All Outputs (1461)

Development of Virus-like Particle Plant-Based Vaccines against Avian H5 and H9 Influenza A Viruses (2024)
Journal Article
Elbohy, O. A., Iqbal, M., Daly, J. M., & Dunham, S. P. (2024). Development of Virus-like Particle Plant-Based Vaccines against Avian H5 and H9 Influenza A Viruses. Veterinary Sciences, 11(2), Article 93. https://doi.org/10.3390/vetsci11020093

Avian influenza A virus (AIV) is a significant cause of mortality in poultry, causing substantial economic loss, particularly in developing countries, and has zoonotic potential. For example, highly pathogenic avian influenza (HPAI) viruses of the H5... Read More about Development of Virus-like Particle Plant-Based Vaccines against Avian H5 and H9 Influenza A Viruses.

Repeat patient testing-quality control compared to commercial quality control material for the Sysmex XT-2000iV hematology analyzer in a multi-site veterinary laboratory (2024)
Journal Article
Daly, S., Rishniw, M., Graham, P. A., & Freeman, K. P. (2024). Repeat patient testing-quality control compared to commercial quality control material for the Sysmex XT-2000iV hematology analyzer in a multi-site veterinary laboratory. Veterinary Clinical Pathology, 53(S1), 48-59. https://doi.org/10.1111/vcp.13332

Background: Quality control material (QCM) for hematology in veterinary laboratories is limited, and repeat patient testing quality control (RPT‐QC) is an alternative method using excess matrix‐specific samples. Objectives: This study aimed to determ... Read More about Repeat patient testing-quality control compared to commercial quality control material for the Sysmex XT-2000iV hematology analyzer in a multi-site veterinary laboratory.

Quantification of the effect of in utero events on lifetime resilience in dairy cows (2024)
Journal Article
Lewis, K., Shewbridge Carter, L., Bradley, A., Dewhurst, R., Forde, N., Hyde, R., …Green, M. (2024). Quantification of the effect of in utero events on lifetime resilience in dairy cows. Journal of Dairy Science, 107(7), 4616-4633. https://doi.org/10.3168/jds.2023-24215

Currently, the dairy industry is facing many challenges that could affect its sustainability, including climate change and public perception of the industry. As a result, interest is increasing in the concept of identifying resilient animals, those w... Read More about Quantification of the effect of in utero events on lifetime resilience in dairy cows.

Lack of detection of SARS-CoV-2 in wildlife from Kerala, India in 2020–21 (2024)
Journal Article
Zachariah, A., Krishnankutty, S. P., Manazhi, J., Omanakuttan, V., Santosh, S., Blanchard, A., & Tarlinton, R. (2024). Lack of detection of SARS-CoV-2 in wildlife from Kerala, India in 2020–21. Access Microbiology, 6(1), Article 000686. https://doi.org/10.1099/acmi.0.000686.v3

Spillover of SARS-CoV-2 into a variety of wild and domestic animals has been an ongoing feature of the human pandemic. The establishment of a new reservoir in white-tailed deer in North America and increasing divergence of the viruses circulating in... Read More about Lack of detection of SARS-CoV-2 in wildlife from Kerala, India in 2020–21.

Novel enrichment reduces boredom-associated behaviors in housed dairy cows (2024)
Journal Article
Russell, A. L., Randall, L. V., Eyre, N., Kaler, J., & Green, M. J. (2024). Novel enrichment reduces boredom-associated behaviors in housed dairy cows. JDS Communications, 5(5), 452-456. https://doi.org/10.3168/jdsc.2023-0475

There is currently societal interest and concern for dairy cow welfare. It has been suggested that boredom poses a welfare issue for dairy cows, particularly when presented with extended disposable time in housed environments that lack stimuli. Farm... Read More about Novel enrichment reduces boredom-associated behaviors in housed dairy cows.

The transcription factor AP2XI-2 is a key negative regulator of Toxoplasma gondii merogony (2024)
Journal Article
Wang, J., Li, T., Zhang, N., Wang, M., Sun, L., Zhang, Z., …Zhu, X. (2024). The transcription factor AP2XI-2 is a key negative regulator of Toxoplasma gondii merogony. Nature Communications, 15(1), Article 793. https://doi.org/10.1038/s41467-024-44967-z

Sexual development in Toxoplasma gondii is a multistep process that culminates in the production of oocysts, constituting approximately 50% of human infections. However, the molecular mechanisms governing sexual commitment in this parasite remain poo... Read More about The transcription factor AP2XI-2 is a key negative regulator of Toxoplasma gondii merogony.

Student Co-creation of Digital Learning Resources: An evaluation and reflection of veterinary pharmacy and care home pharmacy interprofessional education packages (2024)
Journal Article
Chandarana, P., Rickaby, R., Sonnex, K., Allegrucci, C., & Garcia-Ara, A. (2024). Student Co-creation of Digital Learning Resources: An evaluation and reflection of veterinary pharmacy and care home pharmacy interprofessional education packages. Student Engagement in Higher Education Journal, 5(2), 203-227

Funding secured from the University of Nottingham was used to enable students to work together with academics to develop two interprofessional education (IPE) e-learning resources using XerteTM. One project focussed on veterinary pharmacy and involve... Read More about Student Co-creation of Digital Learning Resources: An evaluation and reflection of veterinary pharmacy and care home pharmacy interprofessional education packages.

Combined biolistic and cell penetrating peptide delivery for the development of scalable intradermal DNA vaccines (2024)
Journal Article
So, R. B., Li, G., Brentville, V., Daly, J. M., & Dixon, J. E. (2024). Combined biolistic and cell penetrating peptide delivery for the development of scalable intradermal DNA vaccines. Journal of Controlled Release, 367, 209-222. https://doi.org/10.1016/j.jconrel.2024.01.031

Physical-based gene delivery via biolistic methods (such as the Helios gene gun) involve precipitation of nucleic acids onto microparticles and direct transfection through cell membranes of exposed tissue (e.g. skin) by high velocity acceleration. Th... Read More about Combined biolistic and cell penetrating peptide delivery for the development of scalable intradermal DNA vaccines.

Changes in Immune Response during Pig Gestation with a Focus on Cytokines (2024)
Journal Article
Velez, C., Williamson, D., Lorena Cánovas, M., Romina Giai, L., Rutland, C., Pérez, W., & Barbeito, C. G. (2024). Changes in Immune Response during Pig Gestation with a Focus on Cytokines. Veterinary Sciences, 11(1), Article 50. https://doi.org/10.3390/vetsci11010050

Pigs have the highest percentage of embryonic death not associated with specific diseases of all livestock species, at 20–45%. During gestation processes, a series of complex alterations can arise, including embryonic migration and elongation, matern... Read More about Changes in Immune Response during Pig Gestation with a Focus on Cytokines.

UK flockdown: A survey of smallscale poultry keepers and their understanding of governmental guidance on highly pathogenic avian influenza (HPAI) (2024)
Journal Article
McClaughlin, E., Elliott, S., Jewitt, S., Smallman-Raynor, M., Dunham, S., Parnell, T., …Tarlinton, R. (2024). UK flockdown: A survey of smallscale poultry keepers and their understanding of governmental guidance on highly pathogenic avian influenza (HPAI). Preventive Veterinary Medicine, 224, Article 106117. https://doi.org/10.1016/j.prevetmed.2024.106117

The scale of the current outbreak of highly pathogenic avian influenza (HPAI) due to the A/H5N1 virus in the United Kingdom is unprecedented. In addition to its economic impact on the commercial poultry sector, the disease has devastated wild bird co... Read More about UK flockdown: A survey of smallscale poultry keepers and their understanding of governmental guidance on highly pathogenic avian influenza (HPAI).

Veterinarians’ knowledge and experience of avian influenza and perspectives on control measures in the UK (2024)
Journal Article
Jewitt, S., McClaughlin, E., Elliott, S., Smallman-Raynor, M., Clark, M., Dunham, S., & Tarlinton, R. (2024). Veterinarians’ knowledge and experience of avian influenza and perspectives on control measures in the UK. Veterinary Record, 195(5), Article e3713. https://doi.org/10.1002/vetr.3713

Background
The scale of the outbreak of highly pathogenic avian influenza (HPAI) in 2021–23 due to the influenza A/H5N1 virus is unprecedented.

Methods
An online survey was designed to explore veterinarians’ experiences of and confidence in trea... Read More about Veterinarians’ knowledge and experience of avian influenza and perspectives on control measures in the UK.

Veterinarians' knowledge and experience of avian influenza and perspectives on control measures in the United Kingdom (2024)
Journal Article
Jewitt, S., Mcclaughlin, E., Elliott, S., Smallman-Raynor, M., Clark, M., Dunham, S., & Tarlinton, R. (2024). Veterinarians' knowledge and experience of avian influenza and perspectives on control measures in the United Kingdom. Veterinary Record, 195(5), Article e3713. https://doi.org/10.1002/vetr.3713

Background
The scale of the outbreak of highly pathogenic avian influenza (HPAI) in 2021–23 due to the influenza A/H5N1 virus is unprecedented.

Methods
An online survey was designed to explore veterinarians’ experiences of and confidence in trea... Read More about Veterinarians' knowledge and experience of avian influenza and perspectives on control measures in the United Kingdom.

Convergence of resistance and evolutionary responses in Escherichia coli and Salmonella enterica co-inhabiting chicken farms in China (2024)
Journal Article
Baker, M., Zhang, X., Maciel-Guerra, A., Babaarslan, K., Dong, Y., Wang, W., …Dottorini, T. (2024). Convergence of resistance and evolutionary responses in Escherichia coli and Salmonella enterica co-inhabiting chicken farms in China. Nature Communications, 15, Article 206. https://doi.org/10.1038/s41467-023-44272-1

Sharing of genetic elements among different pathogens and commensals inhabiting same hosts and environments has significant implications for antimicrobial resistance (AMR), especially in settings with high antimicrobial exposure. We analysed 661 Esch... Read More about Convergence of resistance and evolutionary responses in Escherichia coli and Salmonella enterica co-inhabiting chicken farms in China.

Global prevalence of Plasmodium infection in wild birds: A systematic review and meta-analysis (2024)
Journal Article
Yan, W. L., Sun, H. T., Zhao, Y. C., Hou, X. W., Zhang, M., Zhao, Q., …Ni, H. B. (2024). Global prevalence of Plasmodium infection in wild birds: A systematic review and meta-analysis. Research in Veterinary Science, 168, Article 105136. https://doi.org/10.1016/j.rvsc.2024.105136

Avian malaria is a vector-borne parasitic disease caused by Plasmodium infection transmitted to birds by mosquitoes. The aim of this systematic review was to analyze the global prevalence of malaria and risk factors associated with infection in wild... Read More about Global prevalence of Plasmodium infection in wild birds: A systematic review and meta-analysis.

A Functional Single-Nucleotide Polymorphism Upstream of the Collagen Type III Gene Is Associated with Catastrophic Fracture Risk in Thoroughbred Horses (2023)
Journal Article
Palomino Lago, E., Baird, A., Blott, S. C., McPhail, R. E., Ross, A. C., Durward-Akhurst, S. A., & Guest, D. J. (2024). A Functional Single-Nucleotide Polymorphism Upstream of the Collagen Type III Gene Is Associated with Catastrophic Fracture Risk in Thoroughbred Horses. Animals, 14(1), Article 116. https://doi.org/10.3390/ani14010116

Fractures caused by bone overloading are a leading cause of euthanasia in Thoroughbred racehorses. The risk of fatal fracture has been shown to be influenced by both environmental and genetic factors but, to date, no specific genetic mechanisms under... Read More about A Functional Single-Nucleotide Polymorphism Upstream of the Collagen Type III Gene Is Associated with Catastrophic Fracture Risk in Thoroughbred Horses.

The Toxoplasma protein phosphatase 6 catalytic subunit (TgPP6C) is essential for cell cycle progression and virulence (2023)
Journal Article
Liang, Q. L., Nie, L. B., Elsheikha, H. M., Li, T. T., Sun, L. X., Zhang, Z. W., …Wang, J. L. (2023). The Toxoplasma protein phosphatase 6 catalytic subunit (TgPP6C) is essential for cell cycle progression and virulence. PLoS Pathogens, 19(12), Article e1011831. https://doi.org/10.1371/journal.ppat.1011831

Protein phosphatases are post-translational regulators of Toxoplasma gondii proliferation, tachyzoite-bradyzoite differentiation and pathogenesis. Here, we identify the putative protein phosphatase 6 (TgPP6) subunits of T. gondii and elucidate their... Read More about The Toxoplasma protein phosphatase 6 catalytic subunit (TgPP6C) is essential for cell cycle progression and virulence.

Improvement of mammary gland health in 81 'sentinel herds' in England and Scotland between 2012 and 2021. (2023)
Journal Article
Leach, K. A., Holsey, H. J., Bradley, A. J., & Green, M. J. (2023). Improvement of mammary gland health in 81 'sentinel herds' in England and Scotland between 2012 and 2021. Veterinary Record, Article e3605. https://doi.org/10.1002/vetr.3605

Background: Achieving a reduction in mastitis in dairy cows is a common industry goal, but there is no recent peer-reviewed record of progress in the UK. Methods: A convenience sample of 125 herds in England and Scotland was recruited based on the qu... Read More about Improvement of mammary gland health in 81 'sentinel herds' in England and Scotland between 2012 and 2021..

The splicing factor SR2 is an important virulence factor of Toxoplasma gondii (2023)
Journal Article
Wu, X., Nanzheng, X., Elsheikha, H. M., Li, T., Kou, Y., & Zhu, X. (2023). The splicing factor SR2 is an important virulence factor of Toxoplasma gondii. Frontiers in Microbiology, 14, Article 1302512. https://doi.org/10.3389/fmicb.2023.1302512

Serine/arginine-rich (SR) proteins are key factors with important roles in constitutive and alternative splicing (AS) of pre-mRNAs. However, the role of SR splicing factors in the pathogenicity of T. gondii remains largely unexplored. Here, we invest... Read More about The splicing factor SR2 is an important virulence factor of Toxoplasma gondii.

Prospective case study of critical decision making for horses referred for treatment of colic (2023)
Journal Article
Burrell, K., Sutton‐Walker, G., England, G. C. W., Burford, J. H., & Freeman, S. L. (2023). Prospective case study of critical decision making for horses referred for treatment of colic. Veterinary Record, 194(12), Article e3615. https://doi.org/10.1002/vetr.3615

Background
There is limited evidence on factors affecting critical decision making for horses with colic. This study's aim was to describe the assessment and decision making involved in horses referred for management of colic.

Methods
An in-dept... Read More about Prospective case study of critical decision making for horses referred for treatment of colic.

Incorporating biodiversity responses to land use change scenarios for preventing emerging zoonotic diseases in areas of unknown host-pathogen interactions (2023)
Journal Article
Roque, F. D. O., Bellón, B., Guerra, A., Valente-Neto, F., Santos, C. C., Melo, I., …Ochoa-Quintero, J. M. (2023). Incorporating biodiversity responses to land use change scenarios for preventing emerging zoonotic diseases in areas of unknown host-pathogen interactions. Frontiers in Veterinary Science, 10, Article 1229676. https://doi.org/10.3389/fvets.2023.1229676

The need to reconcile food production, the safeguarding of nature, and the protection of public health is imperative in a world of continuing global change, particularly in the context of risks of emerging zoonotic disease (EZD). In this paper, we ex... Read More about Incorporating biodiversity responses to land use change scenarios for preventing emerging zoonotic diseases in areas of unknown host-pathogen interactions.