Outputs (3)

Investigating lung responses with functional hyperpolarized xenon-129 MRI in an ex vivo rat model of asthma (2015)
Journal Article
Lilburn, D. M., Tatler, A. L., Six, J. S., Lesbats, C., Habgood, A., Porte, J., …Meersmann, T. (2015). Investigating lung responses with functional hyperpolarized xenon-129 MRI in an ex vivo rat model of asthma. Magnetic Resonance in Medicine, 76(4), 1224-1235. https://doi.org/10.1002/mrm.26003

© 2015 The Authors. Wiley Periodicals, Inc. Purpose: Asthma is a disease of increasing worldwide importance that calls for new investigative methods. Ex vivo lung tissue is being increasingly used to study functional respiratory parameters independen... Read More about Investigating lung responses with functional hyperpolarized xenon-129 MRI in an ex vivo rat model of asthma.

Molecular sensing with hyperpolarized 129Xe using switchable chemical exchange relaxation transfer (2015)
Journal Article
Zamberlan, F., Lesbats, C., Rogers, N. J., Krupa, J. L., Pavlovskaya, G. E., Thomas, N. R., …Meersmann, T. (2015). Molecular sensing with hyperpolarized 129Xe using switchable chemical exchange relaxation transfer. ChemPhysChem, 16(11), https://doi.org/10.1002/cphc.201500367

A new approach for hyperpolarized 129Xe molecular sensors is explored using paramagnetic relaxation agents that can be deactivated upon chemical or enzymatic reaction with an analyte. Cryptophane encapsulated 129Xe within the vicinity of the paramagn... Read More about Molecular sensing with hyperpolarized 129Xe using switchable chemical exchange relaxation transfer.

Hyperpolarized 83Kr magnetic resonance imaging of alveolar degradation in a rat model of emphysema (2015)
Journal Article
Lilburn, D. M., Lesbats, C., Six, J. S., Dubuis, E., Yew-Booth, L., Shaw, D. E., …Meersmann, T. (2015). Hyperpolarized 83Kr magnetic resonance imaging of alveolar degradation in a rat model of emphysema. Interface, 12(107), Article 20150192. https://doi.org/10.1098/rsif.2015.0192

© 2015 The Authors. Hyperpolarized 83Kr surface quadrupolar relaxation (SQUARE) generates MRI contrast that was previously shown to correlate with surface-to-volume ratios in porous model surface systems. The underlying physics of SQUARE contrast is... Read More about Hyperpolarized 83Kr magnetic resonance imaging of alveolar degradation in a rat model of emphysema.