Swallow Tail Sign: Revisited (2022)
Journal Article

The loss of the radiologic swallow tail sign on MRI scans of the substantia nigra is a promising diagnostic marker of Parkinson disease (1), although its anatom-ic underpinning is unclear. An early influential study showed th... Read More about Swallow Tail Sign: Revisited.

Tract-specific statistics based on diffusion-weighted probabilistic tractography (2022)
Journal Article

Diffusion-weighted neuroimaging approaches provide rich evidence for estimating the structural integrity of white matter in vivo, but typically do not assess white matter integrity for connections between two specific regions of the brain. Here, we p... Read More about Tract-specific statistics based on diffusion-weighted probabilistic tractography.

Quantifiable correlation of ToF-SIMS and XPS data from polymer surfaces with controlled amino acid and peptide content (2022)
Journal Article

Peptide-coated surfaces are widely employed in biomaterial design, but quantifiable correlation between surface composition and biological response is challenging due to, for example, instrumental limitations, a lack of suitable model surfaces or lim... Read More about Quantifiable correlation of ToF-SIMS and XPS data from polymer surfaces with controlled amino acid and peptide content.

Toward next-generation primate neuroscience: A collaboration-based strategic plan for integrative neuroimaging (2021)
Journal Article

Open science initiatives are creating opportunities to increase research coordination and impact in nonhuman primate (NHP) imaging. The PRIMatE Data and Resource Exchange community recently developed a collaboration-based strategic plan to advance NH... Read More about Toward next-generation primate neuroscience: A collaboration-based strategic plan for integrative neuroimaging.

Sulcal characteristics patterns and gyrification gradient at different stages of Anorexia Nervosa: a structural MRI evaluation (2021)
Journal Article

Previous research evidenced alterations of different cortical parameters in patients with acute Anorexia Nervosa (AN), but no study to date investigated the morphology of individual sulci and their relationship with other structural indices. Our stud... Read More about Sulcal characteristics patterns and gyrification gradient at different stages of Anorexia Nervosa: a structural MRI evaluation.

T2 heterogeneity as an in vivo marker of microstructural integrity in medial temporal lobe subfields in ageing and mild cognitive impairment (2021)
Journal Article

A better understanding of early brain changes that precede loss of independence in diseases like Alzheimer's disease (AD) is critical for development of disease-modifying therapies. Quantitative MRI, such as T2 relaxometry, can identify microstructur... Read More about T2 heterogeneity as an in vivo marker of microstructural integrity in medial temporal lobe subfields in ageing and mild cognitive impairment.

Beyond volumetry: Considering age-related changes in brain shape complexity using fractal dimensionality (2021)
Journal Article

Gray matter volume for cortical, subcortical, and ventricles all vary with age. However, these volumetric changes do not happen on their own, there are also age-related changes in cortical folding and other measures of brain shape. Fractal dimensiona... Read More about Beyond volumetry: Considering age-related changes in brain shape complexity using fractal dimensionality.

Scan Once, Analyse Many: Using large open-access neuroimaging datasets to understand the brain (2021)
Journal Article

We are now in a time of readily available brain imaging data. Not only are researchers now sharing data more than ever before, but additionally large-scale data collecting initiatives are underway with the vision that many future researchers will use... Read More about Scan Once, Analyse Many: Using large open-access neuroimaging datasets to understand the brain.

Investigating the effects of healthy cognitive aging on brain functional connectivity using 4.7 T resting-state functional Magnetic Resonance Imaging (2021)
Journal Article

Functional changes in the aging human brain have been previously reported using functional magnetic resonance imaging (fMRI). Earlier resting-state fMRI studies revealed an age-associated weakening of intra-system functional connectivity (FC) and age... Read More about Investigating the effects of healthy cognitive aging on brain functional connectivity using 4.7 T resting-state functional Magnetic Resonance Imaging.

“A little (PPI) MAGIC can take you a long way” : involving children and young people in research from inception of a novel medical device to multi-centre clinical trial Roald Dahl, James and the Giant Peach (1961) (2021)
Journal Article

Background: There is often a great urgency to be inclusive when conducting research and to focus efforts with groups and communities that can be referred to as marginalised. This is especially the case in research concerning medical devices aimed a... Read More about “A little (PPI) MAGIC can take you a long way” : involving children and young people in research from inception of a novel medical device to multi-centre clinical trial Roald Dahl, James and the Giant Peach (1961).

Age?related decrements in cortical gyrification: Evidence from an accelerated longitudinal dataset (2020)
Journal Article

Cortical gyrification has been found to decrease due to aging, but thus far this has only been examined in cross‐sectional samples. Interestingly, the topography of these age‐related differences in gyrification follows a distinct gradient along the c... Read More about Age?related decrements in cortical gyrification: Evidence from an accelerated longitudinal dataset.

Structural complexity is negatively associated with brain activity: a novel multimodal test of compensation theories of aging (2020)
Journal Article

Fractal dimensionality (FD) measures the complexity within the folds and ridges of cortical and subcortical structures. We tested the degree that FD might provide a new perspective on the atrophy-compensation hypothesis: age or disease-related atroph... Read More about Structural complexity is negatively associated with brain activity: a novel multimodal test of compensation theories of aging.

Measurement of fasted state gastric antral motility before and after a standard bioavailability and bioequivalence 240 mL drink of water: Validation of MRI method against concomitant perfused manometry in healthy participants (2020)
Journal Article

Objective The gastrointestinal environment in which drug products need to disintegrate before the drug can dissolve and be absorbed has not been studied in detail due to limitations, especially invasiveness of existing techniques. Minimal in vivo dat... Read More about Measurement of fasted state gastric antral motility before and after a standard bioavailability and bioequivalence 240 mL drink of water: Validation of MRI method against concomitant perfused manometry in healthy participants.

Age-related differences in myeloarchitecture measured at 7 T (2020)
Journal Article

We have used the magnetisation transfer (MT) MRI measure as a primary measure of myelination in both the grey matter (GM) of the 78 cortical automated anatomical labelling (AAL) regions of the brain, and the underlying white matter in each region, in... Read More about Age-related differences in myeloarchitecture measured at 7 T.

Feasibility Study of a New MRI Mini-Capsule Device to Measure Whole Gut Transit Time in Pediatric Constipation (2020)
Journal Article

Objective: In England, 27,500 children are referred annually to hospital with constipation. An objective measure of whole gut transit time (WGTT) could aid management. The current standard WGTT assessment, the X-ray radiopaque marker (ROM) test, give... Read More about Feasibility Study of a New MRI Mini-Capsule Device to Measure Whole Gut Transit Time in Pediatric Constipation.

A data-driven approach to optimising the encoding for multi-shell diffusion MRI with application to neonatal imaging (2020)
Journal Article

Diffusion MRI has the potential to provide important information about the connectivity and microstructure of the human brain during normal and abnormal development, non-invasively and in vivo. Recent developments in MRI hardware and reconstruction m... Read More about A data-driven approach to optimising the encoding for multi-shell diffusion MRI with application to neonatal imaging.

XTRACT - Standardised protocols for automated tractography in the human and macaque brain (2020)
Journal Article

We present a new software package with a library of standardised tractography protocols devised for the robust automated extraction of white matter tracts both in the human and the macaque brain. Using in vivo data from the Human Connectome Project (... Read More about XTRACT - Standardised protocols for automated tractography in the human and macaque brain.

Operando visualisation of battery chemistry in a sodium-ion battery by 23Na magnetic resonance imaging (2020)
Journal Article

© 2020, The Author(s). Sodium-ion batteries are a promising battery technology for their cost and sustainability. This has led to increasing interest in the development of new sodium-ion batteries and new analytical methods to non-invasively, directl... Read More about Operando visualisation of battery chemistry in a sodium-ion battery by 23Na magnetic resonance imaging.

Improved fibre dispersion estimation using b-tensor encoding (2020)
Journal Article

© 2020 The Authors Measuring fibre dispersion in white matter with diffusion magnetic resonance imaging (MRI) is limited by an inherent degeneracy between fibre dispersion and microscopic diffusion anisotropy (i.e., the diffusion anisotropy expected... Read More about Improved fibre dispersion estimation using b-tensor encoding.

Towards HCP-Style macaque connectomes: 24-Channel 3T multi-array coil, MRI sequences and preprocessing (2020)
Journal Article

© 2020 The Author(s) Macaque monkeys are an important animal model where invasive investigations can lead to a better understanding of the cortical organization of primates including humans. However, the tools and methods for noninvasive image acquis... Read More about Towards HCP-Style macaque connectomes: 24-Channel 3T multi-array coil, MRI sequences and preprocessing.