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In vitro anthelmintic effects of cysteine proteinases from plants against intestinal helminths of rodents (2007)
Journal Article
Stepek, G., Lowe, A. E., Buttle, D. J., Duce, I. R., & Behnke, J. M. (2007). In vitro anthelmintic effects of cysteine proteinases from plants against intestinal helminths of rodents. Journal of Helminthology, 81(4), https://doi.org/10.1017/S0022149X0786408X

Infections with gastrointestinal (GI) nematodes are amongst the most prevalent worldwide, especially in tropical climates. Control of these infections is primarily through treatment with anthelmintic drugs, but the rapid development of resistance to... Read More about In vitro anthelmintic effects of cysteine proteinases from plants against intestinal helminths of rodents.

Can open access repositories and peer-reviewed journals coexist? (2007)
Journal Article
Pinfield, S. (2007). Can open access repositories and peer-reviewed journals coexist?. Serials, 20(3),

It is often assumed that open access repositories and peer-reviewed journals are in competition with each other and therefore will in the long term be unable to coexist. This paper takes a critical look at that assumption. It draws on the available e... Read More about Can open access repositories and peer-reviewed journals coexist?.

Modeling electrocortical activity through improved local approximations of integral neural field equations (2007)
Journal Article
Coombes, S., Venkov, N., Shiau, L., Bojak, I., Liley, D., & Laing, C. (2007). Modeling electrocortical activity through improved local approximations of integral neural field equations. Physical Review E, 76(5), https://doi.org/10.1103/PhysRevE.76.051901

Neural field models of firing rate activity typically take the form of integral equations with space-dependent axonal delays. Under natural assumptions on the synaptic connectivity we show how one can derive an equivalent partial differential equatio... Read More about Modeling electrocortical activity through improved local approximations of integral neural field equations.

Determination of the human antibody response to the epitope defined by the hepatitis C virus-neutralizing monoclonal antibody AP33 (2007)
Journal Article
Tarr, A. W., Owsianka, A. M., Jayaraj, D., Brown, R. J., Hickling, T. P., Irving, W. L., …Ball, J. K. (2007). Determination of the human antibody response to the epitope defined by the hepatitis C virus-neutralizing monoclonal antibody AP33. Journal of General Virology, 88(11), 2991-3001. https://doi.org/10.1099/vir.0.83065-0

Hepatitis C virus (HCV) is a major cause of liver disease worldwide and there is a pressing need for the development of a preventative vaccine as well as new treatments. It was recently demonstrated that the mouse monoclonal antibody (mAb) AP33 poten... Read More about Determination of the human antibody response to the epitope defined by the hepatitis C virus-neutralizing monoclonal antibody AP33.

Molecular phylogeny of the helicoid land snails (Pulmonata: Stylommatophora: Helicoidea), with special emphasis on the Camaenidae (2007)
Journal Article
Wade, C. M., Hudelot, C., Davison, A., Naggs, F., & Mordan, P. B. (2007). Molecular phylogeny of the helicoid land snails (Pulmonata: Stylommatophora: Helicoidea), with special emphasis on the Camaenidae. Journal of Molluscan Studies, 73(4), 411-415. https://doi.org/10.1093/mollus/eym030

The superfamily Helicoidea is a large and diverse group of land snails belonging to the Pulmonate suborder Stylommatophora. It has an almost worldwide distribution, absent from only sub-Saharan Africa, southern South America, New Zealand and some Pac... Read More about Molecular phylogeny of the helicoid land snails (Pulmonata: Stylommatophora: Helicoidea), with special emphasis on the Camaenidae.

Social Regulation in the Air Transport Industry – An Examination of Regulation 1107/2006 concerning the Rights of Disabled Persons and Persons with Reduced Mobility when travelling by Air (2007)
Journal Article
Varney, E. (2007). Social Regulation in the Air Transport Industry – An Examination of Regulation 1107/2006 concerning the Rights of Disabled Persons and Persons with Reduced Mobility when travelling by Air. Zeitschrift für Rechtssoziologie, 28(2), 191-201. https://doi.org/10.1515/zfrs-2007-0208

The regulation of the air transport industry has implications for individuals not just in their capacity as consumers, but also as citizens. Transport goes beyond the mere provision of an economic service and enables us to be actively involved in eco... Read More about Social Regulation in the Air Transport Industry – An Examination of Regulation 1107/2006 concerning the Rights of Disabled Persons and Persons with Reduced Mobility when travelling by Air.

A closer look at using quasar near-zones as a probe of neutral hydrogen in the intergalactic medium (2007)
Journal Article
S. Bolton, J., & G. Haehnelt, M. (2007). A closer look at using quasar near-zones as a probe of neutral hydrogen in the intergalactic medium. Monthly Notices of the Royal Astronomical Society: Letters, 381(1), L35-L39. https://doi.org/10.1111/j.1745-3933.2007.00361.x

We examine a large set of synthetic quasar spectra to realistically assess the potential of using the relative sizes of highly ionized near-zones in the Lya and Lyb forest as a probe of the neutral hydrogen content of the intergalactic medium (IGM) a... Read More about A closer look at using quasar near-zones as a probe of neutral hydrogen in the intergalactic medium.

The observed ionization rate of the intergalactic medium and the ionizing emissivity at z >5: Evidence for a photon starved and extended epoch of reionization (2007)
Journal Article
S. Bolton, J., & G. Haehnelt, M. (2007). The observed ionization rate of the intergalactic medium and the ionizing emissivity at z >5: Evidence for a photon starved and extended epoch of reionization. Monthly Notices of the Royal Astronomical Society, 382(1), 325–341. https://doi.org/10.1111/j.1365-2966.2007.12372.x

We use a large set of hydrodynamical simulations, combined with measurements of the Lyman alpha opacity of the IGM taken from the literature, to obtain robust estimates for the photoionization rate per hydrogen atom at z=5 and 6. We find the photoion... Read More about The observed ionization rate of the intergalactic medium and the ionizing emissivity at z >5: Evidence for a photon starved and extended epoch of reionization.

Bumps and rings in a two-dimensional neural field: splitting and rotational instabilities (2007)
Journal Article
Owen, M. R., Laing, C., & Coombes, S. (2007). Bumps and rings in a two-dimensional neural field: splitting and rotational instabilities. New Journal of Physics, 9(378), https://doi.org/10.1088/1367-2630/9/10/378

In this paper we consider instabilities of localised solutions in planar neural field firing rate models of Wilson-Cowan or Amari type. Importantly we show that angular perturbations can destabilise spatially localised solutions. For a scalar model... Read More about Bumps and rings in a two-dimensional neural field: splitting and rotational instabilities.

Sensing Danger: Innate Immunology for Intrusion Detection (2007)
Journal Article
Aickelin, U., & Greensmith, J. (2007). Sensing Danger: Innate Immunology for Intrusion Detection. Information Security Technical Report, 12(4), 218-227. https://doi.org/10.1016/j.istr.2007.10.003

The immune system provides an ideal metaphor for anomaly detection in general and computer security in particular. Based on this idea, artificial immune systems have been used for a number of years for intrusion detection, unfortunately so far with l... Read More about Sensing Danger: Innate Immunology for Intrusion Detection.

The small subunit (SSU) ribosomal (r) RNA gene as a genetic marker for identifying infective 3rd juvenile stage Angiostrongylus cantonensis (2007)
Journal Article
Fontanilla, I. K., & Wade, C. M. (2008). The small subunit (SSU) ribosomal (r) RNA gene as a genetic marker for identifying infective 3rd juvenile stage Angiostrongylus cantonensis. Acta Tropica, 105(2), 181-186. https://doi.org/10.1016/j.actatropica.2007.10.007

We have developed a molecular method using PCR-direct sequencing to identify the infective 3rd juvenile stage of Angiostrongylus cantonensis, a nematode parasite of rodents that can accidentally infect humans and cause eosinophilic meningitis. We dem... Read More about The small subunit (SSU) ribosomal (r) RNA gene as a genetic marker for identifying infective 3rd juvenile stage Angiostrongylus cantonensis.

P-glycoprotein is downregulated in KG1a-primitive leukemia cells by LDL cholesterol deprivation and by HMG-CoA reductase inhibitors (2007)
Journal Article
Connelly Smith, L., Pattinson, J., Grundy, M., Shang, S., Seedhouse, C., Russell, N., & Pallis, M. (2007). P-glycoprotein is downregulated in KG1a-primitive leukemia cells by LDL cholesterol deprivation and by HMG-CoA reductase inhibitors. Experimental Hematology, 35(12), 1793-1800. https://doi.org/10.1016/j.exphem.2007.07.017

Objective
P-glycoprotein (pgp) is a membrane transporter encoded by the multidrug resistance (MDR1, ABCB1) gene. Pgp is a poor prognostic factor in elderly patients with acute myeloid leukemia (AML). In addition to its role in drug efflux, pgp has b... Read More about P-glycoprotein is downregulated in KG1a-primitive leukemia cells by LDL cholesterol deprivation and by HMG-CoA reductase inhibitors.

Multiphoton imaging of chick retinal development in relation to gap junctional communication (2007)
Journal Article
Becker, D. L., Webb, K. F., Thrasivoulou, C., Lin, C. C., Nadershahi, R., Tsakiri, N., & Cook, J. E. (2007). Multiphoton imaging of chick retinal development in relation to gap junctional communication. Journal of Physiology, 585(3), 711-719. https://doi.org/10.1113/jphysiol.2007.138776

Neural progenitor cells in the developing retina extend processes that stretch from the basal vitread surface to the apical ventricular surface. During the cell cycle, the nucleus undergoes interkinetic nuclear migration (INM), moving in a vitread di... Read More about Multiphoton imaging of chick retinal development in relation to gap junctional communication.

Human combinatorial libraries yield rare antibodies that broadly neutralize hepatitis C virus (2007)
Journal Article
Johansson, D. X., Voisset, C., Tarr, A. W., Aung, M., Ball, J. K., Dubuisson, J., & Persson, M. A. (2007). Human combinatorial libraries yield rare antibodies that broadly neutralize hepatitis C virus. Proceedings of the National Academy of Sciences, 104(41), 16269-16274. https://doi.org/10.1073/pnas.0705522104

One way to dissect the antibody response to an invading microorganism is to clone the antibody repertoire from immune donors and subsequently characterize the specific antibodies. Recently, methodological advances have allowed investigations of neutr... Read More about Human combinatorial libraries yield rare antibodies that broadly neutralize hepatitis C virus.

Should data monitoring committees assess efficacy when considering safety in trails in acute stroke? (2007)
Journal Article
Bath, P. M., Gray, L. J., & Wahlgren, N. (2007). Should data monitoring committees assess efficacy when considering safety in trails in acute stroke?. International Journal of Clinical Practice, 61(10),

The primary role of a trials Data Monitoring Committee (DMC) is to ensure the safety of enrolled patients. In stroke trials, safety is monitored typically by comparing death and stroke specific events between treatment groups. DMCs may also have the... Read More about Should data monitoring committees assess efficacy when considering safety in trails in acute stroke?.