Outputs (820)

Making remote measurement technology work in multiple sclerosis, epilepsy and depression: survey of healthcare professionals (2022)
Journal Article
Andrews, J. A., Craven, M. P., Lang, A. R., Guo, B., Morriss, R., Hollis, C., & RADAR-CNS Consortium. (2022). Making remote measurement technology work in multiple sclerosis, epilepsy and depression: survey of healthcare professionals. BMC Medical Informatics and Decision Making, 22(1), Article 125. https://doi.org/10.1186/s12911-022-01856-z

BACKGROUND: Epilepsy, multiple sclerosis(MS) and depression are long term, central nervous system disorders which have a significant impact on everyday life. Evaluating symptoms of these conditions is problematic and typically involves repeated visit... Read More about Making remote measurement technology work in multiple sclerosis, epilepsy and depression: survey of healthcare professionals.

Time-limited self-sustaining rhythms and state transitions in brain networks (2022)
Journal Article
Huo, S., Zou, Y., Kaiser, M., & Liu, Z. (2022). Time-limited self-sustaining rhythms and state transitions in brain networks. Physical Review Research, 4(2), Article 023076. https://doi.org/10.1103/PhysRevResearch.4.023076

Resting-state networks usually show time-limited self-sustaining oscillatory patterns (TLSOPs) with the characteristic features of multiscaled rhythms and frequent switching between different rhythms, but the underlying mechanisms remain unclear. To... Read More about Time-limited self-sustaining rhythms and state transitions in brain networks.

A randomised controlled trial investigating the clinical and cost-effectiveness of Alpha-Stim AID cranial electrotherapy stimulation (CES) in patients seeking treatment for moderate severity depression in primary care (Alpha-Stim-D Trial) (2022)
Journal Article
Patel, S., Boutry, C., Patel, P., Craven, M. P., Guo, B., Zafar, A., …Morriss, R. (2022). A randomised controlled trial investigating the clinical and cost-effectiveness of Alpha-Stim AID cranial electrotherapy stimulation (CES) in patients seeking treatment for moderate severity depression in primary care (Alpha-Stim-D Trial). Trials, 23(1), Article 250. https://doi.org/10.1186/s13063-022-06192-1

Background: Major depression is the second leading cause of years lost to disability worldwide and is a leading contributor to suicide. However, first-line antidepressants are only fully effective for 33%, and only 40% of those offered psychological... Read More about A randomised controlled trial investigating the clinical and cost-effectiveness of Alpha-Stim AID cranial electrotherapy stimulation (CES) in patients seeking treatment for moderate severity depression in primary care (Alpha-Stim-D Trial).

Cluster analyses of the TCGA and a TMA dataset using the coexpression of HSP27 and CRYAB improves alignment with clinical-pathological parameters of breast cancer and suggests different epichaperome influences for each sHSP (2022)
Journal Article
Quinlan, P. R., Figeuredo, G., Mongan, N., Jordan, L. B., Bray, S. E., Sreseli, R., …Quinlan, R. A. (2022). Cluster analyses of the TCGA and a TMA dataset using the coexpression of HSP27 and CRYAB improves alignment with clinical-pathological parameters of breast cancer and suggests different epichaperome influences for each sHSP. Cell Stress and Chaperones, 27(2), 177-188. https://doi.org/10.1007/s12192-022-01258-0

Our cluster analysis of the Cancer Genome Atlas for co-expression of HSP27 and CRYAB in breast cancer patients identified three patient groups based on their expression level combination (high HSP27 + low CRYAB; low HSP27 + high CRYAB; similar HSP27 ... Read More about Cluster analyses of the TCGA and a TMA dataset using the coexpression of HSP27 and CRYAB improves alignment with clinical-pathological parameters of breast cancer and suggests different epichaperome influences for each sHSP.

The COVID-19 pandemic has highlighted the need to invest in care home research infrastructure (2022)
Journal Article
Gordon, A. L., Rick, C., Juszczak, E., Montgomery, A., Howard, R., Guthrie, B., …Tate, V. (2022). The COVID-19 pandemic has highlighted the need to invest in care home research infrastructure. Age and Ageing, 51(3), Article afac052. https://doi.org/10.1093/ageing/afac052

The COVID-19 pandemic resulted in catastrophic levels of morbidity and mortality for care home residents. Despite this, research platforms for COVID-19 in care homes arrived late in the pandemic compared with other care settings. The Prophylactic The... Read More about The COVID-19 pandemic has highlighted the need to invest in care home research infrastructure.

Service user experiences of care recommendations from the 2014 NICE guideline for bipolar disorder: a survey (2022)
Journal Article
Roe, J., Cresswell, A., Mittal, S., Al-Uzri, M., Tanner, J., Moore, M., …Morriss, R. (2022). Service user experiences of care recommendations from the 2014 NICE guideline for bipolar disorder: a survey. Journal of Mental Health, 31(5), 724-731. https://doi.org/10.1080/09638237.2021.2022614

Clinical guidelines for mental health disorders produced by the National Institute of Care Excellence (NICE) emphasise a recovery-based approach clinical care with collaborative decision-making. The aim of the study was to explore service user experi... Read More about Service user experiences of care recommendations from the 2014 NICE guideline for bipolar disorder: a survey.

Virtual reality in post-stroke neurorehabilitation – a systematic review and meta-analysis (2021)
Journal Article
Khan, A., Podlasek, A., & Somaa, F. (2023). Virtual reality in post-stroke neurorehabilitation – a systematic review and meta-analysis. Topics in Stroke Rehabilitation, 30(1), 53-72. https://doi.org/10.1080/10749357.2021.1990468

Background
Stroke is a neurological disorder and one of the leading causes of disability worldwide. The patient may lose the ability to adequately move the extremities, perceive sensations, or ambulate independently. Recent experimental studies have... Read More about Virtual reality in post-stroke neurorehabilitation – a systematic review and meta-analysis.

Living with tinnitus and hyperacusis (2021)
Book
McKenna, L., Baguley, D., & McFerran, D. (2021). Living with tinnitus and hyperacusis. (New edition). Sheldon Press

Dynamic reconfiguration of macaque brain networks during natural vision (2021)
Journal Article
Ortiz-Rios, M., Balezeau, F., Haag, M., Schmid, M. C., & Kaiser, M. (2021). Dynamic reconfiguration of macaque brain networks during natural vision. NeuroImage, 244, Article 118615. https://doi.org/10.1016/j.neuroimage.2021.118615

Natural vision engages a wide range of higher-level regions that integrate visual information over the large-scale brain network. How interareal connectivity reconfigures during the processing of ongoing natural visual scenes and how these dynamic fu... Read More about Dynamic reconfiguration of macaque brain networks during natural vision.

BioDynaMo: a modular platform for high-performance agent-based simulation (2021)
Journal Article
Breitwieser, L., Hesam, A., de Montigny, J., Vavourakis, V., Iosif, A., Jennings, J., …Al-Ars, Z. (2022). BioDynaMo: a modular platform for high-performance agent-based simulation. Bioinformatics, 38(2), 453-460. https://doi.org/10.1093/bioinformatics/btab649

Motivation

Agent-based modeling is an indispensable tool for studying complex biological systems. However, existing simulation platforms do not always take full advantage of modern hardware and often have a field-specific software design.

Resul... Read More about BioDynaMo: a modular platform for high-performance agent-based simulation.