2023 EULAR recommendations on imaging in diagnosis and management of crystal-induced arthropathies in clinical practice

Mandl, Peter; D'Agostino, Maria Antonietta; Navarro-Compán, Victoria; Geßl, Irina; Sakellariou, Garifallia; Abhishek, Abhishek; Becce, Fabio; Dalbeth, Nicola; Ea, Hang-Korng; Filippucci, Emilio; Hammer, Hilde Berner; Iagnocco, Annamaria; de Thurah, Annette; Naredo, Esperanza; Ottaviani, Sebastien; Pascart, Tristan; Pérez-Ruiz, Fernando; Pitsillidou, Irene A; Proft, Fabian; Rech, Juergen; Schmidt, Wolfgang A; Sconfienza, Luca Maria; Terslev, Lene; Wildner, Brigitte; Zufferey, Pascal; Filippou, Georgios

Abstract

Objective: To formulate evidence-based recommendations and overarching principles on the use of imaging in the clinical management of crystal-induced arthropathies (CiAs). Methods: An international task force of 25 rheumatologists, radiologists, methodologists, healthcare professionals and patient research partners from 11 countries was formed according to the EULAR standard operating procedures. Fourteen key questions on the role of imaging in the most common forms of CiA were generated. The CiA assessed included gout, calcium pyrophosphate deposition disease and basic calcium phosphate deposition disease. Imaging modalities included conventional radiography, ultrasound, CT and MRI. Experts applied research evidence obtained from four systematic literature reviews using MEDLINE, EMBASE and CENTRAL. Task force members provided level of agreement (LoA) anonymously by using a Numerical Rating Scale from 0 to 10. Results: Five overarching principles and 10 recommendations were developed encompassing the role of imaging in various aspects of patient management: making a diagnosis of CiA, monitoring inflammation and damage, predicting outcome, response to treatment, guided interventions and patient education. Overall, the LoA for the recommendations was high (8.46-9.92). Conclusions: These are the first recommendations that encompass the major forms of CiA and guide the use of common imaging modalities in this disease group in clinical practice.

Citation

Mandl, P., D'Agostino, M. A., Navarro-Compán, V., Geßl, I., Sakellariou, G., Abhishek, A., …Filippou, G. (2024). 2023 EULAR recommendations on imaging in diagnosis and management of crystal-induced arthropathies in clinical practice. Annals of the Rheumatic Diseases, 83, 752-759. https://doi.org/10.1136/ard-2023-224771

• Journal Article Type: Article
• Acceptance Date: Jan 30, 2024
• Online Publication Date: Feb 6, 2024
• Publication Date: 2024-06
• Deposit Date: Apr 16, 2024
• Publicly Available Date: Apr 16, 2024
• Journal: Annals of the Rheumatic Diseases
• Print ISSN: 0003-4967
• Electronic ISSN: 1468-2060
• Publisher: BMJ Publishing Group
• Peer Reviewed: Peer Reviewed
• Volume: 83
• Pages: 752-759
• DOI: https://doi.org/10.1136/ard-2023-224771
• Keywords: Ultrasonography, Magnetic Resonance Imaging, Crystal arthropathies
• Public URL: https://nottingham-repository.worktribe.com/output/31880935
• Publisher URL: https://ard.bmj.com/content/early/2024/02/05/ard-2023-224771