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Welcome to Repository@Nottingham

The Repository@Nottingham is intended to be an Open Access showcase for the published research output of the university. Whenever possible, refereed documents accepted for publication, or finished artistic compositions presented in public, will be made available here in full digital format, and hyperlinks to standard published versions will be provided. See our Policies for further information.



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Efficacy and safety of elexacaftor plus tezacaftor plus ivacaftor versus tezacaftor plus ivacaftor in people with cystic fibrosis homozygous for F508del-CFTR: a 24-week, multicentre, randomised, double-blind, active-controlled, phase 3b trial (2021)
Journal Article
Sutharsan, S., McKone, E. F., Downey, D. G., Duckers, J., MacGregor, G., Tullis, E., Van Braeckel, E., Wainwright, C. E., Watson, D., Ahluwalia, N., Bruinsma, B. G., Harris, C., Lam, A. P., Lou, Y., Moskowitz, S. M., Tian, S., Yuan, J., Waltz, D., Mall, M. A., Aurora, P., …Wark, P. (2022). Efficacy and safety of elexacaftor plus tezacaftor plus ivacaftor versus tezacaftor plus ivacaftor in people with cystic fibrosis homozygous for F508del-CFTR: a 24-week, multicentre, randomised, double-blind, active-controlled, phase 3b trial. Lancet Respiratory Medicine, 10(3), 267-277. https://doi.org/10.1016/S2213-2600%2821%2900454-9

Background: Elexacaftor plus tezacaftor plus ivacaftor is a triple-combination cystic fibrosis transmembrane conductance regulator (CFTR) modulator regimen shown to be generally safe and efficacious in people with cystic fibrosis aged 12 years or old... Read More about Efficacy and safety of elexacaftor plus tezacaftor plus ivacaftor versus tezacaftor plus ivacaftor in people with cystic fibrosis homozygous for F508del-CFTR: a 24-week, multicentre, randomised, double-blind, active-controlled, phase 3b trial.

A novel self-curing active cold patch asphalt mixture: Performance evaluation and mechanism analysis (2025)
Journal Article
Xu, X., Gong, K., Sreeram, A., & Tan, Z. (2025). A novel self-curing active cold patch asphalt mixture: Performance evaluation and mechanism analysis. Case Studies in Construction Materials, 22, Article e04629. https://doi.org/10.1016/j.cscm.2025.e04629

Cold patch asphalt mixtures (CPAMs) are increasingly favored for pothole repairs in asphalt pavements due to their environmental benefits and ease of construction. However, their low strength and durability have hindered broader application, necessit... Read More about A novel self-curing active cold patch asphalt mixture: Performance evaluation and mechanism analysis.

Nano-aggregation of asphaltenes and its influence on the multiscale properties of bitumen recycled through multiple ageing and rejuvenation cycles (2025)
Journal Article
Hu, Y., Yin, Y., Sreeram, A., Liu, J., Si, W., Tang, D., & Airey, G. D. (2025). Nano-aggregation of asphaltenes and its influence on the multiscale properties of bitumen recycled through multiple ageing and rejuvenation cycles. Chemical Engineering Journal, 512, Article 162348. https://doi.org/10.1016/j.cej.2025.162348

With the growing emphasis on the circular economy in road materials, the possibility of continually recycling of bitumen through multiple life cycles has become a subject of increasing interest. A key factor limiting the recyclability of aged bitumen... Read More about Nano-aggregation of asphaltenes and its influence on the multiscale properties of bitumen recycled through multiple ageing and rejuvenation cycles.

Ergodiscord: An Operational and Distinct Notion of Quantumness of Correlations (2025)
Journal Article
Alimuddin, M., Chowdhury, S. R., Patra, R. K., Ghosh, S. B., Tufarelli, T., Adesso, G., & Banik, M. (in press). Ergodiscord: An Operational and Distinct Notion of Quantumness of Correlations. Physical Review Research,

Nonclassicality in composite quantum systems depicts several puzzling manifestations, with Einstein-PodolskyRosen entanglement, Schrödinger steering, and Bell nonlocality being the most celebrated ones. In addition to those, an unentangled quantum st... Read More about Ergodiscord: An Operational and Distinct Notion of Quantumness of Correlations.

Quantum Processes as Thermodynamic Resources: The Role of Non-Markovianity (2025)
Journal Article
Zambon, G., & Adesso, G. (in press). Quantum Processes as Thermodynamic Resources: The Role of Non-Markovianity. Physical Review Letters,

Quantum thermodynamics studies how quantum systems and operations may be exploited as sources of work to perform useful thermodynamic tasks. In real-world conditions, the evolution of open quantum systems typically displays memory effects, resulting... Read More about Quantum Processes as Thermodynamic Resources: The Role of Non-Markovianity.