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The experience of apathy in dementia: A qualitative study (2021)
Presentation / Conference Contribution
Baber, W., Chang, C. Y. M., Yates, J., & Dening, T. (2021). The experience of apathy in dementia: A qualitative study. Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 17(57), Article e051411. https://doi.org/10.1002/alz.051411

Background
The presence of apathy is associated with less favourable outcomes in dementia, including more rapid functional and cognitive decline, greater disease severity and increased mortality. We aimed to explore and gain an understanding into ho... Read More about The experience of apathy in dementia: A qualitative study.

Diagnostic utility of artificial intelligence for left ventricular scar identification using cardiac magnetic resonance imaging—A systematic review (2021)
Journal Article
Jathanna, N., Podlasek, A., Sokol, A., Auer, D., Chen, X., & Jamil-Copley, S. (2021). Diagnostic utility of artificial intelligence for left ventricular scar identification using cardiac magnetic resonance imaging—A systematic review. Cardiovascular Digital Health Journal, 2(6), S21-S29. https://doi.org/10.1016/j.cvdhj.2021.11.005

Background: Accurate, rapid quantification of ventricular scar using cardiac magnetic resonance imaging (CMR) carries importance in arrhythmia management and patient prognosis. Artificial intelligence (AI) has been applied to other radiological chall... Read More about Diagnostic utility of artificial intelligence for left ventricular scar identification using cardiac magnetic resonance imaging—A systematic review.

A phase 1/2 study of thiotepa-based immunochemotherapy in relapsed/refractory primary CNS lymphoma: the TIER trial (2021)
Journal Article
Fox, C. P., Ali, A. S., McIlroy, G., Thust, S., Martinez-Calle, N., Jackson, A. E., …Cwynarski, K. (2021). A phase 1/2 study of thiotepa-based immunochemotherapy in relapsed/refractory primary CNS lymphoma: the TIER trial. Blood Advances, 5(20), 4073-4082. https://doi.org/10.1182/bloodadvances.2021004779

Relapsed or refractory primary central nervous system lymphoma (rrPCNSL) confers a poor prognosis with no accepted standard of care. Very few prospective studies have been conducted in this patient group. This study was a multicenter phase 1/2 study... Read More about A phase 1/2 study of thiotepa-based immunochemotherapy in relapsed/refractory primary CNS lymphoma: the TIER trial.

Emotional labour, emotional regulation strategies, and secondary traumatic stress: a cross-sectional study of allied mental health professionals in the UK (2021)
Journal Article
Singh, J., & Hassard, J. (2021). Emotional labour, emotional regulation strategies, and secondary traumatic stress: a cross-sectional study of allied mental health professionals in the UK. Social Science Journal, https://doi.org/10.1080/03623319.2021.1979825

The present study investigates relations among emotional labour, emotional regulation strategies, and secondary traumatic stress (STS) in a sample of allied mental health professionals (AMHPs) in the UK. It empirically examines the relationship betwe... Read More about Emotional labour, emotional regulation strategies, and secondary traumatic stress: a cross-sectional study of allied mental health professionals in the UK.

Increased Placental Cell Senescence and Oxidative Stress in Women with Pre-Eclampsia and Normotensive Post-Term Pregnancies (2021)
Journal Article
Scaife, P. J., Simpson, A., Kurlak, L. O., Briggs, L. V., Gardner, D. S., Pipkin, F. B., …Mistry, H. D. (2021). Increased Placental Cell Senescence and Oxidative Stress in Women with Pre-Eclampsia and Normotensive Post-Term Pregnancies. International Journal of Molecular Sciences, 22(14), Article 7295. https://doi.org/10.3390/ijms22147295

Up to 11% of pregnancies extend to post-term with adverse obstetric events linked to pregnancies over 42 weeks. Oxidative stress and senescence (cells stop growing and dividing by irreversibly arresting their cell cycle and gradually ageing) can resu... Read More about Increased Placental Cell Senescence and Oxidative Stress in Women with Pre-Eclampsia and Normotensive Post-Term Pregnancies.

Patterns of pain killers and other opioid use in patients admitted to a detoxification and dual diagnosis unit, 2016-2019: A retrospective cohort study (2021)
Journal Article
Casado-Espada, N. M., Alvarez-Navares, A., Lozano-Lopez, M. T., Gamonal-Limcaoco, R. S., de la Iglesia-Larrad, J., Garzón, M. Á., …Roncero, C. (2021). Patterns of pain killers and other opioid use in patients admitted to a detoxification and dual diagnosis unit, 2016-2019: A retrospective cohort study. Heroin Addiction And Related Clinical Problems, 23(3), 37-44

Background: Increasing opioid consumption in recent years has given rise to compelling significant concerns. Fentanyl, heroin, new psychoactive substances and prescribed opioids have been named as the main substances involved in the ‘opioid epidemic’... Read More about Patterns of pain killers and other opioid use in patients admitted to a detoxification and dual diagnosis unit, 2016-2019: A retrospective cohort study.

Direct mechanical thrombectomy without intravenous thrombolysis versus bridging therapy for acute ischemic stroke: A meta-analysis of randomized controlled trials (2021)
Journal Article
Podlasek, A., Dhillon, P. S., Butt, W., Grunwald, I. O., & England, T. J. (2021). Direct mechanical thrombectomy without intravenous thrombolysis versus bridging therapy for acute ischemic stroke: A meta-analysis of randomized controlled trials. International Journal of Stroke, 16(6), 621-631. https://doi.org/10.1177/17474930211021353

Background: Direct mechanical thrombectomy may result in similar outcomes compared to a bridging approach with intravenous thrombolysis (IVT + MT) in acute ischemic stroke. Recent randomized controlled trials have varied in their design and noninferi... Read More about Direct mechanical thrombectomy without intravenous thrombolysis versus bridging therapy for acute ischemic stroke: A meta-analysis of randomized controlled trials.

Consensus recommendations for MRI and PET imaging of primary central nervous system lymphoma: guideline statement from the International Primary CNS Lymphoma Collaborative Group (IPCG) (2021)
Journal Article
Barajas, R. F., Politi, L. S., Anzalone, N., Schöder, H., Fox, C. P., Boxerman, J. L., …Hu, L. S. (2021). Consensus recommendations for MRI and PET imaging of primary central nervous system lymphoma: guideline statement from the International Primary CNS Lymphoma Collaborative Group (IPCG). Neuro-Oncology, 23(7), 1056-1071. https://doi.org/10.1093/neuonc/noab020

Advanced molecular and pathophysiologic characterization of primary central nervous system lymphoma (PCNSL) has revealed insights into promising targeted therapeutic approaches. Medical imaging plays a fundamental role in PCNSL diagnosis, staging, an... Read More about Consensus recommendations for MRI and PET imaging of primary central nervous system lymphoma: guideline statement from the International Primary CNS Lymphoma Collaborative Group (IPCG).

Correction to: Optimising medication management in children and young people with ADHD using a computerised test (QbTest): a feasibility randomised controlled trial (2021)
Journal Article
Williams, L., Hall, C. L., Brown, S., Guo, B., James, M., Franceschini, M., …Groom, M. J. (2021). Correction to: Optimising medication management in children and young people with ADHD using a computerised test (QbTest): a feasibility randomised controlled trial. Pilot and Feasibility Studies, 7, Article 94. https://doi.org/10.1186/s40814-021-00830-2

The role of the cingulate cortex in the generation of motor tics and the experience of the premonitory urge-to-tic in Tourette syndrome (2021)
Journal Article
Jackson, S. R., Sigurdsson, H. P., Dyke, K., Condon, M., & Jackson, G. M. (2021). The role of the cingulate cortex in the generation of motor tics and the experience of the premonitory urge-to-tic in Tourette syndrome. Journal of Neuropsychology, 15(3), 340-362. https://doi.org/10.1111/jnp.12242

Tourette syndrome (TS) is a neurological disorder of childhood onset that is characterized by the occurrence of motor and vocal tics. TS is associated with cortical-striatal-thalamic-cortical circuit [CSTC] dysfunction and hyper-excitability of corti... Read More about The role of the cingulate cortex in the generation of motor tics and the experience of the premonitory urge-to-tic in Tourette syndrome.

Auditory beat perception is related to speech output fluency in post-stroke aphasia (2021)
Journal Article
Stefaniak, J. D., Lambon Ralph, M. A., De Dios Perez, B., Griffiths, T. D., & Grube, M. (2021). Auditory beat perception is related to speech output fluency in post-stroke aphasia. Scientific Reports, 11, Article 3168. https://doi.org/10.1038/s41598-021-82809-w

Aphasia affects at least one third of stroke survivors, and there is increasing awareness that more fundamental deficits in auditory processing might contribute to impaired language performance in such individuals. We performed a comprehensive batter... Read More about Auditory beat perception is related to speech output fluency in post-stroke aphasia.

Droplet digital PCR-based detection of circulating tumor DNA from pediatric high grade and diffuse midline glioma patients (2021)
Journal Article
Izquierdo, E., Proszek, P., Pericoli, G., Temelso, S., Clarke, M., Carvalho, D. M., …Jones, C. (2021). Droplet digital PCR-based detection of circulating tumor DNA from pediatric high grade and diffuse midline glioma patients. Neuro-Oncology Advances, 3(1), Article vdab013. https://doi.org/10.1093/noajnl/vdab013

Background
The use of liquid biopsy is of potential high importance for children with high grade (HGG) and diffuse midline gliomas (DMG), particularly where surgical procedures are limited, and invasive biopsy sampling not without risk. To date, how... Read More about Droplet digital PCR-based detection of circulating tumor DNA from pediatric high grade and diffuse midline glioma patients.

Understanding the causes, symptoms and effects of young-onset dementia (2020)
Journal Article
Ray, M., & Dening, T. (2021). Understanding the causes, symptoms and effects of young-onset dementia. Nursing Standard, 36(1), 43-50. https://doi.org/10.7748/ns.2020.e11620

Young-onset dementia refers to dementia that develops before the age of 65 years. It can present with a wide variety of symptoms including cognitive, behavioural, neurological and systemic symptoms, which reflects the wide range of possible causes. Y... Read More about Understanding the causes, symptoms and effects of young-onset dementia.

Investigating the barriers and facilitators to implementing mental health first aid in the workplace: a qualitative study (2020)
Journal Article
Narayanasamy, M. J., THOMSON, L., Coole, C., Nouri, F., & Drummond, A. (2021). Investigating the barriers and facilitators to implementing mental health first aid in the workplace: a qualitative study. Journal of Mental Health Training, Education and Practice, 16(2), 164-178. https://doi.org/10.1108/JMHTEP-12-2019-0064

Purpose: There has been little research into the use and efficacy of Mental Health First Aid across UK workplaces. The present study investigated the implementation of MHFA across six UK organisations, identifying key barriers and facilitators.
Desi... Read More about Investigating the barriers and facilitators to implementing mental health first aid in the workplace: a qualitative study.

Comparing short and long batteries to assess deficits and their neural bases in stroke aphasia (2020)
Preprint / Working Paper
Halai, A. D., De Dios Perez, B., Stefaniak, J. D., & Lambon Ralph, M. A. Comparing short and long batteries to assess deficits and their neural bases in stroke aphasia

Multiple language assessments are necessary for diagnosing, characterising and quantifying the multifaceted deficits observed in many patients’ post-stroke. Current language batteries, however, tend to be an imperfect trade-off between time and sensi... Read More about Comparing short and long batteries to assess deficits and their neural bases in stroke aphasia.

Mild Cognitive Impairment: The Manchester consensus (2020)
Journal Article
Dunne, R. A., Aarsland, D., O'Brien, J. T., Ballard, C., Banerjee, S., Fox, N. C., …Burns, A. (2021). Mild Cognitive Impairment: The Manchester consensus. Age and Ageing, 50(1), 72-80. https://doi.org/10.1093/ageing/afaa228

Given considerable variation in diagnostic and therapeutic practice, there is a need for national guidance on the use of neuroimaging, fluid biomarkers, cognitive testing, follow-up and diagnostic terminology in Mild Cognitive Impairment (MCI). MCI i... Read More about Mild Cognitive Impairment: The Manchester consensus.

Occupational advice to help people return to work following lower limb arthroplasty: the OPAL intervention mapping study (2020)
Journal Article
Baker, P., COOLE, C., DRUMMOND, A., Khan, S., McDaid, C., Hewitt, C., …Rangan, A. (2020). Occupational advice to help people return to work following lower limb arthroplasty: the OPAL intervention mapping study. Health Technology Assessment, 24(45), https://doi.org/10.3310/hta24450

Background
Hip and knee replacements are regularly performed for patients who work. There is little evidence about these patients’ needs and the factors influencing their return to work. There is a paucity of guidance to help patients return to wor... Read More about Occupational advice to help people return to work following lower limb arthroplasty: the OPAL intervention mapping study.