JNK signalling modulates intestinal homeostasis and tumourigenesis in mice
(2009)
Journal Article
Sancho, R., Nateri, A. S., De Vinuesa, A. G., Aguilera, C., Nye, E., Spencer-Dene, B., & Behrens, A. (2009). JNK signalling modulates intestinal homeostasis and tumourigenesis in mice. EMBO Journal, 28(13), 1843-1854. https://doi.org/10.1038/emboj.2009.153
Wnt signalling is a crucial signalling pathway controlling intestinal homeostasis and cancer. We show here that the JNK MAP kinase pathway and one of its most important substrates, the AP-1 transcription factor c-Jun, modulates Wnt signalling strengt... Read More about JNK signalling modulates intestinal homeostasis and tumourigenesis in mice.