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Outputs (327)

Cardiovascular risk prediction using physical performance measures in COPD: results from a multicentre observational study (2020)
Journal Article
Fermont, J. M., Fisk, M., Bolton, C. E., MacNee, W., Cockcroft, J. R., Fuld, J., …Wilkinson, I. B. (2020). Cardiovascular risk prediction using physical performance measures in COPD: results from a multicentre observational study. BMJ Open, 10(12), Article e038360. https://doi.org/10.1136/bmjopen-2020-038360

Objectives Although cardiovascular disease (CVD) is a common comorbidity associated with chronic obstructive pulmonary disease (COPD), it is unknown how to improve prediction of cardiovascular (CV) risk in individuals with COPD. Traditional CV risk s... Read More about Cardiovascular risk prediction using physical performance measures in COPD: results from a multicentre observational study.

Risk of incident dementia and cognitive impairment in patients with chronic obstructive pulmonary disease (COPD): A large UK population-based study (2020)
Journal Article
Siraj, R., McKeever, T., Gibson, J., Gordon, A., & Bolton, C. (2021). Risk of incident dementia and cognitive impairment in patients with chronic obstructive pulmonary disease (COPD): A large UK population-based study. Respiratory Medicine, 177, Article 106288. https://doi.org/10.1016/j.rmed.2020.106288

Background: Although cognitive impairment and dementia are common comorbidities in patients with chronic obstructive pulmonary disease (COPD), estimates of incidence following a diagnosis of COPD are inconclusive. Objective: To determine the incidenc... Read More about Risk of incident dementia and cognitive impairment in patients with chronic obstructive pulmonary disease (COPD): A large UK population-based study.

Machine learning can predict disease manifestations and outcomes in lymphangioleiomyomatosis (2020)
Journal Article
Chernbumroong, S., Johnson, J., Gupta, N., Miller, S., Mccormack, F. X., Garibaldi, J. M., & Johnson, S. R. (2021). Machine learning can predict disease manifestations and outcomes in lymphangioleiomyomatosis. European Respiratory Journal, 57(6), Article 2003036. https://doi.org/10.1183/13993003.03036-2020

Background: Lymphangioleiomyomatosis (LAM) is a rare multisystem disease with variable clinical manifestations and differing rates of progression that make management decisions and giving prognostic advice difficult. We used machine learning to ident... Read More about Machine learning can predict disease manifestations and outcomes in lymphangioleiomyomatosis.

British Thoracic Society survey of rehabilitation to support recovery of the post-COVID- 19 population (2020)
Journal Article
Singh, S. J., Barradell, A. C., Greening, N. J., Bolton, C., Jenkins, G., Preston, L., & Hurst, J. R. (2020). British Thoracic Society survey of rehabilitation to support recovery of the post-COVID- 19 population. BMJ Open, 10(12), Article e040213. https://doi.org/10.1136/bmjopen-2020-040213

Objective A proportion of those recovering from COVID-19 are likely to have significant and ongoing symptoms, functional impairment and psychological disturbances. There is an immediate need to develop a safe and efficient discharge process and recov... Read More about British Thoracic Society survey of rehabilitation to support recovery of the post-COVID- 19 population.

Imaging Sodium Dendrite Growth in All‐Solid‐State Sodium Batteries using 23Na T2‐weighted MRI (2020)
Journal Article
Rees, G. J., Spencer Jolly, D., Ning, Z., Marrow, T. J., Pavlovskaya, G., & Bruce, P. G. (2021). Imaging Sodium Dendrite Growth in All‐Solid‐State Sodium Batteries using 23Na T2‐weighted MRI. Angewandte Chemie, 133(4), 2138-2143. https://doi.org/10.1002/ange.202013066

Two‐dimensional, Knight‐shifted, T2‐contrasted 23Na magnetic resonance imaging of an all‐solid‐state cell with Na electrode and a ceramic electrolyte is employed to directly observe Na microstructural growth. A spalling dendritic morphology is observ... Read More about Imaging Sodium Dendrite Growth in All‐Solid‐State Sodium Batteries using 23Na T2‐weighted MRI.

Incidence of osteoporosis and fragility fractures in asthma: a UK population-based matched cohort study (2020)
Journal Article
Chalitsios, C. V., McKeever, T. M., & Shaw, D. E. (2020). Incidence of osteoporosis and fragility fractures in asthma: a UK population-based matched cohort study. European Respiratory Journal, 56(Suppl. 64), Article 1427. https://doi.org/10.1183/13993003.congress-2020.1427

Background: Osteoporosis and fragility fractures (FF) are associated with corticosteroids which are the mainstay treatment for asthma; however, these bone comorbidities within asthma need to be better described.

Methods: A matched cohort study was... Read More about Incidence of osteoporosis and fragility fractures in asthma: a UK population-based matched cohort study.

Effectiveness of the 23-valent pneumococcal polysaccharide vaccine against vaccine serotype pneumococcal pneumonia in adults: a case-control test-negative design study (2020)
Journal Article
Lawrence, H., Pick, H., Baskaran, V., Daniel, P., Rodrigo, C., Ashton, D., …Lim, W. S. (2020). Effectiveness of the 23-valent pneumococcal polysaccharide vaccine against vaccine serotype pneumococcal pneumonia in adults: a case-control test-negative design study. PLoS Medicine, 17(10), Article e1003326. https://doi.org/10.1371/journal.pmed.1003326

Background: Vaccination with the 23-valent pneumococcal polysaccharide vaccine (PPV23) is available in the UK to adults aged 65 years or over and those in defined clinical risk groups. We evaluated the vaccine effectiveness (VE) of PPV23 against vac... Read More about Effectiveness of the 23-valent pneumococcal polysaccharide vaccine against vaccine serotype pneumococcal pneumonia in adults: a case-control test-negative design study.

Risk of osteoporosis and fragility fractures in asthma due to oral and inhaled corticosteroids: two population-based nested case-control studies (2020)
Journal Article
Chalitsios, C. V., Shaw, D. E., & McKeever, T. M. (2020). Risk of osteoporosis and fragility fractures in asthma due to oral and inhaled corticosteroids: two population-based nested case-control studies. Thorax, 76(1), 21-28. https://doi.org/10.1136/thoraxjnl-2020-215664

© Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ. Background Inhaled (ICS) and oral (OCS) corticosteroids are used widely in asthma; however, the risk of osteoporosis and fragility fracture (... Read More about Risk of osteoporosis and fragility fractures in asthma due to oral and inhaled corticosteroids: two population-based nested case-control studies.

Predominant DNMT and TET mediate effects of allergen on the human bronchial epithelium in a controlled air pollution exposure study (2020)
Journal Article
Li, H., Ryu, M. H., Rider, C. F., Tse, W., Clifford, R. L., Aristizabal, M. J., …Carlsten, C. (2021). Predominant DNMT and TET mediate effects of allergen on the human bronchial epithelium in a controlled air pollution exposure study. Journal of Allergy and Clinical Immunology, 147(5), 1671-1682. https://doi.org/10.1016/j.jaci.2020.08.044

Background

Epidemiological data show that traffic-related air pollution contributes to the increasing prevalence and severity of asthma. DNA methylation (DNAm) changes may elucidate adverse health effects of environmental exposures.

Objectives... Read More about Predominant DNMT and TET mediate effects of allergen on the human bronchial epithelium in a controlled air pollution exposure study.