All Outputs (14)

Validation of a questionnaire for central nervous system aspects of joint pain: the CAP questionnaire (2024)
Journal Article
McWilliams, D., Georgopoulos, V., Patel, J., Millar, B., Smith, S., & Walsh, D. (2024). Validation of a questionnaire for central nervous system aspects of joint pain: the CAP questionnaire. Rheumatology, https://doi.org/10.1093/rheumatology/keae342

Background

Neuropathic-like pain, fatigue, cognitive difficulty, catastrophizing, anxiety, sleep disturbance, depression and widespread pain associate with a single factor in people with knee pain. We report the Central Aspects of Pain questionnai... Read More about Validation of a questionnaire for central nervous system aspects of joint pain: the CAP questionnaire.

The association of painful and non-painful morbidities with frailty: a cross sectional analysis of a cohort of community dwelling older people in England (2024)
Journal Article
Chaplin, W. J., Lewis, H. R., Shahtaheri, S. M., Millar, B. S., McWilliams, D. F., Gladman, J. R. F., & Walsh, D. A. (2024). The association of painful and non-painful morbidities with frailty: a cross sectional analysis of a cohort of community dwelling older people in England. BMC Geriatrics, 24, Article 158. https://doi.org/10.1186/s12877-023-04602-w

Introduction
The association between chronic pain and frailty might indicate that pain is an independent driver of frailty but might alternatively be explained by inclusion within frailty identification tools of morbidities that commonly lead to chr... Read More about The association of painful and non-painful morbidities with frailty: a cross sectional analysis of a cohort of community dwelling older people in England.

Feasibility of conducting a cohort randomized controlled trial assessing the effectiveness of a nurse-led package of care for knee pain (2023)
Journal Article
Fuller, A., Hall, M., Nomikos, P. A., Millar, B., Ogollah, R., Valdes, A., …Abhishek, A. (2024). Feasibility of conducting a cohort randomized controlled trial assessing the effectiveness of a nurse-led package of care for knee pain. Rheumatology, 63(6), 1582-1592. https://doi.org/10.1093/rheumatology/kead432

Objective
To evaluate the feasibility of conducting a cohort randomized controlled trial (RCT) of a nurse-led package of care for knee pain and determining a treatment sequence for use in a future trial.

Methods
This study was an open-label, thr... Read More about Feasibility of conducting a cohort randomized controlled trial assessing the effectiveness of a nurse-led package of care for knee pain.

Heading Frequency and Risk of Cognitive Impairment in Retired Male Professional Soccer Players (2023)
Journal Article
Espahbodi, S., Hogervorst, E., Macnab, T. P., Thanoon, A., Fernandes, G. S., Millar, B., …Zhang, W. (2023). Heading Frequency and Risk of Cognitive Impairment in Retired Male Professional Soccer Players. JAMA Network Open, 6(7), Article e2323822. https://doi.org/10.1001/jamanetworkopen.2023.23822

Importance Although professional soccer players appear to be at higher risk of neurodegenerative disease, the reason remains unknown.

Objective To examine whether heading frequency is associated with risk of cognitive impairment in retired profe... Read More about Heading Frequency and Risk of Cognitive Impairment in Retired Male Professional Soccer Players.

Cognitive Impairment and Self-Reported Dementia in UK Retired Professional Soccer Players: A Cross Sectional Comparative Study (2023)
Journal Article
Macnab, T. P., Espahbodi, S., Hogervorst, E., Thanoon, A., Fernandes, G. S., Millar, B., …Zhang, W. (2023). Cognitive Impairment and Self-Reported Dementia in UK Retired Professional Soccer Players: A Cross Sectional Comparative Study. Sports Medicine - Open, 9, Article 43. https://doi.org/10.1186/s40798-023-00588-2

Background
Previous studies based on death certificates have found professional soccer players were more likely to die with neurodegenerative diseases, including dementia. Therefore, this study aimed to investigate whether retired professional male... Read More about Cognitive Impairment and Self-Reported Dementia in UK Retired Professional Soccer Players: A Cross Sectional Comparative Study.

The bidirectional relationship between chronic joint pain and frailty: data from the Investigating Musculoskeletal Health and Wellbeing cohort (2023)
Journal Article
Chaplin, W. J., McWilliams, D. F., Millar, B. S., Gladman, J. R. F., & Walsh, D. A. (2023). The bidirectional relationship between chronic joint pain and frailty: data from the Investigating Musculoskeletal Health and Wellbeing cohort. BMC Geriatrics, 23(1), Article 273. https://doi.org/10.1186/s12877-023-03949-4

Background: Pain and frailty are associated, but this relationship is insufficiently understood. We aimed to test whether there is a unidirectional or bidirectional relationship between joint pain and frailty. Methods: Data were from Investigating Mu... Read More about The bidirectional relationship between chronic joint pain and frailty: data from the Investigating Musculoskeletal Health and Wellbeing cohort.

Reproducible microbiome composition signatures of anxiety and depressive symptoms (2023)
Journal Article
Kouraki, A., Kelly, A., Vijay, A., Gohir, S., Astbury, S., Georgopoulos, V., …Valdes, A. M. (2023). Reproducible microbiome composition signatures of anxiety and depressive symptoms. Computational and Structural Biotechnology Journal, 21, 5326-5336. https://doi.org/10.1016/j.csbj.2023.10.035

The gut microbiome is a significant contributor to mental health, with growing evidence linking its composition to anxiety and depressive disorders. Gut microbiome composition is associated with signs of anxiety and depression both in clinically diag... Read More about Reproducible microbiome composition signatures of anxiety and depressive symptoms.

AB1432 THE ASSOCIATION OF PAINFUL AND NON-PAINFUL COMORBIDITIES WITH CENTRAL MECHANISMS OF KNEE PAIN (2022)
Presentation / Conference Contribution
Lewis, H., Chaplin, W., Mcwilliams, D., Millar, B., Shahtaheri, S., Gladman, J., & Walsh, D. (2022). AB1432 THE ASSOCIATION OF PAINFUL AND NON-PAINFUL COMORBIDITIES WITH CENTRAL MECHANISMS OF KNEE PAIN. Annals of the Rheumatic Diseases, 81(Suppl 1), 1822. https://doi.org/10.1136/annrheumdis-2022-eular.1586

Central pain mechanisms predict physical inactivity at 1-year in individuals with knee pain (2022)
Presentation / Conference Contribution
Habib, M., Smith, S., Chaplin, W., Millar, B., McWilliams, D., & Walsh, D. (2022). Central pain mechanisms predict physical inactivity at 1-year in individuals with knee pain. Osteoarthritis and Cartilage, 30(Sup 1), S379. https://doi.org/10.1016/j.joca.2022.02.511

Purpose: Pain is the primary clinical manifestation in individuals with osteoarthritis (OA). It is an unpleasant and distressing experience, particularly during weight-bearing activities, inhibiting activity, and reducing quality of life. Two groups... Read More about Central pain mechanisms predict physical inactivity at 1-year in individuals with knee pain.

Fidelity assessment of nurse-led non-pharmacological package of care for knee pain in the package development phase of a feasibility randomised controlled trial based in secondary care: A mixed methods study (2021)
Journal Article
Nomikos, P. A., Hall, M., Fuller, A., Millar, B., Ogollah, R., Valdes, A., …Abhishek, A. (2021). Fidelity assessment of nurse-led non-pharmacological package of care for knee pain in the package development phase of a feasibility randomised controlled trial based in secondary care: A mixed methods study. BMJ Open, 11(7), Article e045242. https://doi.org/10.1136/bmjopen-2020-045242

Objectives To evaluate fidelity of delivery of a nurse-led non-pharmacological complex intervention for knee pain. Setting Secondary care. Single-centre study. Study design Mixed methods study. Participants Eighteen adults with chronic knee pain. Inc... Read More about Fidelity assessment of nurse-led non-pharmacological package of care for knee pain in the package development phase of a feasibility randomised controlled trial based in secondary care: A mixed methods study.

The Central Aspects of Pain in the Knee (CAP-Knee) questionnaire; a mixed-methods study of a self-report instrument for assessing central mechanisms in people with knee pain (2021)
Journal Article
Akin-Akinyosoye, K., James, R. J. E., Mcwilliams, D. F., Millar, B., Das Nair, R., Ferguson, E., & Walsh, D. A. (2021). The Central Aspects of Pain in the Knee (CAP-Knee) questionnaire; a mixed-methods study of a self-report instrument for assessing central mechanisms in people with knee pain. Osteoarthritis and Cartilage, 29(6), 802-814. https://doi.org/10.1016/j.joca.2021.02.562

OBJECTIVES: Pain is the prevailing symptom of knee osteoarthritis. Central sensitisation creates discordance between pain and joint pathology. We previously reported a central pain mechanisms trait derived from 8 discrete characteristics: neuropathic... Read More about The Central Aspects of Pain in the Knee (CAP-Knee) questionnaire; a mixed-methods study of a self-report instrument for assessing central mechanisms in people with knee pain.

The East Midlands Knee Pain Multiple Randomised Controlled Trial Cohort Study: Cohort Establishment and Feasibility study protocol (2020)
Journal Article
Hall, M. C., Fuller, A., Nomikos, P. A., Millar, B., Ogollah, R., Valdes, A., …Abhishek, A. (2020). The East Midlands Knee Pain Multiple Randomised Controlled Trial Cohort Study: Cohort Establishment and Feasibility study protocol. BMJ Open, 10(9), Article e037760

Introduction: Knee pain and osteoarthritis (OA) are a common cause of disability. The UK National Institute of Health and Care Excellence (NICE) OA guidelines recommend education, exercise and weight-loss advice (if overweight) as core interventions... Read More about The East Midlands Knee Pain Multiple Randomised Controlled Trial Cohort Study: Cohort Establishment and Feasibility study protocol.

East Midlands knee pain multiple randomised controlled trial cohort study: cohort establishment and feasibility study protocol (2020)
Journal Article
Hall, M., Fuller, A., Nomikos, P. A., Millar, B., Ogollah, R., Valdes, A., …Abhishek, A. (2020). East Midlands knee pain multiple randomised controlled trial cohort study: cohort establishment and feasibility study protocol. BMJ Open, 10(9), Article e037760. https://doi.org/10.1136/bmjopen-2020-037760

© 2020 BMJ Open Introduction Knee pain due to osteoarthritis (OA) is a common cause of disability. The UK National Institute for Health and Care Excellence OA guidelines recommend education, exercise and weight loss advice (if overweight) as core int... Read More about East Midlands knee pain multiple randomised controlled trial cohort study: cohort establishment and feasibility study protocol.

Investigating musculoskeletal health and wellbeing; A cohort study protocol (2020)
Journal Article
Millar, B., McWilliams, D. F., Abhishek, A., Akin-Akinyosoye, K., Auer, D. P., Chapman, V., …Walsh, D. A. (2020). Investigating musculoskeletal health and wellbeing; A cohort study protocol. BMC Musculoskeletal Disorders, 21(1), Article 182. https://doi.org/10.1186/s12891-020-03195-4

© 2020 The Author(s). Background: In an ageing population, pain, frailty and disability frequently coexist across a wide range of musculoskeletal diagnoses, but their associations remain incompletely understood. The Investigating Musculoskeletal Heal... Read More about Investigating musculoskeletal health and wellbeing; A cohort study protocol.