Protocol for a qualitative study exploring the roles of ‘Diffusion Fellows’ in bridging the research to practice gap in the Nottinghamshire, Derbyshire and Lincolnshire Collaboration for Leadership in Applied Health Research and Care (CLAHRC-NDL)
(2012)
Journal Article
Rowley, E. (2012). Protocol for a qualitative study exploring the roles of ‘Diffusion Fellows’ in bridging the research to practice gap in the Nottinghamshire, Derbyshire and Lincolnshire Collaboration for Leadership in Applied Health Research and Care (CLAHRC-NDL). BMJ Open, 2(1), Article e000604. https://doi.org/10.1136/bmjopen-2011-000604
All Outputs (672)
The role of genetics in pre-eclampsia and potential pharmacogenomic interventions (2012)
Journal Article
Williams, P. J., & Morgan, L. (2012). The role of genetics in pre-eclampsia and potential pharmacogenomic interventions. Pharmacogenomics and Personalized Medicine, 2012:5, https://doi.org/10.2147/PGPM.S23141The pregnancy-specific condition pre-eclampsia not only affects the health of mother and baby during pregnancy but also has long-term consequences, increasing the chances of cardiovascular disease in later life. It is accepted that pre-eclampsia has... Read More about The role of genetics in pre-eclampsia and potential pharmacogenomic interventions.
Subspace learning from image gradient orientations (2012)
Journal Article
Tzimiropoulos, G., Zafeiriou, S., & Pantic, M. (2012). Subspace learning from image gradient orientations. IEEE Transactions on Pattern Analysis and Machine Intelligence, 34(12), 2454-2466. https://doi.org/10.1109/TPAMI.2012.40We introduce the notion of subspace learning from image gradient orientations for appearance-based object recognition. As image data is typically noisy and noise is substantially different from Gaussian, traditional subspace learning from pixel inten... Read More about Subspace learning from image gradient orientations.
‘Appropriate’ medical treatment: what’s in a word? (2012)
Journal Article
Phull, J., & Bartlett, P. (2012). ‘Appropriate’ medical treatment: what’s in a word?. Medicine, Science and the Law, https://doi.org/10.1258/msl.2011.011023Following the amendments in the 2007 Act, there were several revisions made focusing largely on community treatment orders and deprivation of liberty of persons lacking capacity. One of the amendments included a requirement that ‘appropriate treatmen... Read More about ‘Appropriate’ medical treatment: what’s in a word?.
Integration of DNA into bacterial chromosomes from plasmids without a counter-selection marker (2012)
Journal Article
Heap, J. T., Ehsaan, M., Cooksley, C. M., Ng, Y., Cartman, S. T., Winzer, K., & Minton, N. P. (2012). Integration of DNA into bacterial chromosomes from plasmids without a counter-selection marker. Nucleic Acids Research, 40(8), Article 10. https://doi.org/10.1093/nar/gkr1321Most bacteria can only be transformed with circular plasmids, so robust DNA integration methods for these rely upon selection of single-crossover clones followed by counter-selection of double-crossover clones. To overcome the limited availability of... Read More about Integration of DNA into bacterial chromosomes from plasmids without a counter-selection marker.
Fluoxetine counteracts the cognitive and cellular effects of 5-Fluorouracil in the rat hippocampus by a mechanism of prevention rather than recovery (2012)
Journal Article
Lyons, L., ELBeltagy, M., Bennett, G., & Wigmore, P. (2012). Fluoxetine counteracts the cognitive and cellular effects of 5-Fluorouracil in the rat hippocampus by a mechanism of prevention rather than recovery. PLoS ONE, 7(1), Article e30010. https://doi.org/10.1371/journal.pone.00300105-Fluorouracil (5-FU) is a cytostatic drug associated with chemotherapy-induced cognitive impairments that many cancer
patients experience after treatment. Previous work in rodents has shown that 5-FU reduces hippocampal cell proliferation, a
possi... Read More about Fluoxetine counteracts the cognitive and cellular effects of 5-Fluorouracil in the rat hippocampus by a mechanism of prevention rather than recovery.
Hans Christoph Buch’s Sansibar Blues and the fascination of cross-cultural experience in contemporary German historical novels about colonialism (2012)
Journal Article
Göttsche, D. (2012). Hans Christoph Buch’s Sansibar Blues and the fascination of cross-cultural experience in contemporary German historical novels about colonialism. German Life and Letters, 65(1), https://doi.org/10.1111/j.1468-0483.2011.01563.xThis article maps four different types of cross-cultural experience in contemporary historical novels about colonial Africa (colonialist, exoticist, intercultural, and transcultural) before focusing on Buch’s Sansibar Blues (2008) as a case study in... Read More about Hans Christoph Buch’s Sansibar Blues and the fascination of cross-cultural experience in contemporary German historical novels about colonialism.
Ball and rackets: inferring fiber fanning from diffusion-weighted MRI (2012)
Journal Article
Sotiropoulos, S. N., Behrens, T. E., & Jbabdi, S. (2012). Ball and rackets: inferring fiber fanning from diffusion-weighted MRI. NeuroImage, 60(2), https://doi.org/10.1016/j.neuroimage.2012.01.056A number of methods have been proposed for resolving crossing fibers from diffusion-weighted (DW) MRI. However, other complex fiber geometries have drawn minimal attention. In this study, we focus on fiber orientation dispersion induced by within-vox... Read More about Ball and rackets: inferring fiber fanning from diffusion-weighted MRI.
Exposure to bisphosphonates and risk of cancer: a protocol for nested caseecontrol studies using the QResearch primary care database (2012)
Journal Article
Vinogradova, Y., Coupland, C., & Hippisley-Cox, J. (2012). Exposure to bisphosphonates and risk of cancer: a protocol for nested caseecontrol studies using the QResearch primary care database. BMJ Open, 2(1), Article e000548. https://doi.org/10.1136/bmjopen-2011-000548Introduction: Bisphosphonates are becoming
a common treatment for osteoporosis particularly after
discovery of the association between hormone
replacement therapy and increased risk of breast
cancer. As osteoporosis develops with age, treatment... Read More about Exposure to bisphosphonates and risk of cancer: a protocol for nested caseecontrol studies using the QResearch primary care database.
Hemispheric dispersion of radioactive plume laced with fission nuclides from the Fukushima nuclear event (2012)
Journal Article
Hsu, S., Huh, C., Chan, C., Lin, S., Lin, F., & Liu, S. C. (2012). Hemispheric dispersion of radioactive plume laced with fission nuclides from the Fukushima nuclear event. Geophysical Research Letters, 39(7), https://doi.org/10.1029/2011GL049986Radioactivities of particulate 131I and 137Cs released from the Fukushima nuclear accident were monitored in a regional aerosol network including two high mountain sites (central Taiwan and Tibetan Plateau). The results were integrated with data meas... Read More about Hemispheric dispersion of radioactive plume laced with fission nuclides from the Fukushima nuclear event.
Quantization of the massive gravitino on FRW spacetimes (2012)
Journal Article
Schenkel, A., & F. Uhlemann, C. (2012). Quantization of the massive gravitino on FRW spacetimes. Physical Review D - Particles, Fields, Gravitation and Cosmology, 85(2), Article 024011. https://doi.org/10.1103/PhysRevD.85.024011In this article we study the quantization and causal properties of a massive spin 3/2 Rarita-Schwinger field on spatially flat Friedmann-Robertson-Walker (FRW) spacetimes. We construct Zuckerman's universal conserved current and prove that it leads t... Read More about Quantization of the massive gravitino on FRW spacetimes.
Negotiating left-hand and right-hand bends: a motorcycle simulator study to investigate experiential and behaviour differences across rider groups (2012)
Journal Article
Crundall, E., Crundall, D., & Stedmon, A. W. (2012). Negotiating left-hand and right-hand bends: a motorcycle simulator study to investigate experiential and behaviour differences across rider groups. PLoS ONE, 7(1), Article e29978. https://doi.org/10.1371/journal.pone.0029978Why do motorcyclists crash on bends? To address this question we examined the riding styles of three groups of
motorcyclists on a motorcycle simulator. Novice, experienced and advanced motorcyclists navigated a series of combined
left and right ben... Read More about Negotiating left-hand and right-hand bends: a motorcycle simulator study to investigate experiential and behaviour differences across rider groups.
Dopamine in nucleus accumbens: salience modulation in latent inhibition and overshadowing (2012)
Journal Article
Nelson, A. J., Thur, K. E., Marsden, C., & Cassaday, H. J. (2012). Dopamine in nucleus accumbens: salience modulation in latent inhibition and overshadowing. Journal of Psychopharmacology, 25(12), https://doi.org/10.1177/0269881110389211Latent inhibition (LI) is demonstrated when non-reinforced pre-exposure to a to-be-conditioned stimulus retards later learning. Learning is similarly retarded in overshadowing, in this case using the relative intensity of competing cues to manipulate... Read More about Dopamine in nucleus accumbens: salience modulation in latent inhibition and overshadowing.
On the control of secondary carbanion structure utilising ligand effects during directed metallation (2012)
Journal Article
Wheatley, A. E., Clayden, J., Hillier, I. H., Campbell Smith, A., Vincent, M. A., Taylor, L. J., & Haywood, J. (2012). On the control of secondary carbanion structure utilising ligand effects during directed metallation. Beilstein Journal of Organic Chemistry, 8, 50-60. https://doi.org/10.3762/bjoc.8.5N,N-Diisopropyl-2-propylbenzamide 6-H undergoes lateral deprotonation by t-BuLi in the presence of the Lewis base PMDTA (N,N,N′,N″,N″-pentamethyldiethylenetriamine) to give a benzyllithium 6-Lil·PMDTA that incorporates a trigonal planar secondary car... Read More about On the control of secondary carbanion structure utilising ligand effects during directed metallation.
Improved measurements of the intergalactic medium temperature around quasars: possible evidence for the initial stages of He-II reionisation at z~6 (2012)
Journal Article
S. Bolton, J., D. Becker, G., Raskutti, S., Stuart B. Wyithe, J., G. Haehnelt, M., & L. W. Sargent, W. (2012). Improved measurements of the intergalactic medium temperature around quasars: possible evidence for the initial stages of He-II reionisation at z~6. Monthly Notices of the Royal Astronomical Society, 419(4), 2880–2892. https://doi.org/10.1111/j.1365-2966.2011.19929.xWe present measurements of the intergalactic medium (IGM) temperature within ~5 proper Mpc of seven luminous quasars at z~6. The constraints are obtained from the Doppler widths of Lyman-alpha absorption lines in the quasar near-zones and build upon... Read More about Improved measurements of the intergalactic medium temperature around quasars: possible evidence for the initial stages of He-II reionisation at z~6.
Focus on underperformance, and how to address this (2012)
Journal Article
Cleland, J., & Patel, R. (2012). Focus on underperformance, and how to address this. Clinical Teacher, 9(1), 65-66. https://doi.org/10.1111/j.1743-498x.2011.00522.x
The Role of Humoral Innate Immunity in Hepatitis C Virus Infection (2012)
Journal Article
Tarr, A. W., Urbanowicz, R. A., & Ball, J. K. (2012). The Role of Humoral Innate Immunity in Hepatitis C Virus Infection. Viruses, 4(1), 1-27. https://doi.org/10.3390/v4010001Infection with Hepatitis C Virus (HCV) causes chronic disease in approximately 80% of cases, resulting in chronic inflammation and cirrhosis. Current treatments are not completely effective, and a vaccine has yet to be developed. Spontaneous resoluti... Read More about The Role of Humoral Innate Immunity in Hepatitis C Virus Infection.
Folate transporter expression decreases in the human placenta throughout pregnancy and in pre-eclampsia (2012)
Journal Article
Williams, P. J., Mistry, H. D., & Morgan, L. (2012). Folate transporter expression decreases in the human placenta throughout pregnancy and in pre-eclampsia. Pregnancy Hypertension, 2(2), https://doi.org/10.1016/j.preghy.2011.12.001The transport of folate across the placenta involves a number of different receptors including folate receptor-alpha (FR-α), reduced folate carrier (RFC) and proton coupled folate transporter (PCFT). In addition there are a number of ATP-dependent tr... Read More about Folate transporter expression decreases in the human placenta throughout pregnancy and in pre-eclampsia.
Spin-lattice relaxation rates and water content of freeze-dried articular cartilage (2012)
Journal Article
Damion, R. A., Pawaskar, S. S., Ries, M. E., Ingham, E., Williams, S., Jin, Z., & Radjenovic, A. (2012). Spin-lattice relaxation rates and water content of freeze-dried articular cartilage. Osteoarthritis and Cartilage, 20(2), 184-190. https://doi.org/10.1016/j.joca.2011.12.005Objective: Nuclear magnetic resonance (NMR) spin-lattice relaxation rates were measured in bovine and porcine articular cartilage as a function of water content. Methods: Water content was varied by freeze-drying samples for short periods of time (up... Read More about Spin-lattice relaxation rates and water content of freeze-dried articular cartilage.
Moderate multiple parentage and low genetic variation reduces the potential for genetic incompatibility avoidance despite high risk of inbreeding (2012)
Journal Article
Tuni, C., Goodacre, S., Bechsgaard, J., & Bilde, T. (2012). Moderate multiple parentage and low genetic variation reduces the potential for genetic incompatibility avoidance despite high risk of inbreeding. PLoS ONE, 7(1), Article e29636. https://doi.org/10.1371/journal.pone.0029636Background
Polyandry is widespread throughout the animal kingdom. In the absence of direct benefits of mating with different males, the underlying basis for polyandry is enigmatic because it can carry considerable costs such as elevated exposure t... Read More about Moderate multiple parentage and low genetic variation reduces the potential for genetic incompatibility avoidance despite high risk of inbreeding.