All Outputs (18)

Improvements in Between-Vendor MRI Harmonization of Renal T2 Mapping using Stimulated Echo Compensation (2024)
Journal Article
Li, H., Daniel, A. J., Buchanan, C. E., Nery, F., Morris, D. M., Li, S., Huang, Y., Sousa, J. A., Sourbron, S., Mendichovszky, I. A., Thomas, D. L., Priest, A. N., & Francis, S. T. (2024). Improvements in Between-Vendor MRI Harmonization of Renal T2 Mapping using Stimulated Echo Compensation. Journal of Magnetic Resonance Imaging, 60(5), 2144-2155. https://doi.org/10.1002/jmri.29282

Background: T2 mapping is valuable to evaluate pathophysiology in kidney disease. However, variations in T2 relaxation time measurements across MR scanners and vendors may occur requiring additional correction. Purpose: To harmonize renal T2 measurem... Read More about Improvements in Between-Vendor MRI Harmonization of Renal T2 Mapping using Stimulated Echo Compensation.

Multiparametric Renal Magnetic Resonance Imaging for Prediction and Annual Monitoring of the Progression of Chronic Kidney Disease over Two Years (2023)
Journal Article
Buchanan, C. E., Mahmoud, H., Cox, E. F., Prestwich, B. L., Noble, R. A., Selby, N. M., Taal, M. W., & Francis, S. T. (2023). Multiparametric Renal Magnetic Resonance Imaging for Prediction and Annual Monitoring of the Progression of Chronic Kidney Disease over Two Years. Journal of Clinical Medicine, 12(23), Article 7282. https://doi.org/10.3390/jcm12237282

Background: Multiparametric renal Magnetic Resonance Imaging (MRI) provides a non-invasive method to assess kidney structure and function, but longitudinal studies are limited. Methods: A total of 22 patients with CKD category G3-4 (estimated glomeru... Read More about Multiparametric Renal Magnetic Resonance Imaging for Prediction and Annual Monitoring of the Progression of Chronic Kidney Disease over Two Years.

ISMRM Open Science Initiative for Perfusion Imaging (OSIPI): ASL pipeline inventory (2023)
Journal Article
Fan, H., Mutsaerts, H. J. M. M., Anazodo, U., Arteaga, D., Baas, K. P. A., Buchanan, C., Camargo, A., Keil, V. C., Lin, Z., Lindner, T., Hirschler, L., Hu, J., Padrela, B. E., Taghvaei, M., Thomas, D. L., Dolui, S., & Petr, J. (2024). ISMRM Open Science Initiative for Perfusion Imaging (OSIPI): ASL pipeline inventory. Magnetic Resonance in Medicine, 91(5), 1787-1802. https://doi.org/10.1002/mrm.29869

Purpose: To create an inventory of image processing pipelines of arterial spin labeling (ASL) and list their main features, and to evaluate the capability, flexibility, and ease of use of publicly available pipelines to guide novice ASL users in sele... Read More about ISMRM Open Science Initiative for Perfusion Imaging (OSIPI): ASL pipeline inventory.

Randomised trial comparing standard versus thermocontrolled haemodialysis using intradialytic cardiac, brain and renal magnetic resonance imaging (2023)
Journal Article
Gullapudi, V. R. L., Cox, E. F., Buchanan, C. E., Canaud, B., White, K., Taal, M. W., Selby, N. M., & Francis, S. T. (2024). Randomised trial comparing standard versus thermocontrolled haemodialysis using intradialytic cardiac, brain and renal magnetic resonance imaging. Nephrology Dialysis Transplantation, 39(2), 233–241. https://doi.org/10.1093/ndt/gfad150

Background
Ischaemic end-organ damage during haemodialysis (HD) is a significant problem that may be ameliorated by intradialytic cooling. A randomised trial was performed to compare standard HD (SHD; dialysate temperature 37°C) and programmed cooli... Read More about Randomised trial comparing standard versus thermocontrolled haemodialysis using intradialytic cardiac, brain and renal magnetic resonance imaging.

Automated renal segmentation in healthy and chronic kidney disease subjects using a convolutional neural network (2021)
Journal Article
Daniel, A., Buchanan, C., Allcock, T., Scerri, D., Cox, E., Prestwich, B., & Francis, S. (2021). Automated renal segmentation in healthy and chronic kidney disease subjects using a convolutional neural network. Magnetic Resonance in Medicine, 86(2), 1125-1136. https://doi.org/10.1002/mrm.28768

Purpose: Total Kidney Volume (TKV) is an important measure in renal disease detection and monitoring. We developed a fully automated method to segment the kidneys from T2-weighted magnetic resonance images (MRI) to calculate TKV of healthy control (H... Read More about Automated renal segmentation in healthy and chronic kidney disease subjects using a convolutional neural network.

Multiparametric MRI assessment of renal structure and function in acute kidney injury and renal recovery (2021)
Journal Article
Buchanan, C., Mahmoud, H., Cox, E., Noble, R., Prestwich, B., Kasmi, I., Taal, M. W., Francis, S., & Selby, N. M. (2021). Multiparametric MRI assessment of renal structure and function in acute kidney injury and renal recovery. Clinical Kidney Journal, 14(8), 1969-1976. https://doi.org/10.1093/ckj/sfaa221

Background: Acute Kidney Injury (AKI) is associated with a marked increase in mortality as well as subsequent chronic kidney disease (CKD) and end stage kidney disease. We performed multiparametric MRI with the aim of identifying potential non-invasi... Read More about Multiparametric MRI assessment of renal structure and function in acute kidney injury and renal recovery.

Circadian variation in renal blood flow and kidney function in healthy volunteers monitored using non-invasive magnetic resonance imaging (2020)
Journal Article
Eckerbom, P., Hansell, P., Cox, E., Buchanan, C., Weis, J., Palm, F., Francis, S., & Liss, P. (2020). Circadian variation in renal blood flow and kidney function in healthy volunteers monitored using non-invasive magnetic resonance imaging. AJP - Renal Physiology, 319(6), F966-F978. https://doi.org/10.1152/ajprenal.00311.2020

Circadian regulation of kidney function is involved in maintaining whole-body homeostasis and dysfunctional circadian rhythm can potentially be involved in disease development. Magnetic Resonance Imaging (MRI)provides reliable and reproducible repeti... Read More about Circadian variation in renal blood flow and kidney function in healthy volunteers monitored using non-invasive magnetic resonance imaging.

Consensus-based technical recommendations for clinical translation of renal ASL MRI (2019)
Journal Article
Nery, F., Buchanan, C. E., Harteveld, A. A., Odudu, A., Bane, O., Cox, E. F., Derlin, K., Gach, H. M., Golay, X., Gutberlet, M., Laustsen, C., Ljimani, A., Madhuranthakam, A. J., Pedrosa, I., Prasad, P. V., Robson, P. M., Sharma, K., Sourbron, S., Taso, M., Thomas, D. L., …Fernández-Seara, M. A. (2020). Consensus-based technical recommendations for clinical translation of renal ASL MRI. Magnetic Resonance Materials in Physics, Biology and Medicine, 33(1), 141-161. https://doi.org/10.1007/s10334-019-00800-z

Objectives: To develop technical recommendations for the acquisition, processing and analysis of renal ASL data in the human kidney at 1.5T and 3T field strengths that can promote standardization of renal perfusion measurements and facilitate the com... Read More about Consensus-based technical recommendations for clinical translation of renal ASL MRI.

Consensus-based technical recommendations for clinical translation of renal T1 and T2 mapping MRI (2019)
Journal Article
Semple, S. I. K., Dekkers, I. A., de Boer, A., Sharma, K., Cox, E. F., Lamb, H. J., Buckley, D. L., Bane, O., Morris, D. M., Prasad, P. V., Semple, S. I., Gillis, K. A., Hockings, P., Buchanan, C., Wolf, M., Laustsen, C., Leiner, T., Haddock, B., Hoogduin, J. M., Pullens, P., …Francis, S. (2020). Consensus-based technical recommendations for clinical translation of renal T1 and T2 mapping MRI. Magnetic Resonance Materials in Physics, Biology and Medicine, 33(1), 163-176. https://doi.org/10.1007/s10334-019-00797-5

© 2019, The Author(s). To develop technical recommendations on the acquisition and post-processing of renal longitudinal (T1) and transverse (T2) relaxation time mapping. A multidisciplinary panel consisting of 18 experts in the field of renal T1 and... Read More about Consensus-based technical recommendations for clinical translation of renal T1 and T2 mapping MRI.

A randomized, controlled, double-blind crossover study on the effects of isoeffective and isovolumetric intravenous crystalloid and gelatin on blood volume, and renal and cardiac hemodynamics (2019)
Journal Article
Bradley, C. R., Bragg, D. D., Cox, E. F., El-Sharkawy, A. M., Buchanan, C. E., Chowdhury, A. H., Macdonald, I. A., Francis, S. T., & Lobo, D. N. (2020). A randomized, controlled, double-blind crossover study on the effects of isoeffective and isovolumetric intravenous crystalloid and gelatin on blood volume, and renal and cardiac hemodynamics. Clinical Nutrition, 39(7), 2070-2079. https://doi.org/10.1016/j.clnu.2019.09.011

Background & aims
Blood volume expanding properties of colloids are superior to crystalloids. In addition to oncotic/osmotic properties, the electrolyte composition of infusions may have important effects on visceral perfusion, with infusions contai... Read More about A randomized, controlled, double-blind crossover study on the effects of isoeffective and isovolumetric intravenous crystalloid and gelatin on blood volume, and renal and cardiac hemodynamics.

Quantitative assessment of renal structural and functional changes in chronic kidney disease using multi-parametric magnetic resonance imaging (2019)
Journal Article
Buchanan, C. E., Mahmoud, H., Cox, E. F., McCulloch, T., Prestwich, B. L., Taal, M. W., Selby, N. M., & Francis, S. T. (2020). Quantitative assessment of renal structural and functional changes in chronic kidney disease using multi-parametric magnetic resonance imaging. Nephrology Dialysis Transplantation, 35(6), 955-964. https://doi.org/10.1093/ndt/gfz129

BACKGROUND:
Multi-parametric magnetic resonance imaging (MRI) provides the potential for a more comprehensive non-invasive assessment of organ structure and function than individual MRI measures, but has not previously been comprehensively evaluated... Read More about Quantitative assessment of renal structural and functional changes in chronic kidney disease using multi-parametric magnetic resonance imaging.

Arterial spin labelling MRI to measure renal perfusion: a systematic review and statement paper (2018)
Journal Article
Odudu, A., Nery, F., Harteveld, A. A., Evans, R. G., Pendse, D., Buchanan, C. E., Francis, S. T., & Fernandez-Seara, M. A. (2018). Arterial spin labelling MRI to measure renal perfusion: a systematic review and statement paper. Nephrology Dialysis Transplantation, 33(Issue suppl_2), ii15-ii21. https://doi.org/10.1093/ndt/gfy180

Renal perfusion provides the driving pressure for glomerular filtration and delivers the oxygen and nutrients to fuel solute reabsorption. Renal ischaemia is a major mechanism in acute kidney injury and may promote the progression of chronic kidney d... Read More about Arterial spin labelling MRI to measure renal perfusion: a systematic review and statement paper.

Evaluation of 2D Imaging Schemes for Pulsed Arterial Spin Labeling of the Human Kidney Cortex (2018)
Journal Article
Buchanan, C. E., Cox, E. F., & Francis, S. T. (2018). Evaluation of 2D Imaging Schemes for Pulsed Arterial Spin Labeling of the Human Kidney Cortex. Diagnostics, 8(3), Article 43. https://doi.org/10.3390/diagnostics8030043

Purpose
A number of imaging readout schemes have been proposed for renal arterial spin labelling (ASL) to quantify kidney cortex perfusion, including gradient echo based methods of balanced fast field echo (bFFE) and gradient-echo echo-planar imagi... Read More about Evaluation of 2D Imaging Schemes for Pulsed Arterial Spin Labeling of the Human Kidney Cortex.

Multiparametric renal magnetic resonance imaging: validation, interventions, and alterations in chronic kidney disease (2017)
Journal Article
Cox, E. F., Buchanan, C. E., Bradley, C. R., Prestwich, B., Mahmoud, H., Taal, M., Selby, N. M., & Francis, S. T. (2017). Multiparametric renal magnetic resonance imaging: validation, interventions, and alterations in chronic kidney disease. Frontiers in Physiology, 8, Article 696. https://doi.org/10.3389/fphys.2017.00696

Background: This paper outlines a multiparametric renal MRI acquisition and analysis protocol to allow non-invasive assessment of hemodynamics (renal artery blood flow and perfusion), oxygenation (BOLD T2*), and microstructure (diffusion, T1 mapping)... Read More about Multiparametric renal magnetic resonance imaging: validation, interventions, and alterations in chronic kidney disease.

Sodium MRI: a new frontier in imaging in nephrology (2017)
Journal Article
Francis, S. T., Buchanan, C., Prestwich, B., & Taal, M. W. (2017). Sodium MRI: a new frontier in imaging in nephrology. Current Opinion in Nephrology and Hypertension, 26(6), 435-441. https://doi.org/10.1097/MNH.0000000000000370

Purpose of review

This review focuses on the recent technological advances in quantitative sodium (23Na) MRI to provide a noninvasive measure of tissue viability for use in clinical studies of patients with kidney disease. 23Na MRI is the only non... Read More about Sodium MRI: a new frontier in imaging in nephrology.

Endotoxemia in peritoneal dialysis patients: a pilot study to examine the role of intestinal perfusion and congestion (2017)
Journal Article
Grant, C., Harrison, L., Hoad, C., Marciani, L., Cox, E., Buchanan, C., Costigan, C., Francis, S., Lai, K.-B., Szeto, C.-C., Gowland, P., & McIntyre, C. (2017). Endotoxemia in peritoneal dialysis patients: a pilot study to examine the role of intestinal perfusion and congestion. Peritoneal Dialysis International, 37(1), 111-115. https://doi.org/10.3747/pdi.2016.00079

Endotoxemia is common in advanced chronic kidney disease and is particularly severe in those receiving dialysis. In hemodialysis patients, translocation from the bowel occurs as a consequence of recurrent circulatory stress leading to a reduction in... Read More about Endotoxemia in peritoneal dialysis patients: a pilot study to examine the role of intestinal perfusion and congestion.

Intradialytic Cardiac Magnetic Resonance Imaging to Assess Cardiovascular Responses in a Short-Term Trial of Hemodiafiltration and Hemodialysis (2016)
Journal Article
Buchanan, C., Mohammed, A., Cox, E., Köhler, K., Canaud, B., Taal, M. W., Selby, N. M., Francis, S. T., & McIntyre, C. W. (2017). Intradialytic Cardiac Magnetic Resonance Imaging to Assess Cardiovascular Responses in a Short-Term Trial of Hemodiafiltration and Hemodialysis. Journal of the American Society of Nephrology, 28(4), 1269-1277. https://doi.org/10.1681/ASN.2016060686

Hemodynamic stress during hemodialysis (HD) results in recurrent segmental ischemic injury (myocardial stunning) that drives cumulative cardiac damage. We performed a fully comprehensive study of the cardiovascular effect of dialysis sessions using i... Read More about Intradialytic Cardiac Magnetic Resonance Imaging to Assess Cardiovascular Responses in a Short-Term Trial of Hemodiafiltration and Hemodialysis.

Imaging the kidney using magnetic resonance techniques: structure to function (2016)
Journal Article
Mahmoud, H., Buchanan, C., Francis, S. T., & Selby, N. M. (2016). Imaging the kidney using magnetic resonance techniques: structure to function. Current Opinion in Nephrology and Hypertension, 25(6), https://doi.org/10.1097/MNH.0000000000000266

Purpose of review
Magnetic resonance imaging (MRI) offers the possibility to non-invasively assess both the structure and function of the kidney in a single MR scan session. This review summarises recent advancements in functional renal MRI techniqu... Read More about Imaging the kidney using magnetic resonance techniques: structure to function.