Blanchard, A. M., Castro-Seriche, S., Hidalgo-Hermoso, E., Jerez-Morales, A., Loose, M. W., & Tarlinton, R. E. (2023). COMPARISON BETWEEN SANGER, ILLUMINA AND NANOPORE SEQUENCING EVIDENCING INTRA-HOST VARIATION OF FELINE LEUKEMIA VIRUS THAT INFECTS DOMESTIC CATS

Knowledge of Feline Leukemia Virus (FeLV) sequence variation has mainly been developed using Sanger sequencing methods. However, advances in next generation sequencing methods and their broad use in laboratories has been changing our understanding of... Read More about COMPARISON BETWEEN SANGER, ILLUMINA AND NANOPORE SEQUENCING EVIDENCING INTRA-HOST VARIATION OF FELINE LEUKEMIA VIRUS THAT INFECTS DOMESTIC CATS..

Antiviral activity of salt-coated materials against SARS-CoV-2 (2023)
Journal Article
Coleman, C. M., Wang, B., Wang, Y., Tapia-Brito, E., Chen, Z., Riffat, J., Riffat, S., Tarlinton, R., & Ghaemmaghami, A. (2023). Antiviral activity of salt-coated materials against SARS-CoV-2. Access Microbiology, 5(9), Article 000492. https://doi.org/10.1099/acmi.0.000492.v5

The SARS-CoV-2 pandemic demonstrated the importance of human coronaviruses and the need to develop materials to prevent the spread of emergent respiratory viruses. Coating of surfaces with antiviral materials is a major interest in controlling spread... Read More about Antiviral activity of salt-coated materials against SARS-CoV-2.

Lack of detection of SARS-CoV-2 in British wildlife 2020-21 and first description of a stoat (Mustela erminea) Minacovirus (2023)
Preprint / Working Paper
Apaa, T., Withers, A. J., McKenzie, L., Staley, C., Blanchard, A., Bennett, M., Bremner-Harrison, S., Chadwick, E. A., Hailer, F., Harrison, S. W., Lambin, X., Loose, M., Mathews, F., & Tarlinton, R. (2023). Lack of detection of SARS-CoV-2 in British wildlife 2020-21 and first description of a stoat (Mustela erminea) Minacovirus

Repeat spillover of SARS-CoV-2 into new hosts has highlighted the critical role of cross species transmission of coronaviruses and establishment of new reservoirs of virus in pandemic and epizootic spread of coronaviruses. Species particularly suscep... Read More about Lack of detection of SARS-CoV-2 in British wildlife 2020-21 and first description of a stoat (Mustela erminea) Minacovirus.

Version 4: Antiviral activity of salt-coated materials against SARS-CoV-2. (2023)
Preprint / Working Paper
Coleman, C. M., Wang, B., Wang, Y., Tapia-Brito, E., Chen, Z., Riffat, J., Riffat, S., Tarlinton, R., & Ghaemmaghami, A. Version 4: Antiviral activity of salt-coated materials against SARS-CoV-2

The SARS-CoV-2 pandemic demonstrated the importance of human coronaviruses and the need to develop materials to prevent the spread of emergent viruses. Here we describe that simple salt coating on a range of surfaces can degrade SARS-CoV-2.

Exploring the responses of smallscale poultry keepers to avian influenza regulations and guidance in the United Kingdom, with recommendations for improved biosecurity messaging (2023)
Journal Article
Jewitt, S., Smallman-Raynor, M., McClaughlin, E., Clark, M., Dunham, S., Elliott, S., Munro, A., Parnell, T., & Tarlinton, R. (2023). Exploring the responses of smallscale poultry keepers to avian influenza regulations and guidance in the United Kingdom, with recommendations for improved biosecurity messaging. Heliyon, 9(9), Article E19211. https://doi.org/10.1016/j.heliyon.2023.e19211

Understanding how smallscale (‘backyard’) poultry keepers interpret and respond to governmental directives designed to reduce the transmission of highly pathogenic avian influenza (HPAI) is of paramount importance in preparing for future HPAI outbrea... Read More about Exploring the responses of smallscale poultry keepers to avian influenza regulations and guidance in the United Kingdom, with recommendations for improved biosecurity messaging.

Lack of detection of SARS-CoV-2 in Wildlife from Kerala, India in 2020-21 (2023)
Preprint / Working Paper
Zachariah, A., Krishnankutty, S. P., Manazhi, J., Omanakuttan, V., Santosh, S., Blanchard, A. M., & Tarlinton, R. E. (2023). Lack of detection of SARS-CoV-2 in Wildlife from Kerala, India in 2020-21

Spill over of SARs-CoV-2 into a variety of wild and domestic animals has been an ongoing feature of the human pandemic. The establishment of a new reservoir in white tailed deer in North America and increasing divergence of the viruses circulating in... Read More about Lack of detection of SARS-CoV-2 in Wildlife from Kerala, India in 2020-21.