All Outputs (482)

The effect of catecholaminergic depletion within the prelimbic and infralimbic medial prefrontal cortex on recognition memory for recency, location, and objects (2011)
Journal Article
Nelson, A. J., Cooper, M. T., Thur, K. E., Marsden, C. A., & Cassaday, H. J. (2011). The effect of catecholaminergic depletion within the prelimbic and infralimbic medial prefrontal cortex on recognition memory for recency, location, and objects. Behavioral Neuroscience, 125(3), https://doi.org/10.1037/a0023337

There is good evidence that the medial prefrontal cortex (mPFC) is involved in different aspects of recognition memory. However, the mPFC is a heterogeneous structure, and the contribution of the prelimbic (PL) and infralimbic (IL) cortices to recogn... Read More about The effect of catecholaminergic depletion within the prelimbic and infralimbic medial prefrontal cortex on recognition memory for recency, location, and objects.

Overtime and psychological well-being among Chinese office workers (2011)
Journal Article
Houdmont, J., Zhou, J., & Hassard, J. (2011). Overtime and psychological well-being among Chinese office workers. Occupational Medicine, 61(4), https://doi.org/10.1093/occmed/kqr029

Background: Research on the relationship between overtime and psychological well-being, and workers’ perceptions of the factors that determine overtime, has been conducted exclusively in the Western cultural context. Aims: To examine whether existin... Read More about Overtime and psychological well-being among Chinese office workers.

Possible roles for folic acid in the regulation of trophoblast invasion and placental development in normal early human pregnancy (2011)
Journal Article
Williams, P. J., Bulmer, J. N., Innes, B. A., & Broughton Pipkin, F. (2011). Possible roles for folic acid in the regulation of trophoblast invasion and placental development in normal early human pregnancy. Biology of Reproduction, 84(6), https://doi.org/10.1095/biolreprod.110.088351

In addition to its role in the prevention of neural tube defects, folic acid has many other physiological functions, including cell proliferation, DNA replication, and antioxidant protection. The aim of this study was to determine the role that folic... Read More about Possible roles for folic acid in the regulation of trophoblast invasion and placental development in normal early human pregnancy.

An Opportunity Lost? Exploring the benefits of the Child Trust Fund on youth transitions into adulthood (2011)
Journal Article
Gregory, L. (2011). An Opportunity Lost? Exploring the benefits of the Child Trust Fund on youth transitions into adulthood. Youth and Policy, 106, 78-94

With the decision to abolish the Child Trust Fund announced by the Conservative/Liberal Democrat Coalition in May 2010, this paper explores what impact the abandonment of a unique policy innovation will have in relation to youth transitions: in so do... Read More about An Opportunity Lost? Exploring the benefits of the Child Trust Fund on youth transitions into adulthood.

Geographies of money and finance II: Financialization and financial subjects (2011)
Journal Article
Hall, S. (2012). Geographies of money and finance II: Financialization and financial subjects. Progress in Human Geography, 36(3), 403-411. https://doi.org/10.1177/0309132511403889

In this report, I examine the growing interest in financial subjects within economic geography and the wider social sciences. I begin by locating this literature within work on financialization and earlier geographical research on money and finance.... Read More about Geographies of money and finance II: Financialization and financial subjects.

The special systems biology of the sperm (2011)
Journal Article
Anand-Ivell, R., & Ivell, R. (2011). The special systems biology of the sperm. Biochemical Journal, 436(3), e3-e5. https://doi.org/10.1042/BJ20110766

Spermatozoa represent a highly specialized cell type, with a minimalist structure designed to fulfil a single principal function: the transport of an intact single-copy haploid genome to the site of fertilization in the oviduct, and consequent zygote... Read More about The special systems biology of the sperm.

The role of oxidative stress and antioxidant supplementation in pregnancy disorders (2011)
Journal Article
Poston, L., Igosheva, N., Mistry, H. D., Seed, P. T., Shennan, A. H., Rana, S., …Chappell, L. C. (2011). The role of oxidative stress and antioxidant supplementation in pregnancy disorders. American Journal of Clinical Nutrition, 94(6Suppl), Article 1980S-1985S. https://doi.org/10.3945/ajcn.110.001156

Oxidative stress is widely implicated in failed reproductive performance including infertility, miscarriage, diabetes-related congenital malformations and preeclampsia. Maternal obesity is a strong risk factor for preeclampsia, and recently, in an an... Read More about The role of oxidative stress and antioxidant supplementation in pregnancy disorders.

Uniform cell colonization of porous 3-D scaffolds achieved using radial control of surface chemistry (2011)
Journal Article
Intranuovo, F., Howard, D., White, L. J., Johal, R. K., Ghaemmaghami, A. M., Favia, P., …Alexander, M. R. (2011). Uniform cell colonization of porous 3-D scaffolds achieved using radial control of surface chemistry. Acta Biomaterialia, 7(9), 3336-3344. https://doi.org/10.1016/j.actbio.2011.05.020

Uniform cellular distribution is a prerequisite to forming tissue within porous scaffolds, but the seeding process often results in preferential adhesion of cells at the periphery. We develop a vapour phase coating strategy which is readily applicabl... Read More about Uniform cell colonization of porous 3-D scaffolds achieved using radial control of surface chemistry.

An interpretative phenomenological analysis of posttraumatic growth in adults bereaved by suicide (2011)
Journal Article
Smith, A., Joseph, S., & das Nair, R. (in press). An interpretative phenomenological analysis of posttraumatic growth in adults bereaved by suicide. Journal of Loss and Trauma, 16(5), https://doi.org/10.1080/15325024.2011.572047

This study explored experiences of posttraumatic growth in adults bereaved by suicide. Six participants were interviewed using a semi-structured interview schedule. Transcribed interviews were analyzed from an interpretative phenomenological framewor... Read More about An interpretative phenomenological analysis of posttraumatic growth in adults bereaved by suicide.

The pragmatic face of the covert idealist: the role of Allen Dulles in US policy discussions on Latin America, 1953–61 (2011)
Journal Article
Sewell, B. (2011). The pragmatic face of the covert idealist: the role of Allen Dulles in US policy discussions on Latin America, 1953–61. Intelligence and National Security, 26(2-3), https://doi.org/10.1080/02684527.2011.559319

Assessments of the CIA’s role in Latin America during the 1950s have tended to focus predominantly on the twin case-studies of Guatemala and Cuba. Consequently, the Agency’s role – and, more broadly, that of its head Allen Dulles – has come to be see... Read More about The pragmatic face of the covert idealist: the role of Allen Dulles in US policy discussions on Latin America, 1953–61.

Facing the Future? David Owen and Social Democracy in the 1980s and Beyond (2011)
Journal Article
Blackburn, D. (2011). Facing the Future? David Owen and Social Democracy in the 1980s and Beyond. Parliamentary Affairs, 64(4), 634-651. https://doi.org/10.1093/pa/gsr015

David Owen entered the House of Commons as member for Plymouth in 1966. He became a junior minister under Harold Wilson by 1968 and quickly established himself as a leading figure of the Labour right. From 1977 to 1979 he was Britain's youngest post-... Read More about Facing the Future? David Owen and Social Democracy in the 1980s and Beyond.

Cyclophilin A interacts with domain II of hepatitis C virus NS5A and stimulates RNA binding in an isomerase-dependent manner (2011)
Journal Article
Foster, T. L., Gallay, P., Stonehouse, N. J., & Harris, M. (2011). Cyclophilin A interacts with domain II of hepatitis C virus NS5A and stimulates RNA binding in an isomerase-dependent manner. Journal of Virology, 85(14), 7460-7464. https://doi.org/10.1128/jvi.00393-11

NS5A plays a critical, yet poorly defined, role in hepatitis C virus genome replication. The protein consists of three domains, each of which is able to bind independently to the 3′ untranslated region (UTR) of the viral positive strand genomic RNA.... Read More about Cyclophilin A interacts with domain II of hepatitis C virus NS5A and stimulates RNA binding in an isomerase-dependent manner.

INSL3 in the ruminant: A powerful indicator of gender- and genetic-specific feto-maternal dialogue (2011)
Journal Article
Anand-Ivell, R., Hiendleder, S., Viñoles, C., Martin, G. B., Fitzsimmons, C., Eurich, A., …Ivell, R. (2011). INSL3 in the ruminant: A powerful indicator of gender- and genetic-specific feto-maternal dialogue. PLoS ONE, 6(5), 1-7. https://doi.org/10.1371/journal.pone.0019821

The hormone Insulin-like peptide 3 (INSL3) is a major secretory product of the Leydig cells from both fetal and adult testes. Consequently, it is a major gender-specific circulating hormone in the male fetus, where it is responsible for the first pha... Read More about INSL3 in the ruminant: A powerful indicator of gender- and genetic-specific feto-maternal dialogue.

Chapter 1 - The structure of the adenosine receptors implications for drug discovery (2011)
Journal Article
Lane, J. R., Jaakola, V., & Ijzerman, A. P. (2011). Chapter 1 - The structure of the adenosine receptors implications for drug discovery. Advances in Pharmacology, 61, 1-40. https://doi.org/10.1016/B978-0-12-385526-8.00001-1

Extracellular adenosine mediates most of its physiological effects via an interaction with four G protein-coupled receptors (GPCRs), the adenosine receptors (ARs). These ARs are important pharmacological targets in the treatment of a wide variety of... Read More about Chapter 1 - The structure of the adenosine receptors implications for drug discovery.

Going paperless at the emergency department: A socio-technical study of an information system for patient tracking (2011)
Journal Article
Vezyridis, P., Timmons, S., & Wharrad, H. (2011). Going paperless at the emergency department: A socio-technical study of an information system for patient tracking. International Journal of Medical Informatics, 80(7), 455-465. https://doi.org/10.1016/j.ijmedinf.2011.04.001

Purpose: The purpose of this study was to examine nurses' attitudes and reflection on the transformation of their workpractices after the implementation of an Emergency Department Information System (EDIS). Methods: A qualitative study using intervie... Read More about Going paperless at the emergency department: A socio-technical study of an information system for patient tracking.

Nonsmooth dynamics in spiking neuron models (2011)
Journal Article
Coombes, S., Thul, R., & Wedgwood, K. C. (2012). Nonsmooth dynamics in spiking neuron models. Physica D: Nonlinear Phenomena, 241(22), https://doi.org/10.1016/j.physd.2011.05.012

Large scale studies of spiking neural networks are a key part of modern approaches to understanding the dynamics of biological neural tissue. One approach in computational neuroscience has been to consider the detailed electrophysiological propertie... Read More about Nonsmooth dynamics in spiking neuron models.

H-NS mediates the dissociation of a refractory protein–DNA complex during Tn10/IS10 transposition (2011)
Journal Article
Liu, D., Haniford, D. B., & Chalmers, R. (2011). H-NS mediates the dissociation of a refractory protein–DNA complex during Tn10/IS10 transposition. Nucleic Acids Research, 39(15), https://doi.org/10.1093/nar/gkr309

Tn10/IS10 transposition takes place in the context of a protein–DNA complex called a transpososome. During the reaction, the transpososome undergoes several conformational changes. The host proteins IHF and H-NS, which also are global regulators of g... Read More about H-NS mediates the dissociation of a refractory protein–DNA complex during Tn10/IS10 transposition.

Visual motion induces a forward prediction of spatial pattern (2011)
Journal Article
Roach, N. W., McGraw, P. V., & Johnston, A. (2011). Visual motion induces a forward prediction of spatial pattern. Current Biology, 21(9), https://doi.org/10.1016/j.cub.2011.03.031

Cortical motion analysis continuously encodes image velocity but might also be used to predict future patterns of sensory input along the motion path. We asked whether this predictive aspect of motion is exploited by the human visual system. Targets... Read More about Visual motion induces a forward prediction of spatial pattern.

Motivating mobility: designing for lived motivation in stroke rehabilitation (2011)
Book Chapter
Balaam, M., Rennick Egglestone, S., Fitzpatrick, G., Rodden, T., Hughes, A., Wilkinson, A., …Burridge, J. (2011). Motivating mobility: designing for lived motivation in stroke rehabilitation. In D. Tan, B. Begole, & W. Kellog (Eds.), CHI 2011: conference proceedings and extended abstracts: 29th Annual Conference on Human Factors in Computing Systems, Vancouver, British Columbia, Canada, May 7-12, 2011. ACM Press. https://doi.org/10.1145/1978942.1979397

How to motivate and support behaviour change through design is becoming of increasing interest to the CHI community. In this paper, we present our experiences of building systems that motivate people to engage in upper limb rehabilitation exercise af... Read More about Motivating mobility: designing for lived motivation in stroke rehabilitation.

Effect of questionnaire length, personalisation and reminder type on response rate to a complex postal survey: Randomised controlled trial (2011)
Journal Article
Sahlqvist, S., Song, Y., Bull, F., Adams, E., Preston, J., & Ogilvie, D. (2011). Effect of questionnaire length, personalisation and reminder type on response rate to a complex postal survey: Randomised controlled trial. BMC Medical Research Methodology, 11(62), https://doi.org/10.1186/1471-2288-11-62

Background Minimising participant non-response in postal surveys helps to maximise the generalisability of the inferences made from the data collected. The aim of this study was to examine the effect of questionnaire length, personalisation and remi... Read More about Effect of questionnaire length, personalisation and reminder type on response rate to a complex postal survey: Randomised controlled trial.