Design, synthesis and biological evaluation of vinyl selenone derivatives as novel microtubule polymerization inhibitors
(2020)
Journal Article
A series of novel vinyl selenone derivatives were designed, synthesized and evaluated as the tubulin polymerization inhibitors using a bioisosteric strategy. Among them, the representative compound 11k exhibited satisfactory anti-proliferative activi... Read More about Design, synthesis and biological evaluation of vinyl selenone derivatives as novel microtubule polymerization inhibitors.