All Outputs (3102)

Comparison of the Structure and Activity of Glycosylated and Aglycosylated Human Carboxylesterase 1 (2015)
Journal Article
Arena de Souza, V., Scott, D. J., Nettleship, J. E., Rahman, N., Charlton, M. H., Walsh, M. A., & Owens, R. J. (2015). Comparison of the Structure and Activity of Glycosylated and Aglycosylated Human Carboxylesterase 1. PLoS ONE, 10(12), e0143919. https://doi.org/10.1371/journal.pone.0143919

Human Carboxylesterase 1 (hCES1) is the key liver microsomal enzyme responsible for detoxification and metabolism of a variety of clinical drugs. To analyse the role of the single N-linked glycan on the structure and activity of the enzyme, authentic... Read More about Comparison of the Structure and Activity of Glycosylated and Aglycosylated Human Carboxylesterase 1.

Comorbidities in patients with gout prior to and following diagnosis: case-control study (2015)
Journal Article
Kuo, C.-F., Grainge, M. J., Mallen, C., Zhang, W., & Doherty, M. (2016). Comorbidities in patients with gout prior to and following diagnosis: case-control study. Annals of the Rheumatic Diseases, 75(1), https://doi.org/10.1136/annrheumdis-2014-206410

OBJECTIVES: To determine the burden of comorbidities in patients with gout at diagnosis and the risk of developing new comorbidities post diagnosis. METHODS: There were 39 111 patients with incident gout and 39 111 matched controls identified fro... Read More about Comorbidities in patients with gout prior to and following diagnosis: case-control study.

Enacted Embodiment in Adaptive Architecture: Physiological Interactions Between Inhabitants and Biofeedback Architecture (2015)
Thesis
Jaeger, N. Enacted Embodiment in Adaptive Architecture: Physiological Interactions Between Inhabitants and Biofeedback Architecture. (Thesis). University of Nottingham. Retrieved from https://nottingham-repository.worktribe.com/output/4381761

This thesis argues for an enactive embodied approach to understanding interactions with Adaptive Architecture. The growing interest in Ubiquitous and Pervasive Computing, including the current trends of wearable, sensor infused technology, shows the... Read More about Enacted Embodiment in Adaptive Architecture: Physiological Interactions Between Inhabitants and Biofeedback Architecture.

Peace Operations Conducted by Regional Organizations and Arrangements (2015)
Book Chapter
White, N. D., & Myjer, E. P. (2015). Peace Operations Conducted by Regional Organizations and Arrangements. In T. D. Gill, & D. Fleck (Eds.), The Handbook of the International Law of Military Operations, 185-209. (Second). Oxford University Press

Loss mechanisms in high efficiency polymer solar cells (2015)
Journal Article
MacKenzie, R. C. I., Balderrama, V. S., Schmeisser, S., Stoof, R., Greedy, S., Pallarès, J., …von Hauff, E. (2016). Loss mechanisms in high efficiency polymer solar cells. Advanced Energy Materials, 6(4), 1-7. https://doi.org/10.1002/aenm.201501742

Performance losses and aging mechanisms are investigated in state‐of‐the‐art PTB7:PC70BM solar cells. Inverted devices incorporating a vanadium pentoxide (V2O5) top contact have efficiencies of 8%. After aging the unencapsulated devices, no changes a... Read More about Loss mechanisms in high efficiency polymer solar cells.

Wallerian degeneration is executed by an NMN-SARM1-dependent late Ca(2+) influx but only modestly influenced by mitochondria (2015)
Journal Article

Axon injury leads to rapid depletion of NAD-biosynthetic enzyme NMNAT2 and high levels of its substrate, NMN. We proposed a key role for NMN in Wallerian degeneration but downstream events and their relationship to other mediators remain unclear. Her... Read More about Wallerian degeneration is executed by an NMN-SARM1-dependent late Ca(2+) influx but only modestly influenced by mitochondria.

An adaptive RBF finite collocation approach to track transport processes across moving fronts (2015)
Journal Article
Power, H., Giddings, D., Jackson, S., & Stevens, D. (2016). An adaptive RBF finite collocation approach to track transport processes across moving fronts. Computers and Mathematics with Applications, 71(1), 278-300. https://doi.org/10.1016/j.camwa.2015.11.015

© 2015 Elsevier Ltd. We develop a radial basis function finite collocation method (RBF-FC) that utilises an adaptive quadtree dataset to cluster nodes around critical features in the domain, for the solution of transport processes occurring in moving... Read More about An adaptive RBF finite collocation approach to track transport processes across moving fronts.

Envy, Poison, and Death: Women on Trial in Classical Athens (2015)
Book
Eidinow, E. (2015). Envy, Poison, and Death: Women on Trial in Classical Athens. Oxford University Press. https://doi.org/10.1093/acprof%3Aoso/9780199562602.001.0001

At the heart of this book are some trials conducted in Athens in the fourth century BCE. In each case, the charges involved a combination of supernatural activities, including potion-brewing and cult activity; the defendants were all women. Because o... Read More about Envy, Poison, and Death: Women on Trial in Classical Athens.

Excess maternal salt or fructose intake programmes sex-specific, stress- and fructose-sensitive hypertension in the offspring (2015)
Journal Article
Gardiner, S. M., Gardner, D. S., Elmes, M., & Gray, C. (2016). Excess maternal salt or fructose intake programmes sex-specific, stress- and fructose-sensitive hypertension in the offspring. British Journal of Nutrition, 115(4), 594-604. https://doi.org/10.1017/S0007114515004936

© Copyright 2015 The Authors. The Western diet is typically high in salt and fructose, which have pressor activity. Maternal diet can affect offspring blood pressure, but the extent to which maternal intake of excess salt and fructose may influence c... Read More about Excess maternal salt or fructose intake programmes sex-specific, stress- and fructose-sensitive hypertension in the offspring.

A Century of Sea Level Measurements at Newlyn, Southwest England (2015)
Journal Article
Bradshaw, E., Woodworth, P., Hibbert, A., Bradley, L., Pugh, D., Fane, C., & Bingley, R. (2016). A Century of Sea Level Measurements at Newlyn, Southwest England. Marine Geodesy, 39(2), 115-140. https://doi.org/10.1080/01490419.2015.1121175

The Newlyn Tidal Observatory is the most important sea level station in the UK. It commenced operations in 1915 as part of the Second Geodetic Levelling of England and Wales, and the mean sea level determined from the tide gauge during the first six... Read More about A Century of Sea Level Measurements at Newlyn, Southwest England.

The effect of paratuberculosis on milk yield—a systematic review and meta-analysis (2015)
Journal Article
McAloon, C. G., Whyte, P., More, S. J., Green, M. J., O’Grady, L., Garcia, A., & Doherty, M. L. (2016). The effect of paratuberculosis on milk yield—a systematic review and meta-analysis. Journal of Dairy Science, 99(2), https://doi.org/10.3168/jds.2015-10156

Bovine paratuberculosis is a disease characterized by chronic granulomatous enteritis causing protein-losing enteropathy. Adverse effects on animal productivity are key drivers in the attempt to control paratuberculosis at the farm level. Economic mo... Read More about The effect of paratuberculosis on milk yield—a systematic review and meta-analysis.

Risk and protective factors for falls on stairs in young children: multicentre case–control study (2015)
Journal Article
Kendrick, D., Zou, K., Ablewhite, J., Watson, M., Coupland, C., Kay, B., …Reading, R. (2016). Risk and protective factors for falls on stairs in young children: multicentre case–control study. Archives of Disease in Childhood, 101(10), 909-916. https://doi.org/10.1136/archdischild-2015-308486

Aim: To investigate risk and protective factors for stair falls in children aged

Constraining the temperature–density relation of the intergalactic medium with the Lyman α and β forests (2015)
Journal Article
Boera, E., Murphy, M. T., Becker, G. D., & Bolton, J. S. (2016). Constraining the temperature–density relation of the intergalactic medium with the Lyman α and β forests. Monthly Notices of the Royal Astronomical Society, 456(1), L79-L83. https://doi.org/10.1093/mnrasl/slv172

The post-reionization thermal state of the intergalactic medium is characterized by a power-law relationship between temperature and density, with a slope determined by the parameter γ. We describe a new method to measure γ using the ratio of flux cu... Read More about Constraining the temperature–density relation of the intergalactic medium with the Lyman α and β forests.

Turnaround and failure: resource weaknesses and the rise and fall of Jarvis (2015)
Journal Article
Wild, A., & Locket, A. (2016). Turnaround and failure: resource weaknesses and the rise and fall of Jarvis. Business History, 58(6), 829-857. https://doi.org/10.1080/00076791.2015.1024229

Research employing the resource-based view (RBV) has overwhelming focused on the upside of resources, namely those that provide benefit to the firm. However, an emerging research stream suggests that the downside of resources, namely resource weaknes... Read More about Turnaround and failure: resource weaknesses and the rise and fall of Jarvis.

The provision of NHS health checks in a community setting: an ethnographic account (2015)
Journal Article
Riley, R., Coghill, N., Montgomery, A., Feder, G., & Horwood, J. (in press). The provision of NHS health checks in a community setting: an ethnographic account. BMC Health Services Research, 15, https://doi.org/10.1186/s12913-015-1209-1

Background: The UK National Health Service Health Checks programme aims to reduce avoidable cardiovascular deaths, disability and health inequalities in England. However, due to the reported lower uptake of screening in specific black and minority et... Read More about The provision of NHS health checks in a community setting: an ethnographic account.

Applying interval type-2 fuzzy rule based classifiers through a cluster-based class representation (2015)
Presentation / Conference Contribution
Navarro, J., Wagner, C., & Aickelin, U. (2015). Applying interval type-2 fuzzy rule based classifiers through a cluster-based class representation.

Fuzzy Rule-Based Classification Systems (FRBCSs) have the potential to provide so-called interpretable classifiers, i.e. classifiers which can be introspective, understood, validated and augmented by human experts by relying on fuzzy-set based rules.... Read More about Applying interval type-2 fuzzy rule based classifiers through a cluster-based class representation.

Cycling infrastructure for reducing cycling injuries in cyclists (2015)
Journal Article
Mulvaney, C. A., Smith, S., Watson, M. C., Parkin, J., Coupland, C., Miller, P., …McClintock, H. (2015). Cycling infrastructure for reducing cycling injuries in cyclists. Cochrane Database of Systematic Reviews, https://doi.org/10.1002/14651858.CD010415.pub2

Background: Cycling is an attractive form of transport. It is beneficial to the individual as a form of physical activity that may fit more readily into an individual’s daily routine, such as for cycling to work and to the shops, than other physical... Read More about Cycling infrastructure for reducing cycling injuries in cyclists.

Conceptualising cosmopolitan values in internationalised higher education: a capabilities approach (2015)
Presentation / Conference Contribution
Bridges, S. (2015). Conceptualising cosmopolitan values in internationalised higher education: a capabilities approach.

The increasingly internationalised nature of higher education has enhanced the potential for students to benefit from a more diverse student body, yet there are gaps between the rhetoric and ideals of internationalisation and the lived realities for... Read More about Conceptualising cosmopolitan values in internationalised higher education: a capabilities approach.

Urine tests for Down's syndrome screening (2015)
Journal Article
Alldred, S. K., Guo, B., Takwoingi, Y., Pennant, M., Wisniewski, S., Deeks, J. J., …Alldred, S. K. (2015). Urine tests for Down's syndrome screening. Cochrane Database of Systematic Reviews, https://doi.org/10.1002/14651858.CD011984

Background Down's syndrome occurs when a person has three copies of chromosome 21, or the specific area of chromosome 21 implicated in causing Down's syndrome, rather than two. It is the commonest congenital cause of mental disability and also lea... Read More about Urine tests for Down's syndrome screening.

Effect of aggregate gradation on the stiffness of asphalt mixtures (2015)
Journal Article
Al-Mosawe, H., Thom, N., Airey, G., & Ai-Bayati, A. (2015). Effect of aggregate gradation on the stiffness of asphalt mixtures. International Journal of Pavement Engineering and Asphalt Technology, 16(2), https://doi.org/10.1515/ijpeat-2015-0008

Aggregate gradation plays an important role in the behaviour of asphalt mixtures. Packing of aggregate is a very important factor that will be affected by changing the aggregate gradation. Many researchers have investigated different ways of describi... Read More about Effect of aggregate gradation on the stiffness of asphalt mixtures.