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Outputs (6)

Cytomegalovirus, Epstein-Barr Virus, Herpes Simplex Virus, and Varicella Zoster Virus Infection Dynamics in People with Multiple Sclerosis from Northern Italy (2024)
Journal Article
Maple, P. A., Tanasescu, R., Constantinescu, C. S., Valentino, P., Capobianco, M., D’Orso, S., Borsellino, G., Battistini, L., Ristori, G., Mechelli, R., Salvetti, M., & Gran, B. (2024). Cytomegalovirus, Epstein-Barr Virus, Herpes Simplex Virus, and Varicella Zoster Virus Infection Dynamics in People with Multiple Sclerosis from Northern Italy. Pathogens, 13(6), Article 499. https://doi.org/10.3390/pathogens13060499

Previous exposure to Epstein–Barr virus (EBV) is strongly associated with the development of multiple sclerosis (MS). By contrast, past cytomegalovirus (CMV) infection may have no association, or be negatively associated with MS. This study aimed to... Read More about Cytomegalovirus, Epstein-Barr Virus, Herpes Simplex Virus, and Varicella Zoster Virus Infection Dynamics in People with Multiple Sclerosis from Northern Italy.

Sjogren's myelitis presenting as hemicord syndrome (2023)
Journal Article
Lee, A., Pande, I., & Gran, B. (2023). Sjogren's myelitis presenting as hemicord syndrome. Clinical Medicine, 23(4), 423-424. https://doi.org/10.7861/clinmed.2023-0158

We present a case where a 63-year-old right-handed man who presented with a 6-month history of progressive asymmetrical sensorimotor symptoms in lower limbs. This was associated with concomitant rash on the lower limbs, and mild sicca symptoms. MRI s... Read More about Sjogren's myelitis presenting as hemicord syndrome.

The Potential for EBV Vaccines to Prevent Multiple Sclerosis (2022)
Journal Article
Maple, P. A., Ascherio, A., Cohen, J. I., Cutter, G., Giovannoni, G., Shannon-Lowe, C., …Gran, B. (2022). The Potential for EBV Vaccines to Prevent Multiple Sclerosis. Frontiers in Neurology, 13, https://doi.org/10.3389/fneur.2022.887794

There is increasing evidence suggesting that Epstein-Barr virus infection is a causative factor of multiple sclerosis (MS). Epstein-Barr virus (EBV) is a human herpesvirus, Human Gammaherpesvirus 4. EBV infection shows two peaks: firstly, during earl... Read More about The Potential for EBV Vaccines to Prevent Multiple Sclerosis.

Coordinate based meta-analysis of motor functional imaging in Parkinson's: disease-specific patterns and modulation by dopamine replacement and deep brain stimulation (2019)
Journal Article
Xing, Y., Tench, C., Wongwandee, M., Schwarz, S., Bajaj, N., & Auer, D. (2020). Coordinate based meta-analysis of motor functional imaging in Parkinson's: disease-specific patterns and modulation by dopamine replacement and deep brain stimulation. Brain Imaging and Behavior, 14(4), 1263–1280. https://doi.org/10.1007/s11682-019-00061-3

Objective
To investigate factors affecting the pattern of motor brain activation reported in people with Parkinson’s (PwP), aiming to differentiate disease-specific features from treatment effects.

Methods
A co-ordinate-based-meta-analysis (CBMA... Read More about Coordinate based meta-analysis of motor functional imaging in Parkinson's: disease-specific patterns and modulation by dopamine replacement and deep brain stimulation.

Prehospital transdermal glyceryl trinitrate in patients with ultra-acute presumed stroke (RIGHT-2): an ambulance-based, randomised, sham-controlled, blinded, phase 3 trial (2019)
Journal Article
Bath, P. M., Scutt, P., Anderson, C. S., Appleton, J. P., Berge, E., Cala, L., Dixon, M., England, T. M., Godolphin, P. J., Havard, D., Haywood, L., Hepburn, T., Krishnan, K., Mair, G., Montgomery, A. A., Muir, K., Phillips, S. J., Pocock, S., Potter, J., Price, C., …Mir, R. (2019). Prehospital transdermal glyceryl trinitrate in patients with ultra-acute presumed stroke (RIGHT-2): an ambulance-based, randomised, sham-controlled, blinded, phase 3 trial. Lancet, 393(10175), 1009-1020. https://doi.org/10.1016/S0140-6736%2819%2930194-1

© 2019 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Background: High blood pressure is common in acute stroke and is a predictor of poor outcome; however, large trials of lowering blood pressure... Read More about Prehospital transdermal glyceryl trinitrate in patients with ultra-acute presumed stroke (RIGHT-2): an ambulance-based, randomised, sham-controlled, blinded, phase 3 trial.