All Outputs (4)

Comparative effectiveness of different placebos and comparator groups for hand osteoarthritis exploring the impact of contextual factors: A systematic review and meta-analysis of randomised trials (2024)
Journal Article
Balsby, I. M., Nielsen, S. M., Christensen, R., Henriksen, M., Dahl, L. U.-M., Berg, J. I., …Døssing, A. (2024). Comparative effectiveness of different placebos and comparator groups for hand osteoarthritis exploring the impact of contextual factors: A systematic review and meta-analysis of randomised trials. Osteoarthritis and Cartilage, 32(7), 848-857. https://doi.org/10.1016/j.joca.2024.02.947

Objective: To examine the pain relief effects of comparators (placebos and untreated control groups) in hand osteoarthritis trials and the impact of contextual factors. Methods: We systematically searched PubMed, EMBASE and CENTRAL from inception to... Read More about Comparative effectiveness of different placebos and comparator groups for hand osteoarthritis exploring the impact of contextual factors: A systematic review and meta-analysis of randomised trials.

Serum levels of hydroxylated metabolites of arachidonic acid cross-sectionally and longitudinally predict knee pain progression: an observational cohort study (2024)
Journal Article
Turnbull, J., Jha, R. R., Gowler, P. R., Ferrands-Bentley, R., Kim, D.-H., Barrett, D. A., Sarmanova, A., Fernandes, G. S., Doherty, M., Zhang, W., Walsh, D. A., Valdes, A. M., & Chapman, V. (2024). Serum levels of hydroxylated metabolites of arachidonic acid cross-sectionally and longitudinally predict knee pain progression: an observational cohort study. Osteoarthritis and Cartilage, 32(8), 990-1000. https://doi.org/10.1016/j.joca.2024.04.006

Objective: To examine associations between serum oxylipins, which regulate tissue repair and pain signalling, and knee pain/radiographic osteoarthritis (OA) at baseline and knee pain at 3 year follow-up. Method: Baseline, and 3 year follow-up, kne... Read More about Serum levels of hydroxylated metabolites of arachidonic acid cross-sectionally and longitudinally predict knee pain progression: an observational cohort study.

Association Between Hyperuricemia and Ultrasound-Detected Hand Synovitis (2024)
Journal Article
Jiang, T., Weng, Q., Zhang, Y., Zhang, W., Doherty, M., Sarmanova, A., Yang, Z., Yang, T., Li, J., Liu, K., Wang, Y., Obotiba, A. D., Zeng, C., Lei, G., & Wei, J. (2024). Association Between Hyperuricemia and Ultrasound-Detected Hand Synovitis. Arthritis Care and Research, https://doi.org/10.1002/acr.25342

Objective Although hand synovitis is prevalent in the older population, the etiology remains unclear. Hyperuricemia, a modifiable metabolic disorder, may serve as an underlying mechanism of hand synovitis, but little is known about their relationshi... Read More about Association Between Hyperuricemia and Ultrasound-Detected Hand Synovitis.

Melatonin is a potential novel analgesic agent for osteoarthritis: Evidence from cohort studies in humans and preclinical research in rats (2024)
Journal Article
Li, H., Zhou, B., Wu, J., Zhang, Y., Zhang, W., Doherty, M., Deng, X., Wang, N., Xie, D., Wang, Y., Xie, H., Li, C., Wei, J., Lei, G., & Zeng, C. (2024). Melatonin is a potential novel analgesic agent for osteoarthritis: Evidence from cohort studies in humans and preclinical research in rats. Journal of Pineal Research, 76(2), Article e12945. https://doi.org/10.1111/jpi.12945

Melatonin exhibits potential for pain relief and long-term safety profile. We examined the analgesic effects of oral melatonin on osteoarthritis (OA) and investigated the underlying mechanism. Using data from a UK primary care database, we conducted... Read More about Melatonin is a potential novel analgesic agent for osteoarthritis: Evidence from cohort studies in humans and preclinical research in rats.