All Outputs (3244)

Regional variations and deprivation are linked to poorer access to laparoscopic and robotic colorectal surgery: a national study in England (2023)
Journal Article
Morton, A. J., Simpson, A., & Humes, D. J. (2024). Regional variations and deprivation are linked to poorer access to laparoscopic and robotic colorectal surgery: a national study in England. Techniques in Coloproctology, 28(1), Article 9. https://doi.org/10.1007/s10151-023-02874-3

Background: Laparoscopic and now robotic colorectal surgery has rapidly increased in prevalence; however, little is known about how uptake varies by region and sociodemographics. The aim of this study was to quantify the uptake of minimally invasive... Read More about Regional variations and deprivation are linked to poorer access to laparoscopic and robotic colorectal surgery: a national study in England.

BubbleDet: a Python package to compute functional determinants for bubble nucleation (2023)
Journal Article
Ekstedt, A., Gould, O., & Hirvonen, J. (2023). BubbleDet: a Python package to compute functional determinants for bubble nucleation. Journal of High Energy Physics, 2023(12), Article 56. https://doi.org/10.1007/jhep12%282023%29056

We present a Python package BubbleDet for computing one-loop functional determinants around spherically symmetric background fields. This gives the next-to-leading order correction to both the vacuum decay rate, at zero temperature, and to the bubble... Read More about BubbleDet: a Python package to compute functional determinants for bubble nucleation.

Cost-effectiveness of Spironolactone for Adult Female Acne (SAFA): economic evaluation alongside a randomised controlled trial (2023)
Journal Article
Pyne, S., Sach, T. H., Lawrence, M., Renz, S., Eminton, Z., Stuart, B., …Santer, M. (2023). Cost-effectiveness of Spironolactone for Adult Female Acne (SAFA): economic evaluation alongside a randomised controlled trial. BMJ Open, 13(12), Article e073245. https://doi.org/10.1136/bmjopen-2023-073245

Objective This study aims to estimate the cost-effectiveness of oral spironolactone plus routine topical treatment compared with routine topical treatment alone for persistent acne in adult women from a British NHS perspective over 24 weeks. Design E... Read More about Cost-effectiveness of Spironolactone for Adult Female Acne (SAFA): economic evaluation alongside a randomised controlled trial.

Ensemble strategy using particle swarm optimisation variant and enhanced local search capability (2023)
Journal Article
Hong, L., Wang, G., Özcan, E., & Woodward, J. (2023). Ensemble strategy using particle swarm optimisation variant and enhanced local search capability. Swarm and Evolutionary Computation, 84, Article 101452. https://doi.org/10.1016/j.swevo.2023.101452

Particle swarm optimisation is a population-based algorithm for evolutionary computation. A notable recent research direction has been to combine different effective mechanisms to enhance both exploration and exploitation capabilities while employing... Read More about Ensemble strategy using particle swarm optimisation variant and enhanced local search capability.

Targeted DPPC/DMPG surface-modified voriconazole lipid nanoparticles control invasive pulmonary aspergillosis in immunocompromised population: in-vitro and in-vivo assessment (2023)
Journal Article
Fayyaz, H. A., EL-Massik, M. A., Bahey-El-Din, M., Abdel-Bary, A., Abdallah, O. Y., & Eltaher, H. M. (2024). Targeted DPPC/DMPG surface-modified voriconazole lipid nanoparticles control invasive pulmonary aspergillosis in immunocompromised population: in-vitro and in-vivo assessment. International Journal of Pharmaceutics, 649, Article 123663. https://doi.org/10.1016/j.ijpharm.2023.123663

Invasive pulmonary aspergillosis (IPA) is the most devastating Aspergillus-related lung disease. Voriconazole (VRZ) is the first-line treatment against IPA. Despite availability in oral and parenteral dosage forms, risks of systemic toxicity dictate... Read More about Targeted DPPC/DMPG surface-modified voriconazole lipid nanoparticles control invasive pulmonary aspergillosis in immunocompromised population: in-vitro and in-vivo assessment.

Pneumococcal serotypes and risk factors in adult community-acquired pneumonia 2018–20; a multicentre UK cohort study (2023)
Journal Article
Lansbury, L., Lawrence, H., McKeever, T. M., French, N., Aston, S., Hill, A. T., …Lim, W. S. (2024). Pneumococcal serotypes and risk factors in adult community-acquired pneumonia 2018–20; a multicentre UK cohort study. Lancet Regional Health – Europe, 37, Article 100812. https://doi.org/10.1016/j.lanepe.2023.100812

Background: Higher-valency pneumococcal vaccines are anticipated. We aimed to describe serotype distribution and risk factors for vaccine-serotype community-acquired pneumonia (CAP) in the two years pre-SARS-CoV-2 pandemic. Methods: We conducted a pr... Read More about Pneumococcal serotypes and risk factors in adult community-acquired pneumonia 2018–20; a multicentre UK cohort study.

"Should I stay (on X) or should I go?” Three causes of journalistic self-censorship on x (2023)
Book Chapter
Dagoula, C. (2023). "Should I stay (on X) or should I go?” Three causes of journalistic self-censorship on x. In J. Steel, & J. Petley (Eds.), The Routledge Companion to Freedom of Expression and Censorship. Routledge. https://doi.org/10.4324/9780429262067

Twitter is widely considered to be an integral part of journalists’ everyday routines. Its immediacy and instantaneity as well as the networking possibilities the platform affords has benefitted journalism in various ways, particularly with regards t... Read More about "Should I stay (on X) or should I go?” Three causes of journalistic self-censorship on x.

The Law Commission’s “Structured Discretion” Rape Shield: A Critique (2023)
Journal Article
THOMASON, M. (2023). The Law Commission’s “Structured Discretion” Rape Shield: A Critique. Archbold Review, 2023(10), 4-10

Taking up a Chapter of its own in the Law Commission’s mammoth Evidence in Sexual Offences Prosecutions Consultation Paper are proposals to reform the admissibility rules for sexual behaviour (née sexual history) evidence (SBE). Though the Law Comm... Read More about The Law Commission’s “Structured Discretion” Rape Shield: A Critique.

Chronic Lymphocytic Leukemia Therapy Guided by Measurable Residual Disease (2023)
Journal Article
Munir, T., Cairns, D. A., Bloor, A., Allsup, D., Cwynarski, K., Pettitt, A., Paneesha, S., Fox, C. P., Eyre, T. A., Forconi, F., Elmusharaf, N., Kennedy, B., Gribben, J., Pemberton, N., Sheehy, O., Preston, G., Schuh, A., Walewska, R., Duley, L., Howard, D., …Hillmen, P. (2024). Chronic Lymphocytic Leukemia Therapy Guided by Measurable Residual Disease. New England Journal of Medicine, 390(4), 326-337. https://doi.org/10.1056/nejmoa2310063

BACKGROUND: The combination of ibrutinib and venetoclax has been shown to improve outcomes in patients with chronic lymphocytic leukemia (CLL) as compared with chemoimmunotherapy. Whether ibrutinib-venetoclax and personalization of treatment duration... Read More about Chronic Lymphocytic Leukemia Therapy Guided by Measurable Residual Disease.

Flow Matching for Scalable Simulation-Based Inference (2023)
Presentation / Conference Contribution
Wildberger, J., Dax, M., Green, S., Buchholz, S., Macke, J., & Schölkopf, B. (2023, December). Flow Matching for Scalable Simulation-Based Inference. Poster presented at Thirty-seventh Conference on Neural Information Processing Systems (NeurIPS 2023), New Orleans, USA

Neural posterior estimation methods based on discrete normalizing flows have become established tools for simulation-based inference (SBI), but scaling them to high-dimensional problems can be challenging. Building on recent advances in generative mo... Read More about Flow Matching for Scalable Simulation-Based Inference.

Richter's transformation: Transforming the clinical landscape (2023)
Journal Article
Barrett, A., Appleby, N., Dreau, H., Fox, C., Munir, T., & Eyre, T. (2024). Richter's transformation: Transforming the clinical landscape. Blood Reviews, 64, Article 101163. https://doi.org/10.1016/j.blre.2023.101163

Richter transformation (RT) represents an aggressive histological transformation from chronic lymphocytic leukaemia, most often to a large B cell lymphoma. It is characterised by chemo-resistance and subsequent short survival. Drug development has st... Read More about Richter's transformation: Transforming the clinical landscape.

Modelling and experimental study of laser-assisted milling of fibre reinforced SiC/Ti-6Al-4V metal matrix composite (2023)
Journal Article
Mypati, O., Panzer, J., Robles-Linares, J. A., Zan, S., Liao, Z., & Axinte, D. (2024). Modelling and experimental study of laser-assisted milling of fibre reinforced SiC/Ti-6Al-4V metal matrix composite. Materials and Design, 237, Article 112552. https://doi.org/10.1016/j.matdes.2023.112552

Metal matrix composites (MMCs) offer unique advantageous mechanical properties by strengthening a ductile metal matrix with a ceramic reinforcement (e.g., Ti6Al-4 V/SiCf). However, their heterogeneous composition poses machining challenges including... Read More about Modelling and experimental study of laser-assisted milling of fibre reinforced SiC/Ti-6Al-4V metal matrix composite.

Calculative trust, relational trust, and organizational performance: A meta-analytic structural equation modeling approach (2023)
Journal Article
Bai, J., Xin, Z., Su, J., & Wang, C. (2024). Calculative trust, relational trust, and organizational performance: A meta-analytic structural equation modeling approach. Journal of Business Research, 172, Article 114435. https://doi.org/10.1016/j.jbusres.2023.114435

We draw on transaction cost economics and social exchange theory to explore how two different types of inter-organizational trust, namely, calculative trust and relational trust, affect organizational performance. Our meta-analysis of 60 empirical st... Read More about Calculative trust, relational trust, and organizational performance: A meta-analytic structural equation modeling approach.

The amino acid transporter SLC7A11 expression in breast cancer (2023)
Journal Article
Nath, P., Alfarsi, L. H., El-Ansari, R., Masisi, B. K., Erkan, B., Fakroun, A., …Green, A. R. (2024). The amino acid transporter SLC7A11 expression in breast cancer. Cancer Biology and Therapy, 25(1), Article 2291855. https://doi.org/10.1080/15384047.2023.2291855

Breast cancer (BC), characterized by its diverse molecular profiles and clinical outcomes, presents a significant challenge in the development of effective therapeutic strategies. Metabolic reprogramming, a defining characteristic of cancer, has emer... Read More about The amino acid transporter SLC7A11 expression in breast cancer.

Analysis of Endothelial Progenitor Cell Subtypes as Clinical Biomarkers for Elderly Patients with Ischaemic Stroke (2023)
Journal Article
ABDULKADIR, R., RAKKAR, K., OTHMAN, O., SPRIGG, N., BATH, P., & BAYRAKTUTAN, U. (2023). Analysis of Endothelial Progenitor Cell Subtypes as Clinical Biomarkers for Elderly Patients with Ischaemic Stroke. Scientific Reports, 13, Article 21843. https://doi.org/10.1038/s41598-023-48907-7

Endothelial progenitor cells (EPCs), expressing markers for stemness (CD34), immaturity (CD133) and endothelial maturity (KDR), may determine the extent of post-stroke vascular repair. Given the prevalence of stroke in elderly, this study explored wh... Read More about Analysis of Endothelial Progenitor Cell Subtypes as Clinical Biomarkers for Elderly Patients with Ischaemic Stroke.

Analysis of endothelial progenitor cell subtypes as clinical biomarkers for elderly patients with ischaemic stroke (2023)
Journal Article
Kadir, R. R. A., Rakkar, K., Othman, O. A., Sprigg, N., Bath, P. M., & Bayraktutan, U. (2023). Analysis of endothelial progenitor cell subtypes as clinical biomarkers for elderly patients with ischaemic stroke. Scientific Reports, 13(1), Article 21843. https://doi.org/10.1038/s41598-023-48907-7

Endothelial progenitor cells (EPCs), expressing markers for stemness (CD34), immaturity (CD133) and endothelial maturity (KDR), may determine the extent of post-stroke vascular repair. Given the prevalence of stroke in elderly, this study explored wh... Read More about Analysis of endothelial progenitor cell subtypes as clinical biomarkers for elderly patients with ischaemic stroke.

How Should a Vape Shop-Based Smoking Cessation Intervention Be Delivered? A Qualitative Study (2023)
Journal Article
Langley, T., Young, E., Hunter, A., & Bains, M. (2024). How Should a Vape Shop-Based Smoking Cessation Intervention Be Delivered? A Qualitative Study. Nicotine and Tobacco Research, 26(10), 1355-1361. https://doi.org/10.1093/ntr/ntad236

Introduction

Encouraging smokers to quit smoking tobacco using e-cigarettes could substantially reduce smoking-related diseases. Vape shops (VS) therefore have the potential to play an important role in supporting smoking cessation. The aim of thi... Read More about How Should a Vape Shop-Based Smoking Cessation Intervention Be Delivered? A Qualitative Study.

Authenticity: The state-of-the-art in Tourism Geographies (2023)
Journal Article
Rickly, J., Sharma, N., & Canavan, B. (2023). Authenticity: The state-of-the-art in Tourism Geographies. Tourism Geographies, https://doi.org/10.1080/14616688.2023.2290017

A leading concept in the field of tourism studies, authenticity has a unique relationship with tourism geographies. This state-of-the-art review focuses on this relationship. First, we identity key themes of authenticity research in tourism geographi... Read More about Authenticity: The state-of-the-art in Tourism Geographies.

Dog owner mental health is associated with dog behavioural problems, dog care and dog-facilitated social interaction: a prospective cohort study (2023)
Journal Article
Barcelos, A. M., Kargas, N., Assheton, P., Maltby, J., Hall, S., & Mills, D. S. (2023). Dog owner mental health is associated with dog behavioural problems, dog care and dog-facilitated social interaction: a prospective cohort study. Scientific Reports, 13(1), Article 21734. https://doi.org/10.1038/s41598-023-48731-z

Despite numerous qualitative and cross-sectional studies investigating how dog-related factors may impact owners’ well-being, empirical studies to test these causal effects are lacking. This prospective cohort study examined the correlation and poten... Read More about Dog owner mental health is associated with dog behavioural problems, dog care and dog-facilitated social interaction: a prospective cohort study.

Small Molecule Fluorescent Ligands for the Atypical Chemokine Receptor 3 (ACKR3) (2023)
Journal Article
Dekkers, S., Comez, D., Karsai, N., Arimont-Segura, M., Canals, M., Caspar, B., …Stocks, M. J. (2023). Small Molecule Fluorescent Ligands for the Atypical Chemokine Receptor 3 (ACKR3). ACS Medicinal Chemistry Letters, 15(1), 143–148. https://doi.org/10.1021/acsmedchemlett.3c00469

The atypical chemokine receptor 3 (ACKR3) is a receptor that induces cancer progression and metastasis in multiple cell types. Therefore, new chemical tools are required to study the role of ACKR3 in cancer and other diseases. In this study, fluoresc... Read More about Small Molecule Fluorescent Ligands for the Atypical Chemokine Receptor 3 (ACKR3).