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Agouti-related protein has an inhibitory paracrine role in the rat adrenal gland (2003)
Journal Article
Dhillo, W. S., Small, C. J., Gardiner, J. V., Bewick, G. A., Whitworth, E. J., Jethwa, P. H., …Bloom, S. R. (2003). Agouti-related protein has an inhibitory paracrine role in the rat adrenal gland. Biochemical and Biophysical Research Communications, 301(1), 102-107. https://doi.org/10.1016/S0006-291X%2802%2902991-1

α-Melanocyte-stimulating-hormone (α-MSH) is an agonist at the melanocortin 3 receptor (MC3-R) and melanocortin 4 receptor (MC4-R). α-MSH stimulates corticosterone release from rat adrenal glomerulosa cells in vitro. Agouti-related protein (AgRP) an e... Read More about Agouti-related protein has an inhibitory paracrine role in the rat adrenal gland.

Understanding relaxin in the female reproductive system (2002)
Journal Article
Ivell, R., & Anand-Ivell, R. (2003). Understanding relaxin in the female reproductive system. Current Medicinal Chemistry Immunology Endocrine and Metabolic Agents, 5(5), 383-389. https://doi.org/10.2174/156801305774322394

Recent advances in our understanding of the hormone relaxin, and the discovery of its specific receptor LGR7, have provided a series of new tools and paradigms, with which to re-examine many aspects of female reproductive physiology classically assoc... Read More about Understanding relaxin in the female reproductive system.

Hypothalamic Actions of Neuromedin U (2002)
Journal Article
Wren, A. M., Small, C. J., Abbott, C. R., Jethwa, P. H., Kennedy, A. R., Murphy, K. G., …Bloom, S. R. (2002). Hypothalamic Actions of Neuromedin U. Endocrinology, 143(11), 4227-4234. https://doi.org/10.1210/en.2002-220308

The central nervous system and gut peptide neuromedin U (NMU) inhibits feeding after intracerebroventricular injection. This study explored the hypothalamic actions of NMU on feeding and the hypothalamo-pituitary-adrenal axis. Intraparaventricular nu... Read More about Hypothalamic Actions of Neuromedin U.

Hypothalamic Interactions Between Neuropeptide Y, Agouti-Related Protein, Cocaine- and Amphetamine-Regulated Transcript and Alpha-Melanocyte-Stimulating Hormone In Vitro in Male Rats (2002)
Journal Article
Dhillo, W. S., Small, C. J., Stanley, S. A., Jethwa, P. H., Seal, L. J., Murphy, K. G., …Bloom, S. R. (2002). Hypothalamic Interactions Between Neuropeptide Y, Agouti-Related Protein, Cocaine- and Amphetamine-Regulated Transcript and Alpha-Melanocyte-Stimulating Hormone In Vitro in Male Rats. Journal of Neuroendocrinology, 14(9), 725-730. https://doi.org/10.1046/j.1365-2826.2002.00832.x

A number of neuropeptides implicated in the hypothalamic regulation of appetite are synthesized in the arcuate nucleus (Arc). Neuropeptide Y (NPY) and agouti-related protein (Agrp) are orexigenic. The pro-opiomelanocortin (POMC) product alpha-melanoc... Read More about Hypothalamic Interactions Between Neuropeptide Y, Agouti-Related Protein, Cocaine- and Amphetamine-Regulated Transcript and Alpha-Melanocyte-Stimulating Hormone In Vitro in Male Rats.

Predicting arsenic solubility in contaminated soils using isotopic dilution techniques (2002)
Journal Article
Tye, A. M., Young, S. D., Crout, N. M., Zhang, H., Preston, S., Bailey, E. H., …Kilham, K. (2002). Predicting arsenic solubility in contaminated soils using isotopic dilution techniques. Environmental Science and Technology, 36(5), 982-988. https://doi.org/10.1021/es0101633

An isotopic dilution assay was developed to measure radiolabile As concentration in a diverse range of soils (pH 3.30-7.62; % C = 1.00-6.55). Soils amended with 50 mg of As kg-1 (as Na2HAsO4·7H2O) were incubated for over 800 d in an aerated "microcos... Read More about Predicting arsenic solubility in contaminated soils using isotopic dilution techniques.

Maternal nutrient restriction during early to mid gestation alters the relationship between insulin-like growth factor I and bodyweight at term in fetal sheep (2000)
Journal Article
Heasman, L., Brameld, J., Mostyn, A., Budge, H., Dawson, J., Buttery, P., …Symonds, M. E. (2000). Maternal nutrient restriction during early to mid gestation alters the relationship between insulin-like growth factor I and bodyweight at term in fetal sheep. Reproduction, Fertility and Development, 12(7-8), 345-350. https://doi.org/10.1071/RD00115

The present study was designed to determine whether altered placental size, as a consequence of maternal nutrient restriction in sheep between 28 and 77 days gestation, is associated with a modified relationship between fetal weight or dimensions and... Read More about Maternal nutrient restriction during early to mid gestation alters the relationship between insulin-like growth factor I and bodyweight at term in fetal sheep.

Maternal nutrition alters the expression of insulin-like growth factors in fetal sheep liver and skeletal muscle (2000)
Journal Article
Brameld, J. M., Mostyn, A., Dandrea, J., Stephenson, T. J., Dawson, J. M., Buttery, P. J., & Symonds, M. E. (2000). Maternal nutrition alters the expression of insulin-like growth factors in fetal sheep liver and skeletal muscle. Journal of Endocrinology, 167(3), 429-437. https://doi.org/10.1677/joe.0.1670429

We investigated the influence of maternal dietary restriction between days 28 and 80 of gestation followed by re-feeding to the intake of well-fed ewes up to 140 days of gestation (term is 147 days) in sheep, on expression of mRNA for insulin-like gr... Read More about Maternal nutrition alters the expression of insulin-like growth factors in fetal sheep liver and skeletal muscle.

Maternal nutrient restriction during early to mid gestation alters the relationship between insulin-like growth factor I and bodyweight at term in fetal sheep (2000)
Journal Article
Heasman, L., Brameld, J., Mostyn, A., Budge, H., Dawson, J., Buttery, P., …Symonds, M. E. (2000). Maternal nutrient restriction during early to mid gestation alters the relationship between insulin-like growth factor I and bodyweight at term in fetal sheep. Reproduction, Fertility and Development, 12(7-8), 345-350. https://doi.org/10.1071/rd00115

The present study was designed to determine whether altered placental size, as a consequence of maternal nutrient restriction in sheep between 28 and 77 days gestation, is associated with a modified relationship between fetal weight or dimensions and... Read More about Maternal nutrient restriction during early to mid gestation alters the relationship between insulin-like growth factor I and bodyweight at term in fetal sheep.

Glucose and amino acids interact with hormones to control expression of insulin-like growth factor-I and growth hormone receptor mRNA in cultured pig hepatocytes (1999)
Journal Article
Brameld, J. M., Gilmour, R. S., & Buttery, P. J. (1999). Glucose and amino acids interact with hormones to control expression of insulin-like growth factor-I and growth hormone receptor mRNA in cultured pig hepatocytes. Journal of Nutrition, 129(7), 1298-1306. https://doi.org/10.1093/jn/129.7.1298

Nutrients and hormones are major determinants of animal growth, but the mechanisms of how nutrients influence the growth process are still unclear. A primary pig hepatocyte culture system was used to investigate possible direct effects of glucose and... Read More about Glucose and amino acids interact with hormones to control expression of insulin-like growth factor-I and growth hormone receptor mRNA in cultured pig hepatocytes.

Glucose and amino acids interact with hormones to control expression of insulin-like growth factor-I and growth hormone receptor mRNA in cultured pig hepatocytes (1999)
Journal Article
Brameld, J. M., Gilmour, R. S., & Buttery, P. J. (1999). Glucose and amino acids interact with hormones to control expression of insulin-like growth factor-I and growth hormone receptor mRNA in cultured pig hepatocytes. Journal of Nutrition, 129(7), 1298-1306. https://doi.org/10.1093/jn/129.7.1298

Nutrients and hormones are major determinants of animal growth, but the mechanisms of how nutrients influence the growth process are still unclear. A primary pig hepatocyte culture system was used to investigate possible direct effects of glucose and... Read More about Glucose and amino acids interact with hormones to control expression of insulin-like growth factor-I and growth hormone receptor mRNA in cultured pig hepatocytes.

Effects of growth hormone administration and dietary protein intake on insulin-like growth factor I and growth hormone receptor mRNA Expression in porcine liver, skeletal muscle, and adipose tissue (1996)
Journal Article
Brameld, J. M., Atkinson, J. L., Saunders, J. C., Pell, J. M., Buttery, P. J., & Gilmour, R. S. (1996). Effects of growth hormone administration and dietary protein intake on insulin-like growth factor I and growth hormone receptor mRNA Expression in porcine liver, skeletal muscle, and adipose tissue. Journal of Animal Science, 74(8), 1832-1841. https://doi.org/10.2527/1996.7481832x

The effects of growth hormone (GH) and dietary protein on expression of IGF-I and GH receptor (GHR) genes in liver, muscle, and fat of pigs were investigated. Forty-eight intact male Large White x Landrace pigs were allotted to eight treatment groups... Read More about Effects of growth hormone administration and dietary protein intake on insulin-like growth factor I and growth hormone receptor mRNA Expression in porcine liver, skeletal muscle, and adipose tissue.

Expression of insulin-like growth factor-1 (IGF-1) and growth hormone-receptor (GHR) mRNA in liver, skeletal muscle and adipose tissue of different breeds of pig (1996)
Journal Article
Brameld, J. M., Atkinson, J. L., Budd, T. J., Saunders, J. C., Pell, J. M., Salter, A. M., …Buttery, P. J. (1996). Expression of insulin-like growth factor-1 (IGF-1) and growth hormone-receptor (GHR) mRNA in liver, skeletal muscle and adipose tissue of different breeds of pig. Animal Science, 62(3), 555-559. https://doi.org/10.1017/S1357729800015101

The work described was carried out to study the expression of insulin-like growth factor 1 (IGF-1) and growth hormone-receptor (GHR) mRNA in liver, skeletal muscle and adipose tissue from three breeds of pig with varying growth characteristics. The t... Read More about Expression of insulin-like growth factor-1 (IGF-1) and growth hormone-receptor (GHR) mRNA in liver, skeletal muscle and adipose tissue of different breeds of pig.

Ontogenic study of insulin-like growth factor-1 and growth hormone receptor mRNA expression in porcine liver and skeletal muscle (1995)
Journal Article
Brameld, J. M., Weller, P. A., Pell, J. M., Buttery, P. J., & Gilmour, R. S. (1995). Ontogenic study of insulin-like growth factor-1 and growth hormone receptor mRNA expression in porcine liver and skeletal muscle. Animal Science, 61(2), 333-339. https://doi.org/10.1017/S1357729800013886

The growth hormone-insulin-like growth factor (GH-IGF) axis is involved in the control of postnatal growth in all animals studied to date. At birth, blood levels of IGF-1 are low, although levels of GH are high. Thus a switching occurs during the pos... Read More about Ontogenic study of insulin-like growth factor-1 and growth hormone receptor mRNA expression in porcine liver and skeletal muscle.

Hormonal control of insulin-like growth factor-I and growth hormone receptor mRNA expression by porcine hepatocytes in culture (1995)
Journal Article
Brameld, J. M., Weller, P. A., Saunders, J. C., Buttery, P. J., & Gilmour, R. S. (1995). Hormonal control of insulin-like growth factor-I and growth hormone receptor mRNA expression by porcine hepatocytes in culture. Journal of Endocrinology, 146(2), 239-245. https://doi.org/10.1677/joe.0.1460239

The effects of various hormones commonly added to hepatocyte culture media upon the expression of the GH receptor (GHR) and insulin-like growth factor-I (IGF-I) genes in cultured porcine hepatocytes were investigated. Preliminary investigations indic... Read More about Hormonal control of insulin-like growth factor-I and growth hormone receptor mRNA expression by porcine hepatocytes in culture.

Regulation of porcine insulin-like growth factor I and growth hormone receptor mRNA expression by energy status (1994)
Journal Article
Weller, P. A., Dauncey, M. J., Bates, P. C., Brameld, J. M., Buttery, P. J., & Gilmour, R. S. (1994). Regulation of porcine insulin-like growth factor I and growth hormone receptor mRNA expression by energy status. AJP - Endocrinology and Metabolism, 266(5), E776-E785. https://doi.org/10.1152/ajpendo.1994.266.5.E776

Regulation of insulin-like growth factor I (IGF-I) and growth hormone (GH) receptor mRNA in liver and muscle by energy status was assessed in 2-mo-old pigs by altering thermoregulatory demand and energy intake over a 5-wk period to produce a range of... Read More about Regulation of porcine insulin-like growth factor I and growth hormone receptor mRNA expression by energy status.

The renin-angiotensin system of the ovary (1991)
Journal Article
Brameld, J. M., & Broughton Pipkin, F. (1991). The renin-angiotensin system of the ovary. Contemporary Reviews in Obstetrics and Gynaecology, 3(2), 85-92

Studies on the human ovarian renin-angiotensin system: Optimization of assay methodology and effects of follicular stimulants (1990)
Journal Article
Brameld, J. M., Broughton Pipkin, F., & Symonds, E. M. (1990). Studies on the human ovarian renin-angiotensin system: Optimization of assay methodology and effects of follicular stimulants. Journal of Endocrinology, 127(3), 513-521. https://doi.org/10.1677/joe.0.1270513

The renal and genital tracts share common embryological origin; it is thus not surprising that tissues from both can synthesize renin. Preliminary studies showed extremely hgih concentrations of renin in follicular fluid (FRC) following ovarian stimu... Read More about Studies on the human ovarian renin-angiotensin system: Optimization of assay methodology and effects of follicular stimulants.