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Application of the horse grimace scale in horses with dental disease: Preliminary findings (2024)
Journal Article
Sidwell, A. E., Duz, M., Hill, B., Freeman, S., & Hole, S. L. (2024). Application of the horse grimace scale in horses with dental disease: Preliminary findings. Veterinary Record, https://doi.org/10.1002/vetr.4800

Background

Dental disease is a common but often under-recognised condition in horses, possibly due to an inability to recognise clinical signs of oral discomfort. Some dental disorders are reportedly more painful than others, but there is no curre... Read More about Application of the horse grimace scale in horses with dental disease: Preliminary findings.

Metagenomic profiling of cecal microbiota and antibiotic resistome in rodents (2024)
Journal Article
Shang, K.-M., Elsheikha, H. M., Ma, H., Wei, Y.-J., Zhao, J.-X., Qin, Y., Li, J.-M., Zhao, Z.-Y., & Zhang, X.-X. (2024). Metagenomic profiling of cecal microbiota and antibiotic resistome in rodents. Ecotoxicology and Environmental Safety, 286, Article 117186. https://doi.org/10.1016/j.ecoenv.2024.117186

The rodent gut microbiota is a known reservoir of antimicrobial resistance, yet the distribution of antibiotic resistance genes (ARGs) within rodent cecal microbial communities and the specific bacterial species harboring these ARGs remain largely un... Read More about Metagenomic profiling of cecal microbiota and antibiotic resistome in rodents.

PIMMS-Dash: Accessible analysis, interrogation, and visualisation of high-throughput transposon insertion sequencing (TIS) data (2024)
Journal Article
Blanchard, A. M., Taylor, A., Warry, A., Shephard, F., Curwen, A., Leigh, J. A., Emes, R. D., & Egan, S. A. (2024). PIMMS-Dash: Accessible analysis, interrogation, and visualisation of high-throughput transposon insertion sequencing (TIS) data. Computational and Structural Biotechnology Journal, 23, 3780-3783. https://doi.org/10.1016/j.csbj.2024.10.025

Motivation: Current methods for visualising and interrogating high-throughput transposon insertion mutagenesis sequencing (TIS) data requires a significant time investment in learning bioinformatics, often producing static figures that do not facilit... Read More about PIMMS-Dash: Accessible analysis, interrogation, and visualisation of high-throughput transposon insertion sequencing (TIS) data.

Priming from within: TLR2 dependent but receptor independent activation of the mammary macrophage inflammasome by Streptococcus uberis (2024)
Journal Article
Hinds, A., Ward, P., Archer, N., & Leigh, J. (2024). Priming from within: TLR2 dependent but receptor independent activation of the mammary macrophage inflammasome by Streptococcus uberis. Frontiers in Cellular and Infection Microbiology, 14, Article 1444178. https://doi.org/10.3389/fcimb.2024.1444178

Introduction: Streptococcus uberis is a member of the pyogenic cluster of Streptococcus commonly associated with intramammary infection and mastitis in dairy cattle. It is a poorly controlled globally endemic pathogen responsible for a significant ca... Read More about Priming from within: TLR2 dependent but receptor independent activation of the mammary macrophage inflammasome by Streptococcus uberis.

A case of bovine erythropoietic protoporphyria in a female Limousin calf (2024)
Journal Article
CAPUZZELLO, G., Kaczmarska, A., Gutierrez Quintana, R., Jonsson, N. N., & Viora, L. (2024). A case of bovine erythropoietic protoporphyria in a female Limousin calf. Large Animal Review, 30(5), 223-226

Bovine erythropoietic protoporphyria (BCEPP) is a rare genetic disorder predominantly affecting Limousin and, sporadically, Blonde Aquitaine cattle. It arises from diminished or absent ferrochelatase activity, causing the toxic build up of protoporph... Read More about A case of bovine erythropoietic protoporphyria in a female Limousin calf.

Geometric characteristics of stromal collagen fibres in breast cancer using differential interference contrast microscopy (2024)
Journal Article
Ghannam, S. F., Rutland, C. S., Allegrucci, C., Mather, M. L., Alsaleem, M., Bateman‐Price, T. D., Patke, R., Ball, G., Mongan, N. P., & Rakha, E. (2024). Geometric characteristics of stromal collagen fibres in breast cancer using differential interference contrast microscopy. Journal of Microscopy, https://doi.org/10.1111/jmi.13361

Breast cancer (BC) is characterised by a high level of heterogeneity, which is influenced by the interaction of neoplastic cells with the tumour microenvironment. The diagnostic and prognostic role of the tumour stroma in BC remains to be defined. Di... Read More about Geometric characteristics of stromal collagen fibres in breast cancer using differential interference contrast microscopy.

The expanding role of cap-adjacent modifications in animals (2024)
Journal Article
Bellows, E., Fray, R. G., Knight, H. M., & Archer, N. (2024). The expanding role of cap-adjacent modifications in animals. Frontiers in RNA Research, 2, Article 1485307. https://doi.org/10.3389/frnar.2024.1485307

Eukaryotic mRNA cap structures directly influence mRNA stability, translation, and immune recognition. While the significance of the mRNA cap itself has been well-established, recent research has revealed the intricate modifications to the nucleotide... Read More about The expanding role of cap-adjacent modifications in animals.

Temporal Trends in Equine Sperm Motility and Semen Volume: A Retrospective Analysis from a Single UK Breeding Facility (2024)
Journal Article
Harris, I. T., Nankervis, K., Pyatt, A., Gardner, D. S., Humphreys, P., & Blanchard, R. N. (2024). Temporal Trends in Equine Sperm Motility and Semen Volume: A Retrospective Analysis from a Single UK Breeding Facility. International Journal of Equine Science, 3(2), 100-106

The equine industry preferentially selects sires based on pedigree, performance, and conformation, with little concern given to fertility. Increasing evidence supports the theory of geographic-sensitive declines in a range of semen quality parameters... Read More about Temporal Trends in Equine Sperm Motility and Semen Volume: A Retrospective Analysis from a Single UK Breeding Facility.

Isolation of phage-antibodies against Eimeria species that infect chickens (2024)
Journal Article
Angani, M. T., Owen, J. P., Maddison, B. C., & Gough, K. C. (2024). Isolation of phage-antibodies against Eimeria species that infect chickens. Journal of Immunological Methods, 534, Article 113759. https://doi.org/10.1016/j.jim.2024.113759

Eimeria is one of the most economically important pathogens in poultry production. Diagnosis of infection has the potential to inform treatment and prevention strategies. Here, phage display technology was used to isolate single chain antibodies (scF... Read More about Isolation of phage-antibodies against Eimeria species that infect chickens.

Possible sinoatrial node dysfunction in a 6-month-old domestic shorthair cat (2024)
Journal Article
Hillen, F., & Locquet, L. (in press). Possible sinoatrial node dysfunction in a 6-month-old domestic shorthair cat. Journal of Feline Medicine and Surgery Open Reports,

Case summary A six-month-old male entire domestic shorthair cat was presented to the ophthalmology department for nasolacrimal duct cannulation and flushing, and castration under general anaesthesia. On preanaesthetic assessment the cat had a heart r... Read More about Possible sinoatrial node dysfunction in a 6-month-old domestic shorthair cat.

Core and accessory genomic traits of Vibrio cholerae O1 drive lineage transmission and disease severity (2024)
Journal Article
Maciel-Guerra, A., Babaarslan, K., Baker, M., Rahman, A., Hossain, M., Sadique, A., Alam, J., Uzzaman, S., Ferdous, M., Ferdous Rahman Sarker, M., Sultana, N., Islam Khan, A. I., Begum, Y. A., Afrad, M. H., Senin, N., Habib, Z. H., Shirin, T., Qadri, F., & Dottorini, T. (2024). Core and accessory genomic traits of Vibrio cholerae O1 drive lineage transmission and disease severity. Nature Communications, 15(1), Article 8231. https://doi.org/10.1038/s41467-024-52238-0

In Bangladesh, Vibrio cholerae lineages are undergoing genomic evolution, with increased virulence and spreading ability. However, our understanding of the genomic determinants influencing lineage transmission and disease severity remains incomplete.... Read More about Core and accessory genomic traits of Vibrio cholerae O1 drive lineage transmission and disease severity.

Communication Skills Influence Horse Owners’ Trust in Their Equine Veterinarian (2024)
Journal Article
Rutherford, D. J., & England, J. .. (in press). Communication Skills Influence Horse Owners’ Trust in Their Equine Veterinarian. Veterinary Record,

Background: Trust is an essential component in the relationship between vets and horse owners.

Methods: Using an anonymous online survey, we asked if horse owners consider their vets to be credible, reliable, empathetic and self-orientated, and th... Read More about Communication Skills Influence Horse Owners’ Trust in Their Equine Veterinarian.

Investigative power of Genomic Informational Field Theory (GIFT) relative to GWAS for genotype-phenotype mapping. (2024)
Journal Article
Kyratzi, P., Matika, O., Brassington, A. H., Clare, C. E., Xu, J., Barrett, D. A., Emes, R. D., Archibald, A. L., Paldi, A., Sinclair, K. D., Wattis, J., & Rauch, C. (in press). Investigative power of Genomic Informational Field Theory (GIFT) relative to GWAS for genotype-phenotype mapping. Physiological Genomics, https://doi.org/10.1152/physiolgenomics.00049.2024

Identifying associations between phenotype and genotype is the fundamental basis of genetic analyses. Inspired by frequentist probability and the work of R.A. Fisher, genome-wide association studies (GWAS) extract information using averages and varia... Read More about Investigative power of Genomic Informational Field Theory (GIFT) relative to GWAS for genotype-phenotype mapping..

High prevalence and risk factors of feline leukemia virus infection in Chilean urban cats (Felis catus). (2024)
Journal Article
Castillo-Aliaga, C., Castro-Seriche, S., Jerez-Morales, A., & Tarlinton, R. (2024). High prevalence and risk factors of feline leukemia virus infection in Chilean urban cats (Felis catus). Research in Veterinary Science, 180, Article 105403. https://doi.org/10.1016/j.rvsc.2024.105403

Feline Leukemia Virus is a retrovirus causing fatal disease in domestic cats. While FeLV has been controlled in many countries, it remains a major concern in Latin American countries. This study conducted an epidemiological survey of FeLV in 182 Chil... Read More about High prevalence and risk factors of feline leukemia virus infection in Chilean urban cats (Felis catus)..

The Conflicting Prognostic Role of the Stroma–Tumor Ratio in Breast Cancer Molecular Subtypes (2024)
Journal Article
Ghannam, S. F., Makhlouf, S., Alsaleem, M., Rutland, C. S., Allegrucci, C., Mongan, N. P., & Rakha, E. (2024). The Conflicting Prognostic Role of the Stroma–Tumor Ratio in Breast Cancer Molecular Subtypes. Modern Pathology, 37(12), Article 100607. https://doi.org/10.1016/j.modpat.2024.100607

The tumor microenvironment plays a key role in tumor progression. The proportion of the stroma-to-tumor cells (stroma-tumor ratio [STR]) has a variable prognostic significance in breast cancer (BC) molecular classes. In this study, we evaluated the m... Read More about The Conflicting Prognostic Role of the Stroma–Tumor Ratio in Breast Cancer Molecular Subtypes.

Effects of weaning‐related stress on the emotional health of horses—A scoping review (2024)
Journal Article
Dwyer, J., L. Roshier, A., Campbell, M., Hill, B., & L. Freeman, S. (2024). Effects of weaning‐related stress on the emotional health of horses—A scoping review. Equine Veterinary Journal, https://doi.org/10.1111/evj.14412

Background
Weaning represents one of the most stressful events in the life of a horse, and may have long-term impacts on behaviour. There are a range of approaches used to wean foals from mares, including abrupt and progressive separation methods. T... Read More about Effects of weaning‐related stress on the emotional health of horses—A scoping review.