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Benefits to speech perception in noise from the binaural integration of electric and acoustic signals in simulated unilateral deafness (2016)
Journal Article
Ma, N., Morris, S. D., & Kitterick, P. T. (in press). Benefits to speech perception in noise from the binaural integration of electric and acoustic signals in simulated unilateral deafness. Ear and Hearing, 37(3), https://doi.org/10.1097/AUD.0000000000000252

Objectives: This study used vocoder simulations with normal-hearing (NH) listeners to (a) measure their ability to integrate speech information from a NH ear and a simulated cochlear implant (CI); and (b) investigate whether binaural integration is d... Read More about Benefits to speech perception in noise from the binaural integration of electric and acoustic signals in simulated unilateral deafness.

A comparison of phase imaging and quantitative susceptibility mapping in the imaging of multiple sclerosis lesions at ultrahigh field (2016)
Journal Article
Cronin, M. J., Wharton, S., Al-Radaideh, A., Constantinescu, C., Evangelou, N., Bowtell, R. W., & Gowland, P. A. (2016). A comparison of phase imaging and quantitative susceptibility mapping in the imaging of multiple sclerosis lesions at ultrahigh field. Magnetic Resonance Materials in Physics, Biology and Medicine, 29(3), 543-557. https://doi.org/10.1007/s10334-016-0560-5

Objective

The aim of this study was to compare the use of high-resolution phase and QSM images acquired at ultra-high field in the investigation of multiple sclerosis (MS) lesions with peripheral rings, and to discuss their usefulness for drawing... Read More about A comparison of phase imaging and quantitative susceptibility mapping in the imaging of multiple sclerosis lesions at ultrahigh field.

Choosing which ear to implant in adult candidates with functional residual hearing (2016)
Journal Article
Fielden, C. A., Mehta, R. L., & Kitterick, P. T. (in press). Choosing which ear to implant in adult candidates with functional residual hearing. Cochlear Implants International, 17(sup1), https://doi.org/10.1080/14670100.2016.1155805

This study examined whether audiologists consider the potential benefits of contralateral hearing aid use following cochlear implantation when recommending which ear to implant in UK adult candidates with residual hearing. Thirty-four audiologists fr... Read More about Choosing which ear to implant in adult candidates with functional residual hearing.

Predicting speech perception outcomes following cochlear implantation in adults with unilateral deafness or highly asymmetric hearing loss (2016)
Journal Article
Kitterick, P. T., & Lucas, L. (in press). Predicting speech perception outcomes following cochlear implantation in adults with unilateral deafness or highly asymmetric hearing loss. Cochlear Implants International, 17(sup 1), https://doi.org/10.1080/14670100.2016.1155806

Unilateral deafness and highly-asymmetric hearing loss can impair listening abilities in everyday situations, create substantial audiological handicap, and reduce overall quality of life. Preliminary evidence from early-phase studies in adults sugges... Read More about Predicting speech perception outcomes following cochlear implantation in adults with unilateral deafness or highly asymmetric hearing loss.

Preliminary assessment of the feasibility of using AB words to assess candidacy in adults (2016)
Journal Article
Vickers, D. A., Riley, A., Ricaud, R., Verschuur, C., Cooper, S., Nunn, T., …Kitterick, P. T. (in press). Preliminary assessment of the feasibility of using AB words to assess candidacy in adults. Cochlear Implants International, 17(sup 1), https://doi.org/10.1080/14670100.2016.1161143

Background: Adult cochlear implant (CI) candidacy is assessed in part by the use of speech perception measures. In the United Kingdom the current cut-off point to fall within the CI candidacy range is a score of less than 50% on the BKB sentences pre... Read More about Preliminary assessment of the feasibility of using AB words to assess candidacy in adults.

Access to aidable residual hearing in adult candidates for cochlear implantation in the UK (2016)
Journal Article
Fielden, C. A., Hampton, R., Smith, S., & Kitterick, P. T. (in press). Access to aidable residual hearing in adult candidates for cochlear implantation in the UK. Cochlear Implants International, 17(sup 1), https://doi.org/10.1080/14670100.2016.1153836

Guidance from the National Institute for Health and Care Excellence (NICE) permits candidates to receive a cochlear implant provided they only hear sounds louder than 90 dB HL at 2 and 4 kHz. In some patients, their level of residual hearing may be s... Read More about Access to aidable residual hearing in adult candidates for cochlear implantation in the UK.

Parasympathetic nervous system dysfunction, as identified by pupil light reflex, and its possible connection to hearing impairment (2016)
Journal Article
Wang, Y., Zekveld, A. A., Naylor, G., Ohlenforst, B., Jansma, E. P., Lorens, A., …Kramer, S. E. (2016). Parasympathetic nervous system dysfunction, as identified by pupil light reflex, and its possible connection to hearing impairment. PLoS ONE, 11(4), Article e0153566. https://doi.org/10.1371/journal.pone.0153566

Context
Although the pupil light reflex has been widely used as a clinical diagnostic tool for autonomic nervous system dysfunction, there is no systematic review available to summarize the evidence that the pupil light reflex is a sensitive method... Read More about Parasympathetic nervous system dysfunction, as identified by pupil light reflex, and its possible connection to hearing impairment.

Suppression of PKC-α attenuates TNF-α-evoked cerebral barrier breakdown via regulations of MMP-2 and plasminogen–plasmin system (2016)
Journal Article
Abdullah, Z., & Bayraktutan, U. (2016). Suppression of PKC-α attenuates TNF-α-evoked cerebral barrier breakdown via regulations of MMP-2 and plasminogen–plasmin system. BBA - Molecular Basis of Disease, 1862(7), 1354-1366. https://doi.org/10.1016/j.bbadis.2016.03.014

Ischaemic stroke, accompanied by neuroinflammation, impairs blood-brain barrier integrity through a complex mechanism involving both protein kinase C (PKC) and urokinase. Using an in vitro model of human blood-brain barrier (BBB) composed of brain mi... Read More about Suppression of PKC-α attenuates TNF-α-evoked cerebral barrier breakdown via regulations of MMP-2 and plasminogen–plasmin system.

On detectable and meaningful speech-intelligibility benefits (2016)
Journal Article
Whitmer, W. M., McShefferty, D., & Akeroyd, M. A. (in press). On detectable and meaningful speech-intelligibility benefits. Advances in Experimental Medicine and Biology, 894, https://doi.org/10.1007/978-3-319-25474-6_47

The most important parameter that affects the ability to hear and understand speech in the presence of background noise is the signal-to-noise ratio (SNR). Despite decades of research in speech intelligibility, it is not currently known how much impr... Read More about On detectable and meaningful speech-intelligibility benefits.

The contribution of visual information to the perception of speech in noise with and without informative temporal fine structure (2016)
Journal Article
Stacey, P. C., Kitterick, P. T., Morris, S. D., & Sumner, C. J. (2016). The contribution of visual information to the perception of speech in noise with and without informative temporal fine structure. Hearing Research, 336, 17-28. https://doi.org/10.1016/j.heares.2016.04.002

Understanding what is said in demanding listening situations is assisted greatly by looking at the face of a talker. Previous studies have observed that normal-hearing listeners can benefit from this visual information when a talker’s voice is presen... Read More about The contribution of visual information to the perception of speech in noise with and without informative temporal fine structure.

White matter microstructural changes in adolescent anorexia nervosa including an exploratory longitudinal study (2016)
Journal Article
Vogel, K., Timmers, I., Kumar, V., Nickl-Jockschat, T., Bastiani, M., Roebroek, A., …Seitz, J. (2016). White matter microstructural changes in adolescent anorexia nervosa including an exploratory longitudinal study. NeuroImage: Clinical, 11, 614-621. https://doi.org/10.1016/j.nicl.2016.04.002

Background

Anorexia nervosa (AN) often begins in adolescence, however, the understanding of the underlying pathophysiology at this developmentally important age is scarce, impeding early interventions. We used diffusion tensor imaging (DTI) to inv... Read More about White matter microstructural changes in adolescent anorexia nervosa including an exploratory longitudinal study.

Neural correlates of hyperalgesia in the monosodium iodoacetate model of osteoarthritis pain (2016)
Journal Article
Abaei, M., Sagar, D. R., Stockley, E. G., Spicer, C. H., Prior, M., Chapman, V., & Auer, D. P. (in press). Neural correlates of hyperalgesia in the monosodium iodoacetate model of osteoarthritis pain. Molecular Pain, 12, https://doi.org/10.1177/1744806916642445

Background: The mechanisms driving osteoarthritic pain remain poorly understood, but there is increasing evidence for a role of the central nervous system in the chronification of pain.We used functional magnetic resonance imaging to investigate the... Read More about Neural correlates of hyperalgesia in the monosodium iodoacetate model of osteoarthritis pain.

Contralateral acoustic hearing aid use in adult unilateral cochlear implant recipients: current provision, practice, and clinical experience in the UK (2016)
Journal Article
Fielden, C. A., & Kitterick, P. T. (in press). Contralateral acoustic hearing aid use in adult unilateral cochlear implant recipients: current provision, practice, and clinical experience in the UK. Cochlear Implants International, 17(3), https://doi.org/10.1080/14670100.2016.1162382

Objectives: The study surveyed practising cochlear implant audiologists with the aim of: (1) characterising UK clinical practice around the management and fitting of a contralateral hearing aid in adult unilateral cochlear implant users (‘bimodal aid... Read More about Contralateral acoustic hearing aid use in adult unilateral cochlear implant recipients: current provision, practice, and clinical experience in the UK.

Intravenous tranexamic acid for hyperacute primary intracerebral hemorrhage: protocol for a randomized, placebo-controlled trial (2016)
Journal Article
Sprigg, N., Robson, K., Bath, P. M., Dineen, R. A., Roberts, I., Robinson, T., …Beredzie, M. (2016). Intravenous tranexamic acid for hyperacute primary intracerebral hemorrhage: protocol for a randomized, placebo-controlled trial. International Journal of Stroke, 11(6), https://doi.org/10.1177/1747493016641960

Rationale: Outcome after intracerebral hemorrhage remains poor. Tranexamic acid is easy to administer, readily available, inexpensive, and effective in other hemorrhagic conditions.

Aim: This randomized trial aims to test the hypothesis that intra... Read More about Intravenous tranexamic acid for hyperacute primary intracerebral hemorrhage: protocol for a randomized, placebo-controlled trial.

A randomized controlled trial to evaluate the benefits of a multimedia educational program for first-time hearing aid users (2016)
Journal Article
Ferguson, M. A., Brandreth, M., Brassington, W., Leighton, P., & Wharrad, H. (2016). A randomized controlled trial to evaluate the benefits of a multimedia educational program for first-time hearing aid users. Ear and Hearing, 37(2), https://doi.org/10.1097/AUD.0000000000000237

Objectives: The aims of this study were to (1) develop a series of short interactive videos (or reusable learning objects [RLOs]) covering a broad range of practical and psychosocial issues relevant to the auditory rehabilitation for first-time heari... Read More about A randomized controlled trial to evaluate the benefits of a multimedia educational program for first-time hearing aid users.

Can illness beliefs, from the common-sense model, prospectively predict adherence to self-management behaviours?: a systematic review and meta-analysis (2016)
Journal Article
Aujla, N., Walker, M., Sprigg, N., Abrams, K., Massey, A., & Vedhara, K. (in press). Can illness beliefs, from the common-sense model, prospectively predict adherence to self-management behaviours?: a systematic review and meta-analysis. Psychology and Health, 2016, https://doi.org/10.1080/08870446.2016.1153640

Objective: To determine whether people’s beliefs about their illness, conceptualised by the common sense model (CSM), can prospectively predict adherence to self-management behaviours (including, attendance, medication, diet and exercise) in adults w... Read More about Can illness beliefs, from the common-sense model, prospectively predict adherence to self-management behaviours?: a systematic review and meta-analysis.

The Glasgow Benefit Inventory: a systematic review of the use and value of an otorhinolaryngological generic patient-recorded outcome measure (2016)
Journal Article
Hendry, J., Chin, A., Swan, I. R., Akeroyd, M. A., & Browning, G. G. (2016). The Glasgow Benefit Inventory: a systematic review of the use and value of an otorhinolaryngological generic patient-recorded outcome measure. Clinical Otolaryngology, 41(3), https://doi.org/10.1111/coa.12518

The Glasgow Benefit Inventory (GBI) is a validated, generic patient-recorded outcome measure widely used in otolaryngology to report change in quality of life post-intervention.To date, no systematic review has made (i) a quality assessment of report... Read More about The Glasgow Benefit Inventory: a systematic review of the use and value of an otorhinolaryngological generic patient-recorded outcome measure.

Understanding User Reactions and Interactions with an Internet-Based Intervention for Tinnitus Self-Management: Mixed-Methods Process Evaluation (2016)
Other
Greenwell, K., Sereda, M., Coulson, N., & Hoare, D. J. (2016). Understanding User Reactions and Interactions with an Internet-Based Intervention for Tinnitus Self-Management: Mixed-Methods Process Evaluation

Background:

Tinnitus is a common symptom that can affect an individual’s quality of life, requiring psychological support that is not readily accessible. Internet-based interventions have the potential to reduce the disparity in access to psycholo... Read More about Understanding User Reactions and Interactions with an Internet-Based Intervention for Tinnitus Self-Management: Mixed-Methods Process Evaluation.