All Outputs (2)

Signaling dynamics in coexisting monoclonal cell subpopulations unveil mechanisms of resistance to anti-cancer compounds (2024)
Journal Article
Blanchard, C. E., Gomeiz, A. T., Avery, K., Gazzah, E. E., Alsubaie, A. M., Sikaroodi, M., Chiari, Y., Ward, C., Sanchez, J., Espina, V., Petricoin, E., Baldelli, E., & Pierobon, M. (2024). Signaling dynamics in coexisting monoclonal cell subpopulations unveil mechanisms of resistance to anti-cancer compounds. Cell Communication and Signaling, 22(1), Article 377. https://doi.org/10.1186/s12964-024-01742-3

Background: Tumor heterogeneity is a main contributor of resistance to anti-cancer targeted agents though it has proven difficult to study. Unfortunately, model systems to functionally characterize and mechanistically study dynamic responses to treat... Read More about Signaling dynamics in coexisting monoclonal cell subpopulations unveil mechanisms of resistance to anti-cancer compounds.

Thermal tolerance plasticity and dynamics of thermal tolerance in Eublepharis macularius: Implications for future climate-driven heat stress (2024)
Journal Article
White, E., Kim, S., Wegh, G., & Chiari, Y. (2024). Thermal tolerance plasticity and dynamics of thermal tolerance in Eublepharis macularius: Implications for future climate-driven heat stress. Journal of Thermal Biology, 123, Article 103912. https://doi.org/10.1016/j.jtherbio.2024.103912

The intensity and duration of heat waves, as well as average global temperatures, are expected to increase due to climate change. Heat waves can cause physiological stress and reduce fitness in animals. Species can reduce overheating risk through phe... Read More about Thermal tolerance plasticity and dynamics of thermal tolerance in Eublepharis macularius: Implications for future climate-driven heat stress.