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Mapping the laminin receptor binding domains of Neisseria meningitidis PorA and Haemophilus influenzae OmpP2 (2012)
Journal Article
Abouseada, N. M., Assafi, M. S. A., Mahdavi, J., Oldfield, N. J., Wheldon, L. M., Wooldridge, K. G., & Ala'Aldeen, D. A. (2012). Mapping the laminin receptor binding domains of Neisseria meningitidis PorA and Haemophilus influenzae OmpP2. PLoS ONE, 7(9), Article 10. https://doi.org/10.1371/journal.pone.0046233

Neisseria meningitidis, Haemophilus influenzae and Streptococcus pneumoniae are major bacterial agents of meningitis. They each bind the 37/67-kDa laminin receptor (LamR) via the surface protein adhesins: meningococcal PilQ and PorA, H. influenzae Om... Read More about Mapping the laminin receptor binding domains of Neisseria meningitidis PorA and Haemophilus influenzae OmpP2.

Why are family carers of people with dementia dissatisfied with general hospital care?: a qualitative study (2012)
Journal Article
Jurgens, F. J., Clissett, P., Gladman, J. R., & Harwood, R. H. (2012). Why are family carers of people with dementia dissatisfied with general hospital care?: a qualitative study. BMC Geriatrics, 12(57), Article 1. https://doi.org/10.1186/1471-2318-12-57

Background Families and other carers report widespread dissatisfaction with general hospital care for confused older people. Methods We undertook a qualitative interviews study of 35 family carers of 34 confused older patients to ascertain their... Read More about Why are family carers of people with dementia dissatisfied with general hospital care?: a qualitative study.

Why is the Liverpool care pathway used for some dying cancer patients and not others? Healthcare professionals’ perspectives (2012)
Journal Article
Freemantle, A., & Seymour, J. (2012). Why is the Liverpool care pathway used for some dying cancer patients and not others? Healthcare professionals’ perspectives. BMC Research Notes, 5(524), https://doi.org/10.1186/1756-0500-5-524

Background: Despite evidence suggesting that the Liverpool Care Pathway for the Dying Patient is a structured and proficient means of supporting care delivery in the last hours or days of life, discrepancies in uptake are widespread. This explorator... Read More about Why is the Liverpool care pathway used for some dying cancer patients and not others? Healthcare professionals’ perspectives.

Regulation of Anopheles gambiae male accessory gland genes influences postmating response in female (2012)
Journal Article
Dottorini, T., Persampieri, T., Palladino, P., Baker, D. A., Spaccapelo, R., Senin, N., & Crisanti, A. (2013). Regulation of Anopheles gambiae male accessory gland genes influences postmating response in female. FASEB Journal, 27(1), 86-97. https://doi.org/10.1096/fj.12-219444

In Drosophila, the accessory gland proteins (Acps) secreted from the male accessory glands (MAGs) and transferred along with sperm into the female reproductive tract have been implicated in triggering postmating behavioral changes, including refracto... Read More about Regulation of Anopheles gambiae male accessory gland genes influences postmating response in female.

A unique protein phosphatase with kelch-like domains (PPKL) in plasmodium modulates ookinete differentiation, motility and invasion (2012)
Journal Article
Guttery, D. S., Poulin, B., Ferguson, D. J. P., Szöőr, B., Wickstead, B., Carroll, P. L., …Tewari, R. (2012). A unique protein phosphatase with kelch-like domains (PPKL) in plasmodium modulates ookinete differentiation, motility and invasion. PLoS Pathogens, 8(9), Article e1002948. https://doi.org/10.1371/journal.ppat.1002948

Protein phosphorylation and dephosphorylation (catalysed by kinases and phosphatases, respectively) are post-translational modifications that play key roles in many eukaryotic signalling pathways, and are often deregulated in a number of pathological... Read More about A unique protein phosphatase with kelch-like domains (PPKL) in plasmodium modulates ookinete differentiation, motility and invasion.

A cooperative instinct (2012)
Journal Article
Gaechter, S. (2012). A cooperative instinct. Nature, 489(7416), https://doi.org/10.1038/489374a

Acting on a gut feeling may sometimes lead to poor decisions, but it will usually support the common good, according to a study showing that human intuition favours cooperative, rather than selfish, behaviour.

Coping with and factors impacting upon the experience of lung cancer in patients and primary carers (2012)
Journal Article
Ellis, J., Lloyd-williams, M., Wagland, R., Bailey, C., & Molassiotis, A. (in press). Coping with and factors impacting upon the experience of lung cancer in patients and primary carers. European Journal of Cancer Care, 22(1), https://doi.org/10.1111/ecc.12003

There is a paucity of research exploring patients' and their informal carers' experience of coping with and factors impacting on the lung cancer experience. This study aims to explore how patients and their informal carers cope with a diagnosis of lu... Read More about Coping with and factors impacting upon the experience of lung cancer in patients and primary carers.

A Bayesian elicitation of veterinary beliefs regarding systemic dry cow therapy: variation and importance for clinical trial design (2012)
Journal Article
Higgins, H., Dryden, I. L., & Green, M. J. (2012). A Bayesian elicitation of veterinary beliefs regarding systemic dry cow therapy: variation and importance for clinical trial design. Preventive Veterinary Medicine, 106(2), https://doi.org/10.1016/j.prevetmed.2012.01.017

The two key aims of this research were: (i) to conduct a probabilistic elicitation to quantify the variation in veterinarians’ beliefs regarding the efficacy of systemic antibiotics when used as an adjunct to intra-mammary dry cow therapy and (ii) to... Read More about A Bayesian elicitation of veterinary beliefs regarding systemic dry cow therapy: variation and importance for clinical trial design.

The essential iron-sulfur protein Rli1 is an important target accounting for inhibition of cell growth by reactive oxygen species (2012)
Journal Article
Alhebshi, A., Sideri, T. C., Holland, S. L., & Avery, S. V. (2012). The essential iron-sulfur protein Rli1 is an important target accounting for inhibition of cell growth by reactive oxygen species. Molecular Biology of the Cell, 23(18), https://doi.org/10.1091/mbc.E12-05-0413

Oxidative stress mediated by reactive oxygen species (ROS) is linked to degenerative conditions in humans and damage to an array of cellular components. However, it is unclear which molecular target(s) may be the primary “Achilles’ heel” of organisms... Read More about The essential iron-sulfur protein Rli1 is an important target accounting for inhibition of cell growth by reactive oxygen species.

The impact of individual budgets on the targeting of support: Findings from a national evaluation of pilot projects in England (2012)
Journal Article
Jones, K., Netten, A., Fernández, J. L., Knapp, M., Challis, D., Glendinning, C., …Wilberforce, M. (2012). The impact of individual budgets on the targeting of support: Findings from a national evaluation of pilot projects in England. Public Money and Management, 32(6), 417-424. https://doi.org/10.1080/09540962.2012.728781

Individual or personal budgets are part of a growing international trend to encourage greater choice and control over social care services at a time of financial austerity. The authors' evaluation of individual budgets found that levels of allocated... Read More about The impact of individual budgets on the targeting of support: Findings from a national evaluation of pilot projects in England.

The linear spin-up of a stratified, rotating fluid in a square cylinder (2012)
Journal Article
Foster, M., & Munro, R. J. (2012). The linear spin-up of a stratified, rotating fluid in a square cylinder. Journal of Fluid Mechanics, 712, https://doi.org/10.1017/jfm.2012.402

Here we present experimental and theoretical results for how a stratified fluid, initially rotating as a solid body with constant angular velocity, , within a closed cylinder of square cross-section, is spun up when subject to a small, impulsive incr... Read More about The linear spin-up of a stratified, rotating fluid in a square cylinder.

Demographics and economic burden of un-owned cats and dogs in the UK: results of a 2010 census (2012)
Journal Article
Stavisky, J., Brennan, M. L., Downes, M. J., & Dean, R. S. (2012). Demographics and economic burden of un-owned cats and dogs in the UK: results of a 2010 census. BMC Veterinary Research, 8, Article 163. https://doi.org/10.1186/1746-6148-8-163

Background The population of dogs and cats passing through rescue shelters may be subject to compromised welfare and increased susceptibility to disease. Little information exists to describe this population, its dynamics and associated management... Read More about Demographics and economic burden of un-owned cats and dogs in the UK: results of a 2010 census.

Protocol evaluating the effectiveness of a school-based group programme for parents of children at risk of ADHD: the ‘PArents, Teachers and CHildren WORKing Together (PATCHWORK)’ cluster RCT protocol (2012)
Journal Article
Sayal, K., Daley, D., James, M., Yang, M., Batty, M. J., Taylor, J. A., …Hollis, C. (2012). Protocol evaluating the effectiveness of a school-based group programme for parents of children at risk of ADHD: the ‘PArents, Teachers and CHildren WORKing Together (PATCHWORK)’ cluster RCT protocol. BMJ Open, 2(5), Article e001783. https://doi.org/10.1136/bmjopen-2012-001783

Introduction Early intervention for childhood behavioural problems may help improve health and educational outcomes in affected children and reduce the likelihood of developing additional difficulties. The National Institute for Health and Clinical... Read More about Protocol evaluating the effectiveness of a school-based group programme for parents of children at risk of ADHD: the ‘PArents, Teachers and CHildren WORKing Together (PATCHWORK)’ cluster RCT protocol.

Advanced geometry modelling of 3D woven reinforcements in polymer composites: processing and performance analysis (2012)
Presentation / Conference Contribution
Zeng, X., Brown, L. P., Endruweit, A., & Long, A. C. (2012). Advanced geometry modelling of 3D woven reinforcements in polymer composites: processing and performance analysis.

Numerical methods have become increasingly effective tools for analysis and design of composite materials. This study investigates how the inclusion of geometrical variations in modelling 3D woven fabrics affects the accuracy of numerical predictions... Read More about Advanced geometry modelling of 3D woven reinforcements in polymer composites: processing and performance analysis.

Efficient online subspace learning with an indefinite kernel for visual tracking and recognition (2012)
Journal Article
Liwicki, S., Zafeiriou, S., Tzimiropoulos, G., & Pantic, M. (2012). Efficient online subspace learning with an indefinite kernel for visual tracking and recognition. IEEE Transactions on Neural Networks and Learning Systems, 23(10), https://doi.org/10.1109/TNNLS.2012.2208654

We propose an exact framework for online learning with a family of indefinite (not positive) kernels. As we study the case of nonpositive kernels, we first show how to extend kernel principal component analysis (KPCA) from a reproducing kernel Hilber... Read More about Efficient online subspace learning with an indefinite kernel for visual tracking and recognition.

Calpain system protein expression in basal-like and triple-negative invasive breast cancer (2012)
Journal Article
Storr, S. J., Lee, K., Woolston, C. M., Safuan, S., Green, A., Macmillan, R., …Martin, S. G. (2012). Calpain system protein expression in basal-like and triple-negative invasive breast cancer. Annals of Oncology, 23(9), https://doi.org/10.1093/annonc/mds176

Background: Basal-like and triple-negative breast tumours encompass an important clinical subgroup and biomarkers that can prognostically stratify these patients are required. Materials and methods: We investigated two breast cancer tissue microarr... Read More about Calpain system protein expression in basal-like and triple-negative invasive breast cancer.

Increased Responses to the Actions of Fibroblast Growth Factor 21 on Energy Balance and Body Weight in a Seasonal Model of Adiposity (2012)
Journal Article
Murphy, M., Samms, R., Warner, A., Bolborea, M., Barrett, P., Fowler, M. J., …Ebling, F. J. (2013). Increased Responses to the Actions of Fibroblast Growth Factor 21 on Energy Balance and Body Weight in a Seasonal Model of Adiposity. Journal of Neuroendocrinology, 25(2), 180-189. https://doi.org/10.1111/j.1365-2826.2012.02383.x

The present study aimed to investigate the actions of fibroblast growth factor 21 (FGF21) on energy balance in a natural model of relative fatness, the Siberian hamster. Hamsters were studied under long days (LD) to promote weight gain, or short days... Read More about Increased Responses to the Actions of Fibroblast Growth Factor 21 on Energy Balance and Body Weight in a Seasonal Model of Adiposity.