Outputs (135)

Immunomodulation with self-crosslinked polyelectrolyte multilayer-based coatings (2016)
Journal Article
Knopf-Marques, H., Singh, S., Htwe, S. S., Wolfova, L., Buffa, R., Bacharouche, J., Francius, G., Voegel, J.-C., Schaaf, P., Ghaemmaghami, A. M., Vrana, N. E., & Lavalle, P. (2016). Immunomodulation with self-crosslinked polyelectrolyte multilayer-based coatings. Biomacromolecules, 17(6), 2189-2198. https://doi.org/10.1021/acs.biomac.6b00429

This study aims to design an optimal polyelectrolyte multilayer film of poly-L-lysine (PLL) and hyaluronic acid(HA) as an anti-inflammatory cytokine release system in order to decrease the implant failure due to any immune reactions. The chemical mod... Read More about Immunomodulation with self-crosslinked polyelectrolyte multilayer-based coatings.

Personalised long-term follow-up of cochlear implant patients using remote care, compared with those on the standard care pathway: study protocol for a feasibility randomised controlled trial (2016)
Journal Article
Cullington, H., Kitterick, P. T., DeBold, L., Weal, M., Clarke, N., Newberry, E., & Aubert, L. (in press). Personalised long-term follow-up of cochlear implant patients using remote care, compared with those on the standard care pathway: study protocol for a feasibility randomised controlled trial. BMJ Open, 6(5), Article e011342. https://doi.org/10.1136/bmjopen-2016-011342

Introduction: Many resources are required to provide postoperative care to patients who receive a cochlear implant. The implant service commits to lifetime follow-up. The patient commits to regular adjustment and rehabilitation appointments in the fi... Read More about Personalised long-term follow-up of cochlear implant patients using remote care, compared with those on the standard care pathway: study protocol for a feasibility randomised controlled trial.

The effect of thermal processing in oil on the macromolecular integrity and acrylamide formation from starch of three potato cultivars organically fertilized (2016)
Journal Article
Varzakas, T., Alghamdi, A., Alghamdi, H., Linforth, R. S., Dinu, V., Besong, T. D., Gillis, R. B., Adams, G. G., Arapoglou, D., Connerton, I. F., Harding, S. E., & Israilides, C. (2016). The effect of thermal processing in oil on the macromolecular integrity and acrylamide formation from starch of three potato cultivars organically fertilized. Cogent Food and Agriculture, 2(1), https://doi.org/10.1080/23311932.2016.1180950

Starches from three organically produced cultivars of potato tuber (Lady Rosetta, Spunta and Voyager) have been studied in relation to (i) acrylamide production (ii) macromolecular integrity after frying with extra virgin olive oil, soybean oil and c... Read More about The effect of thermal processing in oil on the macromolecular integrity and acrylamide formation from starch of three potato cultivars organically fertilized.

Benefits to speech perception in noise from the binaural integration of electric and acoustic signals in simulated unilateral deafness (2016)
Journal Article
Ma, N., Morris, S. D., & Kitterick, P. T. (in press). Benefits to speech perception in noise from the binaural integration of electric and acoustic signals in simulated unilateral deafness. Ear and Hearing, 37(3), https://doi.org/10.1097/AUD.0000000000000252

Objectives: This study used vocoder simulations with normal-hearing (NH) listeners to (a) measure their ability to integrate speech information from a NH ear and a simulated cochlear implant (CI); and (b) investigate whether binaural integration is d... Read More about Benefits to speech perception in noise from the binaural integration of electric and acoustic signals in simulated unilateral deafness.

Applying theories of health behaviour and change to hearing health research: time for a new approach (2016)
Journal Article
Coulson, N. S., Ferguson, M. A., Henshaw, H., & Heffernan, E. (in press). Applying theories of health behaviour and change to hearing health research: time for a new approach. International Journal of Audiology, 55(sup3), Article S99-S104. https://doi.org/10.3109/14992027.2016.1161851

Objective:
In recent years, there has been an increase in the application of behavioural models, such as social cognition models, to the promotion of hearing health. Despite this, there exists a well-developed body of literature that suggests such m... Read More about Applying theories of health behaviour and change to hearing health research: time for a new approach.

Rethinking therapeutic strategies in cancer: wars, fields, anomalies and monsters (2016)
Journal Article
Stewart, S., & Rauch, C. (in press). Rethinking therapeutic strategies in cancer: wars, fields, anomalies and monsters. Social Theory and Health, https://doi.org/10.1057/sth.2016.4

This article argues that the excessive focus on cancer as an insidious living defect that needs to be destroyed has obscured the fact that cancer develops inside human beings. Therefore, in order to contribute to debates about new cancer therapies, w... Read More about Rethinking therapeutic strategies in cancer: wars, fields, anomalies and monsters.

The contribution of visual information to the perception of speech in noise with and without informative temporal fine structure (2016)
Journal Article
Stacey, P. C., Kitterick, P. T., Morris, S. D., & Sumner, C. J. (2016). The contribution of visual information to the perception of speech in noise with and without informative temporal fine structure. Hearing Research, 336, 17-28. https://doi.org/10.1016/j.heares.2016.04.002

Understanding what is said in demanding listening situations is assisted greatly by looking at the face of a talker. Previous studies have observed that normal-hearing listeners can benefit from this visual information when a talker’s voice is presen... Read More about The contribution of visual information to the perception of speech in noise with and without informative temporal fine structure.

The association between treatment adherence to nicotine patches and smoking cessation in pregnancy: a secondary analysis of a randomised controlled trial (2016)
Journal Article
Vaz, L. R., Aveyard, P., Cooper, S., Leonardi-Bee, J., & Coleman, T. (2016). The association between treatment adherence to nicotine patches and smoking cessation in pregnancy: a secondary analysis of a randomised controlled trial. Nicotine & Tobacco Research, 18(10), https://doi.org/10.1093/ntr/ntw080

Introduction

In non-pregnant ‘quitters’, adherence to nicotine replacement therapy (NRT) increases smoking cessation. We investigated relationships between adherence to placebo or NRT patches and cessation in pregnancy, including an assessment of... Read More about The association between treatment adherence to nicotine patches and smoking cessation in pregnancy: a secondary analysis of a randomised controlled trial.

Backbone NMR reveals allosteric signal transduction networks in the β1-adrenergic receptor (2016)
Journal Article
Isogai, S., Deupi, X., Opitz, C., Heydenreich, F. M., Tsai, C.-J., Brueckner, F., Schertler, G. F., Veprintsev, D. B., & Grzesiek, S. (in press). Backbone NMR reveals allosteric signal transduction networks in the β1-adrenergic receptor. Nature, 530(7589), https://doi.org/10.1038/nature16577

G protein-coupled receptors (GPCRs) are physiologically important transmembrane signalling proteins that trigger intracellular responses upon binding of extracellular ligands. Despite recent breakthroughs in GPCR crystallography1–3, the details of li... Read More about Backbone NMR reveals allosteric signal transduction networks in the β1-adrenergic receptor.

Cohort study of the impact of direct acting antiviral therapy in patients with chronic hepatitis C and decompensated cirrhosis (2016)
Journal Article
Foster, G. R., Irving, W. L., Cheung, M. C., Walker, A. J., Hudson, B. E., Verma, S., McLauchlan, J., Mutimer, D. J., Brown, A., Gelson, W. T., MacDonald, D. C., & Agarwal, K. (2016). Cohort study of the impact of direct acting antiviral therapy in patients with chronic hepatitis C and decompensated cirrhosis. Journal of Hepatology, 64(6), 1224-1231. https://doi.org/10.1016/j.jhep.2016.01.029

Background and Aims: All oral direct-acting antivirals (DAAs) effectively treat chronic hepatitis C virus (HCV) infection, but the benefits in advanced liver disease are unclear. We compared outcomes in treated and untreated patients with decompensat... Read More about Cohort study of the impact of direct acting antiviral therapy in patients with chronic hepatitis C and decompensated cirrhosis.