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Synthesis of orchestrations of transducers for manufacturing (2018)
Presentation / Conference Contribution
De Giacomo, G., Vardi, M. Y., Felli, P., Alechina, N., & Logan, B. (2018). Synthesis of orchestrations of transducers for manufacturing.

In this paper, we model manufacturing processes and facilities as transducers (automata with output). The problem of whether a given manufacturing process can be realized by a given set of manufacturing resources can then be stated as an orchestratio... Read More about Synthesis of orchestrations of transducers for manufacturing.

Educating for a systems design approach to complex societal problems (2018)
Journal Article
Costa Junior, J. D., Diehl, J. C., & Secomandi, F. (2018). Educating for a systems design approach to complex societal problems. Journal of Engineering Design, 29(3), https://doi.org/10.1080/09544828.2018.1436162

Design education has devoted little attention to the topic of societal systems transformation in the context of sustainable development. This paper reports on a master‘s-level course that aims to build the capacity for design engineering students to... Read More about Educating for a systems design approach to complex societal problems.

Cutting Materials in Half: A Graph Theory Approach for Generating Crystal Surfaces and Its Prediction of 2D Zeolites (2018)
Journal Article
Witman, M., Ling, S., Boyd, P., Barthel, S., Haranczyk, M., Slater, B., & Smit, B. (2018). Cutting Materials in Half: A Graph Theory Approach for Generating Crystal Surfaces and Its Prediction of 2D Zeolites. ACS Central Science, 4(2), 235-245. https://doi.org/10.1021/acscentsci.7b00555

© 2018 American Chemical Society. Scientific interest in two-dimensional (2D) materials, ranging from graphene and other single layer materials to atomically thin crystals, is quickly increasing for a large variety of technological applications. Whil... Read More about Cutting Materials in Half: A Graph Theory Approach for Generating Crystal Surfaces and Its Prediction of 2D Zeolites.

Effects of sprint interval training on ectopic lipids and tissue-specific insulin sensitivity in men with non-alcoholic fatty liver disease (2018)
Journal Article
Sargeant, J. A., Bawden, S., Aithal, G. P., Simpson, E. J., Macdonald, I. A., Turner, M. C., …King, J. A. (2018). Effects of sprint interval training on ectopic lipids and tissue-specific insulin sensitivity in men with non-alcoholic fatty liver disease. European Journal of Applied Physiology, 118(4), 817-828. https://doi.org/10.1007/s00421-018-3818-y

Purpose: This study examined the feasibility of sprint interval exercise training (SIT) for men with non-alcoholic fatty liver disease (NAFLD) and its effects on intrahepatic triglyceride (IHTG), insulin sensitivity (hepatic and peripheral), visceral... Read More about Effects of sprint interval training on ectopic lipids and tissue-specific insulin sensitivity in men with non-alcoholic fatty liver disease.

Exposure to the ROCK inhibitor fasudil promotes gliogenesis of neural stem cells in vitro (2018)
Journal Article
Nizamudeen, Z. A., Chakrabarti, L., & Sottile, V. (2018). Exposure to the ROCK inhibitor fasudil promotes gliogenesis of neural stem cells in vitro. Stem Cell Research, 28, 75-86. https://doi.org/10.1016/j.scr.2018.02.001

Fasudil is a clinically approved Rho-associated protein kinase (ROCK) inhibitor that has been used widely to treat cerebral consequences of subarachnoid haemorrhage. It is known to have a positive effect on animal models of neurological disorders inc... Read More about Exposure to the ROCK inhibitor fasudil promotes gliogenesis of neural stem cells in vitro.

Dry-powder formulations of non-covalent protein complexes with linear or miktoarm copolymers for pulmonary delivery (2018)
Journal Article
Nieto-Orellana, A., Coghlan, D., Rothery, M., Falcone, F. H., Bosquillon, C., Childerhouse, N., …Stolnik, S. (2018). Dry-powder formulations of non-covalent protein complexes with linear or miktoarm copolymers for pulmonary delivery. International Journal of Pharmaceutics, 540(1-2), https://doi.org/10.1016/j.ijpharm.2018.02.008

Pulmonary delivery of protein therapeutics has considerable clinical potential for treating both local and systemic diseases. However, poor protein conformational stability, immunogenicity and protein degradation by proteolytic enzymes in the lung ar... Read More about Dry-powder formulations of non-covalent protein complexes with linear or miktoarm copolymers for pulmonary delivery.

Multifunctional serine protease inhibitor-coated water-soluble gold nanoparticles as a novel targeted approach for the treatment of inflammatory skin diseases (2018)
Journal Article
Limón, D., Fábrega, M. J., Calpena, A. C., Badia, J., Baldomà, L., & Pérez-García, L. (2018). Multifunctional serine protease inhibitor-coated water-soluble gold nanoparticles as a novel targeted approach for the treatment of inflammatory skin diseases. Bioconjugate Chemistry, 28(4), https://doi.org/10.1021/acs.bioconjchem.7b00717

The overexpression and increased activity of the serine protease Kallikrein 5 (KLK5) is characteristic of inflammatory skin diseases such as Rosacea. The use of inhibitors of this enzyme—such as 4-(2-aminoethyl)benzenesulfonyl fluoride hydrochloride... Read More about Multifunctional serine protease inhibitor-coated water-soluble gold nanoparticles as a novel targeted approach for the treatment of inflammatory skin diseases.

Suboptimal acclimation of photosynthesis to light in wheat canopies (2018)
Journal Article
Townsend, A. J., Retkute, R., Chinnathambi, K., Randall, J. W., Foulkes, J. F., Carmo-Silva, E., & Murchie, E. H. (in press). Suboptimal acclimation of photosynthesis to light in wheat canopies. Plant Physiology, 176(2), https://doi.org/10.1104/pp.17.01213

Photosynthetic acclimation (photoacclimation) is the process whereby leaves alter their morphology and/or biochemistry to optimise photosynthetic efficiency and productivity according to long-term changes in the light environment. Three-dimensional (... Read More about Suboptimal acclimation of photosynthesis to light in wheat canopies.

Heterologous expression of a novel drug transporter from the malaria parasite alters resistance to quinoline antimalarials (2018)
Journal Article
Tindall, S. M., Vallières, C., Lakhani, D. H., Islahudin, F., Ting, K.-N., & Avery, S. V. (in press). Heterologous expression of a novel drug transporter from the malaria parasite alters resistance to quinoline antimalarials. Scientific Reports, 8(1), https://doi.org/10.1038/s41598-018-20816-0

Antimalarial drug resistance hampers effective malaria treatment. Critical SNPs in a particular, putative amino acid transporter were recently linked to chloroquine (CQ) resistance in malaria parasites. Here, we show that this conserved protein (PF3D... Read More about Heterologous expression of a novel drug transporter from the malaria parasite alters resistance to quinoline antimalarials.

Microstructure and wear behaviour of powder and suspension hybrid Al2O3–YSZ coatings (2018)
Journal Article
Murray, J. W., Leva, A., Joshi, S., & Hussain, T. (in press). Microstructure and wear behaviour of powder and suspension hybrid Al2O3–YSZ coatings. Ceramics International, https://doi.org/10.1016/j.ceramint.2018.02.048

Suspension based plasma sprayed coatings can yield superior microstructural and tribological properties compared to conventional powder based plasma sprayed coatings. This study investigates a new hybrid method, using simultaneous spraying from powde... Read More about Microstructure and wear behaviour of powder and suspension hybrid Al2O3–YSZ coatings.

John Stuart Mill and Fourierism: ‘association’, ‘friendly rivalry’ and distributive justice (2018)
Journal Article
McCabe, H. (2018). John Stuart Mill and Fourierism: ‘association’, ‘friendly rivalry’ and distributive justice. Global Intellectual History, 4(1), 35-61. https://doi.org/10.1080/23801883.2018.1435983

John Stuart Mill’s self-description as ‘under the general designation of Socialist’ has been under-explored. It is an important feature of something else often overlooked: the importance of the French context of Mill’s thought. This article focuses... Read More about John Stuart Mill and Fourierism: ‘association’, ‘friendly rivalry’ and distributive justice.

Assessment of time-dependent density functional theory with the restricted excitation space approximation for excited state calculations of large systems (2018)
Journal Article
Hanson-Heine, M. W., George, M. W., & Besley, N. A. (in press). Assessment of time-dependent density functional theory with the restricted excitation space approximation for excited state calculations of large systems. Molecular Physics, 116(11), https://doi.org/10.1080/00268976.2018.1430388

The restricted excitation subspace approximation is explored as a basis to reduce the memory storage required in linear response time-dependent density functional theory (TDDFT) calculations within the Tamm-Dancoff approximation. It is shown that exc... Read More about Assessment of time-dependent density functional theory with the restricted excitation space approximation for excited state calculations of large systems.

PET-PANC: multicentre prospective diagnostic accuracy and health economic analysis study of the impact of combined modality 18fluorine-2-fluoro-2-deoxy-d-glucose positron emission tomography with computed tomography scanning in the diagnosis and management of pancreatic cancer (2018)
Journal Article
Ghaneh, P., Hanson, R., Titman, A., Lancaster, G., Plumpton, C., Lloyd-Williams, H., …Neoptolemos, J. P. (2018). PET-PANC: multicentre prospective diagnostic accuracy and health economic analysis study of the impact of combined modality 18fluorine-2-fluoro-2-deoxy-d-glucose positron emission tomography with computed tomography scanning in the diagnosis and management of pancreatic cancer. Health Technology Assessment, 22(7), 1-114. https://doi.org/10.3310/hta22070

Background: Pancreatic cancer diagnosis and staging can be difficult in 10–20% of patients. Positron emission tomography (PET)/computed tomography (CT) adds precise anatomical localisation to functional data. The use of PET/CT may add further value t... Read More about PET-PANC: multicentre prospective diagnostic accuracy and health economic analysis study of the impact of combined modality 18fluorine-2-fluoro-2-deoxy-d-glucose positron emission tomography with computed tomography scanning in the diagnosis and management of pancreatic cancer.

Impact of person-centered care training and person-centered activities on quality of life, agitation and antipsychotic use in people with dementia living in nursing homes: a cluster-randomized controlled trial of the WHELD intervention (2018)
Journal Article
Ballard, C., Corbett, A., Orrell, M., Williams, G., Moniz-Cook, E., Romeo, R., …Fossey, J. (2018). Impact of person-centered care training and person-centered activities on quality of life, agitation and antipsychotic use in people with dementia living in nursing homes: a cluster-randomized controlled trial of the WHELD intervention. PLoS Medicine, 15(2), Article e1002500. https://doi.org/10.1371/journal.pmed.1002500

Background: Agitation is a common, distressing and challenging symptom affecting large numbers of people with dementia and impacting significantly on quality of life (QoL). There is an urgent need for evidence-based, cost-effective psychosocial inter... Read More about Impact of person-centered care training and person-centered activities on quality of life, agitation and antipsychotic use in people with dementia living in nursing homes: a cluster-randomized controlled trial of the WHELD intervention.

Psychosocial factors associated with change in pain and disability outcomes in chronic low back pain patients treated by physiotherapist: a systematic review (2018)
Journal Article
Alhowimel, A., Alotaibi, M., Radford, K. A., & Coulson, N. S. (in press). Psychosocial factors associated with change in pain and disability outcomes in chronic low back pain patients treated by physiotherapist: a systematic review. SAGE Open Medicine, https://doi.org/10.1177/2050312118757387

Background: Almost 80% of people have low back pain at least once in their life. Clinical guidelines emphasize the use of conservative physiotherapy and the importance of staying active. While the psychological factors predicting poor recovery follow... Read More about Psychosocial factors associated with change in pain and disability outcomes in chronic low back pain patients treated by physiotherapist: a systematic review.

Period polynomials, derivatives of L-functions, and zerosof polynomials (2018)
Journal Article
Diamantis, N., & Rolen, L. (2018). Period polynomials, derivatives of L-functions, and zerosof polynomials. Research in the Mathematical Sciences, 5, Article 9. https://doi.org/10.1007/s40687-018-0126-4

Period polynomials have long been fruitful tools for the study of values of L-functions in the context of major outstanding conjectures. In this paper, we survey some facets of this study from the perspective of Eichler cohomology. We discuss ways to... Read More about Period polynomials, derivatives of L-functions, and zerosof polynomials.

Massive post-starburst galaxies at z > 1 are compact proto-spheroids (2018)
Preprint / Working Paper
Almaini, O., Wild, V., Maltby, D. T., Hartley, W. G., Simpson, C., Hatch, N. A., …Rowlands, K. Massive post-starburst galaxies at z > 1 are compact proto-spheroids

We investigate the relationship between the quenching of star formation and the structural transformation of massive galaxies, using a large sample of photometrically-selected post-starburst galaxies in the UKIDSS UDS field. We find that post-starbur... Read More about Massive post-starburst galaxies at z > 1 are compact proto-spheroids.

Interactions of C+(2PJ) with rare gas atoms: incipient chemical interactions, potentials and transport coefficients (2018)
Journal Article
Tuttle, W. D., Thorington, R. L., Viehland, L. A., Breckenridge, W., & Wright, T. G. (2018). Interactions of C+(2PJ) with rare gas atoms: incipient chemical interactions, potentials and transport coefficients. Philosophical Transactions A: Mathematical, Physical and Engineering Sciences, 376(2115), Article 20170156. https://doi.org/10.1098/rsta.2017.0156

Accurate interatomic potentials were calculated for the interaction of a singly charged carbon cation, C+, with a single rare gas atom, RG (RG = Ne–Xe). The RCCSD(T) method and basis sets of quadruple-ζ and quintuple-ζ quality were employed; each int... Read More about Interactions of C+(2PJ) with rare gas atoms: incipient chemical interactions, potentials and transport coefficients.