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Resistance mutations define specific antiviral effects for inhibitors of the hepatitis C virus p7 ion channel (2011)
Journal Article
Foster, T. L., Verow, M., Wozniak, A. L., Bentham, M. J., Thompson, J., Atkins, E., …Griffin, S. (2011). Resistance mutations define specific antiviral effects for inhibitors of the hepatitis C virus p7 ion channel. Hepatology, 54(1), 79-90. https://doi.org/10.1002/hep.24371

The hepatitis C virus (HCV) p7 ion channel plays a critical role during infectious virus production and represents an important new therapeutic target. Its activity is blocked by structurally distinct classes of small molecules, with sensitivity vary... Read More about Resistance mutations define specific antiviral effects for inhibitors of the hepatitis C virus p7 ion channel.

Effects of orally administered Bdellovibrio bacteriovorus on the well-being and Salmonella colonization of young chicks (2011)
Journal Article
Atterbury, R. J., Hobley, L., Till, R., Lambert, C., Capeness, M. J., Lerner, T. R., …Sockett, R. E. (2011). Effects of orally administered Bdellovibrio bacteriovorus on the well-being and Salmonella colonization of young chicks. Applied and Environmental Microbiology, 77(16), https://doi.org/10.1128/AEM.00426-11

Bdellovibrio bacteriovorus is a bacterium which preys upon and kills Gram-negative bacteria, including the zoonotic pathogens Escherichia coli and Salmonella. Bdellovibrio has potential as a biocontrol agent, but no reports of it being tested in livi... Read More about Effects of orally administered Bdellovibrio bacteriovorus on the well-being and Salmonella colonization of young chicks.

Preventing childhood obesity during infancy in UK primary care: a mixed-methods study of HCPs' knowledge, beliefs and practice (2011)
Journal Article
Redsell, S. A., Atkinson, P. J., Nathan, D., Siriwardena, A. N., Swift, J. A., & Glazebrook, C. (2011). Preventing childhood obesity during infancy in UK primary care: a mixed-methods study of HCPs' knowledge, beliefs and practice. BMC Family Practice, 12(1), Article 54. https://doi.org/10.1186/1471-2296-12-54

Background There is a strong rationale for intervening in early childhood to prevent obesity. Over a quarter of infants gain weight more rapidly than desirable during the first six months of life putting them at greater risk of obesity in childhoo... Read More about Preventing childhood obesity during infancy in UK primary care: a mixed-methods study of HCPs' knowledge, beliefs and practice.

Breast cancer and age in Black and White women in South East England (2011)
Journal Article
Jack, R. H., Davies, E. A., & Møller, H. (2012). Breast cancer and age in Black and White women in South East England. International Journal of Cancer, 130(5), 1227-1229. https://doi.org/10.1002/ijc.26088

Black women have lower age-standardized breast cancer incidence rates than White women in the United Kingdom. However, little is known about such differences in risk in separate age groups. Records on female residents of South East England diagnosed... Read More about Breast cancer and age in Black and White women in South East England.

P-glycoprotein and breast cancer resistance protein in acute myeloid leukaemia cells treated with the Aurora-B Kinase Inhibitor barasertib-hQPA (2011)
Journal Article
Grundy, M., Seedhouse, C., Russell, N. H., & Pallis, M. (2011). P-glycoprotein and breast cancer resistance protein in acute myeloid leukaemia cells treated with the Aurora-B Kinase Inhibitor barasertib-hQPA. BMC Cancer, 11, Article 254. https://doi.org/10.1186/1471-2407-11-254

Background Aurora kinases play an essential role in orchestrating chromosome alignment, segregation and cytokinesis during mitotic progression, with both aurora-A and B frequently over-expressed in a variety of human malignancies. Over-expression of... Read More about P-glycoprotein and breast cancer resistance protein in acute myeloid leukaemia cells treated with the Aurora-B Kinase Inhibitor barasertib-hQPA.

China's charm offensive and peacekeeping: the lessons of Cambodia – what now for Sudan? (2011)
Journal Article
Hirono, M. (2011). China's charm offensive and peacekeeping: the lessons of Cambodia – what now for Sudan?. International Peacekeeping, 18(3), https://doi.org/10.1080/13533312.2011.563097

China's participation in UN peacekeeping is often viewed as a part of a global ‘charm offensive’ aimed at enhancing China's image in host countries. However, when viewed in the light of its support for dictatorial regimes in those host countries, do... Read More about China's charm offensive and peacekeeping: the lessons of Cambodia – what now for Sudan?.

Role of amygdala-prefrontal cortex circuitry in regulating the expression of contextual fear memory (2011)
Journal Article
Stevenson, C. W. (2011). Role of amygdala-prefrontal cortex circuitry in regulating the expression of contextual fear memory. Neurobiology of Learning and Memory, 96(2), 315-323. https://doi.org/10.1016/j.nlm.2011.06.005

The basolateral amygdala (BLA) and medial prefrontal cortex (mPFC) are inter-connected regions involved in fear memory expression. The reciprocal nature of projections between these areas differs along the rostrocaudal extent of BLA. This study inves... Read More about Role of amygdala-prefrontal cortex circuitry in regulating the expression of contextual fear memory.

An investigation of the failure mechanisms in high temperature materials subjected to isothermal and anisothermal fatigue and creep conditions (2011)
Journal Article
Hyde, C. J., Sun, W., & Hyde, T. (in press). An investigation of the failure mechanisms in high temperature materials subjected to isothermal and anisothermal fatigue and creep conditions. Procedia Engineering, 10, https://doi.org/10.1016/j.proeng.2011.04.192

Many engineering components are subjected to conditions which have a detrimental effect on the materials from which they are made. Such components are used, for example, within high temperature regions of aeroengines (e.g. turbine discs) and power pl... Read More about An investigation of the failure mechanisms in high temperature materials subjected to isothermal and anisothermal fatigue and creep conditions.

A review of recent developments in climate change science. Part II: The global-scale impacts of climate change (2011)
Journal Article
Gosling, S. N., Warren, R., Arnell, N. W., Good, P., Caesar, J., Bernie, D., …Smith, S. M. (2011). A review of recent developments in climate change science. Part II: The global-scale impacts of climate change. Progress in Physical Geography, 35(4), 443-464. https://doi.org/10.1177/0309133311407650

This article presents a review of recent developments in studies assessing the global-scale impacts of climate change published since the Intergovernmental Panel on Climate Change (IPCC) Fourth Assessment Report (AR4). Literature covering six main im... Read More about A review of recent developments in climate change science. Part II: The global-scale impacts of climate change.

Expression of thioredoxin system and related peroxiredoxin proteins is associated with clinical outcome in radiotherapy treated early stage breast cancer (2011)
Journal Article
Woolston, C. M., Storr, S. J., Ellis, I. O., Morgan, D. A., & Martin, S. G. (2011). Expression of thioredoxin system and related peroxiredoxin proteins is associated with clinical outcome in radiotherapy treated early stage breast cancer. Radiotherapy and Oncology, 100(2), 308-313. https://doi.org/10.1016/j.radonc.2011.05.029

Background and purpose Deregulated redox systems provide cancer cells protection from increased oxidative stress, such as that induced by ionizing radiation. Expression of the thioredoxin system proteins (thioredoxin, thioredoxin reductase and thior... Read More about Expression of thioredoxin system and related peroxiredoxin proteins is associated with clinical outcome in radiotherapy treated early stage breast cancer.

A review of recent developments in climate change science. Part I: Understanding of future change in the large-scale climate system (2011)
Journal Article
Good, P., Caesar, J., Bernie, D., Lowe, J. A., van der Linden, P., Gosling, S. N., …McNeall, D. (2011). A review of recent developments in climate change science. Part I: Understanding of future change in the large-scale climate system. Progress in Physical Geography, 35(3), 281-296. https://doi.org/10.1177/0309133311407651

This article reviews some of the major lines of recent scientific progress relevant to the choice of global climate policy targets, focusing on changes in understanding since publication of the Intergovernmental Panel on Climate Change Fourth Assessm... Read More about A review of recent developments in climate change science. Part I: Understanding of future change in the large-scale climate system.

Use of the Affymetrix human GeneChip array and genomic DNA hybridisation probe selection to study ovine transcriptomes (2011)
Journal Article
Graham, N. S., May, S. T., Daniel, Z. C., Emmerson, Z. F., Brameld, J. M., & Parr, T. (2011). Use of the Affymetrix human GeneChip array and genomic DNA hybridisation probe selection to study ovine transcriptomes. Animal, 5(6), 861-866. https://doi.org/10.1017/S1751731110002533

Affymetrix GeneChip microarrays are a powerful tool to study global gene expression profiles and have been used on many species. However, no sheep-specific Affymetrix GeneChip is currently available and the bovine array is fairly limited in its cover... Read More about Use of the Affymetrix human GeneChip array and genomic DNA hybridisation probe selection to study ovine transcriptomes.

Trans-local academic credentials and the (re)production of financial elites (2011)
Journal Article
Hall, S., & Appleyard, L. (2011). Trans-local academic credentials and the (re)production of financial elites. Globalisation, Societies and Education, 9(2), 247-264. https://doi.org/10.1080/14767724.2011.577177

This paper examines the ways in which credentials from a range of education providers are used to (re)produce transnational financial elites in London's international financial district. Extant research has examined the long-standing relationship bet... Read More about Trans-local academic credentials and the (re)production of financial elites.

The impact of spatial fluctuations in the ultra-violet background on intergalactic carbon and silicon (2011)
Journal Article
S. Bolton, J., & Viel, M. (2011). The impact of spatial fluctuations in the ultra-violet background on intergalactic carbon and silicon. Monthly Notices of the Royal Astronomical Society, 414(1), 241–252. https://doi.org/10.1111/j.1365-2966.2011.18384.x

Spatial inhomogeneities in the spectral shape of the ultra-violet background (UVB) at the tail-end of HeII reionisation are thought to be the primary cause of the large fluctuations observed in the HeII to HI Ly-a forest optical depth ratio, tau_HeII... Read More about The impact of spatial fluctuations in the ultra-violet background on intergalactic carbon and silicon.

Multiscale analysis of pattern formation via intercellular signalling (2011)
Journal Article
O'Dea, R. D., & King, J. R. (2011). Multiscale analysis of pattern formation via intercellular signalling. Mathematical Biosciences, 231(2), https://doi.org/10.1016/j.mbs.2011.03.003

Lateral inhibition, a juxtacrine signalling mechanism by which a cell adopting a particular fate inhibits neighbouring cells from doing likewise, has been shown to be a robust mechanism for the formation of fine-grained spatial patterns (in which adj... Read More about Multiscale analysis of pattern formation via intercellular signalling.

Catecholaminergic depletion in nucleus accumbens enhances trace conditioning (2011)
Journal Article
Nelson, A. J., Thur, K. E., Spicer, C., Marsden, C., & Cassaday, H. J. (2011). Catecholaminergic depletion in nucleus accumbens enhances trace conditioning. Advances in Medical Sciences, 56(1), https://doi.org/10.2478/v10039-011-0014-2

Purpose: To examine the effect of dopamine depletion in nucleus accumbens on trace conditioning; to distinguish the role of core and shell sub-regions, as far as possible. Material/Methods: 6-hydroxydopamine was used to lesion dopamine terminals with... Read More about Catecholaminergic depletion in nucleus accumbens enhances trace conditioning.

The effect of catecholaminergic depletion within the prelimbic and infralimbic medial prefrontal cortex on recognition memory for recency, location, and objects (2011)
Journal Article
Nelson, A. J., Cooper, M. T., Thur, K. E., Marsden, C. A., & Cassaday, H. J. (2011). The effect of catecholaminergic depletion within the prelimbic and infralimbic medial prefrontal cortex on recognition memory for recency, location, and objects. Behavioral Neuroscience, 125(3), https://doi.org/10.1037/a0023337

There is good evidence that the medial prefrontal cortex (mPFC) is involved in different aspects of recognition memory. However, the mPFC is a heterogeneous structure, and the contribution of the prelimbic (PL) and infralimbic (IL) cortices to recogn... Read More about The effect of catecholaminergic depletion within the prelimbic and infralimbic medial prefrontal cortex on recognition memory for recency, location, and objects.