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Targeting RNA transcription and translation in ovarian cancer cells with pharmacological inhibitor CDKI-73 (2014)
Journal Article

Dysregulation of cellular transcription and translation is a fundamental hallmark of cancer. As CDK9 and Mnks play pivotal roles in the regulation of RNA transcription and protein synthesis, respectively, they are important targets for drug developme... Read More about Targeting RNA transcription and translation in ovarian cancer cells with pharmacological inhibitor CDKI-73.

Language description, prescription and usage in seventeenth-century German (2014)
Book Chapter
McLelland, N. (2014). Language description, prescription and usage in seventeenth-century German. In G. Rutten, R. Vosters, & W. Vandenbussche (Eds.), Norms and Usage in Language History, 1600–1900. A sociolinguistic and comparative perspective. Benjamins. https://doi.org/10.1075/ahs.3.11lel

This chapter examines the relationship between language prescription and language use in seventeenth-century German, reporting on a corpus investigation of the influence (or otherwise) of the leading grammarian Justus Georg Schottelius (1612–1676) on... Read More about Language description, prescription and usage in seventeenth-century German.

Human pro-social motivation and the maintenance of social order (2014)
Book Chapter
Gaechter, S. (2014). Human pro-social motivation and the maintenance of social order. The Oxford Handbook of Behavioral Economics and the Law. Oxford University Press. https://doi.org/10.1093/oxfordhb/9780199945474.013.0002

This chapter presents some insights from basic behavioral research on the role of human prosocial motivation to maintain social order. I argue that social order can be conceptualized as a public goods game. Past attempts to explain social order typic... Read More about Human pro-social motivation and the maintenance of social order.

Multiplexing Spheroid Volume, Resazurin and Acid Phosphatase Viability Assays for High-Throughput Screening of Tumour Spheroids and Stem Cell Neurospheres (2014)
Journal Article
Alexander, C., Ivanov, D. P., WALKER, D., Parker, T. L., GARNETT, M., Ashford, M. B., & Gellert, P. R. (2014). Multiplexing Spheroid Volume, Resazurin and Acid Phosphatase Viability Assays for High-Throughput Screening of Tumour Spheroids and Stem Cell Neurospheres. PLoS ONE, 9(8), Article e103817. https://doi.org/10.1371/journal.pone.0103817

Three-dimensional cell culture has many advantages over monolayer cultures, and spheroids have been hailed as the best current representation of small avascular tumours in vitro. However their adoption in regular screening programs has been hindered... Read More about Multiplexing Spheroid Volume, Resazurin and Acid Phosphatase Viability Assays for High-Throughput Screening of Tumour Spheroids and Stem Cell Neurospheres.

Reductions in Endocannabinoid Levels and Enhanced Coupling of Cannabinoid Receptors in the Striatum are Accompanied by Cognitive Impairments in the AβPPswe/PS1ΔE9 Mouse Model of Alzheimer's Disease (2014)
Journal Article
Maroof, N., Ravipati, S., Pardon, M. C., Barrett, D. A., & Kendall, D. A. (2014). Reductions in Endocannabinoid Levels and Enhanced Coupling of Cannabinoid Receptors in the Striatum are Accompanied by Cognitive Impairments in the AβPPswe/PS1ΔE9 Mouse Model of Alzheimer's Disease. Journal of Alzheimer's Disease, 42(1), 227-245. https://doi.org/10.3233/jad-131961

© 2014 - IOS Press and the authors. All rights reserved. Alterations in the endocannabinoid system (ECS) are thought to play a role in learning and memory impairments observed in Alzheimer's disease (AD). We aimed to determine the status of the brain... Read More about Reductions in Endocannabinoid Levels and Enhanced Coupling of Cannabinoid Receptors in the Striatum are Accompanied by Cognitive Impairments in the AβPPswe/PS1ΔE9 Mouse Model of Alzheimer's Disease.

Stallone and Hollywood in Transition (2014)
Book Chapter
Gallagher, M. (2014). Stallone and Hollywood in Transition. In C. Holmlund (Ed.), The Ultimate Stallone Reader, 97-119. Columbia University Press

The ‘Swallow Tail’ Appearance of the Healthy Nigrosome – A New Accurate Test of Parkinson's Disease: A Case-Control and Retrospective Cross-Sectional MRI Study at 3T (2014)
Journal Article
Schwarz, S., Afzal, M., Morgan, P., Auer, D., Bajaj, N., & Gowland, P. A. (2014). The ‘Swallow Tail’ Appearance of the Healthy Nigrosome – A New Accurate Test of Parkinson's Disease: A Case-Control and Retrospective Cross-Sectional MRI Study at 3T. PLoS ONE, 9(4), Article e93814. https://doi.org/10.1371/journal.pone.0093814

There is no well-established in vivo marker of nigral degeneration in Parkinson's disease (PD). An ideal imaging marker would directly mirror the loss of substantia nigra dopaminergic neurones, which is most prominent in sub-regions called nigrosomes... Read More about The ‘Swallow Tail’ Appearance of the Healthy Nigrosome – A New Accurate Test of Parkinson's Disease: A Case-Control and Retrospective Cross-Sectional MRI Study at 3T.

Exceptional gravimetric and volumetric hydrogen storage for densified zeolite templated carbons with high mechanical stability (2014)
Journal Article
Mokaya, R., & Masika, E. (2014). Exceptional gravimetric and volumetric hydrogen storage for densified zeolite templated carbons with high mechanical stability. Energy and Environmental Science, 7(1), 427-434. https://doi.org/10.1039/c3ee42239a

Zeolite templating successfully generates carbons with high surface area and pore volume of ca. 3300 m2 g−1 and 1.6 cm3 g−1, respectively. The templated carbons have an exceptional gravimetric hydrogen uptake of 7.3 wt% at 20 bar and −196 °C, and a p... Read More about Exceptional gravimetric and volumetric hydrogen storage for densified zeolite templated carbons with high mechanical stability.