All Outputs (670)

‘Appropriate’ medical treatment: what’s in a word? (2012)
Journal Article
Phull, J., & Bartlett, P. (2012). ‘Appropriate’ medical treatment: what’s in a word?. Medicine, Science and the Law, https://doi.org/10.1258/msl.2011.011023

Following the amendments in the 2007 Act, there were several revisions made focusing largely on community treatment orders and deprivation of liberty of persons lacking capacity. One of the amendments included a requirement that ‘appropriate treatmen... Read More about ‘Appropriate’ medical treatment: what’s in a word?.

Integration of DNA into bacterial chromosomes from plasmids without a counter-selection marker (2012)
Journal Article
Heap, J. T., Ehsaan, M., Cooksley, C. M., Ng, Y., Cartman, S. T., Winzer, K., & Minton, N. P. (2012). Integration of DNA into bacterial chromosomes from plasmids without a counter-selection marker. Nucleic Acids Research, 40(8), Article 10. https://doi.org/10.1093/nar/gkr1321

Most bacteria can only be transformed with circular plasmids, so robust DNA integration methods for these rely upon selection of single-crossover clones followed by counter-selection of double-crossover clones. To overcome the limited availability of... Read More about Integration of DNA into bacterial chromosomes from plasmids without a counter-selection marker.

Fluoxetine counteracts the cognitive and cellular effects of 5-Fluorouracil in the rat hippocampus by a mechanism of prevention rather than recovery (2012)
Journal Article
Lyons, L., ELBeltagy, M., Bennett, G., & Wigmore, P. (2012). Fluoxetine counteracts the cognitive and cellular effects of 5-Fluorouracil in the rat hippocampus by a mechanism of prevention rather than recovery. PLoS ONE, 7(1), Article e30010. https://doi.org/10.1371/journal.pone.0030010

5-Fluorouracil (5-FU) is a cytostatic drug associated with chemotherapy-induced cognitive impairments that many cancer patients experience after treatment. Previous work in rodents has shown that 5-FU reduces hippocampal cell proliferation, a possi... Read More about Fluoxetine counteracts the cognitive and cellular effects of 5-Fluorouracil in the rat hippocampus by a mechanism of prevention rather than recovery.

Hans Christoph Buch’s Sansibar Blues and the fascination of cross-cultural experience in contemporary German historical novels about colonialism (2012)
Journal Article
Göttsche, D. (2012). Hans Christoph Buch’s Sansibar Blues and the fascination of cross-cultural experience in contemporary German historical novels about colonialism. German Life and Letters, 65(1), https://doi.org/10.1111/j.1468-0483.2011.01563.x

This article maps four different types of cross-cultural experience in contemporary historical novels about colonial Africa (colonialist, exoticist, intercultural, and transcultural) before focusing on Buch’s Sansibar Blues (2008) as a case study in... Read More about Hans Christoph Buch’s Sansibar Blues and the fascination of cross-cultural experience in contemporary German historical novels about colonialism.

Simple Near Exact Image Solution for Vertical Antenna Above Lossy Ground Using Stationary Phase Approximation (2012)
Presentation / Conference Contribution
Tahanian, E., Dadashzadeh, G., & Taghvaee, H. Simple Near Exact Image Solution for Vertical Antenna Above Lossy Ground Using Stationary Phase Approximation. Presented at IEEE NEMO 2012 (Numerical Electromagnetic Modeling and Optimization)

In this paper, the traditional problem of field computation for a vertical radiating antenna above a lossy infinite ground is discussed and revisited. To simplify and solve the traditional solutions consist of complicated integrals of sommerfeld type... Read More about Simple Near Exact Image Solution for Vertical Antenna Above Lossy Ground Using Stationary Phase Approximation.

Ball and rackets: inferring fiber fanning from diffusion-weighted MRI (2012)
Journal Article
Sotiropoulos, S. N., Behrens, T. E., & Jbabdi, S. (2012). Ball and rackets: inferring fiber fanning from diffusion-weighted MRI. NeuroImage, 60(2), https://doi.org/10.1016/j.neuroimage.2012.01.056

A number of methods have been proposed for resolving crossing fibers from diffusion-weighted (DW) MRI. However, other complex fiber geometries have drawn minimal attention. In this study, we focus on fiber orientation dispersion induced by within-vox... Read More about Ball and rackets: inferring fiber fanning from diffusion-weighted MRI.

Exposure to bisphosphonates and risk of cancer: a protocol for nested caseecontrol studies using the QResearch primary care database (2012)
Journal Article
Vinogradova, Y., Coupland, C., & Hippisley-Cox, J. (2012). Exposure to bisphosphonates and risk of cancer: a protocol for nested caseecontrol studies using the QResearch primary care database. BMJ Open, 2(1), Article e000548. https://doi.org/10.1136/bmjopen-2011-000548

Introduction: Bisphosphonates are becoming a common treatment for osteoporosis particularly after discovery of the association between hormone replacement therapy and increased risk of breast cancer. As osteoporosis develops with age, treatment... Read More about Exposure to bisphosphonates and risk of cancer: a protocol for nested caseecontrol studies using the QResearch primary care database.

Hemispheric dispersion of radioactive plume laced with fission nuclides from the Fukushima nuclear event (2012)
Journal Article
Hsu, S., Huh, C., Chan, C., Lin, S., Lin, F., & Liu, S. C. (2012). Hemispheric dispersion of radioactive plume laced with fission nuclides from the Fukushima nuclear event. Geophysical Research Letters, 39(7), https://doi.org/10.1029/2011GL049986

Radioactivities of particulate 131I and 137Cs released from the Fukushima nuclear accident were monitored in a regional aerosol network including two high mountain sites (central Taiwan and Tibetan Plateau). The results were integrated with data meas... Read More about Hemispheric dispersion of radioactive plume laced with fission nuclides from the Fukushima nuclear event.

Quantization of the massive gravitino on FRW spacetimes (2012)
Journal Article
Schenkel, A., & F. Uhlemann, C. (2012). Quantization of the massive gravitino on FRW spacetimes. Physical Review D - Particles, Fields, Gravitation and Cosmology, 85(2), Article 024011. https://doi.org/10.1103/PhysRevD.85.024011

In this article we study the quantization and causal properties of a massive spin 3/2 Rarita-Schwinger field on spatially flat Friedmann-Robertson-Walker (FRW) spacetimes. We construct Zuckerman's universal conserved current and prove that it leads t... Read More about Quantization of the massive gravitino on FRW spacetimes.

Negotiating left-hand and right-hand bends: a motorcycle simulator study to investigate experiential and behaviour differences across rider groups (2012)
Journal Article
Crundall, E., Crundall, D., & Stedmon, A. W. (2012). Negotiating left-hand and right-hand bends: a motorcycle simulator study to investigate experiential and behaviour differences across rider groups. PLoS ONE, 7(1), Article e29978. https://doi.org/10.1371/journal.pone.0029978

Why do motorcyclists crash on bends? To address this question we examined the riding styles of three groups of motorcyclists on a motorcycle simulator. Novice, experienced and advanced motorcyclists navigated a series of combined left and right ben... Read More about Negotiating left-hand and right-hand bends: a motorcycle simulator study to investigate experiential and behaviour differences across rider groups.

Dopamine in nucleus accumbens: salience modulation in latent inhibition and overshadowing (2012)
Journal Article
Nelson, A. J., Thur, K. E., Marsden, C., & Cassaday, H. J. (2012). Dopamine in nucleus accumbens: salience modulation in latent inhibition and overshadowing. Journal of Psychopharmacology, 25(12), https://doi.org/10.1177/0269881110389211

Latent inhibition (LI) is demonstrated when non-reinforced pre-exposure to a to-be-conditioned stimulus retards later learning. Learning is similarly retarded in overshadowing, in this case using the relative intensity of competing cues to manipulate... Read More about Dopamine in nucleus accumbens: salience modulation in latent inhibition and overshadowing.

On the control of secondary carbanion structure utilising ligand effects during directed metallation (2012)
Journal Article
Wheatley, A. E., Clayden, J., Hillier, I. H., Campbell Smith, A., Vincent, M. A., Taylor, L. J., & Haywood, J. (2012). On the control of secondary carbanion structure utilising ligand effects during directed metallation. Beilstein Journal of Organic Chemistry, 8, 50-60. https://doi.org/10.3762/bjoc.8.5

N,N-Diisopropyl-2-propylbenzamide 6-H undergoes lateral deprotonation by t-BuLi in the presence of the Lewis base PMDTA (N,N,N′,N″,N″-pentamethyldiethylenetriamine) to give a benzyllithium 6-Lil·PMDTA that incorporates a trigonal planar secondary car... Read More about On the control of secondary carbanion structure utilising ligand effects during directed metallation.

Improved measurements of the intergalactic medium temperature around quasars: possible evidence for the initial stages of He-II reionisation at z~6 (2012)
Journal Article
S. Bolton, J., D. Becker, G., Raskutti, S., Stuart B. Wyithe, J., G. Haehnelt, M., & L. W. Sargent, W. (2012). Improved measurements of the intergalactic medium temperature around quasars: possible evidence for the initial stages of He-II reionisation at z~6. Monthly Notices of the Royal Astronomical Society, 419(4), 2880–2892. https://doi.org/10.1111/j.1365-2966.2011.19929.x

We present measurements of the intergalactic medium (IGM) temperature within ~5 proper Mpc of seven luminous quasars at z~6. The constraints are obtained from the Doppler widths of Lyman-alpha absorption lines in the quasar near-zones and build upon... Read More about Improved measurements of the intergalactic medium temperature around quasars: possible evidence for the initial stages of He-II reionisation at z~6.

Focus on underperformance, and how to address this (2012)
Journal Article
Cleland, J., & Patel, R. (2012). Focus on underperformance, and how to address this. Clinical Teacher, 9(1), 65-66. https://doi.org/10.1111/j.1743-498x.2011.00522.x

The Role of Humoral Innate Immunity in Hepatitis C Virus Infection (2012)
Journal Article
Tarr, A. W., Urbanowicz, R. A., & Ball, J. K. (2012). The Role of Humoral Innate Immunity in Hepatitis C Virus Infection. Viruses, 4(1), 1-27. https://doi.org/10.3390/v4010001

Infection with Hepatitis C Virus (HCV) causes chronic disease in approximately 80% of cases, resulting in chronic inflammation and cirrhosis. Current treatments are not completely effective, and a vaccine has yet to be developed. Spontaneous resoluti... Read More about The Role of Humoral Innate Immunity in Hepatitis C Virus Infection.

Folate transporter expression decreases in the human placenta throughout pregnancy and in pre-eclampsia (2012)
Journal Article
Williams, P. J., Mistry, H. D., & Morgan, L. (2012). Folate transporter expression decreases in the human placenta throughout pregnancy and in pre-eclampsia. Pregnancy Hypertension, 2(2), https://doi.org/10.1016/j.preghy.2011.12.001

The transport of folate across the placenta involves a number of different receptors including folate receptor-alpha (FR-α), reduced folate carrier (RFC) and proton coupled folate transporter (PCFT). In addition there are a number of ATP-dependent tr... Read More about Folate transporter expression decreases in the human placenta throughout pregnancy and in pre-eclampsia.

Spin-lattice relaxation rates and water content of freeze-dried articular cartilage (2012)
Journal Article
Damion, R. A., Pawaskar, S. S., Ries, M. E., Ingham, E., Williams, S., Jin, Z., & Radjenovic, A. (2012). Spin-lattice relaxation rates and water content of freeze-dried articular cartilage. Osteoarthritis and Cartilage, 20(2), 184-190. https://doi.org/10.1016/j.joca.2011.12.005

Objective: Nuclear magnetic resonance (NMR) spin-lattice relaxation rates were measured in bovine and porcine articular cartilage as a function of water content. Methods: Water content was varied by freeze-drying samples for short periods of time (up... Read More about Spin-lattice relaxation rates and water content of freeze-dried articular cartilage.

Moderate multiple parentage and low genetic variation reduces the potential for genetic incompatibility avoidance despite high risk of inbreeding (2012)
Journal Article
Tuni, C., Goodacre, S., Bechsgaard, J., & Bilde, T. (2012). Moderate multiple parentage and low genetic variation reduces the potential for genetic incompatibility avoidance despite high risk of inbreeding. PLoS ONE, 7(1), Article e29636. https://doi.org/10.1371/journal.pone.0029636

Background Polyandry is widespread throughout the animal kingdom. In the absence of direct benefits of mating with different males, the underlying basis for polyandry is enigmatic because it can carry considerable costs such as elevated exposure t... Read More about Moderate multiple parentage and low genetic variation reduces the potential for genetic incompatibility avoidance despite high risk of inbreeding.

Compliance with mandatory reporting of clinical trial results on ClinicalTrials.gov: cross sectional study (2012)
Journal Article
Prayle, A., Hurley, M., & Smyth, A. R. (2012). Compliance with mandatory reporting of clinical trial results on ClinicalTrials.gov: cross sectional study. BMJ, 2011(344), Article d7373. https://doi.org/10.1136/bmj.d7373

Objective To examine compliance with mandatory reporting of summary clinical trial results (within one year of completion of trial) on ClinicalTrials.gov for studies that fall under the recent Food and Drug Administration Amendments Act (FDAAA) legis... Read More about Compliance with mandatory reporting of clinical trial results on ClinicalTrials.gov: cross sectional study.

Biosecurity on cattle farms: a study in North-West England (2012)
Journal Article
Brennan, M. L., & Christley, R. M. (2012). Biosecurity on cattle farms: a study in North-West England. PLoS ONE, 7(1), Article e28139. https://doi.org/10.1371/journal.pone.0028139

Background: Few studies have considered in detail the range of biosecurity practices undertaken on cattle farms, particularly within the UK. In this study, 56 cattle farmers in a 100 km2 area of north-west England were questioned regarding their on-f... Read More about Biosecurity on cattle farms: a study in North-West England.