Glial activation in the early stages of brain metastasis: TSPO as a diagnostic biomarker

ER, O'Brien; Serres, S�bastien; V, Kersemans; M, Tredwell; B, Checa; MS, Soto; V, Gouverneur; D, Leppert; DC, Anthony; NR., Sibson

doi:10.2967/jnumed.113.127449

All Outputs (3)

ASPP2 controls epithelial plasticity and inhibits metastasis through β-catenin-dependent regulationofZEB1 (2014)
Journal Article
Wang, Y., SERRES, S., Bu, F., Royer, C., Larkin, J. R., Sarmiento Soto, M., …Lu, X. (2014). ASPP2 controls epithelial plasticity and inhibits metastasis through β-catenin-dependent regulationofZEB1. Nature Cell Biology, 16(11), 1092-1104. https://doi.org/10.1038/ncb3050

T(2)-weighted MRI detects presymptomatic pathology in the SOD1 mouse model of ALS (2014)
Journal Article

Neuroinflammation has been identified as a potential therapeutic target in amyotrophic lateral sclerosis (ALS), but relevant biomarkers are needed. The superoxide dismutase (SOD1)G93A transgenic mouse model of ALS offers a unique opportunity to study... Read More about T(2)-weighted MRI detects presymptomatic pathology in the SOD1 mouse model of ALS.

Glial activation in the early stages of brain metastasis: TSPO as a diagnostic biomarker (2014)
Journal Article
ER, O., Serres, S., V, K., M, T., B, C., MS, S., …NR., S. (2014). Glial activation in the early stages of brain metastasis: TSPO as a diagnostic biomarker. Journal of Nuclear Medicine, 55(2), 275-280. https://doi.org/10.2967/jnumed.113.127449

Metastatic spread of cancer cells to the brain is associated with high mortality, primarily because current diagnostic tools identify only well-advanced metastases. Brain metastases have been shown to induce a robust glial response, including both as... Read More about Glial activation in the early stages of brain metastasis: TSPO as a diagnostic biomarker.