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Welcome to Repository@Nottingham

The Repository@Nottingham is intended to be an Open Access showcase for the published research output of the university. Whenever possible, refereed documents accepted for publication, or finished artistic compositions presented in public, will be made available here in full digital format, and hyperlinks to standard published versions will be provided. See our Policies for further information.



Latest Additions

Conversation success in one-to-one and group conversation: a group concept mapping study of adults with normal and impaired hearing (2022)
Journal Article
Nicoras, R., Gotowiec, S., Hadley, L. V., Smeds, K., & Naylor, G. (in press). Conversation success in one-to-one and group conversation: a group concept mapping study of adults with normal and impaired hearing. International Journal of Audiology, 1-9. https://doi.org/10.1080/14992027.2022.2095538

Objective The concept of conversation success is undefined, although prior work has variously related it to accurate exchange of information, alignment between interlocutors, and good management of misunderstandings. This study aimed (1) to identify... Read More about Conversation success in one-to-one and group conversation: a group concept mapping study of adults with normal and impaired hearing.

Mitotic centromere-associated kinesin (MCAK): a potential cancer drug target (2011)
Journal Article
Sanhaji, M., Friel, C. T., Wordeman, L., Louwen, F., & Yuan, J. (2011). Mitotic centromere-associated kinesin (MCAK): a potential cancer drug target. Oncotarget, 2(12), 935-947. https://doi.org/10.18632/oncotarget.416

The inability to faithfully segregate chromosomes in mitosis results in chromosome instability, a hallmark of solid tumors. Disruption of microtubule dynamics contributes highly to mitotic chromosome instability. The kinesin-13 family is critical in... Read More about Mitotic centromere-associated kinesin (MCAK): a potential cancer drug target.

The kinesin-13 MCAK has an unconventional ATPase cycle adapted for microtubule depolymerization (2011)
Journal Article
Friel, C. T., & Howard, J. (2011). The kinesin-13 MCAK has an unconventional ATPase cycle adapted for microtubule depolymerization. EMBO Journal, 30(19), 3928-3939. https://doi.org/10.1038/emboj.2011.290

Unlike other kinesins, members of the kinesin-13 subfamily do not move directionally along microtubules but, instead, depolymerize them. To understand how kinesins with structurally similar motor domains can have such dissimilar functions, we elucida... Read More about The kinesin-13 MCAK has an unconventional ATPase cycle adapted for microtubule depolymerization.

Lipoprotein Deprivation Reveals a Cholesterol-Dependent Therapeutic Vulnerability in Diffuse Glioma Metabolism (2022)
Journal Article
Wood, J., Abdelrazig, S., Evseev, S., Ortori, C., Castellanos-Uribe, M., May, S. T., …Rahman, R. (2022). Lipoprotein Deprivation Reveals a Cholesterol-Dependent Therapeutic Vulnerability in Diffuse Glioma Metabolism. Cancers, 14(16), 3873. https://doi.org/10.3390/cancers14163873

Citation: Wood, J.; Abdelrazig, S.; Evseev, S.; Ortori, C.; Castellanos-Uribe, M.; May, S.T.; Barrett, D.A.; Diksin, M.; Chakraborty, S.; Kim, D.-H.; et al.

Experiencing mundane AI futures (2022)
Conference Proceeding
Pilling, M., Coulton, P., Lodge, T., Crabtreeb, A., & Chamberlain, A. (2022). Experiencing mundane AI futures. . https://doi.org/10.21606/drs.2022.283

Whilst popular visions of Artificial Intelligence (AI) are often presented through the lens of sentient machines, our lived experience of AI is more mundane and exemplified by so-called ‘smart’ products and services. Whilst this mundane reality is of... Read More about Experiencing mundane AI futures.