All Outputs (332)

Development of the impact of tinnitus in children questionnaire (iTICQ) (2024)
Journal Article
Smith, H., Fackrell, K., Kennedy, V., Barry, J. G., Benton, C., Partridge, L., & Hoare, D. J. (2024). Development of the impact of tinnitus in children questionnaire (iTICQ). Frontiers in Audiology and Otology, 1, Article 1323864. https://doi.org/10.3389/fauot.2023.1323864

Introduction: Tinnitus is a common disorder of the auditory system. Questionnaires are essential tools for clinical assessment and research. Whilst many questionnaires are available to measure different aspects of tinnitus complaint in adults, there... Read More about Development of the impact of tinnitus in children questionnaire (iTICQ).

Enhancing emotion regulation with an in situ socially assistive robot among LGBTQ+ youth with self-harm ideation: protocol for a randomised controlled trial (2024)
Journal Article
Williams, A. J., Cleare, S., Borschmann, R., Tench, C. R., Gross, J., Hollis, C., …Slovak, P. (2024). Enhancing emotion regulation with an in situ socially assistive robot among LGBTQ+ youth with self-harm ideation: protocol for a randomised controlled trial. BMJ Open, 14(1), Article e079801. https://doi.org/10.1136/bmjopen-2023-079801

Introduction: Purrble, a socially assistive robot, was codesigned with children to support in situ emotion regulation. Preliminary evidence has found that LGBTQ+ youth are receptive to Purrble and find it to be an acceptable intervention to assist wi... Read More about Enhancing emotion regulation with an in situ socially assistive robot among LGBTQ+ youth with self-harm ideation: protocol for a randomised controlled trial.

Supporting employers and their employees with mental hEalth conditions to remain eNgaged and producTive at wORk (MENTOR): A feasibility randomised controlled trial (2024)
Journal Article
Prudenzi, A., Gill, K., MacArthur, M., Hastings, O., Moukhtarian, T., Jadhakhan, F., …Marwaha, S. (2024). Supporting employers and their employees with mental hEalth conditions to remain eNgaged and producTive at wORk (MENTOR): A feasibility randomised controlled trial. Journal of Contextual Behavioral Science, 31, Article 100720. https://doi.org/10.1016/j.jcbs.2023.100720

Employees with mental health conditions often struggle to remain in employment. During the COVID-19 pandemic, these employees faced additional stressors, including worsening mental health and work productivity. In 2020, as part of a larger programme... Read More about Supporting employers and their employees with mental hEalth conditions to remain eNgaged and producTive at wORk (MENTOR): A feasibility randomised controlled trial.

The Role of Stem Cells as Therapeutics for Ischaemic Stroke (2024)
Journal Article
Ya, J., Pellumbaj, J., Hashmat, A., & Bayraktutan, U. (2024). The Role of Stem Cells as Therapeutics for Ischaemic Stroke. Cells, 13(2), Article 112. https://doi.org/10.3390/cells13020112

Stroke remains one of the leading causes of death and disability worldwide. Current reperfusion treatments for ischaemic stroke are limited due to their narrow therapeutic window in rescuing ischaemic penumbra. Stem cell therapy offers a promising al... Read More about The Role of Stem Cells as Therapeutics for Ischaemic Stroke.

Dual Antiplatelet Treatment up to 72 Hours after Ischemic Stroke (2023)
Journal Article
Gao, Y., Chen, W., Pan, Y., Jing, J., Wang, C., Johnston, S. C., …Wang, Y. (2023). Dual Antiplatelet Treatment up to 72 Hours after Ischemic Stroke. New England Journal of Medicine, 389(26), 2413-2424. https://doi.org/10.1056/nejmoa2309137

BACKGROUND: Dual antiplatelet treatment has been shown to lower the risk of recurrent stroke as compared with aspirin alone when treatment is initiated early (≤24 hours) after an acute mild stroke. The effect of clopidogrel plus aspirin as compared w... Read More about Dual Antiplatelet Treatment up to 72 Hours after Ischemic Stroke.

Denoising Diffusion MRI: Considerations and implications for analysis (2023)
Journal Article
Manzano-Patron, J.-P., Moeller, S., Andersson, J. L. R., Ugurbil, K., Yacoub, E., & Sotiropoulos, S. N. (2024). Denoising Diffusion MRI: Considerations and implications for analysis. Imaging Neuroscience, 2, 1-29. https://doi.org/10.1101/2023.07.24.550348

Development of diffusion MRI (dMRI) denoising approaches has experienced considerable growth over the last years. As noise can inherently reduce accuracy and precision in measurements, its effects have been well characterised both in terms of uncerta... Read More about Denoising Diffusion MRI: Considerations and implications for analysis.

"Far Away from Home": Adolescent inpatient admissions far from home, out- of-area or to adult wards: A national surveillance study.) in collaboration with the CAPSS Scientific Committee (2023)
Journal Article
Holland, J., Dubicka, B., Ford, T., & Wagner, A. (2023). "Far Away from Home": Adolescent inpatient admissions far from home, out- of-area or to adult wards: A national surveillance study.) in collaboration with the CAPSS Scientific Committee. BMJ Mental Health, 26(1), Article e300843. https://doi.org/10.1136/bmjment-2023-300843

Background: The increasing prevalence and acuity of mental disorders among children and adolescents have placed pressure on services, including inpatient care, and resulted in young people being admitted at-distance or to adult wards. Little empirica... Read More about "Far Away from Home": Adolescent inpatient admissions far from home, out- of-area or to adult wards: A national surveillance study.) in collaboration with the CAPSS Scientific Committee.

Analysis of endothelial progenitor cell subtypes as clinical biomarkers for elderly patients with ischaemic stroke (2023)
Journal Article
Kadir, R. R. A., Rakkar, K., Othman, O. A., Sprigg, N., Bath, P. M., & Bayraktutan, U. (2023). Analysis of endothelial progenitor cell subtypes as clinical biomarkers for elderly patients with ischaemic stroke. Scientific Reports, 13(1), Article 21843. https://doi.org/10.1038/s41598-023-48907-7

Endothelial progenitor cells (EPCs), expressing markers for stemness (CD34), immaturity (CD133) and endothelial maturity (KDR), may determine the extent of post-stroke vascular repair. Given the prevalence of stroke in elderly, this study explored wh... Read More about Analysis of endothelial progenitor cell subtypes as clinical biomarkers for elderly patients with ischaemic stroke.

Analysis of Endothelial Progenitor Cell Subtypes as Clinical Biomarkers for Elderly Patients with Ischaemic Stroke (2023)
Journal Article
ABDULKADIR, R., RAKKAR, K., OTHMAN, O., SPRIGG, N., BATH, P., & BAYRAKTUTAN, U. (2023). Analysis of Endothelial Progenitor Cell Subtypes as Clinical Biomarkers for Elderly Patients with Ischaemic Stroke. Scientific Reports, 13, Article 21843. https://doi.org/10.1038/s41598-023-48907-7

Endothelial progenitor cells (EPCs), expressing markers for stemness (CD34), immaturity (CD133) and endothelial maturity (KDR), may determine the extent of post-stroke vascular repair. Given the prevalence of stroke in elderly, this study explored wh... Read More about Analysis of Endothelial Progenitor Cell Subtypes as Clinical Biomarkers for Elderly Patients with Ischaemic Stroke.

Pet ownership and grief - Exploring how pet ownership effects owners' mental wellbeing during times of grief, a qualitative pilot study (2023)
Journal Article
French, B., Anctil, Z., Brown, B., & Hall, S. (2023). Pet ownership and grief - Exploring how pet ownership effects owners' mental wellbeing during times of grief, a qualitative pilot study. Pet Behaviour Science, 15, 1-19

Animal-assisted interventions (AAIs) have exhibited encouraging outcomes in enhancing human mental health. However, research has investigated the potential benefits of untrained pets for human mental wellbeing, as training animals for AAI can be cost... Read More about Pet ownership and grief - Exploring how pet ownership effects owners' mental wellbeing during times of grief, a qualitative pilot study.

Developing a list of core competencies for medical aspects of healthcare delivery in care homes: scoping review and Delphi process (2023)
Journal Article
McCarthy, L., Borley, K., Ancelin, T., Carroll, R., Chadborn, N., Blundell, A. G., & Gordon, A. L. (2023). Developing a list of core competencies for medical aspects of healthcare delivery in care homes: scoping review and Delphi process. Age and Ageing, 52(12), Article afad237. https://doi.org/10.1093/ageing/afad237

Background Care Home residents live with frailty and multiple long-term conditions. Their medical management is complex and specialised. We set out to develop a list of core competencies for doctors providing medical care in long-term care homes. M... Read More about Developing a list of core competencies for medical aspects of healthcare delivery in care homes: scoping review and Delphi process.

Prevention of infections and fever to improve outcome in older patients with acute stroke (PRECIOUS): a randomised, open, phase III, multifactorial, clinical trial with blinded outcome assessment (2023)
Journal Article
de Jonge, J. C., Sluis, W. M., Reinink, H., Bath, P. M., Woodhouse, L. J., Zweedijk, B., …van der Worp, H. B. (2024). Prevention of infections and fever to improve outcome in older patients with acute stroke (PRECIOUS): a randomised, open, phase III, multifactorial, clinical trial with blinded outcome assessment. Lancet Regional Health – Europe, 36, Article 100782. https://doi.org/10.1016/j.lanepe.2023.100782

Background Infections and fever after stroke are associated with poor functional outcome or death. We assessed whether prophylactic treatment with anti-emetic, antibiotic, or antipyretic medication would improve functional outcome in older patient... Read More about Prevention of infections and fever to improve outcome in older patients with acute stroke (PRECIOUS): a randomised, open, phase III, multifactorial, clinical trial with blinded outcome assessment.

Challenges and Experiences in Multicenter Prehospital Stroke Research: Narrative Data from the Rapid Intervention with Glyceryl Trinitrate in Hypertensive Stroke Trial-2 (RIGHT-2) (2023)
Journal Article
Dixon, M., Williams, J., Bath, P. M., Investigators, R., & for the RIGHT-2 Investigators. (2023). Challenges and Experiences in Multicenter Prehospital Stroke Research: Narrative Data from the Rapid Intervention with Glyceryl Trinitrate in Hypertensive Stroke Trial-2 (RIGHT-2). Prehospital Emergency Care, https://doi.org/10.1080/10903127.2023.2287171

Background: Ambulance services are increasingly research active and the Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2) is the largest United Kingdom (UK) ambulance-based randomized controlled trial in stroke. We... Read More about Challenges and Experiences in Multicenter Prehospital Stroke Research: Narrative Data from the Rapid Intervention with Glyceryl Trinitrate in Hypertensive Stroke Trial-2 (RIGHT-2).

Evaluating artificial intelligence software for delineating hemorrhage extent on CT brain imaging in stroke: AI delineation of ICH on CT. (2023)
Journal Article
Vacek, A., Mair, G., White, P., Bath, P. M., Muir, K. W., Al-Shahi Salman, R., …Wardlaw, J. M. (2024). Evaluating artificial intelligence software for delineating hemorrhage extent on CT brain imaging in stroke: AI delineation of ICH on CT. Journal of Stroke and Cerebrovascular Diseases, 33(1), Article 107512. https://doi.org/10.1016/j.jstrokecerebrovasdis.2023.107512

Background: : The extent and distribution of intracranial hemorrhage (ICH) directly affects clinical management. Artificial intelligence (AI) software can detect and may delineate ICH extent on brain CT. We evaluated e-ASPECTS software (Brainomix Ltd... Read More about Evaluating artificial intelligence software for delineating hemorrhage extent on CT brain imaging in stroke: AI delineation of ICH on CT..

Investigating the feasibility, acceptability, and appropriation of a socially assistive robot among minority youth at-risk of self-harm: Results of 2 Mixed Methods Pilot Studies (2023)
Journal Article
Williams, A. J., Townsend, E., Naeche, N., Chapman-Nisar, A., Hollis, C., & Slovak, P. (2023). Investigating the feasibility, acceptability, and appropriation of a socially assistive robot among minority youth at-risk of self-harm: Results of 2 Mixed Methods Pilot Studies. JMIR Formative Research, 7(1), Article e52336. https://doi.org/10.2196/52336

Background: Minority youth are at an increased risk of experiencing self-harmful thoughts and behaviors. However, there is limited evidence of successful interventions to support young people in the moment of their distress. Digital interventions are... Read More about Investigating the feasibility, acceptability, and appropriation of a socially assistive robot among minority youth at-risk of self-harm: Results of 2 Mixed Methods Pilot Studies.

Neural Plasticity in Tinnitus Mechanisms (2023)
Journal Article
Wallace, M. N., & Palmer, A. R. (2023). Neural Plasticity in Tinnitus Mechanisms. Brain Sciences, 13(12), Article 1615. https://doi.org/10.3390/brainsci13121615

A resource for development and comparison of multimodal brain 3T MRI harmonisation approaches (2023)
Journal Article
Warrington, S., Ntata, A., Mougin, O., Campbell, J., Torchi, A., Craig, M., …Sotiropoulos, S. N. (2023). A resource for development and comparison of multimodal brain 3T MRI harmonisation approaches. Imaging Neuroscience, 1(2023), 1-27. https://doi.org/10.1162/imag_a_00042

Despite the huge potential of magnetic resonance imaging (MRI) in mapping and exploring the brain, MRI measures can often be limited in their consistency, reproducibility and accuracy which subsequently restricts their quantifiability. Nuisance nonbi... Read More about A resource for development and comparison of multimodal brain 3T MRI harmonisation approaches.

Supporting early‐career dementia researchers: Identifying support needs and ways forward via a European study (2023)
Journal Article
Dupont, C., Gilissen, J., Dassen, F. C. M., Branco, R. M., Heins, P., Heffernan, E., & Bartels, S. L. (2024). Supporting early‐career dementia researchers: Identifying support needs and ways forward via a European study. Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 20(2), 1321-1333. https://doi.org/10.1002/alz.13530

INTRODUCTION Early-career researchers contribute significantly to dementia research and clinical practice. However, a growing group of early-career dementia researchers (ECDRs) lack appropriate support throughout their careers. Thus, we aim to (i) e... Read More about Supporting early‐career dementia researchers: Identifying support needs and ways forward via a European study.

BASIL: A Toolbox for Perfusion Quantification using Arterial Spin Labelling (2023)
Journal Article
Chappell, M. A., Kirk, T. F., Craig, M. S., McConnell, F. A. K., Zhao, M. Y., MacIntosh, B. J., …Woolrich, M. W. (2023). BASIL: A Toolbox for Perfusion Quantification using Arterial Spin Labelling. Imaging Neuroscience, https://doi.org/10.1162/imag_a_00041

Arterial Spin Labelling (ASL) MRI is now an established non-invasive method to quantify cerebral blood flow and is increasingly being used in a variety of neuroimaging applications. With standard ASL acquisition protocols widely available, there is a... Read More about BASIL: A Toolbox for Perfusion Quantification using Arterial Spin Labelling.

Transforming Workplace Learning: Implementing Mental Health First Aid Programmes at Work (2023)
Presentation / Conference Contribution
Dulal-Arthur, T., Siddiqui, M., Vaughan, B., Thomson, L., Bartle, C., Hassard, J., & Blake, H. (2023). Transforming Workplace Learning: Implementing Mental Health First Aid Programmes at Work. In ICERI2023 Proceedings. https://doi.org/10.21125/iceri.2023.1317

Traditional conceptualisations of workplace learning focus on enhancing professional skills and knowledge related to job performance. However, considering the increased prevalence and impact of mental health challenges in the workplace, it is imperat... Read More about Transforming Workplace Learning: Implementing Mental Health First Aid Programmes at Work.