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All Outputs (128)

Intervention Planning for the Tinnitus E-Programme 2.0, an Internet-Based Cognitive Behavioral Intervention for Tinnitus (2021)
Journal Article
Greenwell, K., Sereda, M., Bradbury, K., Geraghty, A. W. A., Coulson, N. S., & Hoare, D. J. (2021). Intervention Planning for the Tinnitus E-Programme 2.0, an Internet-Based Cognitive Behavioral Intervention for Tinnitus. American Journal of Audiology, 30(2), 241-254. https://doi.org/10.1044/2021_AJA-20-00131

Purpose: The purpose of this study is to comprehensively describe the intervention planning process for the Tinnitus E-Programme 2.0, an Internet-based cognitive behavioral intervention for tinnitus.

Method: Theory-, evidence-, and person-based a... Read More about Intervention Planning for the Tinnitus E-Programme 2.0, an Internet-Based Cognitive Behavioral Intervention for Tinnitus.

Childhood pet ownership and multiple sclerosis: A systematic review and meta-analysis (2021)
Journal Article
Edwards, L., & Tench, C. (2021). Childhood pet ownership and multiple sclerosis: A systematic review and meta-analysis. Multiple Sclerosis and Related Disorders, 53, Article 103046. https://doi.org/10.1016/j.msard.2021.103046

Background

Many studies have been conducted investigating a range of environmental factors which have been implicated in the pathogenesis of multiple sclerosis (MS). We collated available data about exposure to domestic animals before symptom onse... Read More about Childhood pet ownership and multiple sclerosis: A systematic review and meta-analysis.

Examination of optimized protocols for pCASL: Sensitivity to macrovascular contamination, flow dispersion, and prolonged arterial transit time (2021)
Journal Article
Zhang, L. X., Woods, J. G., Okell, T. W., & Chappell, M. A. (2021). Examination of optimized protocols for pCASL: Sensitivity to macrovascular contamination, flow dispersion, and prolonged arterial transit time. Magnetic Resonance in Medicine, 86(4), 2208-2219. https://doi.org/10.1002/mrm.28839

Purpose
Previously, multi- post-labeling delays (PLD) pseudo-continuous arterial spin labeling (pCASL) protocols have been optimized for the estimation accuracy of the cerebral blood flow (CBF) with/without the arterial transit time (ATT) under a st... Read More about Examination of optimized protocols for pCASL: Sensitivity to macrovascular contamination, flow dispersion, and prolonged arterial transit time.

Tranexamic Acid for Prevention of Hematoma Expansion in Intracerebral Hemorrhage Patients With or Without Spot Sign (2021)
Journal Article
Ovesen, C., Jakobsen, J. C., Gluud, C., Steiner, T., Law, Z., Flaherty, K., …Christensen, H. (2021). Tranexamic Acid for Prevention of Hematoma Expansion in Intracerebral Hemorrhage Patients With or Without Spot Sign. Stroke, 52(8), 2629-2636. https://doi.org/10.1161/strokeaha.120.032426

Background and Purpose:
The computed tomography angiography or contrast-enhanced computed tomography based spot sign has been proposed as a biomarker for identifying on-going hematoma expansion in patients with acute intracerebral hemorrhage. We inv... Read More about Tranexamic Acid for Prevention of Hematoma Expansion in Intracerebral Hemorrhage Patients With or Without Spot Sign.

Multiple spatial reference frames underpin perceptual recalibration to audio-visual discrepancies (2021)
Journal Article
Watson, D. M., Akeroyd, M. A., Roach, N. W., & Webb, B. S. (2021). Multiple spatial reference frames underpin perceptual recalibration to audio-visual discrepancies. PLoS ONE, 16(5), 1-21. https://doi.org/10.1371/journal.pone.0251827

In dynamic multisensory environments, the perceptual system corrects for discrepancies arising between modalities. For instance, in the ventriloquism aftereffect (VAE), spatial disparities introduced between visual and auditory stimuli lead to a perc... Read More about Multiple spatial reference frames underpin perceptual recalibration to audio-visual discrepancies.

Designing a Mobile Eye Hospital to Support Health Systems in Resource-Scarce Environments (2021)
Journal Article
McMaster, D., & Clare, G. (2022). Designing a Mobile Eye Hospital to Support Health Systems in Resource-Scarce Environments. Disaster Medicine and Public Health Preparedness, 16(4), 1618-1622. https://doi.org/10.1017/dmp.2021.108

Eye health is an integral part of well-being that may be at increased risk when health service delivery is affected by sudden-onset disasters, complex humanitarian events, or conflict in resource-scarce environments. This study proposes a design plan... Read More about Designing a Mobile Eye Hospital to Support Health Systems in Resource-Scarce Environments.

Functional and diffusion MRI reveal the neurophysiological basis of neonates’ noxious-stimulus evoked brain activity (2021)
Journal Article
Baxter, L., Moultrie, F., Fitzgibbon, S., Aspbury, M., Mansfield, R., Bastiani, M., …Slater, R. (2021). Functional and diffusion MRI reveal the neurophysiological basis of neonates’ noxious-stimulus evoked brain activity. Nature Communications, 12, Article 2744. https://doi.org/10.1038/s41467-021-22960-0

Understanding the neurophysiology underlying pain perception in infants is central to improving early life pain management. In this multimodal MRI study, we use resting-state functional and white matter diffusion MRI to investigate individual variabi... Read More about Functional and diffusion MRI reveal the neurophysiological basis of neonates’ noxious-stimulus evoked brain activity.

European Stroke Organisation (ESO) guidelines on blood pressure management in acute ischaemic stroke and intracerebral haemorrhage (2021)
Journal Article
Sandset, E. C., Anderson, C. S., Bath, P. M., Christensen, H., Fischer, U., Manning, L. S., …Tsivgoulis, G. (2021). European Stroke Organisation (ESO) guidelines on blood pressure management in acute ischaemic stroke and intracerebral haemorrhage. European Stroke Journal, 6(2), XLVIII-LXXXIX. https://doi.org/10.1177/23969873211012133

Introduction: The optimal blood pressure (BP) management in acute ischaemic stroke (AIS) and acute intracerebral haemorrhage (ICH) remains controversial. These European Stroke Organisation (ESO) guidelines provide evidence-based recommendations to as... Read More about European Stroke Organisation (ESO) guidelines on blood pressure management in acute ischaemic stroke and intracerebral haemorrhage.

Clopidogrel with aspirin in High-risk patients with Acute Non-disabling Cerebrovascular Events II (CHANCE-2): rationale and design of a multicenter randomised trial (2021)
Journal Article
Wang, Y., Claiborne Johnston, S., Bath, P. M., Meng, X., Jing, J., Xie, X., …Li, H. (2021). Clopidogrel with aspirin in High-risk patients with Acute Non-disabling Cerebrovascular Events II (CHANCE-2): rationale and design of a multicenter randomised trial. Stroke and Vascular Neurology, 6(2), Article e000791. https://doi.org/10.1136/svn-2020-000791

Background: In patients with a minor ischaemic stroke or transient ischaemic attack (TIA), separate trials have shown that dual antiplatelet therapy with clopidogrel plus aspirin (clopidogrel–aspirin) or ticagrelor plus aspirin (ticagrelor–aspirin) a... Read More about Clopidogrel with aspirin in High-risk patients with Acute Non-disabling Cerebrovascular Events II (CHANCE-2): rationale and design of a multicenter randomised trial.

COVID-19 is associated with new symptoms of multiple sclerosis that are prevented by disease modifying therapies (2021)
Journal Article
Garjani, A., Middleton, R. M., Hunter, R., Tuite-Dalton, K. A., Coles, A., Dobson, R., …Evangelou, N. (2021). COVID-19 is associated with new symptoms of multiple sclerosis that are prevented by disease modifying therapies. Multiple Sclerosis and Related Disorders, 52, Article 102939. https://doi.org/10.1016/j.msard.2021.102939

Background

Infections can trigger exacerbations of multiple sclerosis (MS). The effects of the coronavirus disease 2019 (COVID-19) on MS are not known. The aim of this study was to understand the impact of COVID-19 on new and pre-existing symptoms... Read More about COVID-19 is associated with new symptoms of multiple sclerosis that are prevented by disease modifying therapies.

Cognitive assessment in multiple sclerosis clinical care: A qualitative evaluation of stakeholder perceptions and preferences (2021)
Journal Article
Elwick, H., Smith, L., Mhizha-Murira, J. R., Topcu, G., Leighton, P., Drummond, A., …Das Nair, R. (2022). Cognitive assessment in multiple sclerosis clinical care: A qualitative evaluation of stakeholder perceptions and preferences. Neuropsychological Rehabilitation, 32(7), 1456-1474. https://doi.org/10.1080/09602011.2021.1899942

There is a growing consensus that cognitive assessments should form part of routine clinical care in Multiple Sclerosis (MS). However, what remains unclear is which assessments are preferred by “stakeholders” (including people with MS, family members... Read More about Cognitive assessment in multiple sclerosis clinical care: A qualitative evaluation of stakeholder perceptions and preferences.

Early mortality outcomes of patients with fragility hip fracture and concurrent SARS-CoV-2 infection: a systematic review and meta-analysis (2021)
Journal Article
Alcock, H., Moppett, E., & Moppett, I. (2021). Early mortality outcomes of patients with fragility hip fracture and concurrent SARS-CoV-2 infection: a systematic review and meta-analysis. Bone & Joint Open, 2(5), 314-322. https://doi.org/10.1302/2633-1462.25.BJO-2020-0183.R1

Aims
Hip fracture is a common condition of the older, frailer person. This population is also at risk from SARS-CoV-2 infection. It is important to understand the impact of coexistent hip fracture and SARS-CoV-2 for informed decision-making at patie... Read More about Early mortality outcomes of patients with fragility hip fracture and concurrent SARS-CoV-2 infection: a systematic review and meta-analysis.

Cognitive Improvement After Cochlear Implantation in Older Adults With Severe or Profound Hearing Impairment: A Prospective, Longitudinal, Controlled, Multicenter Study (2021)
Journal Article
Mertens, G., Andries, E., Claes, A. J., Topsakal, V., Van de Heyning, P., Van Rompaey, V., …Lassaletta, L. (2021). Cognitive Improvement After Cochlear Implantation in Older Adults With Severe or Profound Hearing Impairment: A Prospective, Longitudinal, Controlled, Multicenter Study. Ear and Hearing, 42(3), 606-614. https://doi.org/10.1097/AUD.0000000000000962

OBJECTIVE: To compare the cognitive evolution of older adults with severe or profound hearing impairment after cochlear implantation with that of a matched group of older adults with severe hearing impairment who do not receive a cochlear implant (CI... Read More about Cognitive Improvement After Cochlear Implantation in Older Adults With Severe or Profound Hearing Impairment: A Prospective, Longitudinal, Controlled, Multicenter Study.

A set of equations for numerically calculating the interaural level difference in the horizontal plane (2021)
Journal Article
Akeroyd, M. A., Firth, J., Graetzer, S., & Smith, S. (2021). A set of equations for numerically calculating the interaural level difference in the horizontal plane. JASA Express Letters, 1(4), Article 044402. https://doi.org/10.1121/10.0004261

The variation of interaural level difference (ILD) with direction and frequency is particularly complex and convoluted. The purpose of this work was to determine a set of parametric equations that can be used to calculate ILDs continuously at any val... Read More about A set of equations for numerically calculating the interaural level difference in the horizontal plane.

Quantitative CT radiomics-based models for prediction of haematoma expansion and poor functional outcome in primary intracerebral haemorrhage (2021)
Journal Article
Pszczolkowski, S., Manzano-Patron, J. P., Law, Z. K., Krishnan, K., Ali, A., Bath, P. M., Sprigg, N., & Dineen, R. A. (2021). Quantitative CT radiomics-based models for prediction of haematoma expansion and poor functional outcome in primary intracerebral haemorrhage. European Radiology, 31, 7945-7959. https://doi.org/10.1007/s00330-021-07826-9

Objectives
To test radiomics-based features extracted from noncontrast CT of patients with spontaneous intracerebral haemorrhage for prediction of haematoma expansion and poor functional outcome and compare them with radiological signs and clinical... Read More about Quantitative CT radiomics-based models for prediction of haematoma expansion and poor functional outcome in primary intracerebral haemorrhage.

Accessing Voluntary HIV Testing in the Construction Industry: A Qualitative Analysis of Employee Interviews from the Test@Work Study (2021)
Journal Article
Somerset, S., Evans, C., & Blake, H. (2021). Accessing Voluntary HIV Testing in the Construction Industry: A Qualitative Analysis of Employee Interviews from the Test@Work Study. International Journal of Environmental Research and Public Health, 18(8), Article 4184. https://doi.org/10.3390/ijerph18084184

HIV, globally, remains a significant public health issue and community HIV testing can help to identify those with HIV at an early stage of disease. The workplace offers a prime location for provision of opt-in HIV testing as part of wider health pro... Read More about Accessing Voluntary HIV Testing in the Construction Industry: A Qualitative Analysis of Employee Interviews from the Test@Work Study.

The “Flying Intervention Team”: A Novel Stroke Care Concept for Rural Areas (2021)
Journal Article
Hubert, G. J., Kraus, F., Maegerlein, C., Platen, S., Friedrich, B., Kain, H.-U., Witton-Davies, T., Hubert, N. D., Zimmer, C., Bath, P. M., Audebert, H. J., & Haberl, R. L. (2021). The “Flying Intervention Team”: A Novel Stroke Care Concept for Rural Areas. Cerebrovascular Diseases, 50(4), 375–382. https://doi.org/10.1159/000514845

Background: Endovascular treatment of large vessel occlusion in acute ischemic stroke patients is difficult to establish in remote areas, and time dependency of treatment effect increases the urge to develop health care concepts for this population.... Read More about The “Flying Intervention Team”: A Novel Stroke Care Concept for Rural Areas.

Accumulation of Brain Hypointense Foci on Susceptibility-Weighted Imaging in Childhood Ataxia Telangiectasia (2021)
Journal Article
Dineen, R. A., Blanchard, C. C., Pszczolkowski, S., Paine, S., Prasad, M., Chow, G., …Auer, D. P. (2021). Accumulation of Brain Hypointense Foci on Susceptibility-Weighted Imaging in Childhood Ataxia Telangiectasia. American Journal of Neuroradiology, 42(6), 1144-1150. https://doi.org/10.3174/ajnr.a7107

Background and Purpose
Susceptibility-weighted imaging (SWI) hypointense cerebral lesions have been reported in adults with the inherited cerebellar neurodegenerative disorder ataxia telangiectasia (A-T). This study aims to establish the prevalence... Read More about Accumulation of Brain Hypointense Foci on Susceptibility-Weighted Imaging in Childhood Ataxia Telangiectasia.

Audiometric profiles and patterns of benefit: a data-driven analysis of subjective hearing difficulties and handicaps (2021)
Journal Article
Sanchez-Lopez, R., Dau, T., & Whitmer, W. M. (2022). Audiometric profiles and patterns of benefit: a data-driven analysis of subjective hearing difficulties and handicaps. International Journal of Audiology, 61(4), 301-310. https://doi.org/10.1080/14992027.2021.1905890

Objective: Hearing rehabilitation attempts to compensate for auditory dysfunction, reduce hearing difficulties and minimize participation restrictions that can lead to social isolation. However, there is no systematic approach to assess the quality o... Read More about Audiometric profiles and patterns of benefit: a data-driven analysis of subjective hearing difficulties and handicaps.