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Farm systems assessment of bioenergy feedstock production: Integrating bio-economic models and life cycle analysis approaches (2012)
Journal Article
Glithero, N., Ramsden, S., & Wilson, P. (2012). Farm systems assessment of bioenergy feedstock production: Integrating bio-economic models and life cycle analysis approaches. Agricultural Systems, 109, https://doi.org/10.1016/j.agsy.2012.02.005

Climate change and energy security concerns have driven the development of policies that encourage bioenergy production. Meeting EU targets for the consumption of transport fuels from bioenergy by 2020 will require a large increase in the production... Read More about Farm systems assessment of bioenergy feedstock production: Integrating bio-economic models and life cycle analysis approaches.

Variation among individual dairy cows in methane measurements made on farm during milking (2012)
Journal Article
Garnsworthy, P., Craigon, J., Hernandez-Medrano, J., & Saunders, N. (2012). Variation among individual dairy cows in methane measurements made on farm during milking. Journal of Dairy Science, 95(6), https://doi.org/10.3168/jds.2011-4606

The objective of this study was to quantify on-farm variation between and within cows in methane emissions measured during milking, and to determine which factors are related to this variation. Methane emission rate during milking (MERm) was recorded... Read More about Variation among individual dairy cows in methane measurements made on farm during milking.

On-farm methane measurements during milking correlate with total methane production by individual dairy cows (2012)
Journal Article
Garnsworthy, P., Craigon, J., Hernandez-Medrano, J., & Saunders, N. (2012). On-farm methane measurements during milking correlate with total methane production by individual dairy cows. Journal of Dairy Science, 95(6), https://doi.org/10.3168/jds.2011-4605

The objective of this study was to investigate whether measurement of methane emissions by individual dairy cows during milking could provide a useful technique for monitoring on-farm methane emissions. To quantify methane emissions from individual c... Read More about On-farm methane measurements during milking correlate with total methane production by individual dairy cows.

Action of linezolid or vancomycin on biofilms in ventriculoperitoneal shunts in vitro (2012)
Journal Article
Bayston, R., Ullas, G., & Ashraf, W. (2012). Action of linezolid or vancomycin on biofilms in ventriculoperitoneal shunts in vitro. Antimicrobial Agents and Chemotherapy, 56(6), https://doi.org/10.1128/AAC.06326-11

Cerebrospinal fluid (CSF) shunts used to treat hydrocephalus have an overall infection rate of about 10% of operations. The commonest causative bacteria are Staphylococcus epidermidis, followed by Staphylococcus aureus and enterococci. Major difficul... Read More about Action of linezolid or vancomycin on biofilms in ventriculoperitoneal shunts in vitro.

Deflection and frequency monitoring of the Forth Road Bridge, Scotland, by GPS (2012)
Journal Article
Roberts, G. W., Brown, C. J., Meng, X., Ogundipe, O., Atkins, C., & Colford, B. (2012). Deflection and frequency monitoring of the Forth Road Bridge, Scotland, by GPS. Proceedings of the ICE - Bridge Engineering, 165(2), https://doi.org/10.1680/bren.9.00022

The use of carrier phase kinematic GPS (global positioning system) has evolved into a reliable technique to measure both the three-dimensional magnitudes and frequencies of movements of structures. Techniques have been developed that tackle errors ca... Read More about Deflection and frequency monitoring of the Forth Road Bridge, Scotland, by GPS.

A model of management academics' intentions to influence values (2012)
Journal Article
Moosmayer, D. C. (2012). A model of management academics' intentions to influence values. Academy of Management Learning and Education, 11(2), https://doi.org/10.5465/amle.2010.0053

Business schools face increased criticism for failing in the teaching of management studies to nurture their students’ values. Assuming that individual academics play an important role in shaping the value-related influence of business schools, I mod... Read More about A model of management academics' intentions to influence values.

Jacques Monod, François Jacob, and the Lysenko affair: boundary work (2012)
Journal Article
Marks, J. (2012). Jacques Monod, François Jacob, and the Lysenko affair: boundary work. Esprit Créateur, 52(2), https://doi.org/10.1353/esp.2012.0020

This article looks at the highly influential scientific work of François Jacob and Jacques Monod in the context of the Lysenko affair. It argues that Lysenkoism provided a stimulus to understand and interpret the science they were doing in the field... Read More about Jacques Monod, François Jacob, and the Lysenko affair: boundary work.

Vru (Sub0144) controls expression of proven and putative virulence determinants and alters the ability of Streptococcus uberis to cause disease in dairy cattle (2012)
Journal Article
Egan, S. A., Ward, P. N., Watson, M., Field, T. R., & Leigh, J. A. (in press). Vru (Sub0144) controls expression of proven and putative virulence determinants and alters the ability of Streptococcus uberis to cause disease in dairy cattle. Microbiology, 158, https://doi.org/10.1099/mic.0.055863-0

The regulation and control of gene expression in response to differing environmental stimuli is crucial for successful pathogen adaptation and persistence. The regulatory gene vru of Streptococcus uberis encodes a stand-alone response regulator with... Read More about Vru (Sub0144) controls expression of proven and putative virulence determinants and alters the ability of Streptococcus uberis to cause disease in dairy cattle.

Effect of colon cancer and surgical resection on skeletal muscle mitochondrial enzyme activity in colon cancer patients: a pilot study (2012)
Journal Article
Phillips, B. E., Smith, K., Liptrot, S., Atherton, P. J., Varadhan, K., Rennie, M. J., …Williams, J. P. (2013). Effect of colon cancer and surgical resection on skeletal muscle mitochondrial enzyme activity in colon cancer patients: a pilot study. Journal of Cachexia, Sarcopenia and Muscle, 4(1), 71-77. https://doi.org/10.1007/s13539-012-0073-7

The effect of intergalactic helium on hydrogen reionization: implications for the sources of ionizing photons at z>6 (2012)
Journal Article
Ciardi, B., Bolton, J., Maselli, A., & Graziani, L. (2012). The effect of intergalactic helium on hydrogen reionization: implications for the sources of ionizing photons at z>6. Monthly Notices of the Royal Astronomical Society, 423(1), 558-574. https://doi.org/10.1111/j.1365-2966.2012.20902.x

We investigate the effect of primordial helium on hydrogen reionization using a hydrodynamical simulation combined with the cosmological radiative transfer code CRASH. The radiative transfer simulations are performed in a 35.12 h−1 comoving Mpc box u... Read More about The effect of intergalactic helium on hydrogen reionization: implications for the sources of ionizing photons at z>6.

Three-dimensional pharmacophore design and biochemical screening identifies substituted 1,2,4-triazoles as inhibitors of the annexin A2-S100A10 protein interaction (2012)
Journal Article
Reddy, T. R., Li, C., Fischer, P. M., & Dekker, L. V. (2012). Three-dimensional pharmacophore design and biochemical screening identifies substituted 1,2,4-triazoles as inhibitors of the annexin A2-S100A10 protein interaction. ChemMedChem, 7(8), https://doi.org/10.1002/cmdc.201200107

Protein interactions are increasingly appreciated as targets in small-molecule drug discovery. The interaction between the adapter protein S100A10 and its binding partner annexin A2 is a potentially important drug target. To obtain small-molecule sta... Read More about Three-dimensional pharmacophore design and biochemical screening identifies substituted 1,2,4-triazoles as inhibitors of the annexin A2-S100A10 protein interaction.

Evidence of past environmental conditions during the evolution of a calcretised Wadi System in Southern Jordan using stable isotopes (2012)
Journal Article
McLaren, S. J., Leng, M. J., Knowles, T., & Bradley, A. V. (2012). Evidence of past environmental conditions during the evolution of a calcretised Wadi System in Southern Jordan using stable isotopes. Palaeogeography, Palaeoclimatology, Palaeoecology, 348-349, 1-12. https://doi.org/10.1016/j.palaeo.2012.05.010

A stratigraphically and temporally ordered sequence of channel calcretes preserved along the Wadi Dana, Southern Jordan, records the Quaternary evolution of the formation and infilling of rock-cut channels and their subsequent incision in a tectonica... Read More about Evidence of past environmental conditions during the evolution of a calcretised Wadi System in Southern Jordan using stable isotopes.

Self-tuning and the derivation of a class of scalar-tensor theories (2012)
Journal Article
Charmousis, C., Copeland, E. J., Padilla, A., & Saffin, P. M. (2012). Self-tuning and the derivation of a class of scalar-tensor theories. Physical Review D, 85(10), Article 104040. https://doi.org/10.1103/PhysRevD.85.104040

We have recently proposed a special class of scalar tensor theories known as the Fab Four. These arose from attempts to analyse the cosmological constant problem within the context of Horndeski's most general scalar tensor theory. The Fab Four togeth... Read More about Self-tuning and the derivation of a class of scalar-tensor theories.

A prospective cross-screening study on G-protein-coupled receptors: lessons learned in virtual compound library design. (2012)
Journal Article
Sanders, M. P. A., Roumen, L., van der Horst, E., Lane, J. R., Vischer, H. F., van Offenbeek, J., de Vries, H., Verhoeven, S., Chow, K. Y., Verkaar, F., Beukers, M. W., McGuire, R., Leurs, R., Ijzerman, A. P., de Vlieg, J., de Esch, I. J. P., Zaman, G. J. R., Klomp, J. P. G., Bender, A., & de Graaf, C. (2012). A prospective cross-screening study on G-protein-coupled receptors: lessons learned in virtual compound library design. Journal of Medicinal Chemistry, 55(11), 5311-5325. https://doi.org/10.1021/jm300280e

We present the systematic prospective evaluation of a protein-based and a ligand-based virtual screening platform against a set of three G-protein-coupled receptors (GPCRs): the β-2 adrenoreceptor (ADRB2), the adenosine A(2A) receptor (AA2AR), and th... Read More about A prospective cross-screening study on G-protein-coupled receptors: lessons learned in virtual compound library design..

Strategies for MCR image analysis of large hyperspectral data-sets (2012)
Journal Article
Scurr, D. J., Hook, A. L., Burley, J., Williams, P. M., Anderson, D. G., Langer, R., …Alexander, M. R. (2012). Strategies for MCR image analysis of large hyperspectral data-sets. Surface and Interface Analysis, 45(1), https://doi.org/10.1002/sia.5040

Polymer microarrays are a key enabling technology for high throughput materials discovery. In this study, multivariate image analysis, specifically multivariate curve resolution (MCR), is applied to the hyperspectral time of flight secondary ion mass... Read More about Strategies for MCR image analysis of large hyperspectral data-sets.