Outputs (792)

Clinicopathological and molecular significance of Sumolyation marker (ubiquitin conjugating enzyme 9 (UBC9)) expression in breast cancer of black women (2013)
Journal Article
Agboola, A. J., Musa, A., Ayoade, B., Banjo, A., Anunobi, C., Deji-Agboola, A., …Green, A. (2014). Clinicopathological and molecular significance of Sumolyation marker (ubiquitin conjugating enzyme 9 (UBC9)) expression in breast cancer of black women. Pathology - Research and Practice, 210(1), 10-17. https://doi.org/10.1016/j.prp.2013.09.011

The majority of breast cancers (BC) in Nigerian women are triple negative and show breast cancer-associated gene 1 (BRCA1) deficiency as well as the basal like phenotype, with a high mortality rate. In contrast to the well-defined predictive factors... Read More about Clinicopathological and molecular significance of Sumolyation marker (ubiquitin conjugating enzyme 9 (UBC9)) expression in breast cancer of black women.

Hoxa9 collaborates with E2A-PBX1 in mouse B cell leukemia in association with Flt3 activation and decrease of B cell gene expression (2013)
Journal Article
Hassawi, M., Shestakova, E. A., Fournier, M., Lebert-Ghali, C.-É., Vaisson, G., Frison, H., …Bijl, J. J. (2014). Hoxa9 collaborates with E2A-PBX1 in mouse B cell leukemia in association with Flt3 activation and decrease of B cell gene expression. Developmental Dynamics, 243(1), 145-158. https://doi.org/10.1002/dvdy.24056

Background: The fusion protein E2A-PBX1 induces pediatric B cell leukemia in human. Previously, we reported oncogenic interactions between homeobox (Hox) genes and E2A-PBX1 in murine T cell leukemia. A proviral insertional mutagenesis screen with our... Read More about Hoxa9 collaborates with E2A-PBX1 in mouse B cell leukemia in association with Flt3 activation and decrease of B cell gene expression.

VEGF-A165b Is an Endogenous Neuroprotective Splice Isoform of Vascular Endothelial Growth Factor A inVivo and inVitro (2013)
Journal Article
Beazley-Long, N., Hua, J., Jehle, T., Hulse, R. P., Dersch, R., Lehrling, C., …Donaldson, L. F. (2013). VEGF-A165b Is an Endogenous Neuroprotective Splice Isoform of Vascular Endothelial Growth Factor A inVivo and inVitro. American Journal of Pathology, 183(3), 918-929. https://doi.org/10.1016/j.ajpath.2013.05.031

Vascular endothelial growth factor (VEGF) A is generated as two isoform families by alternative RNA splicing, represented by VEGF-A165a and VEGF-A165b. These isoforms have opposing actions on vascular permeability, angiogenesis, and vasodilatation. T... Read More about VEGF-A165b Is an Endogenous Neuroprotective Splice Isoform of Vascular Endothelial Growth Factor A inVivo and inVitro.

A single-arm, phase II study of the anti-BLYS monoclonal antibody belimumab in symptomatic waldenstrom macroglobulinemia (2013)
Journal Article
Bishton, M., Spencer, A., Dickinson, M., & Ritchie, D. (2013). A single-arm, phase II study of the anti-BLYS monoclonal antibody belimumab in symptomatic waldenstrom macroglobulinemia. Clinical Lymphoma, Myeloma and Leukemia, 13(5), 575-578. https://doi.org/10.1016/j.clml.2013.04.006

Background: The B-lymphocyte stimulator (BLYS) protein is known to regulate immunoglobulin in normal B cells, and be overexpressed in B-cell malignancies, including Waldenstrom macroglobulinemia (WM). Patients and Methods: This trial evaluated the sa... Read More about A single-arm, phase II study of the anti-BLYS monoclonal antibody belimumab in symptomatic waldenstrom macroglobulinemia.

Redox Environment, Free Radical, and Oxidative DNA Damage (2013)
Journal Article
Storr, S. J., Woolston, C. M., Zhang, Y., & Martin, S. G. (2013). Redox Environment, Free Radical, and Oxidative DNA Damage. Antioxidants and Redox Signaling, 18(18), 2399-2408. https://doi.org/10.1089/ars.2012.4920

Differential Phosphorylation of Smad1 Integrates BMP and Neurotrophin Pathways through Erk/Dusp in Axon Development (2013)
Journal Article
Finelli, M., Murphy, K., Chen, L., & Zou, H. (2013). Differential Phosphorylation of Smad1 Integrates BMP and Neurotrophin Pathways through Erk/Dusp in Axon Development. Cell Reports, 3(5), 1592-1606. https://doi.org/10.1016/j.celrep.2013.04.011

Sensory axon development requires concerted actions of growth factors for the precise control of axonal outgrowth and target innervation. How developing sensory neurons integrate different cues is poorly understood. We demonstrate here that Smad1 act... Read More about Differential Phosphorylation of Smad1 Integrates BMP and Neurotrophin Pathways through Erk/Dusp in Axon Development.

The TBC/RabGAP Armus Coordinates Rac1 and Rab7 Functions during Autophagy (2013)
Journal Article
Carroll, B., Mohd-Naim, N., Maximiano, F., Frasa, M., McCormack, J., Finelli, M., …Braga, V. (2013). The TBC/RabGAP Armus Coordinates Rac1 and Rab7 Functions during Autophagy. Developmental Cell, 25(1), 15-28. https://doi.org/10.1016/j.devcel.2013.03.005

Expression of the calpain system is associated with poor clinical outcome in gastro-oesophageal adenocarcinomas (2013)
Journal Article
Storr, S. J., Pu, X., Davis, J., Lobo, D., Reece-Smith, A. M., Parsons, S. L., …Martin, S. G. (2013). Expression of the calpain system is associated with poor clinical outcome in gastro-oesophageal adenocarcinomas. Journal of Gastroenterology, 48(11), 1213-1221. https://doi.org/10.1007/s00535-012-0743-4

Cytocompatibility, degradation, mechanical property retention and ion release profiles for phosphate glass fibre reinforced composite rods (2013)
Journal Article
Felfel, R., Ahmed, I., Parsons, A., Palmer, G., Sottile, V., & Rudd, C. (2013). Cytocompatibility, degradation, mechanical property retention and ion release profiles for phosphate glass fibre reinforced composite rods. Materials Science and Engineering: C, 33(4), https://doi.org/10.1016/j.msec.2012.12.089

Fibre reinforced composites have recently received much attention as potential bone fracture fixation applications. Bioresorbable composites based on poly lactic acid (PLA) and phosphate based glass fibre were investigated according to ion release, d... Read More about Cytocompatibility, degradation, mechanical property retention and ion release profiles for phosphate glass fibre reinforced composite rods.

The regulation of human papillomavirus gene expression by the E2 protein: keeping a finger in every pie (2012)
Book Chapter
Graham, S. V., & Gaston, K. L. (2012). The regulation of human papillomavirus gene expression by the E2 protein: keeping a finger in every pie. In K. Gaston (Ed.), Small DNA tumour viruses, 37--53. Caister Academic Press

The human papillomavirus (HPV) genome is around 8000 base pairs in length and it encodes only eight proteins, a limited number of protein isoforms and no known microRNAs. Despite this relative paucity of genes and gene products these viruses are high... Read More about The regulation of human papillomavirus gene expression by the E2 protein: keeping a finger in every pie.