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All Outputs (393)

Optimal timing of anticoagulation after acute ischaemic stroke with atrial fibrillation (OPTIMAS): a multicentre, blinded-endpoint, phase 4, randomised controlled trial (2024)
Journal Article
Werring, D. J., Dehbi, H.-M., Ahmed, N., Arram, L., Best, J. G., Balogun, M., Bennett, K., Bordea, E., Caverly, E., Chau, M., Cohen, H., Cullen, M., Doré, C. J., Engelter, S. T., Fenner, R., Ford, G. A., Gill, A., Hunter, R., James, M., Jayanthi, A., …Freemantle, N. (2024). Optimal timing of anticoagulation after acute ischaemic stroke with atrial fibrillation (OPTIMAS): a multicentre, blinded-endpoint, phase 4, randomised controlled trial. Lancet, https://doi.org/10.1016/S0140-6736%2824%2902197-4

Background
The optimal timing of anticoagulation for patients with acute ischaemic stoke with atrial fibrillation is uncertain. We investigated the efficacy and safety of early compared with delayed initiation of direct oral anticoagulants (DOACs)... Read More about Optimal timing of anticoagulation after acute ischaemic stroke with atrial fibrillation (OPTIMAS): a multicentre, blinded-endpoint, phase 4, randomised controlled trial.

Effectiveness and cost-effectiveness of online recorded recovery narratives in improving quality of life for people with psychosis experience (NEON Trial): a pragmatic randomised controlled trial (2024)
Journal Article
Slade, M., Rennick-Egglestone, S., Robinson, C., Newby, C., Elliott, R. A., Ali, Y., Yeo, C., Glover, T., Gavan, S. P., Paterson, L., Pollock, K., Priebe, S., Thornicroft, G., Keppens, J., Smuk, M., Franklin, D., Walcott, R., Harrison, J., Robotham, D., Bradstreet, S., …Ng, F. (2024). Effectiveness and cost-effectiveness of online recorded recovery narratives in improving quality of life for people with psychosis experience (NEON Trial): a pragmatic randomised controlled trial. Lancet Regional Health – Europe, 2024(47), Article 101101. https://doi.org/10.1016/j.lanepe.2024.101101

Background
The Narrative Experiences Online (NEON) Intervention provides self-managed web-based access to mental health recovery narratives (n = 659). We evaluated effectiveness and cost-effectiveness in improving quality of life for adults resident... Read More about Effectiveness and cost-effectiveness of online recorded recovery narratives in improving quality of life for people with psychosis experience (NEON Trial): a pragmatic randomised controlled trial.

The clinical and cost effectiveness of a STAndardised DIagnostic Assessment for children and adolescents with emotional difficulties (STADIA); multi- centre randomised controlled trial (2024)
Journal Article
Sayal, K., Wyatt, L., Partlett, C., Ewart, C., Bhardwaj, A., Dubicka, B., Marshall, T., Gledhill, J., Lang, A., Sprange, K., Thomson, L., Moody, S., Holt, G., Bould, H., Upton, C., Keane, M., Cox, E., James, M., & Montgomery, A. (in press). The clinical and cost effectiveness of a STAndardised DIagnostic Assessment for children and adolescents with emotional difficulties (STADIA); multi- centre randomised controlled trial. Journal of Child Psychology and Psychiatry,

Implementing vocational rehabilitation for people with multiple sclerosis in the UK National Health Service: a mixed-methods feasibility study (2024)
Journal Article
De Dios Perez, B., Holmes, J., Elder, T., Lindley, R., Evangelou, N., Das Nair, R., Senior, C., Booth, V., Hassard, J., Ford, H. L., Newsome, I., & Radford, K. (2024). Implementing vocational rehabilitation for people with multiple sclerosis in the UK National Health Service: a mixed-methods feasibility study. Disability and Rehabilitation, https://doi.org/10.1080/09638288.2024.2417031

Purpose
To implement a job retention vocational rehabilitation (VR) intervention (MSVR) for people with multiple sclerosis (MS) and their employers in the UK National Health Service (NHS).

Methods
Multicentre, single-arm feasibility study with p... Read More about Implementing vocational rehabilitation for people with multiple sclerosis in the UK National Health Service: a mixed-methods feasibility study.

Memory for health information: Influences of age, hearing aids, and multisensory presentation (2024)
Journal Article
Henshaw, H., Stacey, J., Badham, S., Roberts, K., Atkin, C., & Allen, H. (online). Memory for health information: Influences of age, hearing aids, and multisensory presentation. Quarterly Journal of Experimental Psychology, https://doi.org/10.1177/17470218241295722

Background. We investigated how presenting online health information in different modalities can influence memory, as this may be particularly important for older adults who may need to make regular decisions about health, and could also face additio... Read More about Memory for health information: Influences of age, hearing aids, and multisensory presentation.

Using QbTest for monitoring pharmacological treatment response in ADHD: are we there yet? (2024)
Journal Article
Bellato, A., Parlatini, V., Groom, M. J., Hall, C. L., Hollis, C., Simonoff, E., Thapar, A., & Cortese, S. (in press). Using QbTest for monitoring pharmacological treatment response in ADHD: are we there yet?. Journal of Child Psychology and Psychiatry,

Individuals with Attention-Deficit/Hyperactivity Disorder (ADHD) exhibit varied responses to pharmacological treatments (e.g., stimulants and non-stimulants). Accurately and promptly detecting treatment-related improvements, response failure, or dete... Read More about Using QbTest for monitoring pharmacological treatment response in ADHD: are we there yet?.

Comparison of Echo Planar and Turbo Spin Echo Diffusion‐Weighted Imaging in Intraoperative MRI (2024)
Journal Article
Thorpe, J. C., Thust, S. C., Gillon, C. H., Rowe, S., Swain, C. E., MacArthur, D. C., Howarth, S. P., Avula, S., Morgan, P. S., & Dineen, R. A. (2024). Comparison of Echo Planar and Turbo Spin Echo Diffusion‐Weighted Imaging in Intraoperative MRI. Journal of Magnetic Resonance Imaging, https://doi.org/10.1002/jmri.29614

Background: Diffusion-weighted imaging (DWI) is routinely used in brain tumor surgery guided by intraoperative MRI (IoMRI). However, conventional echo planar imaging DWI (EPI-DWI) is susceptible to distortion and artifacts that affect image quality.... Read More about Comparison of Echo Planar and Turbo Spin Echo Diffusion‐Weighted Imaging in Intraoperative MRI.

A national evaluation of QbTest to support ADHD assessment: a real-world, mixed methods approach (2024)
Journal Article
Hall, S. S., McKenzie, C., Thomson, L., Ingall, B.-R., Groom, M. J., McGlennon, N., Dines-Allen, M., & Hall, C. L. (2024). A national evaluation of QbTest to support ADHD assessment: a real-world, mixed methods approach. BMC Health Services Research, 24, Article 1201 . https://doi.org/10.1186/s12913-024-11693-7

Background
QbTest is a commercially available, computerised test of attention, impulsivity, and activity designed to assist with the diagnosis of attention deficit hyperactivity disorder (ADHD). Health Innovation East Midlands (formerly East Midland... Read More about A national evaluation of QbTest to support ADHD assessment: a real-world, mixed methods approach.

Synthetic cerebral blood vessel generator for training anatomically plausible deep learning models (2024)
Presentation / Conference Contribution
Kenyon, G., Lau, S., Perperidis, A., CHAPPELL, M., & Jenkinson, M. (2024, July). Synthetic cerebral blood vessel generator for training anatomically plausible deep learning models. Presented at MIUA - Medical Image Understanding and Analysis - 2024, Manchester

Blood vessel networks, with their complex geometrical and topological characteristics, play a significant role in diagnosing and understanding various cerebrovascular diseases. Deep learning (DL) segmentation methods can aid in analysing these struct... Read More about Synthetic cerebral blood vessel generator for training anatomically plausible deep learning models.

Organizations offering line manager training in mental health and presenteeism: A secondary data analysis of organizational-level data (2024)
Journal Article
Dulal-Arthur, T., Hassard, J., Bourke, J., Wishart, M., Bartle, C., Roper, S., Belt, V., Leka, S., Pahl, N., Thomson, L., & Blake, H. (2024). Organizations offering line manager training in mental health and presenteeism: A secondary data analysis of organizational-level data. Journal of Occupational and Organizational Psychology, https://doi.org/10.1111/joop.12552

Presenteeism (working while ill) due to mental ill-health is estimated to be one of the largest economic costs to employers. We seek to investigate the relationship between line manager training in mental health (MH) and presenteeism trends at work.... Read More about Organizations offering line manager training in mental health and presenteeism: A secondary data analysis of organizational-level data.

Organizations offering line manager training in mental health and presenteeism: A secondary data analysis of organizational‐level data (2024)
Journal Article
Dulal‐Arthur, T., Hassard, J., Bourke, J., Wishart, M., Bartle, C., Roper, S., Belt, V., Leka, S., Pahl, N., Thomson, L., & Blake, H. (2024). Organizations offering line manager training in mental health and presenteeism: A secondary data analysis of organizational‐level data. Journal of Occupational and Organizational Psychology, https://doi.org/10.1111/joop.12552

Presenteeism (working while ill) due to mental ill‐health is estimated to be one of the largest economic costs to employers. We seek to investigate the relationship between line manager training in mental health (MH) and presenteeism trends at work.... Read More about Organizations offering line manager training in mental health and presenteeism: A secondary data analysis of organizational‐level data.

Development of a Vocational Rehabilitation Intervention to support Return to Work and Wellbeing following Major Trauma: A Person-Based Approach (2024)
Journal Article
Radford, K., Kettlewell, J., das Nair, R., Morriss, R., Holmes, J., Kellezi, B., Timmons, S., Jones, T., Tressider, H., Andrews, I., Bridger, K., Patel, P., Lindley, R., De Dios Perez, B., Statham, A., Jones, T., Hoffman, K., James, M., Kendrick, D., & ROWTATE study team. (2024). Development of a Vocational Rehabilitation Intervention to support Return to Work and Wellbeing following Major Trauma: A Person-Based Approach. BMJ Open, 14(10), Article e085724. https://doi.org/10.1136/bmjopen-2024-085724+

Objectives: Major trauma centres save lives but rehabilitation to support return-to-work (RTW) is lacking. This paper describes development of a vocational rehabilitation intervention (the ROWTATE intervention) to support RTW following traumatic inju... Read More about Development of a Vocational Rehabilitation Intervention to support Return to Work and Wellbeing following Major Trauma: A Person-Based Approach.

What do employers need when supporting stroke survivors to return to work?: a mixed-methods study (2024)
Journal Article
Craven, K., Kettlewell, J., De Dios Péreza, B., Powers, K., Holmes, J., & Radford, K. A. (2024). What do employers need when supporting stroke survivors to return to work?: a mixed-methods study. Topics in Stroke Rehabilitation, https://doi.org/10.1080/10749357.2024.2409005

Background

Employers are key in supporting stroke survivors to return to work (RTW) but do not always have knowledge/skills or guidance to do so.

Objectives

To explore employers’ needs for provision of post-stroke RTW support.

Methods... Read More about What do employers need when supporting stroke survivors to return to work?: a mixed-methods study.

Dynamic Interplay of Online Risk and Resilience in Adolescence (DIORA): a protocol for a 12-month prospective observational study testing the associations among digital activity, affective and cognitive reactions and depression symptoms in a community sample of UK adolescents (2024)
Journal Article
Kostyrka-Allchorne, K., Stoilova, M., Bourgaize, J., Murray, A., Azeri, E., Hollis, C., Townsend, E., Livingstone, S., & Sonuga-Barke, E. (2024). Dynamic Interplay of Online Risk and Resilience in Adolescence (DIORA): a protocol for a 12-month prospective observational study testing the associations among digital activity, affective and cognitive reactions and depression symptoms in a community sample of UK adolescents. BMJ Open, 14(9), Article e085061. https://doi.org/10.1136/bmjopen-2024-085061

Introduction The impact of digital activity on adolescent mental health has been difficult to assess because of methodological limitations and a lack of strong theory. Dynamic Interplay of Online Risk and Resilience in Adolescence (DIORA) is a longit... Read More about Dynamic Interplay of Online Risk and Resilience in Adolescence (DIORA): a protocol for a 12-month prospective observational study testing the associations among digital activity, affective and cognitive reactions and depression symptoms in a community sample of UK adolescents.

Providing emotional support during the process of multiple sclerosis diagnosis (PrEliMS): A feasibility randomised controlled trial (2024)
Journal Article
Das Nair, R., Mhizha-Murira, J. R., Topcu, G., Tindall, T., Bale, C., Moghaddam, N., Scheffler-Ansari, G., Drummond, A., Fitzsimmons, D., & Evangelou, N. (2024). Providing emotional support during the process of multiple sclerosis diagnosis (PrEliMS): A feasibility randomised controlled trial. Clinical Rehabilitation, https://doi.org/10.1177/02692155241284781

Objectives
To evaluate the feasibility and acceptability of an emotional support programme for newly diagnosed people with multiple sclerosis.

Design
Three-arm, mixed methods, randomised controlled trial comparing usual care, versus usual care p... Read More about Providing emotional support during the process of multiple sclerosis diagnosis (PrEliMS): A feasibility randomised controlled trial.

Healthcare utilisation and costs associated with poor access to diagnosis and treatment for children and young people with tic disorders (2024)
Journal Article
Hall, C. L., Le Novere, M., Murphy, T., McNally, E., Hollis, C., & Hunter, R. (in press). Healthcare utilisation and costs associated with poor access to diagnosis and treatment for children and young people with tic disorders. BMJ Mental Health,

Background: There are no specific national guidelines in England to guide healthcare professionals in how to assess or treat young people with tic disorders. Access to evidence-based treatment, including behavioural therapy is of limited availabilit... Read More about Healthcare utilisation and costs associated with poor access to diagnosis and treatment for children and young people with tic disorders.

A qualitative study of the views of ethnic minority healthcare workers towards COVID-19 Vaccine Education (CoVE) to support vaccine promotion and uptake (2024)
Journal Article
Blake, H., Premakumar, V., Premakumar, A., Fecowycz, A., Khulumula, S. K., Jones, W., & Somerset, S. (2024). A qualitative study of the views of ethnic minority healthcare workers towards COVID-19 Vaccine Education (CoVE) to support vaccine promotion and uptake. New Solutions: A Journal of Environmental and Occupational Health Policy, 34(3), 198-212. https://doi.org/10.1177/1048291124127391

Ethnic minority healthcare workers (EMHCW) are at high risk of COVID-19 infection and adverse health outcomes, but vaccine uptake is low among ethnic minority communities, including EMHCW. We explored the views of EMHCW towards COVID-19 Vaccine Educa... Read More about A qualitative study of the views of ethnic minority healthcare workers towards COVID-19 Vaccine Education (CoVE) to support vaccine promotion and uptake.

Occupational support following arthroplasty of the lower limb (OPAL): trial protocol for a UK-wide phase III randomised controlled trial (2024)
Journal Article
Sheehan, L., Woodward, A., Adamson, J., Archer, M., Drummond, A., Hewison, A., Jordan, C., Keding, A., Kottam, L., Madan, I., Martland, M., McDaid, C., McDonald, D. A., Parkinson, G., Reed, M., Sinclair, L., Smith, T. O., Thomson, L., Watkins, L., Wu, Q., & Baker, P. (2024). Occupational support following arthroplasty of the lower limb (OPAL): trial protocol for a UK-wide phase III randomised controlled trial. BMJ Open, 14(9), Article e085962. https://doi.org/10.1136/bmjopen-2024-085962

Background: In the UK, one in four patients are in work at the time of their hip or knee replacement surgery. These patients receive little support about their return to work (RTW). There is a need for an occupational support intervention that encour... Read More about Occupational support following arthroplasty of the lower limb (OPAL): trial protocol for a UK-wide phase III randomised controlled trial.