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All Outputs (365)

Analysis of the cone penetration test in layered clay (2010)
Journal Article
Walker, J., & Yu, H.-S. (2010). Analysis of the cone penetration test in layered clay. Géotechnique, 60(12), https://doi.org/10.1680/geot.7.00153

This paper presents an analysis of the cone penetration test in multi-layered clays using the commercial finite-element code Abaqus/Explicit. The von Mises yield criterion and its associated flow rule are assumed to model the plastic behaviour of ela... Read More about Analysis of the cone penetration test in layered clay.

A systems biology viewpoint on autophagy in health and disease (2010)
Journal Article
Huett, A., Goel, G., & Xavier, R. J. (2010). A systems biology viewpoint on autophagy in health and disease. Current Opinion in Gastroenterology, 26(4), 302-309. https://doi.org/10.1097/MOG.0b013e32833ae2ed

Purpose of review: The field of autophagy is rapidly expanding to encompass many important areas of cell biology, physiology and disease. Recent discoveries and tools allow the connection of the autophagy pathway to other cellular signals and process... Read More about A systems biology viewpoint on autophagy in health and disease.

Specific interaction of hepatitis C virus glycoproteins with mannan binding lectin inhibits virus entry (2010)
Journal Article
Brown, K. S., Keogh, M. J., Owsianka, A. M., Adair, R., Patel, A. H., Arnold, J. N., …Hickling, T. P. (2010). Specific interaction of hepatitis C virus glycoproteins with mannan binding lectin inhibits virus entry. Protein and Cell, 1(7), 664-674. https://doi.org/10.1007/s13238-010-0088-9

Mannan-binding lectin (MBL) is a soluble innate immune protein that binds to glycosylated targets. MBL acts as an opsonin and activates complement, contributing to the destruction and clearance of infecting microorganisms. Hepatitis C virus (HCV) enc... Read More about Specific interaction of hepatitis C virus glycoproteins with mannan binding lectin inhibits virus entry.

Towards the design of heuristics by means of self-assembly (2010)
Presentation / Conference Contribution
Terrazas, G., Landa-Silva, D., & Krasnogor, N. (2010). Towards the design of heuristics by means of self-assembly.

The current investigations on hyper-heuristics design have sprung up in two different flavours: heuristics that choose heuristics and heuristics that generate heuristics. In the latter, the goal is to develop a problem-domain independent strategy to... Read More about Towards the design of heuristics by means of self-assembly.

Determinants of physical activity participation following traumatic brain injury (2010)
Journal Article
Reavenall, S., & Blake, H. (2010). Determinants of physical activity participation following traumatic brain injury. International Journal of Therapy and Rehabilitation, 17(7), https://doi.org/10.12968/ijtr.2010.17.7.48893

Aims

The objective of the study described in this article was to establish the environmental, social, or personal determinants associated with physical activity participation in people with traumatic brain injury (TBI).
Methods

A multi-centre... Read More about Determinants of physical activity participation following traumatic brain injury.

Ensuring open access to European, Latin American and Caribbean research: a description of the OpenAIRE and NECOBELAC FP7 Projects (2010)
Journal Article
Furnival, C. (2010). Ensuring open access to European, Latin American and Caribbean research: a description of the OpenAIRE and NECOBELAC FP7 Projects. Aliss Quarterly, 5(4),

Brief article that outlines two Open Access projects, OpenAIRE – Open Access Infrastructure for Research in Europe – and NECOBELAC – Network of Collaboration between Europe and Latin American Caribbean Countries, both of which count on the input and... Read More about Ensuring open access to European, Latin American and Caribbean research: a description of the OpenAIRE and NECOBELAC FP7 Projects.

Effect of delivery method on the efficacy of Salmonella vaccination in chickens (2010)
Journal Article
Atterbury, R. J., Morris, V., Harrison, D., Tucker, V., Allen, V., Davies, R., & Carrique-Mas, J. (2010). Effect of delivery method on the efficacy of Salmonella vaccination in chickens. Veterinary Record, 167(5), https://doi.org/10.1136/vr.b4884

To investigate whether the efficacy of live vaccines is influenced by the mode of vaccine delivery, a widely-used UK live commercial Salmonella Enteritidis vaccine was delivered to pullet chicks either by spray, in drinking water, or in combination w... Read More about Effect of delivery method on the efficacy of Salmonella vaccination in chickens.

Large deformations in oriented polymer glasses: experimental study and a new glass-melt constitutive model (2010)
Journal Article
De Focatiis, D. S., Embery, J., & Buckley, C. (2010). Large deformations in oriented polymer glasses: experimental study and a new glass-melt constitutive model. Journal of Polymer Science Part B: Polymer Physics, 48(13), https://doi.org/10.1002/polb.22028

An experimental study was made of the effects of prior molecular orientation on large tensile deformations of polystyrene in the glassy state. A new hybrid glass-melt constitutive model is proposed for describing and understanding the results, achiev... Read More about Large deformations in oriented polymer glasses: experimental study and a new glass-melt constitutive model.

Outcomes after internal versus external tocodynamometry for monitoring labor (2010)
Journal Article
Bakker, J. J. . H., Verhoeven, C. J. . M., Janssen, P. F., van Lith, J. M., van Oudgaarden, E. D., Bloemenkamp, K. W. . M., …van der Post, J. A. . M. (2010). Outcomes after internal versus external tocodynamometry for monitoring labor. Obstetrical and Gynecological Survey, 65(6), 355-356. https://doi.org/10.1097/OGX.0b013e3181e59d45

Professional societies in obstetrics and gynecology have recommended the use of internal tocodynamometry to monitor uterine contractions during induction or augmentation of labor. This recommendation is based on the hypothesis that internal tocodynam... Read More about Outcomes after internal versus external tocodynamometry for monitoring labor.

All three domains of the Hepatitis C virus nonstructural NS5A protein contribute to RNA binding (2010)
Journal Article
Foster, T. L., Belyaeva, T., Stonehouse, N. J., Pearson, A. R., & Harris, M. (2010). All three domains of the Hepatitis C virus nonstructural NS5A protein contribute to RNA binding. Journal of Virology, 84(18), 9267-9277. https://doi.org/10.1128/jvi.00616-10

The hepatitis C virus (HCV) nonstructural protein NS5A is critical for viral genome replication and is thought to interact directly with both the RNA-dependent RNA polymerase, NS5B, and viral RNA. NS5A consists of three domains which have, as yet, un... Read More about All three domains of the Hepatitis C virus nonstructural NS5A protein contribute to RNA binding.

Characterization of [3H]LUF5834: A novel non-ribose high-affinity agonist radioligand for the adenosine A1 receptor (2010)
Journal Article
Lane, J. R., Klaasse, E., Lin, J., van Bruchem, J., Beukers, M. W., & Ijzerman, A. P. (2010). Characterization of [3H]LUF5834: A novel non-ribose high-affinity agonist radioligand for the adenosine A1 receptor. Biochemical Pharmacology, 80(8), 1180-1189. https://doi.org/10.1016/j.bcp.2010.06.041

The adenosine A(1) receptor is a promising therapeutic target for neurological disorders such as cognition deficits and is involved in cardiovascular preconditioning. Classically adenosine receptor agonists were all derivatives of adenosine, and thou... Read More about Characterization of [3H]LUF5834: A novel non-ribose high-affinity agonist radioligand for the adenosine A1 receptor.

Gender in campus incubation: evidence from Ireland (2010)
Journal Article
Treanor, L., & Henry, C. (2010). Gender in campus incubation: evidence from Ireland. International Journal of Gender and Entrepreneurship, 2(2), 130-149. https://doi.org/10.1108/17566261011051008

Purpose
Women entrepreneurs face gender‐specific barriers surrounding access to: networks of information, assistance, finance and investment funds, in addition to socio‐cultural barriers. Business incubation literature indicates the supports provide... Read More about Gender in campus incubation: evidence from Ireland.

Human leucine-rich repeat proteins: A genome-wide bioinformatic categorization and functional analysis in innate immunity (2010)
Journal Article
Ng, A. C., Eisenberg, J. M., Heath, R. J., Huett, A., Robinson, C. M., Nau, G. J., & Xavier, R. J. (2011). Human leucine-rich repeat proteins: A genome-wide bioinformatic categorization and functional analysis in innate immunity. Proceedings of the National Academy of Sciences, 108(SUPPL. 1), 4631-4638. https://doi.org/10.1073/pnas.1000093107

In innate immune sensing, the detection of pathogen-associated molecular patterns by recognition receptors typically involve leucine-rich repeats (LRRs). We provide a categorization of 375 human LRR-containing proteins, almost half of which lack othe... Read More about Human leucine-rich repeat proteins: A genome-wide bioinformatic categorization and functional analysis in innate immunity.

LIM-domain proteins, LIMD1, Ajuba, and WTIP are required for microRNA-mediated gene silencing (2010)
Journal Article
James, V., Zhang, Y., Foxler, D. E., de Moor, C. H., Kong, Y. W., Webb, T. M., …Sharp, T. V. (2010). LIM-domain proteins, LIMD1, Ajuba, and WTIP are required for microRNA-mediated gene silencing. Proceedings of the National Academy of Sciences, 107(28), 12499-12504. https://doi.org/10.1073/pnas.0914987107

In recent years there have been major advances with respect to the identification of the protein components and mechanisms of microRNA (miRNA) mediated silencing. However, the complete and precise repertoire of components and mechanism(s) of action r... Read More about LIM-domain proteins, LIMD1, Ajuba, and WTIP are required for microRNA-mediated gene silencing.

Regulation of neurotoxin production and sporulation by a putative agrBD signaling system in proteolytic Clostridium botulinum (2010)
Journal Article
Cooksley, C. M., Davis, I. J., Winzer, K., Chan, W. C., Peck, M. W., & Minton, N. P. (2010). Regulation of neurotoxin production and sporulation by a putative agrBD signaling system in proteolytic Clostridium botulinum. Applied and Environmental Microbiology, 76(13), 4448-4460. https://doi.org/10.1128/AEM.03038-09

A significant number of genome sequences of Clostridium botulinum and related species have now been determined. In silico analysis of these data revealed the presence of two distinct agr loci (agr-1 and agr-2) in all group I strains, each encoding pu... Read More about Regulation of neurotoxin production and sporulation by a putative agrBD signaling system in proteolytic Clostridium botulinum.

A genetic programming hyper-heuristic approach for evolving 2-D strip packing heuristics (2010)
Journal Article
Burke, E. K., Hyde, M., Kendall, G., & Woodward, J. (2010). A genetic programming hyper-heuristic approach for evolving 2-D strip packing heuristics. IEEE Transactions on Evolutionary Computation, 14(6), https://doi.org/10.1109/tevc.2010.2041061

We present a genetic programming (GP) system to evolve reusable heuristics for the 2-D strip packing problem. The evolved heuristics are constructive, and decide both which piece to pack next and where to place that piece, given the current partial s... Read More about A genetic programming hyper-heuristic approach for evolving 2-D strip packing heuristics.

Hybrid cascaded multilevel converter with integrated series Active Power Filter for interfacing energy storage system to medium voltage grid (2010)
Presentation / Conference Contribution
Rashed, M., Klumpner, C., & Asher, G. (2010). Hybrid cascaded multilevel converter with integrated series Active Power Filter for interfacing energy storage system to medium voltage grid. In The 2010 International Power Electronics Conference - ECCE ASIA -. https://doi.org/10.1109/IPEC.2010.5543461

This paper presents a new control strategy for a high performance hybrid cascaded H-Bridge HB multilevel converter with integrated series Active Power Filter Stage APFS. Unequal DC voltage sources are used to energise the converter's HBs. This offers... Read More about Hybrid cascaded multilevel converter with integrated series Active Power Filter for interfacing energy storage system to medium voltage grid.

The fate of steroid estrogens: Partitioning during wastewater treatment and onto river sediments (2010)
Journal Article
Gomes, R. L., Scrimshaw, M. D., Cartmell, E., & Lester, J. N. (2010). The fate of steroid estrogens: Partitioning during wastewater treatment and onto river sediments. Environmental Monitoring and Assessment, 175, 431–441. https://doi.org/10.1007/s10661-010-1541-1

The partitioning of steroid estrogens in wastewater treatment and receiving waters is likely to influence their discharge to, and persistence in, the environment. This study investigated the partitioning behaviour of steroid estrogens in both laborat... Read More about The fate of steroid estrogens: Partitioning during wastewater treatment and onto river sediments.