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Auditory attention causes gain enhancement and frequency sharpening at successive stages of cortical processing: evidence from human EEG (2018)
Journal Article
de Boer, J., & Krumbholz, K. (2018). Auditory attention causes gain enhancement and frequency sharpening at successive stages of cortical processing: evidence from human EEG. Journal of Cognitive Neuroscience, 30(6), 785-798. https://doi.org/10.1162/jocn_a_01245

Previous findings have suggested that auditory attention causes not only enhancement in neural processing gain, but also sharpening in neural frequency tuning in human auditory cortex. The current study was aimed to reexamine these findings, and inve... Read More about Auditory attention causes gain enhancement and frequency sharpening at successive stages of cortical processing: evidence from human EEG.

Live quantitative monitoring of mineral deposition in stem cells using tetracycline hydrochloride (2018)
Journal Article
Macri-Pellizzeri, L., De Melo, N., Ahmed, I., Grant, D. M., Scammell, B., & Sottile, V. (2018). Live quantitative monitoring of mineral deposition in stem cells using tetracycline hydrochloride. Tissue Engineering Part C Methods, 24(3), https://doi.org/10.1089/ten.TEC.2017.0400

The final stage of in vitro osteogenic differentiation is characterized by the production of mineral deposits containing calcium cations and inorganic phosphates, which populate the extracellular matrix surrounding the cell monolayer. Conventional hi... Read More about Live quantitative monitoring of mineral deposition in stem cells using tetracycline hydrochloride.

Changing health behaviour with rehabilitation in thoracic cancer: a systematic review and synthesis (2018)
Journal Article
Bayly, J., Wakefield, D., Hepgul, N., Wilcock, A., Higginson, I. J., & Maddocks, M. (2018). Changing health behaviour with rehabilitation in thoracic cancer: a systematic review and synthesis. Psycho-Oncology, 27(7), 1675-1694. https://doi.org/10.1002/pon.4684

Objectives: International guidelines recommend that rehabilitation be offered to people with thoracic cancer to improve symptoms, function and quality of life. When rehabilitation interventions require a change in behaviour, the use of theory and beh... Read More about Changing health behaviour with rehabilitation in thoracic cancer: a systematic review and synthesis.

A biophysical model of dynamic balancing of excitation and inhibition in fast oscillatory large-scale networks (2018)
Journal Article
Abeysuriya, R. G., Hadida, J., Sotiropoulos, S. N., Jbabdi, S., Becker, R., Hunt, B. A., …Woolrich, M. W. (in press). A biophysical model of dynamic balancing of excitation and inhibition in fast oscillatory large-scale networks. PLoS Computational Biology, 14(2), Article e1006007. https://doi.org/10.1371/journal.pcbi.1006007

Over long timescales, neuronal dynamics can be robust to quite large perturbations, such as changes in white matter connectivity and grey matter structure through processes including learning, aging, development and certain disease processes. One pos... Read More about A biophysical model of dynamic balancing of excitation and inhibition in fast oscillatory large-scale networks.

Magnetic resonance elastography (2018)
Book Chapter
McGrath, D. M. Magnetic resonance elastography. In A. Al Mayah (Ed.), Biomechanics of soft tissues: principles and applications. CRC Press

Magnetic resonance elastography (MRE) is a recently developed technology that uses MRI to measure the biomechanical properties of biological tissue, such as elasticity and viscosity. Due to its sensitivity to pathology-driven alterations in tissue bi... Read More about Magnetic resonance elastography.

Predicting 30-day mortality in patients with sepsis: an exploratory analysis of process of care and patient characteristics (2018)
Journal Article
Sanderson, M., Chikhani, M., Blyth, E., Wood, S., Moppett, I. K., McKeever, T., & Simmonds, M. J. (2018). Predicting 30-day mortality in patients with sepsis: an exploratory analysis of process of care and patient characteristics. Journal of the Intensive Care Society, 19(4), 299-304. https://doi.org/10.1177/1751143718758975

Background

Sepsis represents a significant public health burden, costing the NHS £2.5 billion annually, with 35% mortality in 2006. The aim of this exploratory study was to investigate risk factors predictive of 30-day mortality amongst patients w... Read More about Predicting 30-day mortality in patients with sepsis: an exploratory analysis of process of care and patient characteristics.

Multiple-therapy-resistant major depressive disorder: a clinically important concept (2018)
Journal Article
McAllistair-Williams, R., Christmas, D. M. B., Cleare, A. J., Currie, A., Gledhill, J., Insole, L., …Young, A. H. (2018). Multiple-therapy-resistant major depressive disorder: a clinically important concept. British Journal of Psychiatry, 212(5), 274-278. https://doi.org/10.1192/bjp.2017.33

Many novel therapeutic options for depression exist which are either not mentioned in clinical guidelines or recommended only for use in highly specialist services. The challenge faced by clinicians is when it might be appropriate to consider such ‘n... Read More about Multiple-therapy-resistant major depressive disorder: a clinically important concept.

Traits associated with central pain augmentation in the Knee Pain in the Community (KPIC) cohort (2018)
Journal Article
Akin-Akinyosoye, K., Frowd, N., Marshall, L., Stocks, J., Fernandes, G. S., Valdes, A. M., …Walsh, D. A. (2018). Traits associated with central pain augmentation in the Knee Pain in the Community (KPIC) cohort. PAIN, 159(6), 1035–1044. https://doi.org/10.1097/j.pain.0000000000001183

This study aimed to identify self-report correlates of central pain augmentation in individuals with knee pain. A subset of participants (n=420) in the Knee Pain and related health In the Community (KPIC) baseline survey undertook pressure pain thres... Read More about Traits associated with central pain augmentation in the Knee Pain in the Community (KPIC) cohort.

First international TNBC conference meeting report (2018)
Journal Article
Rida, P., Ogden, A., Ellis, I. O., Varga, Z., Wolff, A. C., Traina, T. A., …Aneja, R. (2018). First international TNBC conference meeting report. Breast Cancer Research and Treatment, 169(3), 407-412. https://doi.org/10.1007/s10549-018-4692-3

Recently, Georgia State University’s Centennial Hall was the premier location for the 2017 International Conference on Triple Negative Breast Cancer (TNBC): Illuminating Actionable Biology, which was held from Sept. 18 to 20, 2017, in Atlanta, USA. T... Read More about First international TNBC conference meeting report.

Exercise and other nonpharmacological strategies to reduce blood pressure in older adults: a systematic review and meta-analysis (2018)
Journal Article
Herrod, P. J., Doleman, B., Blackwell, J. E., O’Boyle, F., Williams, J. P., Lund, J. N., & Phillips, B. E. (in press). Exercise and other nonpharmacological strategies to reduce blood pressure in older adults: a systematic review and meta-analysis. Journal of the American Society of Hypertension, 12(4), https://doi.org/10.1016/j.jash.2018.01.008

The incidence of hypertension increases with advancing age and represents a significant burden of disease. Lifestyle modification represents the first-line intervention in treatment algorithms; however, the majority of evidence for this comes from st... Read More about Exercise and other nonpharmacological strategies to reduce blood pressure in older adults: a systematic review and meta-analysis.

Interventions to improve retention in a surgical, clinical trial: a pragmatic, stakeholder driven approach (2018)
Journal Article
Leighton, P., Brealey, S. D., & Dias, J. J. (in press). Interventions to improve retention in a surgical, clinical trial: a pragmatic, stakeholder driven approach. Journal of Evidence-Based Medicine, https://doi.org/10.1111/jebm.12271

Objective

To explore stakeholder perspectives upon participant retention in clinical trials, and to generate strategies to support retention in a surgical, clinical trial.

Study Design & Setting


The SWIFFT trial is a multi-centre study com... Read More about Interventions to improve retention in a surgical, clinical trial: a pragmatic, stakeholder driven approach.

Quantitative outcomes of a One Health approach to study global health challenges (2018)
Journal Article
Falzon, L. C., Lechner, I., Chantziaras, I., Collineau, L., Courcoul, A., Filippitzi, M.-E., …Brennan, M. L. (2018). Quantitative outcomes of a One Health approach to study global health challenges. EcoHealth, 15(1), 209-227. https://doi.org/10.1007/s10393-017-1310-5

Having gained momentum in the last decade, the One Health initiative promotes a holistic approach to address complex global health issues. Before recommending its adoption to stakeholders, however, it is paramount to first compile quantitative eviden... Read More about Quantitative outcomes of a One Health approach to study global health challenges.

Risk factors for eating disorder psychopathology within the treatment seeking transgender population: the role of cross-sex hormone treatment (2018)
Journal Article
Jones, B. A., Haycraft, E., Bouman, W. P., Brewin, N., Claes, L., & Arcelus, J. (2018). Risk factors for eating disorder psychopathology within the treatment seeking transgender population: the role of cross-sex hormone treatment. European Eating Disorders Review, 26(2), https://doi.org/10.1002/erv.2576

Many transgender people experience high levels of body dissatisfaction, which is one of numerous factors known to increase vulnerability to eating disorder symptoms in the cisgender (non-trans) population. Cross-sex hormones can alleviate body dissat... Read More about Risk factors for eating disorder psychopathology within the treatment seeking transgender population: the role of cross-sex hormone treatment.

Real-time estimation of horizontal gaze angle by saccade integration using in-ear electrooculography (2018)
Journal Article
Hládek, Ľ., Porr, B., & Brimijoin, W. O. (2018). Real-time estimation of horizontal gaze angle by saccade integration using in-ear electrooculography. PLoS ONE, 13(1), Article e0190420. https://doi.org/10.1371/journal.pone.0190420

The manuscript proposes and evaluates a real-time algorithm for estimating eye gaze angle based solely on single-channel electrooculography (EOG), which can be obtained directly from the ear canal using conductive ear moulds. In contrast to conventio... Read More about Real-time estimation of horizontal gaze angle by saccade integration using in-ear electrooculography.

Ethnicity and long-term course and outcome of psychotic disorders in a UK sample: the AESOP-10 study (2018)
Journal Article
Morgan, C., Fearon, P., Lappin, J. M., Heslin, M., Donoghue, K., Lomas, B., …Dazzan, P. (in press). Ethnicity and long-term course and outcome of psychotic disorders in a UK sample: the AESOP-10 study. British Journal of Psychiatry, 211(2), https://doi.org/10.1192/bjp.bp.116.193342

Background

The incidence of psychotic disorders is elevated in some minority ethnic populations. However, we know little about the outcome of psychoses in these populations.

Aim

To investigate patterns and determinants of long-term course an... Read More about Ethnicity and long-term course and outcome of psychotic disorders in a UK sample: the AESOP-10 study.

Diagnostic Criteria for Somatosensory Tinnitus: A Delphi Process and Face-to-Face Meeting to Establish Consensus (2018)
Journal Article
Michiels, S., Sanchez, T. G., Oron, Y., Gilles, A., Haider, H. F., Erlandsson, S., …Hall, D. A. (2018). Diagnostic Criteria for Somatosensory Tinnitus: A Delphi Process and Face-to-Face Meeting to Establish Consensus. Trends in Hearing, 22, 1-10. https://doi.org/10.1177/2331216518796403

Since somatic or somatosensory tinnitus (ST) was first described as a subtype of subjective tinnitus, where altered somatosensory afference from the cervical spine or temporomandibular area causes or changes a patient’s tinnitus perception, several s... Read More about Diagnostic Criteria for Somatosensory Tinnitus: A Delphi Process and Face-to-Face Meeting to Establish Consensus.

Oestrogen receptor negative early operable primary breast cancer in older women—biological characteristics and long-term clinical outcome (2017)
Journal Article
Syed, B. M., Morgan, D., Setty, T., Green, A. R., Paish, E. C., Ellis, I. O., & Cheung, K.-L. (2017). Oestrogen receptor negative early operable primary breast cancer in older women—biological characteristics and long-term clinical outcome. PLoS ONE, 12(12), Article e0188528. https://doi.org/10.1371/journal.pone.0188528

Background

Older women are at the greatest risk of breast cancer development and a considerable number present with comorbidities. Although the majority of breast cancers in this age group express oestrogen receptor (ER), which makes endocrine the... Read More about Oestrogen receptor negative early operable primary breast cancer in older women—biological characteristics and long-term clinical outcome.

Proportion of contextual effects in the treatment of fibromyalgia - a meta-analysis of randomised controlled trials (2017)
Journal Article
Whiteside, N., Sarmanova, A., Chen, X., Zou, K., Abdullah, N., Doherty, M., & Zhang, W. (in press). Proportion of contextual effects in the treatment of fibromyalgia - a meta-analysis of randomised controlled trials. Clinical Rheumatology, https://doi.org/10.1007/s10067-017-3948-3

Objectives: To examine the proportion of the total treatment effect that is attributable to contextual effects in randomised controlled trials (RCTs) of treatments for fibromyalgia.
Methods: A systematic literature search was undertaken in Medline,... Read More about Proportion of contextual effects in the treatment of fibromyalgia - a meta-analysis of randomised controlled trials.