All Outputs (1129)

Signalling pathways involved in ribonuclease-7 expression (2010)
Journal Article
Mohammed, I., Yeung, A., Abedin, A., Hopkinson, A., & Dua, H. S. (2011). Signalling pathways involved in ribonuclease-7 expression. Cellular and Molecular Life Sciences, 68(11), 1941-1952. https://doi.org/10.1007/s00018-010-0540-2

Antimicrobial peptides are host defence molecules that play a potential role in preventing infection at the epithelial surfaces. Ribonuclease (RNase)-7 has been shown to possess a broad spectrum of microbicidal activity against various pathogens. Her... Read More about Signalling pathways involved in ribonuclease-7 expression.

Influence of cellulose on ion diffusivity in 1-ethyl-3-methyl-imidazolium acetate cellulose solutions (2010)
Journal Article
Lovell, C. S., Walker, A., Damion, R. A., Radhi, A., Tanner, S. F., Budtova, T., & Ries, M. E. (2010). Influence of cellulose on ion diffusivity in 1-ethyl-3-methyl-imidazolium acetate cellulose solutions. Biomacromolecules, 11(11), 2927-2935. https://doi.org/10.1021/bm1006807

Solutions of microcrystalline cellulose in 1-ethyl-3-methyl-imidazolium acetate have been investigated using pulsedfield gradient 1H NMR. In all cases the geometrically larger cation was found to diffuse faster than the smaller anion. Arrhenius tempe... Read More about Influence of cellulose on ion diffusivity in 1-ethyl-3-methyl-imidazolium acetate cellulose solutions.

Comparative transcriptional profiling of the limbal epithelial crypt demonstrates its putative stem cell niche characteristics (2010)
Journal Article
Kulkarni, B. B., Tighe, P. J., Mohammed, I., Yeung, A. M., Powe, D. G., Hopkinson, A., …Dua, H. S. (2010). Comparative transcriptional profiling of the limbal epithelial crypt demonstrates its putative stem cell niche characteristics. BMC Genomics, 11(1), Article 526. https://doi.org/10.1186/1471-2164-11-526

Background: The Limbal epithelial crypt (LEC) is a solid cord of cells, approximately 120 microns long. It arises from the undersurface of interpalisade rete ridges of the limbal palisades of Vogt and extends deeper into the limbal stroma parallel or... Read More about Comparative transcriptional profiling of the limbal epithelial crypt demonstrates its putative stem cell niche characteristics.

Localization and Gene Expression of Human β-Defensin 9 at the Human Ocular Surface Epithelium (2010)
Journal Article
Mohammed, I., Suleman, H., Otri, A. M., Kulkarni, B. B., Chen, P., Hopkinson, A., & Dua, H. S. (2010). Localization and Gene Expression of Human β-Defensin 9 at the Human Ocular Surface Epithelium. Investigative Ophthalmology & Visual Science, 51(9), 4677-4682. https://doi.org/10.1167/iovs.10-5334

Purpose: Antimicrobial peptides (AMPs) are multifunctional host defense molecules. Human β-defensin 9 (HBD9) has previously been shown to be downregulated during ocular surface (OS) infection or inflammation. Here, the authors aimed to study localiz... Read More about Localization and Gene Expression of Human β-Defensin 9 at the Human Ocular Surface Epithelium.

Ex vivo confocal microscopy of human corneal nerves (2010)
Journal Article
Al-Aqaba, M. A., Alomar, T., Miri, A., Fares, U., Otri, A. M., & Dua, H. S. (2010). Ex vivo confocal microscopy of human corneal nerves. British Journal of Ophthalmology, 94(9), 1251-1257. https://doi.org/10.1136/bjo.2009.178244

Covert auditory spatial orienting: An evaluation of the spatial relevance hypothesis (2009)
Journal Article
Roberts, K. L., Summerfield, A. Q., & Hall, D. A. (in press). Covert auditory spatial orienting: An evaluation of the spatial relevance hypothesis. Journal of Experimental Psychology: Human Perception and Performance, 35(4), 1178-1191. https://doi.org/10.1037/a0014249

Architecture and distribution of human corneal nerves (2009)
Journal Article
Al-Aqaba, M. A., Fares, U., Suleman, H., Lowe, J., & Dua, H. S. (2010). Architecture and distribution of human corneal nerves. British Journal of Ophthalmology, 94(6), 784-789. https://doi.org/10.1136/bjo.2009.173799

Interconversion of the National Institutes of Health Stroke Scale and Scandinavian Stroke Scale in acute stroke (2009)
Journal Article
Gray, L. J., Ali, M., Lyden, P. D., & Bath, P. M. (2009). Interconversion of the National Institutes of Health Stroke Scale and Scandinavian Stroke Scale in acute stroke. Journal of Stroke and Cerebrovascular Diseases, 18(6), https://doi.org/10.1016/j.jstrokecerebrovasdis.2009.02.003

Effect of telmisartan on functional outcome, recurrence, and blood pressure in patients with acute mild ischemic stroke: a PRoFESS subgroup analysis (2009)
Journal Article
Bath, P. M., Martin, R. H., Palesch, Y., Cotton, D., Yusuf, S., Sacco, R. L., …Roberts, R. (2009). Effect of telmisartan on functional outcome, recurrence, and blood pressure in patients with acute mild ischemic stroke: a PRoFESS subgroup analysis. Stroke, 40(11), 3541-3546. https://doi.org/10.1161/strokeaha.109.555623

Background and Purpose: High blood pressure (BP) is common in acute ischemic stroke and associated independently with a poor functional outcome. However, the management of BP acutely remains unclear because no large trials have been completed. Metho... Read More about Effect of telmisartan on functional outcome, recurrence, and blood pressure in patients with acute mild ischemic stroke: a PRoFESS subgroup analysis.

Granulocyte-colony stimulating factor in experimental stroke and its effects on infarct size and functional outcome: a systematic review (2009)
Journal Article
England, T. J., Gibson, C. L., & Bath, P. M. (2009). Granulocyte-colony stimulating factor in experimental stroke and its effects on infarct size and functional outcome: a systematic review. Brain Research, 62(1), 71-82. https://doi.org/10.1016/j.brainresrev.2009.09.002

Background Granulocyte-colony stimulating factor (G-CSF) shows promise as a treatment for stroke. This systematic review assesses G-CSF in experimental ischaemic stroke. Methods Relevant studies were identified with searches of Medline, Embase a... Read More about Granulocyte-colony stimulating factor in experimental stroke and its effects on infarct size and functional outcome: a systematic review.

Correlation between the pattern of myopic fundal changes and the axis of astigmatism of the eye (2009)
Journal Article
Ahmad, R., Al-Aqaba, M. A., Fares, U., Otri, A. M., Miri, A., Said, D. G., & Dua, H. S. (2010). Correlation between the pattern of myopic fundal changes and the axis of astigmatism of the eye. British Journal of Ophthalmology, 94(3), 307-310. https://doi.org/10.1136/bjo.2009.161794

Relationship between therapeutic changes in blood pressure and outcomes in acute stroke: a metaregression (2009)
Journal Article
Geeganage, C., & Bath, P. M. (in press). Relationship between therapeutic changes in blood pressure and outcomes in acute stroke: a metaregression. Hypertension, 54(4), https://doi.org/10.1161/hypertensionaha.109.133538

Both low and high blood pressure (BP) during the acute phase of stroke are associated independently with a poor outcome. Several small clinical trials have involved the alteration of BP and this study assessed the relationship between change in BP an... Read More about Relationship between therapeutic changes in blood pressure and outcomes in acute stroke: a metaregression.

Rapid suture management of post-keratoplasty astigmatism (2009)
Journal Article
Sarhan, A., Fares, U., Al-Aqaba, M., Miri, A., Otri, A., Said, D., & Dua, H. (2010). Rapid suture management of post-keratoplasty astigmatism. Eye, 24(4), 540-546. doi:10.1038/eye.2009.146

Antiplatelet activity should be measured routinely: no (2009)
Journal Article
Bath, P. M. (2009). Antiplatelet activity should be measured routinely: no. Stroke, 40(6), https://doi.org/10.1161/STROKEAHA.108.537647

Relationship between hyperacute blood pressure and outcome after ischemic stroke: data from the VISTA Collaboration (2009)
Journal Article
Sare, G. M., Ali, M., Shuaib, A., & Bath, P. M. (2009). Relationship between hyperacute blood pressure and outcome after ischemic stroke: data from the VISTA Collaboration. Stroke, 40(6), https://doi.org/10.1161/STROKEAHA.108.539155

Background and Purpose—High blood pressure (BP) is associated independently with poor outcome after acute ischemic stroke, although in most analyses “baseline” BP was measured 24 hours or more postictus, and not during the hyperacute period. Methods... Read More about Relationship between hyperacute blood pressure and outcome after ischemic stroke: data from the VISTA Collaboration.

Thigh-length compression stockings and DVT after stroke (2009)
Journal Article
Bath, P. M., & England, T. J. (2009). Thigh-length compression stockings and DVT after stroke. Lancet, 373(9679), 1923-1924. https://doi.org/10.1016/S0140-6736%2809%2960990-9

Speeding stroke recovery? A systematic review of amphetamine after stroke (2009)
Journal Article
Sprigg, N., & Bath, P. M. (2009). Speeding stroke recovery? A systematic review of amphetamine after stroke. Journal of the Neurological Sciences, 285(1-2), 3-9. https://doi.org/10.1016/j.jns.2009.04.040

Introduction: The use of drugs to enhance recovery (“rehabilitation pharmacology”) has been assessed. Amphetamine can improve outcome in experimental models of stroke, and several small clinical trials have assessed its use in stroke. Methods: Elec... Read More about Speeding stroke recovery? A systematic review of amphetamine after stroke.

Need for ethics approval and patient consent in clinical research (2009)
Journal Article
Bath, P. M., & Watson, A. R. (2009). Need for ethics approval and patient consent in clinical research. Stroke, 40(5), https://doi.org/10.1161/STROKEAHA.108.539080

Interventions for deliberately altering blood pressure in acute stroke (2009)
Journal Article
Geeganage, C., & Bath, P. M. (2009). Interventions for deliberately altering blood pressure in acute stroke. Stroke, 40(5), Article e390-e391. https://doi.org/10.1161/STROKEAHA.108.535849

Stem cells for enhancing recovery after stroke: a review (2009)
Journal Article
England, T. J., Martin, P., & Bath, P. M. (2009). Stem cells for enhancing recovery after stroke: a review. International Journal of Stroke, 4(2),

The potential application for stem cell therapy is vast, and development for use in ischaemic stroke is still in its infancy. Access to stem cells for research is contentious; however, stem cells are obtainable from both animal and human. Despite a... Read More about Stem cells for enhancing recovery after stroke: a review.