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New treatments for atopic dermatitis (2002)
Journal Article
Williams, H. (2002). New treatments for atopic dermatitis. British medical journal, 324,

Atopic dermatitis now affects 15% to 20% of chil­dren in developed countries, and prevalence in cities in developing countries undergoingrapid demographic changes is quickly following suit. [1] Most cases of atopic dermatitis in a given communityare... Read More about New treatments for atopic dermatitis.

Local variation in endoparasite intensities of bank voles (Clethrionomys glareolus )from ecologically similar sites: morphometric and endocrine correlates (2002)
Journal Article
Barnard, C., Behnke, J., Bajer, A., Bray, D., Race, T., Frake, K., …Sinski, E. (2002). Local variation in endoparasite intensities of bank voles (Clethrionomys glareolus )from ecologically similar sites: morphometric and endocrine correlates. Journal of Helminthology, 76(2), https://doi.org/10.1079/JOH2001109

Much interest has centred recently on the role of adaptive trade-offs between the immune system and other components of life history in determining resistance and parasite intensities among hosts. Steroid hormones, particularly glucocorticoids and se... Read More about Local variation in endoparasite intensities of bank voles (Clethrionomys glareolus )from ecologically similar sites: morphometric and endocrine correlates.

A molecular phylogeny of nuclear and mitochondrial sequences in Hymenolepis nana (Cestoda) supports the existence of a cryptic species (2002)
Journal Article
MacNish, M., Morgan-Ryan, U., Monis, P., Behnke, J., & Thompson, R. (2002). A molecular phylogeny of nuclear and mitochondrial sequences in Hymenolepis nana (Cestoda) supports the existence of a cryptic species. Parasitology, 125(6), https://doi.org/10.1017/S0031182002002366

Since isolates of Hymenolepis nana infecting humans and rodents are morphologically indistinguishable, the only way they can be reliably identified is by comparing the parasite in each host using molecular tools. In the current study, isolates of H.... Read More about A molecular phylogeny of nuclear and mitochondrial sequences in Hymenolepis nana (Cestoda) supports the existence of a cryptic species.

Homochiral 4-azalysine building blocks: Syntheses and applications in solid-phase chemistry (2002)
Journal Article
Chhabra, S. R., Mahajan, A., & Chan, W. C. (2002). Homochiral 4-azalysine building blocks: Syntheses and applications in solid-phase chemistry. Journal of Organic Chemistry, 67(12), 4017-4029. https://doi.org/10.1021/jo010456e

Anomalous amino acids not only play central roles as mimics of natural amino acids but also offer opportunities as unique building blocks for combinatorial chemistry. This paper describes the chiral syntheses and solid-phase applications of a versati... Read More about Homochiral 4-azalysine building blocks: Syntheses and applications in solid-phase chemistry.

Human T cells that have been conditioned by the proteolytic activity of the major dust mite allergen Der p 1 trigger enhanced immunoglobulin E synthesis by B cells (2002)
Journal Article
Ghaemmaghami, A. M., & Shakib, F. (2002). Human T cells that have been conditioned by the proteolytic activity of the major dust mite allergen Der p 1 trigger enhanced immunoglobulin E synthesis by B cells. Clinical and Experimental Allergy, 32(5), 728-732. https://doi.org/10.1046/j.1365-2222.2002.01374.x

Background: We have previously demonstrated that the proteolytic activity of Der p 1 selectively cleaves human CD25, the 55 kDa α subunit of the IL-2 receptor. As a result of cleavage of surface CD25, peripheral blood T cells produce less IFN-γ and m... Read More about Human T cells that have been conditioned by the proteolytic activity of the major dust mite allergen Der p 1 trigger enhanced immunoglobulin E synthesis by B cells.

Characterization of the Campylobacter jejuni Heptosyltransferase II Gene, waaF, Provides Genetic Evidence that Extracellular Polysaccharide Is Lipid A Core Independent (2002)
Journal Article
Oldfield, N. J., Moran, A. P., Millar, L. A., Prendergast, M. M., & Ketley, J. M. (2002). Characterization of the Campylobacter jejuni Heptosyltransferase II Gene, waaF, Provides Genetic Evidence that Extracellular Polysaccharide Is Lipid A Core Independent. Journal of Bacteriology, 184(8), 2100-2107. https://doi.org/10.1128/JB.184.8.2100-2107.2002

Campylobacter jejuni produces both lipooligosaccharide (LOS) and a higher-molecular-weight polysaccharide that is believed to form a capsule. The role of these surface polysaccharides in C jejuni-mediated enteric disease is unclear; however, epitopes... Read More about Characterization of the Campylobacter jejuni Heptosyltransferase II Gene, waaF, Provides Genetic Evidence that Extracellular Polysaccharide Is Lipid A Core Independent.

The interleukin-10 – 1082 G/A polymorphism: allele frequency in different populations and functional significance (2002)
Journal Article
Rees, L., Wood, N., Gillespie, K., Lai, K., Gaston, K., & Mathieson, P. (2002). The interleukin-10 – 1082 G/A polymorphism: allele frequency in different populations and functional significance. Cellular and Molecular Life Sciences, 59(3), 560-569. https://doi.org/10.1007/s00018-002-8448-0

Genotypic variation in the human interleukin-10 (IL-10) promoter may account for marked inter-individual variation in IL-10 production and may influence susceptibility to autoimmune diseases. The G/A polymorphism at position -1082 has been linked to... Read More about The interleukin-10 – 1082 G/A polymorphism: allele frequency in different populations and functional significance.

Randomised controlled trial of short bursts of a potent topical corticosteroid versus prolonged use of a mild preparation for children with mild or moderate atopic eczema (2002)
Journal Article
Thomas, K., Armstrong, S., Avery, A., Li Wan Po, A., O'Neill, C., Young, S., & Williams, H. (2002). Randomised controlled trial of short bursts of a potent topical corticosteroid versus prolonged use of a mild preparation for children with mild or moderate atopic eczema. British medical journal, 324(7340),

Objective To determine whether a three day burst of
a potent corticosteroid is more effective than a mild
preparation used for seven days in children with mild
or moderate atopic eczema.
Design Randomised, double blind, parallel group
study of 1... Read More about Randomised controlled trial of short bursts of a potent topical corticosteroid versus prolonged use of a mild preparation for children with mild or moderate atopic eczema.

Failure to infect laboratory rodent hosts with human isolates of Rodentolepis(= Hymenolepis) nana (2002)
Journal Article
MacNish, M., Morgan, U., Behnke, J. M., & Thompson, R. (2002). Failure to infect laboratory rodent hosts with human isolates of Rodentolepis(= Hymenolepis) nana. Journal of Helminthology, 76(1), https://doi.org/10.1079/JOH200198

Confusion exists over the species status and host-specificity of the tapeworm Rodentolepis (= Hymenolepis) nana. It has been described as one species, R. nana, found in both humans and rodents. Others have identified a subspecies; R. nana var. frater... Read More about Failure to infect laboratory rodent hosts with human isolates of Rodentolepis(= Hymenolepis) nana.

Indices of heart rate variability and performance during a response-conflict task are differently associated with ADHD and autism (2002)
Journal Article
Bellato, A., Arora, I., Kochhar, P., Hollis, C., & Groom, M. J. (2002). Indices of heart rate variability and performance during a response-conflict task are differently associated with ADHD and autism. Journal of Attention Disorders, 26(3), 434-446. https://doi.org/10.1177/1087054720972793

Objective. We investigated autonomic arousal, attention and response conflict, in ADHD and autism.

Method. Heart rate variability (HRV), and behavioural and electrophysiological indices of performance, were recorded during a task with low and hig... Read More about Indices of heart rate variability and performance during a response-conflict task are differently associated with ADHD and autism.

Predicting arsenic solubility in contaminated soils using isotopic dilution techniques (2002)
Journal Article
Tye, A. M., Young, S. D., Crout, N. M., Zhang, H., Preston, S., Bailey, E. H., …Kilham, K. (2002). Predicting arsenic solubility in contaminated soils using isotopic dilution techniques. Environmental Science and Technology, 36(5), 982-988. https://doi.org/10.1021/es0101633

An isotopic dilution assay was developed to measure radiolabile As concentration in a diverse range of soils (pH 3.30-7.62; % C = 1.00-6.55). Soils amended with 50 mg of As kg-1 (as Na2HAsO4·7H2O) were incubated for over 800 d in an aerated "microcos... Read More about Predicting arsenic solubility in contaminated soils using isotopic dilution techniques.

An indirect genetic algorithm for set covering problems (2002)
Journal Article
Aickelin, U. (2002). An indirect genetic algorithm for set covering problems. Journal of the Operational Research Society, 53(10), 1118-1126. https://doi.org/10.1057/palgrave.jors.2601317

This paper presents a new type of genetic algorithm for the set covering problem. It differs from previous evolutionary approaches first because it is an indirect algorithm, i.e. the actual solutions are found by an external decoder function. The gen... Read More about An indirect genetic algorithm for set covering problems.

'Enhanced Direct and Indirect Genetic Algorithm Approaches for a Mall Layout and Tenant Selection Problem' (2002)
Journal Article
Aickelin, U., & Dowsland, K. (2002). 'Enhanced Direct and Indirect Genetic Algorithm Approaches for a Mall Layout and Tenant Selection Problem'. Journal of Heuristics, 8(5), https://doi.org/10.1023/A%3A1016536623961

During our earlier research, it was recognised that in order to be successful with an indirect genetic algorithm approach using a decoder, the decoder has to strike a balance between being an optimiser in its own right and finding feasible solutions.... Read More about 'Enhanced Direct and Indirect Genetic Algorithm Approaches for a Mall Layout and Tenant Selection Problem'.

Prevalence and abundance of Cryptosporidium parvum and Giardia spp. in wild rural rodents from the Mazury Lake District region of Poland (2002)
Journal Article
Bajer, A., Bednarska, M., Pawelczyk, A., Behnke, J. M., Gilbert, F. S., & Sinski, E. (2002). Prevalence and abundance of Cryptosporidium parvum and Giardia spp. in wild rural rodents from the Mazury Lake District region of Poland. Parasitology, 125(1), https://doi.org/10.1017/S0031182002001865

Prevalence and abundance of Cryptosporodium parvum and Giardia spp. were studied in 3 species of rodents from forests and abandoned agricultural fields in N.E. Poland (Clethrionomys glareolus n=459; Microtus arvalis n=274; Apodemus flavicollis n=209)... Read More about Prevalence and abundance of Cryptosporidium parvum and Giardia spp. in wild rural rodents from the Mazury Lake District region of Poland.

In vivo models of lung neutrophil activation. Comparison of mice and hamsters (2002)
Journal Article
Corteling, R., Wyss, D., & Trifilieff, A. (2002). In vivo models of lung neutrophil activation. Comparison of mice and hamsters. BMC Pharmacology, 2(1),

BACKGROUND: Evidence suggests that both the migration and activation of neutrophils into the airway is of importance in pathological conditions such as pulmonary emphysema. In the present study, we describe in vivo models of lung neutrophil infiltrat... Read More about In vivo models of lung neutrophil activation. Comparison of mice and hamsters.

Pharmacogenetics, pharmacogenomics and airway disease (2002)
Journal Article
Hall, I. P. (2002). Pharmacogenetics, pharmacogenomics and airway disease. Respiratory Research, 3(1),

The availability of a draft sequence for the human genome will revolutionise research into airway disease. This review deals with two of the most important areas impinging on the treatment of patients: pharmacogenetics and pharmacogenomics. Considera... Read More about Pharmacogenetics, pharmacogenomics and airway disease.

Using Needs Assessment to Understand Continuing Disability in Patients with Enduring Mental Illness. Implications for Considerations of Service Development (2002)
Journal Article
Middleton, H., Adeniran, R., Brewin, C. R., Brady, C., Duggan, C., Hopkins, N., …Walton, M. (2002). Using Needs Assessment to Understand Continuing Disability in Patients with Enduring Mental Illness. Implications for Considerations of Service Development. Journal of Mental Health, 11,

Particular strengths of the MRC Needs for Care Assessment Schedule have been used to investigate the treatment status of patients with persistent psychiatric disability in ways that other needs assessment tools are unable to. One hundred and seventy-... Read More about Using Needs Assessment to Understand Continuing Disability in Patients with Enduring Mental Illness. Implications for Considerations of Service Development.