Skip to main content

Research Repository

Advanced Search

Outputs (135)

Pre-market version of a commercially available hearing instrument with a tinnitus sound generator: feasibility of evaluation in a clinical trial. (2016)
Journal Article
Sereda, M., Davies, J., & Hall, D. A. (in press). Pre-market version of a commercially available hearing instrument with a tinnitus sound generator: feasibility of evaluation in a clinical trial. International Journal of Audiology, https://doi.org/10.1080/14992027.2016.1254822

OBJECTIVE:
This report considers feasibility of conducting a UK trial of combination devices for tinnitus, using data from the study which evaluated different listener programmes available within the pre-market version of Oticon Alta with Tinnitus S... Read More about Pre-market version of a commercially available hearing instrument with a tinnitus sound generator: feasibility of evaluation in a clinical trial..

Women’s views on anxiety in pregnancy and the use of anxiety instruments: a qualitative study (2016)
Journal Article
Evans, K., Morrell, C. J., & Spiby, H. (in press). Women’s views on anxiety in pregnancy and the use of anxiety instruments: a qualitative study. Journal of Reproductive and Infant Psychology, https://doi.org/10.1080/02646838.2016.1245413

Objective: To explore women’s experience of anxiety in pregnancy and views on the use of anxiety instruments in antenatal care.

Background: Anxiety in pregnancy is associated with adverse birth outcomes, developmental and behavioural problems in... Read More about Women’s views on anxiety in pregnancy and the use of anxiety instruments: a qualitative study.

Solution conformation and flexibility of capsular polysaccharides from Neisseria meningitidis and glycoconjugates with the tetanus toxoid protein (2016)
Journal Article
Abdelhameed, A. S., Morris, G. A., Almutairi, F., Adams, G. G., Duvivier, P., Conrath, K., & Harding, S. E. (in press). Solution conformation and flexibility of capsular polysaccharides from Neisseria meningitidis and glycoconjugates with the tetanus toxoid protein. Scientific Reports, 6(1), 1-11. https://doi.org/10.1038/srep35588

The structural integrity of meningococcal native, micro-fluidized and activated capsular polysaccharides and their glycoconjugates – in the form most relevant to their potential use as vaccines (dilute solution) - have been investigated with respect... Read More about Solution conformation and flexibility of capsular polysaccharides from Neisseria meningitidis and glycoconjugates with the tetanus toxoid protein.

Developing Mn-doped lead sulfide quantum dots for MRI labels (2016)
Journal Article
Turyanska, L., Moro, F., Patanè, A., Barr, J., Köckenberger, W., Taylor, A., Faas, H., Fowler, M. J., Wigmore, P., Trueman, R. C., Williams, H. E. L., & Thomas, N. R. (2016). Developing Mn-doped lead sulfide quantum dots for MRI labels. Journal of Materials Chemistry B, 4(42), 6797-6802. https://doi.org/10.1039/c6tb02574a

Magnetic interactions of Mn2+ions in lead sulfide (PbS) nanocrystals with protons in water are probed by NMR and MRI. A thin layer of capping molecules enables free solvent diffusion to the nanocrystal surface resulting in a decrease of proton relaxa... Read More about Developing Mn-doped lead sulfide quantum dots for MRI labels.

Out of hours workload management: Bayesian inference for decision support in secondary care (2016)
Journal Article
Pérez López, I., Brown, M., Pinchin, J., Martindale, S., Sharples, S., Shaw, D. E., & Blakey, J. (in press). Out of hours workload management: Bayesian inference for decision support in secondary care. Artificial Intelligence in Medicine, 73, 34-44. https://doi.org/10.1016/j.artmed.2016.09.005

Objective: In this paper, we aim to evaluate the use of electronic technologies in Out of Hours (OoH) task-management for assisting the design of effective support systems in health care; targeting local facilities, wards or specific working groups.... Read More about Out of hours workload management: Bayesian inference for decision support in secondary care.

A paper-based in vitro model for on-chip investigation of the human respiratory system (2016)
Journal Article
Rahimi, R., Htwe, S. S., Ochoa, M., Donaldson, A., Zieger, M., Sood, R., Tamayol, A., Khademhosseini, A., Ghaemmaghami, A. M., & Ziaie, B. (in press). A paper-based in vitro model for on-chip investigation of the human respiratory system. Lab on a Chip, 16(22), https://doi.org/10.1039/C6LC00866F

Culturing cells at the air–liquid interface (ALI) is essential for creating functional in vitro models of lung tissues. We present the use of direct-patterned laser-treated hydrophobic paper as an effective semi-permeable membrane, ideal for ALI cell... Read More about A paper-based in vitro model for on-chip investigation of the human respiratory system.

Effective antigen presentation to helper T cells by human eosinophils (2016)
Journal Article
Farhan, R. K., Vickers, M. A., Ghaemmaghami, A. M., Hall, A. M., Barker, R. N., & Walsh, G. M. (in press). Effective antigen presentation to helper T cells by human eosinophils. Immunology, https://doi.org/10.1111/imm.12658

Although eosinophils are inflammatory cells, there is increasing attention on their immunomodulatory roles. For example, murine eosinophils can present antigen to CD4+ T helper (Th) cells, but it remains unclear whether human eosinophils also have th... Read More about Effective antigen presentation to helper T cells by human eosinophils.

A novel ketone diet enhances physical and cognitive performance (2016)
Journal Article
Murray, A. J., Knight, N. S., Cole, M. A., Cochlin, L. E., Carter, E., Tchabanenko, K., Pichulik, T., Gulston, M. K., Atherton, H. J., Schroeder, M. A., Deacon, R. M. J., Kashiwaya, Y., King, M. T., Pawlosky, R., Rawlins, J. N. P., Tyler, D. J., Griffin, J. L., Robertson, J., Veech, R. L., & Clarke, K. (2016). A novel ketone diet enhances physical and cognitive performance. FASEB Journal, 30(12), 4021-4032. https://doi.org/10.1096/fj.201600773R

Ketone bodies are the most energy efficient fuel, yielding more ATP per mole of substrate than pyruvate and increasing the free energy released from ATP hydrolysis. Elevation of circulating ketones via high-fat, low-carbohydrate diets has been used f... Read More about A novel ketone diet enhances physical and cognitive performance.

Assessment of a rapid liquid-based cytology method for measuring sputum cell counts (2016)
Journal Article
Martin, M., Lee, H., Meakin, G., Green, A., Simms, R., Reynolds, C., Winters, S., Shaw, D. E., Soomro, I. N., & Harrison, T. W. (in press). Assessment of a rapid liquid-based cytology method for measuring sputum cell counts. Thorax, https://doi.org/10.1136/thoraxjnl-2016-208817

Differential sputum cell counting is not widely available despite proven clinical utility in the management of asthma. We compared eosinophil counts obtained using liquid-based cytology (LBC), a routine histopathological processing method, and the cu... Read More about Assessment of a rapid liquid-based cytology method for measuring sputum cell counts.