Outputs (359)

Association of CYP2C19 Loss-of-Function Metabolizer Status With Stroke Risk Among Chinese Patients Treated With Ticagrelor-Aspirin vs Clopidogrel-Aspirin: A Prespecified Secondary Analysis of a Randomized Clinical Trial. (2023)
Journal Article
Xie, X., Johnston, S. C., Wang, A., Xu, Q., Bath, P. M., Pan, Y., …Wang, Y. (2023). Association of CYP2C19 Loss-of-Function Metabolizer Status With Stroke Risk Among Chinese Patients Treated With Ticagrelor-Aspirin vs Clopidogrel-Aspirin: A Prespecified Secondary Analysis of a Randomized Clinical Trial. JAMA Network Open, 6(6), Article e2317037. https://doi.org/10.1001/jamanetworkopen.2023.17037

Importance: The Clopidogrel With Aspirin in High-Risk Patients With Acute Nondisabling Cerebrovascular Events II (CHANCE-2) trial showed that ticagrelor-aspirin combination therapy reduced the risk of stroke compared with a clopidogrel-aspirin combi... Read More about Association of CYP2C19 Loss-of-Function Metabolizer Status With Stroke Risk Among Chinese Patients Treated With Ticagrelor-Aspirin vs Clopidogrel-Aspirin: A Prespecified Secondary Analysis of a Randomized Clinical Trial..

Care for older forensic mental health patients: A consensus guidance document (2023)
Journal Article
Tomlin, J., Walker, K., Yates, J., Dening, T., Goethals, K., Völlm, B., & Griffiths, C. (2023). Care for older forensic mental health patients: A consensus guidance document. European Psychiatry, 66(1), Article e44. https://doi.org/10.1192/j.eurpsy.2023.2413

Background
It is important to investigate the needs, experiences, and outcomes of older forensic mental health inpatients. In this consensus document, we offer practitioners working with older forensic inpatients recommendations to meet the unique o... Read More about Care for older forensic mental health patients: A consensus guidance document.

The association between the Multiple Sclerosis Screening Questionnaire and objective measures of cognition: a systematic literature review and meta-analysis (2023)
Journal Article
Tunmore, J., Kontou, E., Moghaddam, N., Hufton, L., & Das Nair, R. (2023). The association between the Multiple Sclerosis Screening Questionnaire and objective measures of cognition: a systematic literature review and meta-analysis. Journal of Clinical and Experimental Neuropsychology, 45(2), 197-217. https://doi.org/10.1080/13803395.2023.2213847

Introduction
The Multiple Sclerosis Screening Questionnaire (MSNQ) is a self-report measure used to assess cognitive difficulties in people with Multiple Sclerosis (PwMS). The aim of this systematic review was to determine the associations between t... Read More about The association between the Multiple Sclerosis Screening Questionnaire and objective measures of cognition: a systematic literature review and meta-analysis.

Development of cancer surveillance guidelines in ataxia telangiectasia: A Delphi‐based consensus survey of international experts (2023)
Journal Article
Neves, R., DeDiosPerez, B., Panek, R., Jagani, S., Wilne, S., Mahendra Bhatt, J., …Dineen, R. A. (2023). Development of cancer surveillance guidelines in ataxia telangiectasia: A Delphi‐based consensus survey of international experts. Cancer Medicine, 12(13), 14663-14673. https://doi.org/10.1002/cam4.6075

Background/Objectives: Ataxia telangiectasia (A‐T) is a multiorgan disorder with increased vulnerability to cancer. Despite this increased cancer risk, there are no widely accepted guidelines for cancer surveillance in people affected by A‐T. We aime... Read More about Development of cancer surveillance guidelines in ataxia telangiectasia: A Delphi‐based consensus survey of international experts.

Remote administration of ADHD-sensitive cognitive tasks: a pilot study (2023)
Journal Article
Sun, S., Denyer, H., Sankesara, H., Deng, Q., Ranjan, Y., Conde, P., …Kuntsi, J. (2023). Remote administration of ADHD-sensitive cognitive tasks: a pilot study. Journal of Attention Disorders, 27(9), 1040-1050. https://doi.org/10.1177/10870547231172

Objective:
We assessed the feasibility and validity of remote researcher-led administration and self-administration of modified versions of two cognitive tasks sensitive to ADHD, a four-choice reaction time task (Fast task) and a combined Continuous... Read More about Remote administration of ADHD-sensitive cognitive tasks: a pilot study.

Training for line managers should focus on primary prevention of mental ill-health at work (2023)
Journal Article
Blake, H., Hassard, J., Bartle, C., & Thomson, L. (2023). Training for line managers should focus on primary prevention of mental ill-health at work. Perspectives in Public Health, 143(3), 124-125. https://doi.org/10.1177/17579139231157528

Isosorbide Mononitrate and Cilostazol Treatment in Patients With Symptomatic Cerebral Small Vessel Disease: The Lacunar Intervention Trial-2 (LACI-2) Randomized Clinical Trial (2023)
Journal Article
Wardlaw, J. M., Woodhouse, L. J., Mhlanga, I. I., Oatey, K., Heye, A. K., Bamford, J., …Bath, P. M. (2023). Isosorbide Mononitrate and Cilostazol Treatment in Patients With Symptomatic Cerebral Small Vessel Disease: The Lacunar Intervention Trial-2 (LACI-2) Randomized Clinical Trial. JAMA Neurology, 80(7), 682-692. https://doi.org/10.1001/jamaneurol.2023.1526

Importance Cerebral small vessel disease (cSVD) is a common cause of stroke (lacunar stroke), is the most common cause of vascular cognitive impairment, and impairs mobility and mood but has no specific treatment.

Objective To test the feasibili... Read More about Isosorbide Mononitrate and Cilostazol Treatment in Patients With Symptomatic Cerebral Small Vessel Disease: The Lacunar Intervention Trial-2 (LACI-2) Randomized Clinical Trial.

Pregnancy-related discrimination and expectant workers' psychological well-being and work engagement: understanding the moderating role of job resources (2023)
Journal Article
Hassard, J., Wang, W., Delic, L., Gruzdyte, I., Dale-Hewitt, V., & Thomson, L. (2023). Pregnancy-related discrimination and expectant workers' psychological well-being and work engagement: understanding the moderating role of job resources. International Journal of Workplace Health Management, 16(2/3), 188-204. https://doi.org/10.1108/IJWHM-01-2022-0005

Purpose: In this paper, the authors apply the Job Demand-Resource Model to investigate the association between pregnancy-related discrimination (conceptualised as a job demand) and expectant workers' psychological well-being and work engagement, and... Read More about Pregnancy-related discrimination and expectant workers' psychological well-being and work engagement: understanding the moderating role of job resources.

Real-world annualized relapse rates from contemporary multiple sclerosis clinics in the UK: a retrospective multicentre cohort study (2023)
Journal Article
Papathanasiou, A., Hibbert, A., Tallantyre, E., Harding, K., Selvam, A. P., Morgan, M., …Evangelou, N. (2023). Real-world annualized relapse rates from contemporary multiple sclerosis clinics in the UK: a retrospective multicentre cohort study. Neurological Sciences, 44(10), 3629-3635. https://doi.org/10.1007/s10072-023-06838-1

Background: Annualized relapse rate (ARR) is used as an outcome measure in multiple sclerosis (MS) clinical trials. Previous studies demonstrated that ARR has reduced in placebo groups between 1990 and 2012. This study aimed to estimate real-world AR... Read More about Real-world annualized relapse rates from contemporary multiple sclerosis clinics in the UK: a retrospective multicentre cohort study.

Study protocol for the use of time series forecasting and risk analyses to investigate the effect of the COVID-19 pandemic on hospital admissions associated with new-onset disability and frailty in a national, linked electronic health data setting (2023)
Journal Article
Thomas, S., Machuel, P., Foubert, J., Nafilyan, V., Bannister, N., Colvin, H., …Gordon, A. (2023). Study protocol for the use of time series forecasting and risk analyses to investigate the effect of the COVID-19 pandemic on hospital admissions associated with new-onset disability and frailty in a national, linked electronic health data setting. BMJ Open, 13(5), Article e067786. https://doi.org/10.1136/bmjopen-2022-067786

INTRODUCTION: Older people were at particular risk of morbidity and mortality during COVID-19. Consequently, they experienced formal (externally imposed) and informal (self-imposed) periods of social isolation and quarantine. This is hypothesised to... Read More about Study protocol for the use of time series forecasting and risk analyses to investigate the effect of the COVID-19 pandemic on hospital admissions associated with new-onset disability and frailty in a national, linked electronic health data setting.