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Outputs (9)

Transfer of thawed frozen embryo versus fresh embryo to improve the healthy baby rate in women undergoing IVF: the E-Freeze RCT (2022)
Journal Article
Maheshwari, A., Bari, V., Bell, J. L., Bhattacharya, S., Bhide, P., Bowler, U., …Troup, S. (2022). Transfer of thawed frozen embryo versus fresh embryo to improve the healthy baby rate in women undergoing IVF: the E-Freeze RCT. Health Technology Assessment, 26(25), 1-142. https://doi.org/10.3310/AEFU1104

Background Freezing all embryos, followed by thawing and transferring them into the uterine cavity at a later stage (freeze-all), instead of fresh-embryo transfer may lead to improved pregnancy rates and fewer complications during in vitro fertilisa... Read More about Transfer of thawed frozen embryo versus fresh embryo to improve the healthy baby rate in women undergoing IVF: the E-Freeze RCT.

Elective freezing of embryos versus fresh embryo transfer in IVF: a multicentre randomized controlled trial in the UK (E-Freeze) (2022)
Journal Article
Maheshwari, A., Bell, J. L., Bhide, P., Brison, D., Child, T., Chong, H. Y., …Bhattacharya, S. (2022). Elective freezing of embryos versus fresh embryo transfer in IVF: a multicentre randomized controlled trial in the UK (E-Freeze). Human Reproduction, 37(3), 476-487. https://doi.org/10.1093/humrep/deab279

STUDY QUESTION: Does a policy of elective freezing of embryos, followed by frozen embryo transfer result in a higher healthy baby rate, after first embryo transfer, when compared with the current policy of transferring fresh embryos? SUMMARY ANSWER:... Read More about Elective freezing of embryos versus fresh embryo transfer in IVF: a multicentre randomized controlled trial in the UK (E-Freeze).

Levothyroxine in women with thyroid peroxidase antibodies before conception (2019)
Journal Article
Dhillon-Smith, R. K., Middleton, L. J., Sunner, K. K., Cheed, V., Baker, K., Farrell-Carver, S., …Coomarasamy, A. (2019). Levothyroxine in women with thyroid peroxidase antibodies before conception. New England Journal of Medicine, 380(14), 1316-1325. https://doi.org/10.1056/nejmoa1812537

Background Thyroid peroxidase antibodies are associated with an increased risk of miscarriage and preterm birth, even when thyroid function is normal. Small trials indicate that the use of levothyroxine could reduce the incidence of such adverse out... Read More about Levothyroxine in women with thyroid peroxidase antibodies before conception.

Priorities for research in miscarriage: a priority setting partnership between people affected by miscarriage and professionals, following the James Lind Alliance methodology (2017)
Journal Article
Prior, M., Bagness, C., Brewin, J., Coomarasamy, A., Easthope, L., Hepworth-Jones, B., …Metcalf, L. (2017). Priorities for research in miscarriage: a priority setting partnership between people affected by miscarriage and professionals, following the James Lind Alliance methodology. BMJ Open, 7, Article e016571. https://doi.org/10.1136/bmjopen-2017-016571

Objectives: To identify and prioritise important research questions for miscarriage. Design: A priority setting partnership using prospective surveys and consensus meetings following methods advocated by the James Lind Alliance. Setting: United Kin... Read More about Priorities for research in miscarriage: a priority setting partnership between people affected by miscarriage and professionals, following the James Lind Alliance methodology.

Anxiety associated with diagnostic uncertainties in early pregnancy. (2016)
Journal Article
Richardson, A., Raine-Fenning, N., Deb, S., Campbell, B., & Vedhara, K. (in press). Anxiety associated with diagnostic uncertainties in early pregnancy. Ultrasound in Obstetrics and Gynaecology, https://doi.org/10.1002/uog.17214

Objectives: To determine anxiety levels of women presenting to Early Pregnancy Assessment Units (EPAU) with abdominal pain and/or vaginal bleeding and assess how these change over time and according to ultrasonographic diagnosis. Methods: We under... Read More about Anxiety associated with diagnostic uncertainties in early pregnancy..

Heparin for assisted reproduction (Review) (2013)
Journal Article
Akhtar, M. A., Sur, S. D., Raine-Fenning, N., Jayaprakasan, K., Thornton, J., & Quenby, S. (2013). Heparin for assisted reproduction (Review). Cochrane Library, https://doi.org/10.1002/14651858.CD009452.pub2

Abstract BACKGROUND: Heparin as an adjunct in assisted reproduction (peri-implantation heparin) is given at or after egg collection or at embryo transfer during assisted reproduction. Heparin has been advocated to improve embryo implantation and cl... Read More about Heparin for assisted reproduction (Review).

Maternal smoking during pregnancy and fetal organ growth: a magnetic resonance imaging study (2013)
Journal Article
Anblagan, D., Jones, N. W., Costigan, C., Parker, A. J., Allcock, K., Aleong, R., …Gowland, P. A. (2013). Maternal smoking during pregnancy and fetal organ growth: a magnetic resonance imaging study. PLoS ONE, 8(6), Article e67223. https://doi.org/10.1371/journal.pone.0067223

Objective: To study whether maternal cigarette smoking during pregnancy is associated with alterations in the growth of fetal lungs, kidneys, liver, brain, and placenta. Design: A case-control study, with operators performing the image analysis bli... Read More about Maternal smoking during pregnancy and fetal organ growth: a magnetic resonance imaging study.