Skip to main content

Research Repository

Advanced Search

All Outputs (1542)

Nine months of daily LiDAR, orthophotos and MetOcean data from the eroding soft cliff coast at Happisburgh, UK (2024)
Journal Article
Pennington, C., Shaw, M., Brooks, T., Briganti, R., Gómez-Pazo, A., Ruffini, G., Appleton, M., & Payo, A. (2024). Nine months of daily LiDAR, orthophotos and MetOcean data from the eroding soft cliff coast at Happisburgh, UK. Scientific Data, 11, Article 846. https://doi.org/10.1038/s41597-024-03499-3

The dynamic interaction between cliff, beach and shore-platform is key to assessing the sediment balance for coastal erosion risk assessments, but this is poorly understood. We present a dataset containing daily, 3D, colour LiDAR scans of a 450 m coa... Read More about Nine months of daily LiDAR, orthophotos and MetOcean data from the eroding soft cliff coast at Happisburgh, UK.

Association of serum biomarkers with radiographic knee osteoarthritis, knee pain and function in a young, male, trauma-exposed population – findings from the ADVANCE study (2024)
Journal Article
O’Sullivan, O., Stocks, J., Schofield, S., Bilzon, J., Boos, C. J., Bull, A. M. J., Fear, N. T., Watt, F. E., Bennett, A. N., Kluzek, S., & Valdes, A. M. (2024). Association of serum biomarkers with radiographic knee osteoarthritis, knee pain and function in a young, male, trauma-exposed population – findings from the ADVANCE study. Osteoarthritis and Cartilage, https://doi.org/10.1016/j.joca.2024.07.016

Objective The ArmeD SerVices TrAuma RehabilitatioN OutComE (ADVANCE) study is investigating long-term combat-injury outcomes; this sub-study aims to understand the association of osteoarthritis (OA) biomarkers with knee radiographic OA (rOA), pain... Read More about Association of serum biomarkers with radiographic knee osteoarthritis, knee pain and function in a young, male, trauma-exposed population – findings from the ADVANCE study.

High-Efficiency NO conversion via In-Situ grown covalent organic framework on g-C3N4 nanosheets with Single-Atom platinum photocatalyst (2024)
Journal Article
Xiao, Z., Yusuf, A., Ren, Y., Zheng Chen, G., Wang, C., & He, J. (2024). High-Efficiency NO conversion via In-Situ grown covalent organic framework on g-C3N4 nanosheets with Single-Atom platinum photocatalyst. Chemical Engineering Journal, 497, Article 154487. https://doi.org/10.1016/j.cej.2024.154487

This study presents a chemically bonded Pt/TP-BPY-CN/g-C3N4 composite photocatalyst created through an in-situ growth method via Schiff base reaction between g-C3N4 and aldehyde-functionalized TP-BPY-COF. The −H-C-N-H- bonds formed at the g-C3N4 and... Read More about High-Efficiency NO conversion via In-Situ grown covalent organic framework on g-C3N4 nanosheets with Single-Atom platinum photocatalyst.

Optimising kidney and cardiovascular protection in an era of multiple effective treatments (2024)
Journal Article
Taal, M. W. (in press). Optimising kidney and cardiovascular protection in an era of multiple effective treatments. Current Opinion in Nephrology and Hypertension,

Purpose of review: After decades of relying on the control of hypertension and treatment with renin angiotensin system inhibitors as the only evidence-based interventions to slow the progression of chronic kidney disease (CKD), we have entered an er... Read More about Optimising kidney and cardiovascular protection in an era of multiple effective treatments.

Risk factors for long-term cardiovascular post-acute sequelae of COVID-19 infection: A nested case-control study in Hong Kong (2024)
Journal Article
Yu, Q., Fan, M., Lin, C. J., Lui, D. T. W., Tan, K. C. B., Yiu, K. H., Akyea, R. K., Qureshi, N., Lai, F. T. T., Wan, E. Y. F., Li, X., Chan, E. W. Y., Wong, I. C. K., & Chui, C. S. L. (2024). Risk factors for long-term cardiovascular post-acute sequelae of COVID-19 infection: A nested case-control study in Hong Kong. npj Cardiovascular Health, 1(1), Article 10. https://doi.org/10.1038/s44325-024-00011-z

People with COVID-19 can experience post-acute sequelae of SARS-CoV-2 (PASC). Studies on risk factors of PASC outcomes are ongoing, especially for endocrine system-related diseases that may impact the cardiovascular system. Cardiac-related PASC is on... Read More about Risk factors for long-term cardiovascular post-acute sequelae of COVID-19 infection: A nested case-control study in Hong Kong.

How open is the asteroid-mass primordial black hole window? (2024)
Journal Article
Gorton, M., & Green, A. M. (2024). How open is the asteroid-mass primordial black hole window?. SciPost Physics, 17(2), Article 032. https://doi.org/10.21468/SciPostPhys.17.2.032

Primordial black holes (PBHs) can make up all of the dark matter (DM) if their mass, m, is in the so-called “asteroid-mass window”, 10^{17} g ≲ m ≲ 10^{22} g1017g≲m≲1022g. Observational constraints on the abundance of PBHs are usually calculated assu... Read More about How open is the asteroid-mass primordial black hole window?.

Key phosphorylation sites for robust β-arrestin2 binding at the MOR revisited (2024)
Journal Article
Underwood, O., Fritzwanker, S., Glenn, J., Blum, N. K., Batista-Gondin, A., Drube, J., Hoffmann, C., Briddon, S. J., Schulz, S., & Canals, M. (2024). Key phosphorylation sites for robust β-arrestin2 binding at the MOR revisited. Communications Biology, 7, Article 933. https://doi.org/10.1038/s42003-024-06571-1

Desensitisation of the mu-opioid receptor (MOR) is proposed to underlie the initiation of opioid analgesic tolerance and previous work has shown that agonist-induced phosphorylation of the MOR C-tail contributes to this desensitisation. Moreover, pho... Read More about Key phosphorylation sites for robust β-arrestin2 binding at the MOR revisited.

Nonassociative cyclic algebras and the semiassociative Brauer monoid (2024)
Journal Article
Pumplün, S. (2024). Nonassociative cyclic algebras and the semiassociative Brauer monoid. Rendiconti del Circolo Matematico di Palermo, https://doi.org/10.1007/s12215-024-01105-4

We look at classes of semiassociative algebras, with an emphasis on those that canonically generalize associative (generalized) cyclic algebras, and at their behaviour in the semiassociative Brauer monoid defined by Blachar, Haile, Matzri, Rein, an... Read More about Nonassociative cyclic algebras and the semiassociative Brauer monoid.

Comparing physical and chemical properties of soot from laboratory tests and heavy-duty engines used in field operations (2024)
Journal Article
Pacino, A., Rocca, A. L., Smith, J., Berryman, J., Fowell, M., Cairns, A., & Fay, M. W. (2024). Comparing physical and chemical properties of soot from laboratory tests and heavy-duty engines used in field operations. SAE International Journal of Fuels and Lubricants, 18(1), Article 04-18-01-0002

Morphology, nanostructure, and composition of soot extracted from the oil sump of different heavy-duty engines operated under dynamometer and field conditions were investigated. Soot characteristics were then compared to a carbon black sample. Soot w... Read More about Comparing physical and chemical properties of soot from laboratory tests and heavy-duty engines used in field operations.

Is Cadmium Genotoxicity Due to the Induction of Redox Stress and Inflammation? A Systematic Review (2024)
Journal Article
Badawi, K., El Sharazly, B. M., Negm, O., Khan, R., & Carter, W. G. (2024). Is Cadmium Genotoxicity Due to the Induction of Redox Stress and Inflammation? A Systematic Review. Antioxidants, 13(8), Article 932. https://doi.org/10.3390/antiox13080932

The transition metal cadmium (Cd) is toxic to humans and can induce cellular redox stress and inflammation. Cd is a recognized carcinogen, but the molecular mechanisms associated with its genotoxicity and carcinogenicity are not defined. Therefore, a... Read More about Is Cadmium Genotoxicity Due to the Induction of Redox Stress and Inflammation? A Systematic Review.

Unpacking the European Commission: Cabinet Composition and EU Policymaking (2024)
Journal Article
Daniel, W., & Hurka, S. (in press). Unpacking the European Commission: Cabinet Composition and EU Policymaking. Journal of Common Market Studies,

We examine bureaucratic politics within the European Commission, using novel data on the backgrounds of individual members of Commissioners’ cabinets. Although cabinet composition has become increasingly regulated in recent decades, its selection rem... Read More about Unpacking the European Commission: Cabinet Composition and EU Policymaking.

Supramolecular hydrogels enable co-delivery of chemotherapeutics with synergistic efficacy against patient-derived glioblastoma cells and spheroids (2024)
Journal Article
Cavanagh, R. J., Baquain, S., Alexander, C., Scherman, O. A., & Rahman, R. (2024). Supramolecular hydrogels enable co-delivery of chemotherapeutics with synergistic efficacy against patient-derived glioblastoma cells and spheroids. RSC Advances, https://doi.org/10.1039/D4PM00177J

Drug combinations have been shown to be highly effective in many cancer therapies but the ratios of the individual drugs must be adjusted carefully and formulated appropriately to ensure synergistic action. Here we assessed combinations of doxorubici... Read More about Supramolecular hydrogels enable co-delivery of chemotherapeutics with synergistic efficacy against patient-derived glioblastoma cells and spheroids.

Decoding AI in Contemporary Art: A Five-Trope Classification for Understanding and Categorisation (2024)
Journal Article
Salimbeni, G., Benford, S., Reeves, S., & Martindale, S. (2024). Decoding AI in Contemporary Art: A Five-Trope Classification for Understanding and Categorisation. Leonardo, 57(4), 415–421. https://doi.org/10.1162/leon_a_02546

The article presents a historical overview of the classification of contemporary artworks that either have utilized artificial intelligence as a tool in their creation or focus on AI as their central theme or subject matter. The authors analyze artwo... Read More about Decoding AI in Contemporary Art: A Five-Trope Classification for Understanding and Categorisation.

Between animal research and animal welfare: Analysing the openness practices of UK Named Veterinary Surgeons (2024)
Journal Article
McGlacken, R., & Hobson-West, P. (in press). Between animal research and animal welfare: Analysing the openness practices of UK Named Veterinary Surgeons. Animal Welfare Journal,

The use of animals as scientific models is argued to be crucial for producing new scientific and medical knowledge and clinical treatments. However, animal research continues to raise socio-ethical concerns. In recent years, there has been a push for... Read More about Between animal research and animal welfare: Analysing the openness practices of UK Named Veterinary Surgeons.

The limit to evolutionary rescue depends on ploidy in yeast exposed to nystatin (2024)
Journal Article
Ono, J., Kuzmin, A., Miller, L., & Otto, S. P. (2024). The limit to evolutionary rescue depends on ploidy in yeast exposed to nystatin. Canadian Journal of Microbiology, https://doi.org/10.1139/cjm-2023-0235

The number of copies of each chromosome, or ploidy, of an organism is a major genomic factor affecting adaptation. We set out to determine how ploidy can impact the outcome of evolution, as well as the likelihood of evolutionary rescue, using short-t... Read More about The limit to evolutionary rescue depends on ploidy in yeast exposed to nystatin.

Accuracy of glomerular filtration rate estimation using creatinine and cystatin C for identifying and monitoring moderate chronic kidney disease: the eGFR-C study. (2024)
Journal Article
Lamb, E. J., Barratt, J., Brettell, E. A., Cockwell, P., Dalton, R. N., Deeks, J. J., Eaglestone, G., Pellatt-Higgins, T., Kalra, P. A., Khunti, K., Loud, F. C., Ottridge, R. S., Potter, A., Rowe, C., Scandrett, K., Sitch, A. J., Stevens, P. E., Sharpe, C. C., Shinkins, B., Smith, A., …Taal, M. W. (2024). Accuracy of glomerular filtration rate estimation using creatinine and cystatin C for identifying and monitoring moderate chronic kidney disease: the eGFR-C study. Health Technology Assessment, 28(35), 1-169. https://doi.org/10.3310/HYHN1078

Background: Estimation of glomerular filtration rate using equations based on creatinine is widely used to manage chronic kidney disease. In the UK, the Chronic Kidney Disease Epidemiology Collaboration creatinine equation is recommended. Other publi... Read More about Accuracy of glomerular filtration rate estimation using creatinine and cystatin C for identifying and monitoring moderate chronic kidney disease: the eGFR-C study..

Senolytics and Senomorphics Targeting p38MAPK/NF-κB Pathway Protect Endothelial Cells from Oxidative Stress-Mediated Premature Senescence (2024)
Journal Article
Ya, J., & Bayraktutan, U. (2024). Senolytics and Senomorphics Targeting p38MAPK/NF-κB Pathway Protect Endothelial Cells from Oxidative Stress-Mediated Premature Senescence. Cells, 13(15), Article 1292. https://doi.org/10.3390/cells13151292

Oxidative stress is a prominent causal factor in the premature senescence of microvascular endothelial cells and the ensuing blood–brain barrier (BBB) dysfunction. Through the exposure of an in vitro model of human BBB, composed of brain microvascula... Read More about Senolytics and Senomorphics Targeting p38MAPK/NF-κB Pathway Protect Endothelial Cells from Oxidative Stress-Mediated Premature Senescence.

Thin Ga2O3 Layers by Thermal Oxidation of van der Waals GaSe Nanostructures for Ultraviolet Photon Sensing (2024)
Journal Article
Cottam, N. D., Dewes, B. T., Shiffa, M., Cheng, T. S., Novikov, S. V., Mellor, C. J., Makarovsky, O., Gonzalez, D., Ben, T., & Patanè, A. (2024). Thin Ga2O3 Layers by Thermal Oxidation of van der Waals GaSe Nanostructures for Ultraviolet Photon Sensing. ACS Applied Nano Materials, https://doi.org/10.1021/acsanm.4c02685

Two-dimensional semiconductors (2DSEM) based on van der Waals crystals offer important avenues for nanotechnologies beyond the constraints of Moore's law and traditional semiconductors, such as silicon (Si). However, their application necessitates pr... Read More about Thin Ga2O3 Layers by Thermal Oxidation of van der Waals GaSe Nanostructures for Ultraviolet Photon Sensing.