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All Outputs (403)

Regional changes in cerebral perfusion with age when accounting for changes in gray-matter volume (2024)
Journal Article
Hu, J., Craig, M., Knight, S., De Looze, C., Meaney, J., Kenney, R. A., Chen, X., & CHAPPELL, M. (2024). Regional changes in cerebral perfusion with age when accounting for changes in gray-matter volume. Magnetic Resonance in Medicine, https://doi.org/10.1002/mrm.30376

Purpose: One possible contributing factor for cerebral blood flow (CBF) decline in normal aging is the increase in partial volume effects due to brain atrophy, as cortical thinning can exacerbate the contamination of gray-matter (GM) voxels by other... Read More about Regional changes in cerebral perfusion with age when accounting for changes in gray-matter volume.

Online Therapy for Children: Yay or Nay? Clinicians’ Insights from the COVID-19 Era (2024)
Journal Article
Hagyari-Donaldson, P., & Scott, N. (2024). Online Therapy for Children: Yay or Nay? Clinicians’ Insights from the COVID-19 Era. Child and Youth Care Forum, https://doi.org/10.1007/s10566-024-09835-3

Background

The COVID-19 pandemic necessitated an almost overnight shift in mental healthcare from in-person to remote delivery. However, the feasibility of online therapy for children and its potential as a long-term fixture remain underexplored.... Read More about Online Therapy for Children: Yay or Nay? Clinicians’ Insights from the COVID-19 Era.

Lessons from the PROTECT-CH COVID-19 platform trial in care homes (2024)
Journal Article
Bath, P. M., Ball, J., Boyd, M., Gage, H., Glover, M., Godfrey, M., Guthrie, B., Hewitt, J., Howard, R., Jaki, T., Juszczak, E., Lasserson, D., Leighton, P., Leyland, V., Shen Lim, W., Logan, P., Meakin, G., Montgomery, A., Ogollah, R., Passmore, P., …Gordon, A. L. (in press). Lessons from the PROTECT-CH COVID-19 platform trial in care homes. Health Technology Assessment,

Risk of dementia associated with anticholinergic drugs for overactive bladder in adults aged ≥55 years: nested case-control study (2024)
Journal Article
Iyen, B., Coupland, C., Bell, B., Orrell, M., Dening, T., & Avery, T. (2024). Risk of dementia associated with anticholinergic drugs for overactive bladder in adults aged ≥55 years: nested case-control study. BMJ Medicine, 3(1), Article e000799. https://doi.org/10.1136/bmjmed-2023-000799

Objective To investigate whether different anticholinergic drug treatments for overactive bladder have differential risks for incident dementia, in a large representative population of older adults in England.

Design Nested case-control study.... Read More about Risk of dementia associated with anticholinergic drugs for overactive bladder in adults aged ≥55 years: nested case-control study.

Exploring how young people in the UK understand coercive control: a qualitative study (2024)
Journal Article
Sharma, M. E., Paddock, E., & Jones, K. A. (2024). Exploring how young people in the UK understand coercive control: a qualitative study. Journal of Criminal Psychology, https://doi.org/10.1108/JCP-08-2024-0075

Purpose
Since the criminalisation of coercive control (CC), there have been a growing number of cases in the UK; however, there continues to be minimal research, understanding and education about this type of abuse. Hence, it is unsurprising that yo... Read More about Exploring how young people in the UK understand coercive control: a qualitative study.

Commentary: Using QbTest for monitoring pharmacological treatment response in ADHD – are we there yet? (2024)
Journal Article
Bellato, A., Parlatini, V., Groom, M. J., Hall, C. L., Hollis, C., Simonoff, E., Thapar, A., & Cortese, S. (2024). Commentary: Using QbTest for monitoring pharmacological treatment response in ADHD – are we there yet?. Journal of Child Psychology and Psychiatry, https://doi.org/10.1111/jcpp.14071

Individuals with attention-deficit/hyperactivity disorder (ADHD) exhibit varied responses to pharmacological treatments (e.g. stimulants and non-stimulants). Accurately and promptly detecting treatment-related improvements, response failure, or deter... Read More about Commentary: Using QbTest for monitoring pharmacological treatment response in ADHD – are we there yet?.

Healthcare utilisation and costs associated with poor access to diagnosis and treatment for children and young people with tic disorders (2024)
Journal Article
Hall, C. L., Le Novere, M., Murphy, T., McNally, E., Hollis, C., & Hunter, R. (2024). Healthcare utilisation and costs associated with poor access to diagnosis and treatment for children and young people with tic disorders. BMJ Mental Health, 27(1), Article e301241. https://doi.org/10.1136/bmjment-2024-301241

Background: There are no specific national guidelines in England to guide healthcare professionals in how to assess or treat young people with tic disorders. Access to evidence-based treatment, including behavioural therapy is of limited availabilit... Read More about Healthcare utilisation and costs associated with poor access to diagnosis and treatment for children and young people with tic disorders.

Experiences of the COVID-19 pandemic on child and adolescent psychiatric wards: multi-methods investigation (2024)
Journal Article
Holland, J., Da-Silva-Ellimah, M., Roe, J., Morriss, R., & Sayal, K. (2024). Experiences of the COVID-19 pandemic on child and adolescent psychiatric wards: multi-methods investigation. BJPsych Open, 10(6), Article e197. https://doi.org/10.1192/bjo.2024.783

Background
Child and Adolescent Mental Health Services (CAMHS) inpatient beds are unevenly spread throughout England. Where demand outstrips bed availability, young people may be admitted at-distance or to adult psychiatric wards. The COVID-19 pande... Read More about Experiences of the COVID-19 pandemic on child and adolescent psychiatric wards: multi-methods investigation.

Dissociable effects of hyperacusis and misophonia severity imply different mechanisms of decreased sound tolerance (2024)
Journal Article
Smees, R., Simner, J., Hoare, D. J., & Ward, J. (2024). Dissociable effects of hyperacusis and misophonia severity imply different mechanisms of decreased sound tolerance. International Journal of Audiology, https://doi.org/10.1080/14992027.2024.2419558

Objective
It is thought that decreased sound tolerance can be subdivided into distinct types including misophonia (involving specific trigger sounds) and hyperacusis (broader in profile). However, there are few established methods for differentially... Read More about Dissociable effects of hyperacusis and misophonia severity imply different mechanisms of decreased sound tolerance.

Consensus‐Based Guidelines for Communicating a Misdiagnosis of Multiple Sclerosis to Reduce Psychological Distress (2024)
Journal Article
Baufeldt, A. L., Evangelou, N., Moghaddam, N., Gresswell, M., & das Nair, R. (2024). Consensus‐Based Guidelines for Communicating a Misdiagnosis of Multiple Sclerosis to Reduce Psychological Distress. Brain and Behavior, 14(10), Article e70109. https://doi.org/10.1002/brb3.70109

Background
Multiple sclerosis (MS) misdiagnosis is common, and when discovered, frequently leads to substantial disruption to patients’ lives and anxiety for clinicians. Our objective was to develop expert consensus-based guidelines about how to com... Read More about Consensus‐Based Guidelines for Communicating a Misdiagnosis of Multiple Sclerosis to Reduce Psychological Distress.

Humans: an integrative review exploring dehumanisation in advanced dementia (2024)
Journal Article
Bøgmose, J., Olivares Bøgeskov, B. M., Dening, T., & Martinsen, B. (2024). Humans: an integrative review exploring dehumanisation in advanced dementia. Nursing Ethics, https://doi.org/10.1177/09697330241277989

Background: People living with advanced dementia risk being seen as someone without personhood in contemporary societies, an understanding that has been described and challenged for decades in dementia scholarly literature. Such perception can be cha... Read More about Humans: an integrative review exploring dehumanisation in advanced dementia.

Optimal timing of anticoagulation after acute ischaemic stroke with atrial fibrillation (OPTIMAS): a multicentre, blinded-endpoint, phase 4, randomised controlled trial (2024)
Journal Article
Werring, D. J., Dehbi, H. M., Ahmed, N., Arram, L., Best, J. G., Balogun, M., Bennett, K., Bordea, E., Caverly, E., Chau, M., Cohen, H., Cullen, M., Doré, C. J., Engelter, S. T., Fenner, R., Ford, G. A., Gill, A., Hunter, R., James, M., Jayanthi, A., …Freemantle, N. (2024). Optimal timing of anticoagulation after acute ischaemic stroke with atrial fibrillation (OPTIMAS): a multicentre, blinded-endpoint, phase 4, randomised controlled trial. Lancet, 404(10464), 1731-1741. https://doi.org/10.1016/S0140-6736%2824%2902197-4

Background: The optimal timing of anticoagulation for patients with acute ischaemic stoke with atrial fibrillation is uncertain. We investigated the efficacy and safety of early compared with delayed initiation of direct oral anticoagulants (DOACs) i... Read More about Optimal timing of anticoagulation after acute ischaemic stroke with atrial fibrillation (OPTIMAS): a multicentre, blinded-endpoint, phase 4, randomised controlled trial.

Effectiveness and cost-effectiveness of online recorded recovery narratives in improving quality of life for people with psychosis experience (NEON Trial): a pragmatic randomised controlled trial (2024)
Journal Article
Slade, M., Rennick-Egglestone, S., Robinson, C., Newby, C., Elliott, R. A., Ali, Y., Yeo, C., Glover, T., Gavan, S. P., Paterson, L., Pollock, K., Priebe, S., Thornicroft, G., Keppens, J., Smuk, M., Franklin, D., Walcott, R., Harrison, J., Robotham, D., Bradstreet, S., …Ng, F. (2024). Effectiveness and cost-effectiveness of online recorded recovery narratives in improving quality of life for people with psychosis experience (NEON Trial): a pragmatic randomised controlled trial. Lancet Regional Health – Europe, 47(47), Article 101101. https://doi.org/10.1016/j.lanepe.2024.101101

Background
The Narrative Experiences Online (NEON) Intervention provides self-managed web-based access to mental health recovery narratives (n = 659). We evaluated effectiveness and cost-effectiveness in improving quality of life for adults resident... Read More about Effectiveness and cost-effectiveness of online recorded recovery narratives in improving quality of life for people with psychosis experience (NEON Trial): a pragmatic randomised controlled trial.

EXPRESS: Memory for health information: Influences of age, hearing aids, and multisensory presentation (2024)
Journal Article
Stacey, J., Atkin, C., Roberts, K. L., Henshaw, H., ALLEN, H., & Badham, S. P. (2024). EXPRESS: Memory for health information: Influences of age, hearing aids, and multisensory presentation. Quarterly Journal of Experimental Psychology, https://doi.org/10.1177/17470218241295722

Background. We investigated how presenting online health information in different modalities can influence memory, as this may be particularly important for older adults who may need to make regular decisions about health, and could also face additio... Read More about EXPRESS: Memory for health information: Influences of age, hearing aids, and multisensory presentation.

Implementing vocational rehabilitation for people with multiple sclerosis in the UK National Health Service: a mixed-methods feasibility study (2024)
Journal Article
De Dios Perez, B., Holmes, J., Elder, T., Lindley, R., Evangelou, N., das Nair, R., Senior, C., Booth, V., Hassard, J., Ford, H. L., Newsome, I., & Radford, K. (2024). Implementing vocational rehabilitation for people with multiple sclerosis in the UK National Health Service: a mixed-methods feasibility study. Disability and Rehabilitation, https://doi.org/10.1080/09638288.2024.2417031

Purpose: To implement a job retention vocational rehabilitation (VR) intervention (MSVR) for people with multiple sclerosis (MS) and their employers in the UK National Health Service (NHS). Methods: Multicentre, single-arm feasibility study with post... Read More about Implementing vocational rehabilitation for people with multiple sclerosis in the UK National Health Service: a mixed-methods feasibility study.

The clinical and cost effectiveness of a STAndardised DIagnostic Assessment for children and adolescents with emotional difficulties (STADIA); multi- centre randomised controlled trial (2024)
Journal Article
Sayal, K., Wyatt, L., Partlett, C., Ewart, C., Bhardwaj, A., Dubicka, B., Marshall, T., Gledhill, J., Lang, A., Sprange, K., Thomson, L., Moody, S., Holt, G., Bould, H., Upton, C., Keane, M., Cox, E., James, M., & Montgomery, A. (in press). The clinical and cost effectiveness of a STAndardised DIagnostic Assessment for children and adolescents with emotional difficulties (STADIA); multi- centre randomised controlled trial. Journal of Child Psychology and Psychiatry,

Pre‐hospital transdermal glyceryl trinitrate for transient ischaemic attack: Data from the RIGHT‐2 trial (2024)
Journal Article
Appleton, J. P., Dixon, M., Woodhouse, L. J., Anderson, C. S., Ankolekar, S., Cala, L., England, T. J., Godolphin, P. J., Krishnan, K., Mair, G., Muir, K. W., Potter, J., Price, C. I., Randall, M., Robinson, T. G., Roffe, C., Rothwell, P. M., Sandset, E. C., Saver, J. L., Siriwardena, A. N., …Bath, P. M. (2024). Pre‐hospital transdermal glyceryl trinitrate for transient ischaemic attack: Data from the RIGHT‐2 trial. European Journal of Neurology, 31(12), Article e16502. https://doi.org/10.1111/ene.16502

Background and purpose
Ambulance trials assessing interventions in suspected stroke patients will recruit patients with currently active symptoms that will resolve into transient ischaemic attack (TIA). The safety and efficacy of glyceryl trinitrate... Read More about Pre‐hospital transdermal glyceryl trinitrate for transient ischaemic attack: Data from the RIGHT‐2 trial.

Perception and acquaintance of stroke specialists on non-inferiority trials: An international survey (2024)
Journal Article
Katsanos, A. H., Lioutas, V.-A., Yperzeele, L., Ullberg, T., Li, L., Ramage, E. R., Koltsov, I. A., Shapranova, J., Howard, G., Bath, P. M., & Khan, M. (2025). Perception and acquaintance of stroke specialists on non-inferiority trials: An international survey. Journal of Stroke and Cerebrovascular Diseases, 34(1), Article 108132. https://doi.org/10.1016/j.jstrokecerebrovasdis.2024.108132

Introduction
The adoption of non-inferiority trial designs for assessing new interventions in stroke treatment is on the rise. We designed a survey to assess stroke specialists' understanding and familiarity with non-inferiority trials and margins.... Read More about Perception and acquaintance of stroke specialists on non-inferiority trials: An international survey.

Myocardial Scar Imaging: Viability Beyond REVIVED (2024)
Journal Article
Kiberu, Y., Jathanna, N., Narayanan, N., Vanezis, A. P., Erhayiem, B., Graham, A., & Jamil-Copley, S. (2024). Myocardial Scar Imaging: Viability Beyond REVIVED. Current Cardiovascular Imaging Reports, 17, 107–114. https://doi.org/10.1007/s12410-024-09597-5

Purpose of Review: It was previously believed that the presence of myocardial viability in patients with significant coronary artery disease improved outcomes following revascularisation, but the landmark STITCH trial found no significant correlation... Read More about Myocardial Scar Imaging: Viability Beyond REVIVED.