Outputs (21)

Convergent genetic and expression data implicate immunity in Alzheimer's disease (2014)
Journal Article
Bossù, P., Tsuang, D. W., Lleò, A., Wallon, D., Todd, S., Dufouil, C., …Holmans, P. (2015). Convergent genetic and expression data implicate immunity in Alzheimer's disease. Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 11(6), 658-671. https://doi.org/10.1016/j.jalz.2014.05.1757

© 2015, Elsevier Inc. All rights reserved.

Background:

Late-onset Alzheimer's disease (AD) is heritable with 20 genes showing genome-wide association in the International Genomics of Alzheimer's Project (IGAP). To identify the biology underly... Read More about Convergent genetic and expression data implicate immunity in Alzheimer's disease.

Possible mechanism behind the hard-to-swallow property of oil seed pastes (2014)
Journal Article
Rosenthal, A. J., & Yilmaz, S. (2015). Possible mechanism behind the hard-to-swallow property of oil seed pastes. International Journal of Food Properties, 18(9), https://doi.org/10.1080/10942912.2013.862633

Roasted and crushed oil-rich seeds, such as sesame paste and peanut butter, both share a common structure and elicit an apparent sensation of thickening in the mouth. Working with sesame paste, as an example, the force needed to compress sesame paste... Read More about Possible mechanism behind the hard-to-swallow property of oil seed pastes.

Phenotypic variation in oronasal perception and the relative effects of PROP and Thermal Taster Status (2014)
Journal Article
Yang, Q., Hollowood, T. A., & Hort, J. (2014). Phenotypic variation in oronasal perception and the relative effects of PROP and Thermal Taster Status. Food Quality and Preference, 38, https://doi.org/10.1016/j.foodqual.2014.05.013

Individual variation in taste perception has long been investigated, particular in relation to PROP taster status (PTS). Recently, a new marker has been identified, Thermal Taster Status (TTS), whereby individuals are categorised as thermal tasters (... Read More about Phenotypic variation in oronasal perception and the relative effects of PROP and Thermal Taster Status.

Amniotic fluid phthalate levels and male fetal gonad function (2014)
Journal Article
Jensen, M. S., Anand-Ivell, R., Nørgaard-Pedersen, B., Jönsson, B. A., Bonde, J. P., Hougaard, D. M., …Toft, G. (2015). Amniotic fluid phthalate levels and male fetal gonad function. Epidemiology, 26(1), 91-99. https://doi.org/10.1097/EDE.0000000000000198

Background: Prenatal exposure to phthalates may pose a threat to human male reproduction. However, additional knowledge about the in vivo effect in humans is needed, and reported associations with genital abnormalities are inconclusive. We aimed to s... Read More about Amniotic fluid phthalate levels and male fetal gonad function.

Use of humanised rat basophilic leukaemia cell line RSATL8 for the assessment of allergenicity of Schistosoma mansoni proteins (2014)
Journal Article

Background

Parasite-specific IgE is thought to correlate with protection against Schistosoma mansoni infection or re-infection. Only a few molecular targets of the IgE response in S. mansoni infection have been characterised. A better insight into... Read More about Use of humanised rat basophilic leukaemia cell line RSATL8 for the assessment of allergenicity of Schistosoma mansoni proteins.

Characterisation of a recombinant β-xylosidase (xylA) from Aspergillus oryzae expressed in Pichia pastoris (2014)
Journal Article
Kirikyali, N., Wood, J., & Connerton, I. F. (2014). Characterisation of a recombinant β-xylosidase (xylA) from Aspergillus oryzae expressed in Pichia pastoris. AMB Express, 4(68), https://doi.org/10.1186/s13568-014-0068-1

β-xylosidases catalyse the hydrolysis of short chain xylooligosaccharides from their non-reducing ends into xylose. In this study we report the heterologous expression of Aspergillus oryzae β-xylosidase (XylA) in Pichia pastoris under the control of... Read More about Characterisation of a recombinant β-xylosidase (xylA) from Aspergillus oryzae expressed in Pichia pastoris.

Cryptorchidism in the orl rat is associated with muscle patterning defects in the fetal gubernaculum and altered hormonal signaling (2014)
Journal Article

Effect of granule organisation on the behaviour of starches in the NMMO (N-methyl morpholine N-oxide) solvent system (2014)
Journal Article
Koganti, N., Mitchell, J., MacNaughtan, W., Hill, S., & Foster, T. (2015). Effect of granule organisation on the behaviour of starches in the NMMO (N-methyl morpholine N-oxide) solvent system. Carbohydrate Polymers, 116, 103-110. https://doi.org/10.1016/j.carbpol.2014.06.060

The response of starches of different botanical origin to heating in 78% N-methyl morpholine N-oxide (NMMO) is compared with their behaviour in water. For all starches studied an exothermic transition is obtained in the NMMO system rather than the en... Read More about Effect of granule organisation on the behaviour of starches in the NMMO (N-methyl morpholine N-oxide) solvent system.

Genetic diversity of porcine group A rotavirus strains in the UK (2014)
Journal Article
Chandler-Bostock, R., Hancox, L. R., Nawaz, S., Watts, O., Iturriza-Gomara, M., & Mellits, K. M. (2014). Genetic diversity of porcine group A rotavirus strains in the UK. Veterinary Microbiology, 173(1-2), https://doi.org/10.1016/j.vetmic.2014.06.030

Rotavirus is endemic in pig farms where it causes a loss in production. This study is the first to characterise porcine rotavirus circulating in UK pigs. Samples from diarrheic pigs with rotavirus enteritis obtained between 2010 and 2012 were genotyp... Read More about Genetic diversity of porcine group A rotavirus strains in the UK.

Interactions between cellulose ethers and a bile salt in the control of lipid digestion of lipid-based systems (2014)
Journal Article
Torcello-Gómez, A., & Foster, T. (2014). Interactions between cellulose ethers and a bile salt in the control of lipid digestion of lipid-based systems. Carbohydrate Polymers, 113, https://doi.org/10.1016/j.carbpol.2014.06.070

In order to gain new insights into the potential of specific dietary fibres to control lipid digestion, the goal of this work is to study the main interactions between commercial cellulose ethers, as dietary fibre, and a bile salt, as an important du... Read More about Interactions between cellulose ethers and a bile salt in the control of lipid digestion of lipid-based systems.