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All Outputs (228)

Suberin plasticity to developmental and exogenous cues is regulated by a set of MYB transcription factors (2020)
Preprint / Working Paper
Shukla, V., Han, J., Cléard, F., Legendre-Lefebvre, L., Gully, K., Flis, P., …Barberon, M. Suberin plasticity to developmental and exogenous cues is regulated by a set of MYB transcription factors

Suberin is a hydrophobic biopolymer that can be deposited at the periphery of cells, forming protective barriers against biotic and abiotic stress. In roots, suberin forms lamellae at the periphery of endodermal cells where it plays crucial roles in... Read More about Suberin plasticity to developmental and exogenous cues is regulated by a set of MYB transcription factors.

Self-activated photoblinking of nitrogen vacancy centers in nanodiamonds (sandSTORM): A method for rapid single molecule localization microscopy with unlimited observation time (2020)
Preprint / Working Paper
Narayanasamy, K. K., Price, J. C., Mesquita-Riberio, R., Mather, M. L., & Jayasinghe, I. Self-activated photoblinking of nitrogen vacancy centers in nanodiamonds (sandSTORM): A method for rapid single molecule localization microscopy with unlimited observation time

Stochastic optical reconstruction microscopy (STORM) is one of the most commonly used super-resolution microscopy techniques. Popular implementations of STORM utilize aromatic fluorophores and consist of a number of intrinsic limitations such the fin... Read More about Self-activated photoblinking of nitrogen vacancy centers in nanodiamonds (sandSTORM): A method for rapid single molecule localization microscopy with unlimited observation time.

Microrheology reveals microscale viscosity gradients in planktonic systems (2020)
Preprint / Working Paper
Guadayol, Ò., Mendonca, T., Segura-Noguera, M., Wright, A. J., Tassieri, M., & Humphries, S. Microrheology reveals microscale viscosity gradients in planktonic systems

Microbial activity in planktonic systems creates a dynamic and heterogeneous microscale seascape that harbours a diverse community of microorganisms and ecological interactions of global significance. In recent decades a great effort has been put int... Read More about Microrheology reveals microscale viscosity gradients in planktonic systems.

The spatial percept of tinnitus is associated with hearing asymmetry: subgroup comparisons (2020)
Preprint / Working Paper
Genitsaridi, E., Kypraios, T., Edvall, N. K., Trpchevska, N., Canlon, B., Hoare, D. J., …Hall, D. A. The spatial percept of tinnitus is associated with hearing asymmetry: subgroup comparisons

The spatial percept of tinnitus is hypothesized as an important variable for tinnitus subtyping. Hearing asymmetry often associates with tinnitus laterality, but not always. One of the methodological limitations for cross-study comparisons is how the... Read More about The spatial percept of tinnitus is associated with hearing asymmetry: subgroup comparisons.

Unpacking the Allee effect: determining individual-level mechanisms that drive global population dynamics (2020)
Preprint / Working Paper
Fadai, N. T., Johnston, S. T., & Simpson, M. J. Unpacking the Allee effect: determining individual-level mechanisms that drive global population dynamics

We present a solid theoretical foundation for interpreting the origin of Allee effects by providing the missing link in understanding how local individual-based mechanisms translate to global population dynamics. Allee effects were originally propose... Read More about Unpacking the Allee effect: determining individual-level mechanisms that drive global population dynamics.

Inhibition of neuroinflammatory nitric oxide signalling supresses protein glycation and recovers neuronal dysfunction in prion disease (2020)
Preprint / Working Paper
Bourgognon, J.-M., Spiers, J. G., Robinson, S., Scheiblich, H., Ortori, C., Bradley, S. J., …Steinert, J. Inhibition of neuroinflammatory nitric oxide signalling supresses protein glycation and recovers neuronal dysfunction in prion disease

Background: Several neurodegenerative diseases associated with protein misfolding (Alzheimer’s, Parkinson’s disease) exhibit oxidative and nitrergic stress following initiation of neuroinflammatory pathways. Associated nitric oxide (NO)-mediated post... Read More about Inhibition of neuroinflammatory nitric oxide signalling supresses protein glycation and recovers neuronal dysfunction in prion disease.

A randomised controlled trial to assess the effectiveness and cost-effectiveness of tailored web- and text-based smoking cessation support in primary care: iQuit in Practice II trial protocol (Preprint) (2020)
Preprint / Working Paper
Proctor, J., Naughton, F., Sloan, M., Hopewell, S., Brimicombe, J., Prevost, T., …Sutton, S. A randomised controlled trial to assess the effectiveness and cost-effectiveness of tailored web- and text-based smoking cessation support in primary care: iQuit in Practice II trial protocol (Preprint)

Background: The prevalence of smoking is in decline, however, it continues to be a major public health burden. In England, primary care is the health setting that provides smoking cessation support to the most smokers. However, this setting has one o... Read More about A randomised controlled trial to assess the effectiveness and cost-effectiveness of tailored web- and text-based smoking cessation support in primary care: iQuit in Practice II trial protocol (Preprint).

A novel allele of ASY3 promotes meiotic stability in autotetraploid Arabidopsis lyrata (2020)
Preprint / Working Paper
Seear, P. J., France, M. G., Gregory, C. L., Heavens, D., Schmickl, R., Yant, L., & Higgins, J. D. A novel allele of ASY3 promotes meiotic stability in autotetraploid Arabidopsis lyrata

In this study we performed a genotype-phenotype association analysis of meiotic stability in ten autotetraploid Arabidopsis lyrata and A. lyrata/A. arenosa hybrid populations collected from the Wachau region and East Austrian Forealps. The aim was to... Read More about A novel allele of ASY3 promotes meiotic stability in autotetraploid Arabidopsis lyrata.

Commercial Law Intersections (2020)
Preprint / Working Paper
Castellano, G., & Tosato, A. (2020). Commercial Law Intersections

Commercial law is not a single, monolithic entity. It has grown into a dense thicket of subject-specific branches that govern a broad range of transactions and corporate actions. When one of such dealings or activities falls concurrently within the p... Read More about Commercial Law Intersections.

Improving the Involvement of People with Dementia in Developing Technology–Based Interventions: a Narrative Synthesis Review and Best Practice Guidelines (Preprint) (2020)
Preprint / Working Paper
Rai, H. K., Cavalcanti Barroso, A., Yates, L., Schneider, J., & Orrell, M. Improving the Involvement of People with Dementia in Developing Technology–Based Interventions: a Narrative Synthesis Review and Best Practice Guidelines (Preprint)

Background: Technology can be helpful in supporting people with dementia in their daily lives. However, people with dementia are often not fully involved in the development process of new technology. This lack of involvement of people with dementia... Read More about Improving the Involvement of People with Dementia in Developing Technology–Based Interventions: a Narrative Synthesis Review and Best Practice Guidelines (Preprint).

The Iso2k Database: A global compilation of paleo-δ18O and δ2H records to aid understanding of Common Era climate (2020)
Preprint / Working Paper
Konecky, B. L., McKay, N. P., Churakova (Sidorova), O. V., Comas-Bru, L., Dassié, E. P., DeLong, K. L., …von Gunten, L. The Iso2k Database: A global compilation of paleo-δ18O and δ2H records to aid understanding of Common Era climate

Reconstructions of global hydroclimate during the Common Era (CE; the past ~ 2000 years) are important for providing context for current and future global environmental change. Stable isotope ratios in water are quantitative indicators of hydroclimat... Read More about The Iso2k Database: A global compilation of paleo-δ18O and δ2H records to aid understanding of Common Era climate.

The role of the cingulate cortex in the generation of motor tics and the experience of the premonitory urge-to-tic in Tourette syndrome (2020)
Preprint / Working Paper
Jackson, S. R., Sigurdsson, H. P., Dyke, K., Condon, M., & Jackson, G. M. The role of the cingulate cortex in the generation of motor tics and the experience of the premonitory urge-to-tic in Tourette syndrome

Tourette syndrome (TS) is a neurological disorder of childhood onset that is characterised by the occurrence of motor and vocal tics. TS is associated with cortical-striatal-thalamic-cortical circuit [CSTC] dysfunction and hyper-excitability of corti... Read More about The role of the cingulate cortex in the generation of motor tics and the experience of the premonitory urge-to-tic in Tourette syndrome.

Using digitally augmented objects to reduce sedentary behavior in office workers: design and development of the WorkMyWay intervention (2020)
Preprint / Working Paper
Huang, Y., Price, D., Benford, S., & Blake, H. Using digitally augmented objects to reduce sedentary behavior in office workers: design and development of the WorkMyWay intervention

Background: Sedentary behavior (SB) is associated with various adverse health outcomes. The prevalence of prolonged sitting at work among office workers makes a case for SB interventions to target this setting and population. Everyday mundane obje... Read More about Using digitally augmented objects to reduce sedentary behavior in office workers: design and development of the WorkMyWay intervention.

Using digitally augmented objects to reduce sedentary behavior in office workers: design and development of the WorkMyWay intervention (2020)
Preprint / Working Paper
Huang, Y., Price, D., Benford, S., Patel, R., & Blake, H. Using digitally augmented objects to reduce sedentary behavior in office workers: design and development of the WorkMyWay intervention

Background: Sedentary behavior (SB) is associated with various adverse health outcomes. The prevalence of prolonged sitting at work among office workers makes a case for SB interventions to target this setting and population. Everyday mundane obje... Read More about Using digitally augmented objects to reduce sedentary behavior in office workers: design and development of the WorkMyWay intervention.

Policy Effects of International Taxation on Firm Dynamics and Capital Structure (2020)
Preprint / Working Paper
Spencer, A. Policy Effects of International Taxation on Firm Dynamics and Capital Structure

This paper develops a quantitative open economy framework with dynamics, firm heterogeneity and financial frictions to study the impact of corporate tax reforms targeted at multinationals. The model quantifies their impact on productivity, GDP and we... Read More about Policy Effects of International Taxation on Firm Dynamics and Capital Structure.

The impact of algorithmic decision-making processes on young people’s well-being (Preprint) (2019)
Preprint / Working Paper
Perez Vallejos, E., Dowthwaite, L., Creswich, H., Portillo, V., Koene, A., Jirotka, M., …McAuley, D. The impact of algorithmic decision-making processes on young people’s well-being (Preprint)

Background: Algorithms rule the online environments and are essential for performing data processing, filtering, personalisation and other tasks. Research has shown that children and young people make up a significant proportion of Internet users, h... Read More about The impact of algorithmic decision-making processes on young people’s well-being (Preprint).

Development of bioactive electrospun scaffolds suitable to support skin fibroblasts and release Lucilia sericata maggot excretion/secretion (2019)
Preprint / Working Paper
Giacaman, A. G., Styliari, I. D., Taresco, V., Pritchard, D., Alexander, C., & Rose, F. R. Development of bioactive electrospun scaffolds suitable to support skin fibroblasts and release Lucilia sericata maggot excretion/secretion

Larval therapy has been reported to exert beneficial actions upon chronic wound healing by promoting granulation tissue formation, antimicrobial activity and degrading necrotic tissue. However, the use of live maggots is problematic for patient accep... Read More about Development of bioactive electrospun scaffolds suitable to support skin fibroblasts and release Lucilia sericata maggot excretion/secretion.

Coinfinder: Detecting Significant Associations and Dissociations in Pangenomes (2019)
Preprint / Working Paper
Whelan, F. J., Rusilowicz, M., & McInerney, J. O. Coinfinder: Detecting Significant Associations and Dissociations in Pangenomes

The accessory genes of prokaryote and eukaryote pangenomes accumulate by horizontal gene transfer, differential gene loss, and the effects of selection and drift. We have developed Coinfinder, a software program that assesses whether sets of homologo... Read More about Coinfinder: Detecting Significant Associations and Dissociations in Pangenomes.

A randomised controlled trial to assess the effectiveness and cost-effectiveness of tailored web- and text-based smoking cessation support in primary care: iQuit in Practice II trial protocol (2019)
Preprint / Working Paper
Proctor, J., Naughton, F., Sloan, M., Hopewell, S., Brimicombe, J., Prevost, A. T., …Sutton, S. A randomised controlled trial to assess the effectiveness and cost-effectiveness of tailored web- and text-based smoking cessation support in primary care: iQuit in Practice II trial protocol