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Dr RACHAEL TARLINTON's Outputs (80)

Multiple sclerosis between genetics and infections: human endogenous retroviruses in monocytes and macrophages (2015)
Journal Article
Morandi, E., Tarlinton, R., & Gran, B. (2015). Multiple sclerosis between genetics and infections: human endogenous retroviruses in monocytes and macrophages. Frontiers in Immunology, 6, https://doi.org/10.3389/fimmu.2015.00647

The etiology of multiple sclerosis (MS) is still unknown, but there is strong evidence that genetic predisposition associated with environmental factors can trigger the disease. An estimated 30 million years ago, exogenous retroviruses are thought to... Read More about Multiple sclerosis between genetics and infections: human endogenous retroviruses in monocytes and macrophages.

Longitudinal study of Asian elephants, Elephas maximus, indicates intermittent shedding of elephant endotheliotropic herpesvirus 1 during pregnancy (2015)
Journal Article
Bennett, L., Dunham, S. P., Yon, L., Chapman, S., Kenaghan, M., Purdie, L., & Tarlinton, R. E. (2015). Longitudinal study of Asian elephants, Elephas maximus, indicates intermittent shedding of elephant endotheliotropic herpesvirus 1 during pregnancy. Veterinary Record Open, 2(1), Article e000088. https://doi.org/10.1136/vetreco-2014-000088

Introduction: EEHV-1 is a viral infection of elephants that has been associated with a fatal haemorrhagic syndrome in Asian elephants. Previous studies have suggested that pregnant animals may shed more virus than non-pregnant animals.
Methods: This... Read More about Longitudinal study of Asian elephants, Elephas maximus, indicates intermittent shedding of elephant endotheliotropic herpesvirus 1 during pregnancy.

Seroprevalence of Schmallenberg virus in the United Kingdom and the Republic of Ireland: 2011-2013 (2015)
Journal Article
Tarlinton, R., King, B., O'Shea Brown, T., & Daly, J. M. (2015). Seroprevalence of Schmallenberg virus in the United Kingdom and the Republic of Ireland: 2011-2013. Veterinary Microbiology, 180(1-2), 36-40. https://doi.org/10.1016/j.vetmic.2015.07.025

© 2015 Elsevier B.V. Since its identification in late 2011, Schmallenberg virus (SBV) spread rapidly across Europe. Using archived samples from domestic ruminants collected between October 2011 and June 2013, the seroprevalence in the United Kingdom... Read More about Seroprevalence of Schmallenberg virus in the United Kingdom and the Republic of Ireland: 2011-2013.

Comparison of Schmallenberg virus antibody levels detected in milk and serum from individual cows (2015)
Journal Article
Daly, J. M., King, B., Tarlinton, R. A., Gough, K. C., Maddison, B. C., & Blowey, R. (2015). Comparison of Schmallenberg virus antibody levels detected in milk and serum from individual cows. BMC Veterinary Research, 11, Article 56. https://doi.org/10.1186/s12917-015-0365-1

© Daly et al.; licensee BioMed Central. Background: Schmallenberg virus (SBV) is a recently emerged virus of ruminants in Europe. Enzyme-linked immunosorbent assays (ELISA) are commonly used to detect SBV-specific antibodies in bulk tank milk samples... Read More about Comparison of Schmallenberg virus antibody levels detected in milk and serum from individual cows.

Multiple groups of endogenous epsilon-like retroviruses conserved across primates (2014)
Journal Article
Brown, K., Emes, R. D., & Tarlinton, R. E. (2014). Multiple groups of endogenous epsilon-like retroviruses conserved across primates. Journal of Virology, 88(21), https://doi.org/10.1128/JVI.00966-14

Several types of cancer in fish are caused by retroviruses, including those responsible for major outbreaks of disease, such as walleye dermal sarcoma virus and salmon swim bladder sarcoma virus. These viruses form a phylogenetic group often describe... Read More about Multiple groups of endogenous epsilon-like retroviruses conserved across primates.

Characterisation of the horse transcriptome from immunologically active tissues (2014)
Journal Article
Moreton, J., Malla, S., Aboobaker, A., Tarlinton, R. E., & Emes, R. D. (2014). Characterisation of the horse transcriptome from immunologically active tissues. PeerJ, 2, Article e382. https://doi.org/10.7717/peerj.382

The immune system of the horse has not been well studied, despite the fact that the horse displays several features such as sensitivity to bacterial lipopolysaccharide that make them in many ways a more suitable model of some human disorders than the... Read More about Characterisation of the horse transcriptome from immunologically active tissues.

Schmallenberg virus update (2014)
Journal Article
Tarlinton, R. (2014). Schmallenberg virus update. Cattle Practice, 22, 65

Since emerging in Europe in 2011 Schmallenberg Virus (SBV) has affected over 6000 holdings over most of the continent. The virus causes mild disease in adult ruminant animals (fever, milk drop and diarrhoea) but readily crosses the placenta of sheep,... Read More about Schmallenberg virus update.

Report of the first veterinary student support workshop (2013)
Journal Article
Kydd, J. H., Cobb, K., Davis, R., Dean, R., Drinkwater, J., Dunham, S., Flynn, R., Gray, C., Grogono-Thomas, R., Hagan, P., Jefferies, A., Jones, M., Ogden, C., Pearson, G., Robinson, N., Rutland, C., Tarlinton, R., Tötemeyer, S., Wason, J., Whittington, R., …Mossop, L. (2013). Report of the first veterinary student support workshop. Veterinary Record, 173(14), 346. https://doi.org/10.1136/vr.101782

Characterisation of a group of endogenous gammaretroviruses in the canine genome (2013)
Journal Article
Tarlinton, R. E., Barfoot, H. K., Allen, C. E., Brown, K., Gifford, R. J., & Emes, R. D. (2013). Characterisation of a group of endogenous gammaretroviruses in the canine genome. Veterinary Journal, 196(1), https://doi.org/10.1016/j.tvjl.2012.08.011

Bioinformatics were used to identify and characterise 39 pol, 34 gag and five env gammaretroviruses within the canine (Canis lupus familiaris) reference genome. These endogenous retroviruses are monophyletic to the Canidae, predate the divergence of... Read More about Characterisation of a group of endogenous gammaretroviruses in the canine genome.

The challenge of Schmallenberg virus emergence in Europe (2012)
Journal Article
Tarlinton, R., Daly, J. M., Dunham, S. P., & Kydd, J. M. (2012). The challenge of Schmallenberg virus emergence in Europe. Veterinary Journal, 194(1), 10-18. https://doi.org/10.1016/j.tvjl.2012.08.017

The large-scale outbreak of disease across Northern Europe caused by a new orthobunyavirus known as
Schmallenberg virus has caused considerable disruption to lambing and calving. Although advances in
technology and collaboration between veterinary... Read More about The challenge of Schmallenberg virus emergence in Europe.

Koala retrovirus endogenisation in action (2012)
Book Chapter
Tarlinton, R. E. (2012). Koala retrovirus endogenisation in action. In G. Witzany (Ed.), Viruses: Essential Agents of Life (283-291). Springer. https://doi.org/10.1007/978-94-007-4899-6_14

Koala retrovirus (KoRV) is a unique example of a retroviral group -currently undergoing the process of endogenisation. While endogenous retroviruses (ERVs) are ubiquitous elements in vertebrate genomes there is currently little understanding of the p... Read More about Koala retrovirus endogenisation in action.

Characterisation of retroviruses in the horse genome and their transcriptional activity via transcriptome sequencing (2012)
Journal Article
Brown, K., Moreton, J., Malla, S., Aboobaker, A. A., Emes, R. D., & Tarlinton, R. E. (2012). Characterisation of retroviruses in the horse genome and their transcriptional activity via transcriptome sequencing. Virology, 433(1), https://doi.org/10.1016/j.virol.2012.07.010

The recently released draft horse genome is incompletely characterised in terms of its repetitive
element profile. This paper presents characterisation of the endogenous retrovirus (ERVs) of the horse
genome based on a data-mining strategy using mur... Read More about Characterisation of retroviruses in the horse genome and their transcriptional activity via transcriptome sequencing.

Betaherpesvirus sequences in eastern spiny mice and Wagner's dipodils (2011)
Journal Article
Tarlinton, R. E., Tate, H. F., Mohallal, E. M., Daly, J. M., & Behnke, J. M. (2011). Betaherpesvirus sequences in eastern spiny mice and Wagner's dipodils. Journal of Wildlife Diseases, 47(4), 958-962. https://doi.org/10.7589/0090-3558-47.4.958

Eastern spiny mice (Acomys dimidiatus; also known as Sinai spiny mice) have been extensively studied in terms of the influence of parasite load on population size and reproductive fitness. The physical isolation of these rodent populations makes them... Read More about Betaherpesvirus sequences in eastern spiny mice and Wagner's dipodils.

Confidence as a barrier to the use of problem-based learning in veterinary undergraduate students (2011)
Journal Article
Tarlinton, R. E., Yon, L., Klisch, K., Tötemeyer, S., & Gough, K. C. (2011). Confidence as a barrier to the use of problem-based learning in veterinary undergraduate students. Journal of Veterinary Medical Education, 38(3), 305-310

Problem-based or case-based learning is a popular method of instruction in clinical degrees such as veterinary science, nursing, and medicine. It is difficult, however, for students to adapt to this learning method, and this difficulty has been well... Read More about Confidence as a barrier to the use of problem-based learning in veterinary undergraduate students.

Endogenous retroviruses: Biology and evolution of the endogenous koala retrovirus (2008)
Journal Article
Tarlinton, R., Meers, J., & Young, P. (2008). Endogenous retroviruses: Biology and evolution of the endogenous koala retrovirus. Cellular and Molecular Life Sciences, 65(21), 3413-3421. https://doi.org/10.1007/s00018-008-8499-y

Although endogenous retroviruses are ubiquitous features of all mammalian genomes, the process of initial germ line invasion and subsequent inactivation from a pathogenic element has not yet been observed in a wild species. Koala retrovirus (KoRV) pr... Read More about Endogenous retroviruses: Biology and evolution of the endogenous koala retrovirus.

Retroviral invasion of the koala genome (2006)
Journal Article
Tarlinton, R. E., Meers, J., & Young, P. R. (2006). Retroviral invasion of the koala genome. Nature, 442(7098), 79-81. https://doi.org/10.1038/nature04841

Endogenous retroviruses are a common ancestral feature of mammalian genomes with most having been inactivated over time through mutation and deletion. A group of more intact endogenous retroviruses are considered to have entered the genomes of some s... Read More about Retroviral invasion of the koala genome.

Real-time reverse transcriptase PCR for the endogenous koala retrovirus reveals an association between plasma viral load and neoplastic disease in koalas (2005)
Journal Article
Tarlinton, R., Meers, J., Hanger, J., & Young, P. (2005). Real-time reverse transcriptase PCR for the endogenous koala retrovirus reveals an association between plasma viral load and neoplastic disease in koalas. Journal of General Virology, 86(3), 783-787. https://doi.org/10.1099/vir.0.80547-0

Koala retrovirus (KoRV) is a newly described endogenous retrovirus and is unusual in that inserts comprise a full-length replication competent genome. As koalas are known to suffer from an extremely high incidence of leukaemia/lymphoma, the associati... Read More about Real-time reverse transcriptase PCR for the endogenous koala retrovirus reveals an association between plasma viral load and neoplastic disease in koalas.