All Outputs (378)

Inferring the basis of binaural detection with a modified autoencoder (2023)
Journal Article
Smith, S., Sollini, J., & Akeroyd, M. A. (2023). Inferring the basis of binaural detection with a modified autoencoder. Frontiers in Neuroscience, 17, Article 1000079. https://doi.org/10.3389/fnins.2023.1000079

The binaural system utilizes interaural timing cues to improve the detection of auditory signals presented in noise. In humans, the binaural mechanisms underlying this phenomenon cannot be directly measured and hence remain contentious. As an alterna... Read More about Inferring the basis of binaural detection with a modified autoencoder.

Developing a Patient Care Pathway for Emotional Support around the point of Multiple Sclerosis diagnosis: A Stakeholder Engagement Study (2023)
Journal Article
Tindall, T., Topcu, G., Thomas, S., Bale, C., Evangelou, N., Drummond, A., & das Nair, R. (2023). Developing a Patient Care Pathway for Emotional Support around the point of Multiple Sclerosis diagnosis: A Stakeholder Engagement Study. Health Expectations, 26(2), 858-868. https://doi.org/10.1111/hex.13711

Background: Diagnosing multiple sclerosis (MS) can be a lengthy process, which can impact psychological wellbeing, condition management, and future engagement with health services. Therefore, providing timely and appropriate emotional support may imp... Read More about Developing a Patient Care Pathway for Emotional Support around the point of Multiple Sclerosis diagnosis: A Stakeholder Engagement Study.

Long-term clinical and cost-effectiveness of a therapist-supported online remote behavioural intervention for tics in children and adolescents: extended 12- and 18-month follow-up of a single-blind randomised controlled trial (2023)
Journal Article
Hollis, C., Hall, C. L., Khan, K., Jones, R., Marston, L., Le Novere, M., …Murphy, T. (2023). Long-term clinical and cost-effectiveness of a therapist-supported online remote behavioural intervention for tics in children and adolescents: extended 12- and 18-month follow-up of a single-blind randomised controlled trial. Journal of Child Psychology and Psychiatry, 64(6), 941-951. https://doi.org/10.1111/jcpp.13756

Background: Little is known about the long-term effectiveness of behavioural therapy for tics. We aimed to assess the long-term clinical and cost-effectiveness of online therapist-supported exposure and response prevention (ERP) therapy for tics 12 a... Read More about Long-term clinical and cost-effectiveness of a therapist-supported online remote behavioural intervention for tics in children and adolescents: extended 12- and 18-month follow-up of a single-blind randomised controlled trial.

Patient and Public Involvement and Engagement for PhD Students (2023)
Preprint / Working Paper
Gladman, J. R. F., Stocks, J., Phillips, B., Horobin, A., Wragg, A., Mundey, M., …Humes, D. (2022). Patient and Public Involvement and Engagement for PhD Students

This paper aims to provide useful advice regarding the development of skills for patient and public involvement and engagement (PPIE) in research. The authors of this paper comprise experienced PhD supervisors and trainers, researchers leading PPIE a... Read More about Patient and Public Involvement and Engagement for PhD Students.

The pre-Descemet's layer (Dua's layer, also known as the Dua-Fine layer and the pre-posterior limiting lamina layer): Discovery, characterisation, clinical and surgical applications, and the controversy (2023)
Journal Article
Dua, H. S., Freitas, R., Mohammed, I., Ting, D. S., & Said, D. G. (2023). The pre-Descemet's layer (Dua's layer, also known as the Dua-Fine layer and the pre-posterior limiting lamina layer): Discovery, characterisation, clinical and surgical applications, and the controversy. Progress in Retinal and Eye Research, 97, Article 101161. https://doi.org/10.1016/j.preteyeres.2022.101161

The pre-Descemet's layer/Dua's layer, also termed the Dua-Fine layer and the pre-posterior limiting lamina layer, lies anterior to the Descemet's membrane in the cornea, is 10 μ m (range 6-16) thick, made predominantly of type I and some type VI coll... Read More about The pre-Descemet's layer (Dua's layer, also known as the Dua-Fine layer and the pre-posterior limiting lamina layer): Discovery, characterisation, clinical and surgical applications, and the controversy.

A Preliminary Psychometric Case Study of the Music in Dementia Assessment Scales: European Portuguese Version (Midas-PT) (2023)
Journal Article
Sousa, L., Moura, B., McDermott, O., & Fernandes, L. (2023). A Preliminary Psychometric Case Study of the Music in Dementia Assessment Scales: European Portuguese Version (Midas-PT). Acta Médica Portuguesa, 36(11), 731-739. https://doi.org/10.20344/amp.18763

Introduction: Music in Dementia Assessment Scales (MiDAS) is a standardized outcome measure aiming to capture the effects of music-based interventions in patients with dementia. It is a unique instrument regarding its specificity, with the potential... Read More about A Preliminary Psychometric Case Study of the Music in Dementia Assessment Scales: European Portuguese Version (Midas-PT).

A comparison of temporal pathways to self-harm in young people compared to adults: A pilot test of the Card Sort Task for Self-harm online using Indicator Wave Analysis (2023)
Journal Article
Lockwood, J., Babbage, C., Bird, K., Thynne, I., Barsky, A., Clarke, D. D., & Townsend, E. (2023). A comparison of temporal pathways to self-harm in young people compared to adults: A pilot test of the Card Sort Task for Self-harm online using Indicator Wave Analysis. Frontiers in Psychiatry, 13, Article 938003. https://doi.org/10.3389/fpsyt.2022.938003

Background: Self-harm is complex, multifaceted, and dynamic, typically starts in adolescence, and is prevalent in young people. A novel research tool (the Card Sort Task for Self-harm; CaTS) offers a systematic approach to understanding this complexi... Read More about A comparison of temporal pathways to self-harm in young people compared to adults: A pilot test of the Card Sort Task for Self-harm online using Indicator Wave Analysis.

Young People’s Trust in Cocreated Web-Based Resources to Promote Mental Health Literacy: Focus Group Study (2023)
Journal Article
Ito-Jaeger, S., Perez Vallejos, E., Logathasan, S., Curran, T., & Crawford, P. (2023). Young People’s Trust in Cocreated Web-Based Resources to Promote Mental Health Literacy: Focus Group Study. JMIR Mental Health, 10, Article e38346. https://doi.org/10.2196/38346

Background:
There is a pressing need to create resources to promote mental health literacy among young people. Digital media is one of the methods that can be used to successfully promote mental health literacy. Although digital mental health resour... Read More about Young People’s Trust in Cocreated Web-Based Resources to Promote Mental Health Literacy: Focus Group Study.

Clinically Translatable Transcrocetin Delivery Platform for Correction of Tumor Hypoxia and Enhancement of Radiation Therapy Effects (2023)
Journal Article
Diringer, M., Coliat, P., Mathieu, C., Laurent, N., Mura, C., Banerjee, M., …Detappe, A. (2023). Clinically Translatable Transcrocetin Delivery Platform for Correction of Tumor Hypoxia and Enhancement of Radiation Therapy Effects. Small, 19(12), Article 2205961. https://doi.org/10.1002/smll.202205961

Improving the tumor reoxygenation to sensitize the tumor to radiation therapy is a cornerstone in radiation oncology. Here, the pre‐clinical development of a clinically transferable liposomal formulation encapsulating trans sodium crocetinate (NP TSC... Read More about Clinically Translatable Transcrocetin Delivery Platform for Correction of Tumor Hypoxia and Enhancement of Radiation Therapy Effects.

Establishing a Core Domain Set for early-phase clinical trials of electrical stimulation interventions for tinnitus in adults: protocol for an online Delphi study (2022)
Journal Article
Labree, B., Hoare, D. J., Fackrell, K., Hall, D. A., Gascoyne, L. E., & Sereda, M. (2022). Establishing a Core Domain Set for early-phase clinical trials of electrical stimulation interventions for tinnitus in adults: protocol for an online Delphi study. Trials, 23(1), Article 1039. https://doi.org/10.1186/s13063-022-07020-2

Background: Tinnitus is the awareness of a sound in the ear or head in the absence of an external source. It affects around 10–15% of people and current treatment options are limited. Experimental treatments include various forms of electrical stimul... Read More about Establishing a Core Domain Set for early-phase clinical trials of electrical stimulation interventions for tinnitus in adults: protocol for an online Delphi study.

Mental health in clinically referred children and young people before and during the Covid-19 pandemic (2022)
Journal Article
Sayal, K., Partlett, C., Bhardwaj, A., Dubicka, B., Marshall, T., Gledhill, J., …Montgomery, A. (2023). Mental health in clinically referred children and young people before and during the Covid-19 pandemic. European Child and Adolescent Psychiatry, 32(12), 2657–2666. https://doi.org/10.1007/s00787-022-02115-2

The Covid-19 pandemic and mitigation approaches, including lockdowns and school closures, are thought to have negatively impacted children and young people’s (CYP) mental health. However, the impact for clinically referred CYP is less clear. We inves... Read More about Mental health in clinically referred children and young people before and during the Covid-19 pandemic.

A cross sectional survey on UK older adult’s attitudes to ageing, dementia and positive psychology attributes (2022)
Journal Article
Thelu, M., Webster, B., Jones, K., & Orrell, M. (2022). A cross sectional survey on UK older adult’s attitudes to ageing, dementia and positive psychology attributes. BMC Geriatrics, 22, Article 837. https://doi.org/10.1186/s12877-022-03539-w

Background
With an increasingly ageing population worldwide, the predominant attitude towards ageing is still negative. Negative stereotypes have detrimental effects on individuals’ physical and mental health. Evidence is required about factors that... Read More about A cross sectional survey on UK older adult’s attitudes to ageing, dementia and positive psychology attributes.

Evolution of Type D Personality Traits After Cochlear Implantation in Severely Hearing Impaired Adults 55 Years and Older: An Exploratory Prospective, Longitudinal, Controlled, Multicenter Study (2022)
Journal Article
Andries, E., Bieńkowska, K., Świerniak, W., Skarżyński, P. H., Skarżyński, H., Calvino, M., …Mertens, G. (2022). Evolution of Type D Personality Traits After Cochlear Implantation in Severely Hearing Impaired Adults 55 Years and Older: An Exploratory Prospective, Longitudinal, Controlled, Multicenter Study. Otology and Neurotology, 43(8), e865-e871. https://doi.org/10.1097/MAO.0000000000003622

Purpose To study the evolution of type D personality traits in older adults after cochlear implantation compared with a control group of severely hearing impaired older adults who did not receive a cochlear implant (CI). The influence of COVID-19 on... Read More about Evolution of Type D Personality Traits After Cochlear Implantation in Severely Hearing Impaired Adults 55 Years and Older: An Exploratory Prospective, Longitudinal, Controlled, Multicenter Study.

Delay of endothelial cell senescence protects cerebral barrier against age-related dysfunction: role of senolytics and senomorphics (2022)
Journal Article
Ya, J., Reskiawan, R., Kadir, R. R. A., & Bayraktutan, U. (2023). Delay of endothelial cell senescence protects cerebral barrier against age-related dysfunction: role of senolytics and senomorphics. Tissue Barriers, 11(3), Article 2103353. https://doi.org/10.1080/21688370.2022.2103353

Accumulation of senescent cells in cerebrovasculature is thought to play an important role in age-related disruption of blood–brain barrier (BBB). Using an in vitro model of human BBB, composed of brain microvascular endothelial cells (BMECs), astroc... Read More about Delay of endothelial cell senescence protects cerebral barrier against age-related dysfunction: role of senolytics and senomorphics.

Systems and Processes that Enable Progress for Older Forensic Mental Health Patients (2022)
Journal Article
Walker, K., Furtado, V., Yates, J., Dening, T., Völlm, B., & Griffiths, C. (2023). Systems and Processes that Enable Progress for Older Forensic Mental Health Patients. International Journal of Forensic Mental Health, 22(2), 93-104. https://doi.org/10.1080/14999013.2022.2080304

Older forensic mental health patients have complex needs and requirements; service provision is required to address mental health, offending risk and issues associated with aging (geriatric care). This study aimed to identify the systems and processe... Read More about Systems and Processes that Enable Progress for Older Forensic Mental Health Patients.

AB1432 THE ASSOCIATION OF PAINFUL AND NON-PAINFUL COMORBIDITIES WITH CENTRAL MECHANISMS OF KNEE PAIN (2022)
Presentation / Conference Contribution
Lewis, H., Chaplin, W., Mcwilliams, D., Millar, B., Shahtaheri, S., Gladman, J., & Walsh, D. (2022). AB1432 THE ASSOCIATION OF PAINFUL AND NON-PAINFUL COMORBIDITIES WITH CENTRAL MECHANISMS OF KNEE PAIN. Annals of the Rheumatic Diseases, 81(Suppl 1), 1822. https://doi.org/10.1136/annrheumdis-2022-eular.1586

Prevalence of Victimisation in Autistic Individuals: A Systematic Review and Meta-Analysis (2022)
Journal Article
Trundle, G., Jones, K. A., Ropar, D., & Egan, V. (2023). Prevalence of Victimisation in Autistic Individuals: A Systematic Review and Meta-Analysis. Trauma, Violence, and Abuse, 24(4), 2282-2296. https://doi.org/10.1177/15248380221093689

Autistic individuals are at an increased risk of experiencing victimisation. Previous reviews have focussed specific types of victimisation. Thus, a clearer picture considering the range of victimisation experiences autistic people face is required.... Read More about Prevalence of Victimisation in Autistic Individuals: A Systematic Review and Meta-Analysis.

Perfusion Imaging for Endovascular Thrombectomy in Acute Ischemic Stroke Is Associated With Improved Functional Outcomes in the Early and Late Time Windows (2022)
Journal Article
Dhillon, P. S., Butt, W., Podlasek, A., McConachie, N., Lenthall, R., Nair, S., …England, T. J. (2022). Perfusion Imaging for Endovascular Thrombectomy in Acute Ischemic Stroke Is Associated With Improved Functional Outcomes in the Early and Late Time Windows. Stroke, 53(9), 2770–2778. https://doi.org/10.1161/STROKEAHA.121.038010

Background: The impact on clinical outcomes of patient selection using perfusion imaging for endovascular thrombectomy (EVT) in patients with acute ischemic stroke presenting beyond 6 hours from onset remains undetermined in routine clinical practice... Read More about Perfusion Imaging for Endovascular Thrombectomy in Acute Ischemic Stroke Is Associated With Improved Functional Outcomes in the Early and Late Time Windows.

Association between anesthesia modality and clinical outcomes following endovascular stroke treatment in the extended time window (2022)
Journal Article
Dhillon, P. S., Butt, W., Podlasek, A., McConachie, N., Lenthall, R., Nair, S., …England, T. J. (2023). Association between anesthesia modality and clinical outcomes following endovascular stroke treatment in the extended time window. Journal of NeuroInterventional Surgery, 15(5), 478-482. https://doi.org/10.1136/neurintsurg-2022-018846

Background: There is a paucity of data on anesthesia-related outcomes for endovascular treatment (EVT) in the extended window (>6 hours from ischemic stroke onset). We compared functional and safety outcomes between local anesthesia (LA) without seda... Read More about Association between anesthesia modality and clinical outcomes following endovascular stroke treatment in the extended time window.

Sustaining interventions in care homes initiated by quality improvement projects: a qualitative study (2022)
Journal Article
Devi, R., Martin, G. P., Banerjee, J., Gladman, J. R., Dening, T., Barat, A., & Gordon, A. L. (2022). Sustaining interventions in care homes initiated by quality improvement projects: a qualitative study. BMJ Quality and Safety, 32(11), 665-675. https://doi.org/10.1136/bmjqs-2021-014345

Introduction: Inadequate and varied quality of care in care homes has led to a proliferation of quality improvement (QI) projects. This study examined the sustainability of interventions initiated by such projects. Method: This qualitative study expl... Read More about Sustaining interventions in care homes initiated by quality improvement projects: a qualitative study.